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Showing 25 to 36 of 436 entries
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Affinity-Based Selectivity Profiling of an In-Class Selective Competitive Inhibitor of Acyl Protein Thioesterase 2.

ACS medicinal chemistry letters

Won SJ, Eschweiler JD, Majmudar JD, Chong FS, Hwang SY, Ruotolo BT, Martin BR.
PMID: 28197315
ACS Med Chem Lett. 2016 Dec 09;8(2):215-220. doi: 10.1021/acsmedchemlett.6b00441. eCollection 2017 Feb 09.

Activity-based protein profiling (ABPP) has revolutionized the discovery and optimization of active-site ligands across distinct enzyme families, providing a robust platform for in-class selectivity profiling. Nonetheless, this approach is less straightforward for profiling reversible inhibitors and does not access...

Frequency of Red Blood Cell Alloimmunization in Patients with Sickle Cell Disease in Palestine.

Advances in hematology

Samarah F, Srour MA, Yaseen D, Dumaidi K.
PMID: 29977298
Adv Hematol. 2018 Jun 06;2018:5356245. doi: 10.1155/2018/5356245. eCollection 2018.

BACKGROUND: Transfusion of red blood cells (RBC) is an essential therapeutic tool in sickle cell disease (SCD). Repeated RBC transfusions can cause alloimmunization which causes difficulty in cross-matching and finding compatible blood for transfusions. This study aimed to investigate...

A case of liver abscesses and porto-enteric fistula caused by an ingested toothpick: A review of the distinctive clinical and imaging features.

Radiology case reports

Martin S, Petraszko AM, Tandon YK.
PMID: 31956387
Radiol Case Rep. 2020 Jan 13;15(3):273-276. doi: 10.1016/j.radcr.2019.12.007. eCollection 2020 Mar.

Though foreign body (FB) ingestions are a relatively common occurrence in the bustling emergency department, particularly among children, the vast majority of FBs either pass uneventfully or can be retrieved endoscopically. Only a small percentage of patients will experience...

Exploring practices of Dermatologists in Ethical Dilemmas in Pakistan: A narrative analysis.

Pakistan journal of medical sciences

Tahir M, Yasmeen R, Khan RA.
PMID: 29805411
Pak J Med Sci. 2018 Mar-Apr;34(2):374-379. doi: 10.12669/pjms.342.14328.

BACKGROUND AND OBJECTIVE: Specialists in dermatology come across ethical issues in their practice. The topic is subjective so dialogue and reflection is required. The main objective of this study was to explore how dermatologists deal with ethical dilemmas in...

Obstetric Outcome in Obese Saudi Pregnant Women: A Cohort Prospective Study at a Teaching Hospital.

Saudi journal of medicine & medical sciences

Haseeb YA.
PMID: 30787772
Saudi J Med Med Sci. 2017 May-Aug;5(2):142-144. doi: 10.4103/1658-631X.204874. Epub 2017 Apr 20.

OBJECTIVE: The objective of this study was to compare obstetrical outcome in obese women with a body mass index (BMI) ≥29.9 kg/mMETHODS: This is a prospective cohort study of 300 Saudi females aged between 20 and 35 years in...

Epidemiology and risk factors of transfusion transmitted infections in thalassemia major: a multicenter study in Pakistan.

Hematology, transfusion and cell therapy

Yasmeen H, Hasnain S.
PMID: 31399357
Hematol Transfus Cell Ther. 2019 Oct - Dec;41(4):316-323. doi: 10.1016/j.htct.2019.03.008. Epub 2019 Jun 28.

BACKGROUND: Blood transfusion-transmitted infections in individuals suffering from beta-thalassemia have been reported in Pakistan, but the information on their sociodemographic and clinical determinants is lacking. This study aims to describe the prevalence, as well as the factors, contributing in...

Complete Genomic Analysis of a .

Frontiers in microbiology

Wang W, Baloch Z, Zou M, Dong Y, Peng Z, Hu Y, Xu J, Yasmeen N, Li F, Fanning S.
PMID: 29755416
Front Microbiol. 2018 Apr 27;9:616. doi: 10.3389/fmicb.2018.00616. eCollection 2018.

One

Pre-operative percutaneous endoscopic gastrostomy tube placement does not increase post-operative complications or mortality in oesophageal cancer.

Journal of gastrointestinal oncology

Siddique MZ, Mehmood S, Ismail M, Yasmeen A, Asad-Ur-Rehman, Abu Bakar M, Khattak S, Syed AA, Yusuf MA.
PMID: 31183199
J Gastrointest Oncol. 2019 Jun;10(3):492-498. doi: 10.21037/jgo.2019.03.08.

BACKGROUND: The percutaneous endoscopic gastrostomy (PEG) tube in patients with oesophageal cancer is controversial, owing to a perceived risk of tumour seeding at the PEG site, theoretical difficulty in formation of gastric conduit during oesophagectomy and a fear of...

Galectin-1 Facilitates Macrophage Reprogramming and Resolution of Inflammation Through IFN-β.

Frontiers in pharmacology

Yaseen H, Butenko S, Polishuk-Zotkin I, Schif-Zuck S, Pérez-Sáez JM, Rabinovich GA, Ariel A.
PMID: 32625094
Front Pharmacol. 2020 Jun 17;11:901. doi: 10.3389/fphar.2020.00901. eCollection 2020.

During the resolution of acute inflammation, macrophages undergo reprogramming from pro-inflammatory, to anti-inflammatory/reparative, and eventually to pro-resolving macrophages. Galectin-1 (Gal-1) is a

Conversion of Imine to Oxazole and Thiazole Linkages in Covalent Organic Frameworks.

Journal of the American Chemical Society

Waller PJ, AlFaraj YS, Diercks CS, Jarenwattananon NN, Yaghi OM.
PMID: 29999317
J Am Chem Soc. 2018 Jul 25;140(29):9099-9103. doi: 10.1021/jacs.8b05830. Epub 2018 Jul 12.

Imine-linked ILCOF-1 based on 1,4-phenylenediamine and 1,3,6,8-tetrakis(4-formylphenyl)pyrene was converted through consecutive linker substitution and oxidative cyclization to two isostructural covalent organic frameworks (COFs), having thiazole and oxazole linkages. The completeness of the conversion was assessed by infrared and solid-state...

Toll-Like Receptors and Relevant Emerging Therapeutics with Reference to Delivery Methods.

Pharmaceutics

Javaid N, Yasmeen F, Choi S.
PMID: 31480568
Pharmaceutics. 2019 Sep 01;11(9). doi: 10.3390/pharmaceutics11090441.

The built-in innate immunity in the human body combats various diseases and their causative agents. One of the components of this system is Toll-like receptors (TLRs), which recognize structurally conserved molecules derived from microbes and/or endogenous molecules. Nonetheless, under...

Maggot Infestation of the Prolapsed Uterus.

Cureus

Hamza M, Yasmeen T, Fatima N, Ahmed Nadeem I.
PMID: 30648086
Cureus. 2018 Nov 06;10(11):e3554. doi: 10.7759/cureus.3554.

Myiasis of the genital organ is a rare clinical entity. It is a very disturbing condition that is linked to poor hygiene and sanitary conditions. Here, we report a case of a 62-year-old postmenopausal female who presented with the...

Showing 25 to 36 of 436 entries