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Showing 13 to 18 of 18 entries
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Computational analysis of protein-DNA interactions from ChIP-seq data.

Methods in molecular biology (Clifton, N.J.)

Rougemont J, Naef F.
PMID: 21938632
Methods Mol Biol. 2012;786:263-73. doi: 10.1007/978-1-61779-292-2_16.

Chromatin immunoprecipitation experiments followed by ultra-high-throughput sequencing (ChIP-seq) is becoming the method of choice to identify transcription factor binding sites in prokaryotes and eukaryotes in vivo. Here, we review the computational steps that are necessary for analyzing the sequenced...

Neuroimaging in frontotemporal lobar degeneration--predicting molecular pathology.

Nature reviews. Neurology

Whitwell JL, Josephs KA.
PMID: 22290573
Nat Rev Neurol. 2012 Jan 31;8(3):131-42. doi: 10.1038/nrneurol.2012.7.

Frontotemporal lobar degeneration (FTLD) encompasses a group of diseases characterized by neuronal loss and gliosis of the frontal and temporal lobes. Almost all cases of FTLD can be classified into three categories on the basis of deposition of one...

Use Chou's 5-Step Rule to Predict DNA-Binding Proteins with Evolutionary Information.

BioMed research international

Lu W, Song Z, Ding Y, Wu H, Cao Y, Zhang Y, Li H.
PMID: 32775434
Biomed Res Int. 2020 Jul 27;2020:6984045. doi: 10.1155/2020/6984045. eCollection 2020.

The knowledge of DNA-binding proteins would help to understand the functions of proteins better in cellular biological processes. Research on the prediction of DNA-binding proteins can promote the research of drug proteins and computer acidified drugs. In recent years,...

Teaching case 3-2019: Are nuclear clefts or invaginations the niche of intranuclear inclusions in FTLD-TDP?.

Clinical neuropathology

Molina-Porcel L, Pérez-Navarro E, García-Forn M, Westaway D, Colom-Cadena M, Gelpi E.
PMID: 31023421
Clin Neuropathol. 2019 May/Jun;38(3):97-99. doi: 10.5414/NP301202.

No abstract available.

PredDBP-Stack: Prediction of DNA-Binding Proteins from HMM Profiles using a Stacked Ensemble Method.

BioMed research international

Wang J, Zheng H, Yang Y, Xiao W, Liu T.
PMID: 32352006
Biomed Res Int. 2020 Apr 13;2020:7297631. doi: 10.1155/2020/7297631. eCollection 2020.

DNA-binding proteins (DBPs) play vital roles in all aspects of genetic activities. However, the identification of DBPs by using wet-lab experimental approaches is often time-consuming and laborious. In this study, we develop a novel computational method, called PredDBP-Stack, to...

Editorial: Single-molecule studies of DNA-protein interactions collection 2021.

Nucleic acids research

Bianco PR, Sale JE, Reyes-Lamothe R.
PMID: 34153108
Nucleic Acids Res. 2021 Jun 21;49(11):6005-6006. doi: 10.1093/nar/gkab497.

No abstract available.

Showing 13 to 18 of 18 entries