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Showing 637 to 646 of 646 entries
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Discovery of DNA polymorphisms via whole genome resequencing and their functional relevance in salinity stress response in chickpea.

Physiologia plantarum

Rajkumar MS, Jain M, Garg R.
PMID: 34287918
Physiol Plant. 2021 Dec;173(4):1573-1586. doi: 10.1111/ppl.13507. Epub 2021 Jul 28.

Salinity stress is one of the major constraints for plant growth and yield. The salinity stress response of different genotypes of crop plants may largely be governed by DNA polymorphisms. To determine the molecular genetic factors involved in salinity...

The applications of functionalized DNA nanostructures in bioimaging and cancer therapy.

Biomaterials

Zeng Y, Nixon RL, Liu W, Wang R.
PMID: 33285441
Biomaterials. 2021 Jan;268:120560. doi: 10.1016/j.biomaterials.2020.120560. Epub 2020 Nov 23.

Deoxyribonucleic acid (DNA) is a molecular carrier of genetic information that can be fabricated into functional nanomaterials in biochemistry and engineering fields. Those DNA nanostructures, synthesized via Watson-Crick base pairing, show a wide range of attributes along with excellent...

Ancillary Ligand in Ternary Cu.

The journal of physical chemistry. B

Galindo-Murillo R, Winkler L, García-Ramos JC, Ruiz-Azuara L, Cortés-Guzmán F, Cheatham TE.
PMID: 33320672
J Phys Chem B. 2020 Dec 24;124(51):11648-11658. doi: 10.1021/acs.jpcb.0c09296. Epub 2020 Dec 15.

Copper-containing compounds known as Casiopeı́nas are biologically active molecules which show promising antineoplastic effects against several cancer types. Two possible hypotheses regarding the mode of action of the Casiopeı́nas have emerged from the experimental evidence: the generation of reactive...

Combined nanopore adaptive sequencing and enzyme-based host depletion efficiently enriched microbial sequences and identified missing respiratory pathogens.

BMC genomics

Gan M, Wu B, Yan G, Li G, Sun L, Lu G, Zhou W.
PMID: 34627155
BMC Genomics. 2021 Oct 09;22(1):732. doi: 10.1186/s12864-021-08023-0.

BACKGROUND: Enzyme-based host depletion significantly improves the sensitivity of clinical metagenomics. Recent studies found that real-time adaptive sequencing of DNA molecules was achieved using a nanopore sequencing machine, which enabled effective enrichment of microbial sequences. However, few studies have...

Editorial: Single-molecule studies of DNA-protein interactions collection 2021.

Nucleic acids research

Bianco PR, Sale JE, Reyes-Lamothe R.
PMID: 34153108
Nucleic Acids Res. 2021 Jun 21;49(11):6005-6006. doi: 10.1093/nar/gkab497.

No abstract available.

Alterations in the Composition of Intestinal DNA Virome in Patients With COVID-19.

Frontiers in cellular and infection microbiology

Lu ZH, Zhou HW, Wu WK, Fu T, Yan M, He Z, Sun SW, Ji ZH, Shao ZJ.
PMID: 34900762
Front Cell Infect Microbiol. 2021 Nov 24;11:790422. doi: 10.3389/fcimb.2021.790422. eCollection 2021.

Patients with Coronavirus Disease 2019 (COVID-19), due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection mainly present with respiratory issues and related symptoms, in addition to significantly affected digestive system, especially the intestinal tract. While several studies have...

Coarse-Grained Simulations of DNA Reveal Angular Dependence of Sticky-End Binding.

The journal of physical chemistry. B

Gravina NM, Gumbart JC, Kim HD.
PMID: 33870695
J Phys Chem B. 2021 Apr 29;125(16):4016-4024. doi: 10.1021/acs.jpcb.1c00432. Epub 2021 Apr 19.

Annealing between sticky ends of DNA is an intermediate step in ligation. It can also be utilized to program specific binding sites for DNA tile and origami assembly. This reaction is generally understood as a bimolecular reaction dictated by...

DNA-tethered Polymersome Clusters as Nanotheranostic Platform.

Chimia

Meyer CE, Schoenenberger CA, Liu J, Craciun I, Palivan CG.
PMID: 33902798
Chimia (Aarau). 2021 Apr 28;75(4):296-299. doi: 10.2533/chimia.2021.296.

Nanotheranostics combine the use of nanomaterials and biologically active compounds to achieve diagnosis and treatment at the same time. To date, severe limitations compromise the use of nanotheranostic systems as potent nanomaterials are often incompatible with potent biomolecules. Herein...

3D DNA Walker-Assisted CRISPR/Cas12a Trans-Cleavage for Ultrasensitive Electrochemiluminescence Detection of miRNA-141.

Analytical chemistry

Wang Q, Liu Y, Yan J, Liu Y, Gao C, Ge S, Yu J.
PMID: 34553925
Anal Chem. 2021 Oct 05;93(39):13373-13381. doi: 10.1021/acs.analchem.1c03183. Epub 2021 Sep 23.

In this study, a CRISPR/Cas12a (LbCpf1)-mediated electrochemiluminescence (ECL) paper-based platform on the basis of a three-dimensional (3D) DNA walker was proposed for the ultrasensitive detection of miRNA-141. Initially, 3D-rGO with a tremendous loading space was modified on the paper...

Three-dimensional nanolithography guided by DNA modular epitaxy.

Nature materials

Shen J, Sun W, Liu D, Schaus T, Yin P.
PMID: 33846583
Nat Mater. 2021 May;20(5):683-690. doi: 10.1038/s41563-021-00930-7. Epub 2021 Apr 12.

Lithographic scaling of periodic three-dimensional patterns is critical for advancing scalable nanomanufacturing. Current state-of-the-art quadruple patterning or extreme-ultraviolet lithography produce a line pitch down to around 30 nm, which might be further scaled to sub-20 nm through complex post-fabrication...

Showing 637 to 646 of 646 entries