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Showing 1 to 12 of 240 entries
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Allele-specific transcriptional activity of the variable number of tandem repeats of the inducible nitric oxide synthase gene is associated with idiopathic achalasia.

United European gastroenterology journal

Sarnelli G, Grosso M, Palumbo I, Pesce M, D'Alessandro A, Zaninotto G, Annese V, Petruzzelli R, Izzo P, Sepulveres R, Bruzzese D, Esposito G, Cuomo R.
PMID: 28344787
United European Gastroenterol J. 2017 Mar;5(2):200-207. doi: 10.1177/2050640616648870. Epub 2016 Jul 08.

BACKGROUND: Polymorphisms of genes involved in the regulation of the immune response are risk factors for achalasia, but their contribution to disease pathogenesis is unknown. Nitric oxide is involved both in immune function and inhibitory neurotransmission.OBJECTIVE: The objective of...

Severe Type 2 Diabetes Induces Reversible Modifications of Endothelial Progenitor Cells Which are Ameliorate by Glycemic Control.

International journal of stem cells

De Pascale MR, Bruzzese G, Crimi E, Grimaldi V, Liguori A, Brongo S, Barbieri M, Picascia A, Schiano C, Sommese L, Ferrara N, Paolisso G, Napoli C.
PMID: 27426095
Int J Stem Cells. 2016 May 30;9(1):137-44. doi: 10.15283/ijsc.2016.9.1.137.

BACKGROUND: Circulating endothelial progenitors cells (EPCs) play a critical role in neovascularization and endothelial repair. There is a growing evidence that hyperglycemia related to Diabetes Mellitus (DM) decreases EPC number and function so promoting vascular complications.AIM OF THE STUDY:...

Successful Management of Pregnancy and Hepatic Toxicity in a CML Female Patient Treated with Nilotinib: a Case Report and a Review.

Mediterranean journal of hematology and infectious diseases

Santorsola D, Abruzzese E.
PMID: 25745547
Mediterr J Hematol Infect Dis. 2015 Feb 15;7(1):e2015020. doi: 10.4084/MJHID.2015.020. eCollection 2015.

We report a case of a young patient with chronic viral hepatitis HBV infection, diagnosed with CML in March 2006 and treated with imatinib 400mg/die as first line therapy with concomitant Lamivudine. Patient obtained a complete hematologic response (CHR)...

Postural Stabilization Strategies to Motor Contagion Induced by Action Observation Are Impaired in Parkinson's Disease.

Frontiers in neurology

Pelosin E, Bisio A, Pozzo T, Lagravinese G, Crisafulli O, Marchese R, Abbruzzese G, Avanzino L.
PMID: 29545771
Front Neurol. 2018 Mar 01;9:105. doi: 10.3389/fneur.2018.00105. eCollection 2018.

Postural reactions can be influenced by concomitant tasks or different contexts and are modulated by a higher order motor control. Recent studies investigated postural changes determined by motor contagion induced by action observation (chameleon effect) showing that observing a...

Sleep-disordered breathing, impaired cardiac adrenergic innervation and prognosis in heart failure.

Heart (British Cardiac Society)

Scala O, Paolillo S, Formisano R, Pellegrino T, Rengo G, Gargiulo P, De Michele F, Starace A, Rapacciuolo A, Parisi V, Prastaro M, Piscopo V, Dellegrottaglie S, Bruzzese D, De Martino F, Parente A, Leosco D, Trimarco B, Cuocolo A, Perrone-Filardi P.
PMID: 27340199
Heart. 2016 Nov 15;102(22):1813-1819. doi: 10.1136/heartjnl-2015-309215. Epub 2016 Jun 23.

OBJECTIVE: Unfavourable effects of sleep-disordered breathing (SDB) in heart failure (HF) are mainly mediated by impaired sympathetic activity. Few data are available on SDB and cardiac adrenergic impairment evaluated at myocardial level. The aim of the study was to...

Tyrosine kinase inhibitors and pregnancy.

Mediterranean journal of hematology and infectious diseases

Abruzzese E, Trawinska MM, Perrotti AP, De Fabritiis P.
PMID: 24804001
Mediterr J Hematol Infect Dis. 2014 Apr 07;6(1):e2014028. doi: 10.4084/MJHID.2014.028. eCollection 2014.

The management of patients with chronic myeloid leukemia (CML) during pregnancy has become recently a matter of continuous debate. The introduction of the Tyrosine Kinase Inhibitors (TKIs) in clinical practice has dramatically changed the prognosis of CML patients; in...

Laser ablation of silicon induced by a femtosecond optical vortex beam.

Optics letters

Nivas JJ, Shutong H, Anoop KK, Rubano A, Fittipaldi R, Vecchione A, Paparo D, Marrucci L, Bruzzese R, Amoruso S.
PMID: 26469576
Opt Lett. 2015 Oct 15;40(20):4611-4. doi: 10.1364/OL.40.004611.

We investigate laser ablation of crystalline silicon induced by a femtosecond optical vortex beam, addressing how beam properties can be obtained by analyzing the ablation crater. The morphology of the surface structures formed in the annular crater surface allows...

Toxicity and Efficacy of Concurrent Gemcitabine and Radiotherapy for Locally Advanced Pancreatic Cancer.

International journal of gastrointestinal cancer

Crane C, Janjan N, Evans D, Wolff R, Ballo M, Milas L, Mason K, Charnsangavej C, Pisters P, Lee J, Lenzi R, Vauthey J, Wong A, Phan T, Nguyen Q, Abbruzzese J.
PMID: 12754400
Int J Gastrointest Cancer. 2001;29(1):9-18.

Gemcitabine has been demonstrated to be a potentradiosensitizer in the laboratory and in the clinic (1-7)and has proven clinical systemic activity to pancreaticcancer. Responses to systemic gemcitabine inpatients with metastatic pancreatic adenocarcinomahave been documented in phase I, phase II,...

A Novel, Clinically Relevant Animal Model of Metastatic Pancreatic Adenocarcinoma Biology and Therapy.

International journal of gastrointestinal cancer

Wang B, Shi Q, Abbruzzese J, Xiong Q, Le X, Xie K.
PMID: 12754403
Int J Gastrointest Cancer. 2001;29(1):37-46.

In this study, we report a metastatic model of Panc02 murine pancreatic adenocarcinoma. Parental Panc02cells were orthotopically implanted into the pancreas of syngeneic C57BL/6 mice. Tumor cells were isolatedfrom liver micrometastases 90 d after tumor implantation and established as...

Continuing education needs of faculty.

Deans Notes

Abruzzese RS.
PMID: 6559108
Deans Notes. 1984 Jan;5(3):1-2.

No abstract available.

COMT inhibition with tolcapone in the treatment algorithm of patients with Parkinson's disease (PD): relevance for motor and non-motor features.

Neuropsychiatric disease and treatment

Antonini A, Abbruzzese G, Barone P, Bonuccelli U, Lopiano L, Onofrj M, Zappia M, Quattrone A.
PMID: 18728767
Neuropsychiatr Dis Treat. 2008 Feb;4(1):1-9. doi: 10.2147/ndt.s2404.

Levodopa is the most effective treatment in Parkinson's disease and the association with COMT inhibitors widens its plasma bioavailability and effectiveness. Tolcapone is a potent COMT inhibitor whose utilization in PD is limited due to safety concerns on liver...

Focal dystonia in musicians: linking motor symptoms to somatosensory dysfunction.

Frontiers in human neuroscience

Konczak J, Abbruzzese G.
PMID: 23805090
Front Hum Neurosci. 2013 Jun 25;7:297. doi: 10.3389/fnhum.2013.00297. eCollection 2013.

Musician's dystonia (MD) is a neurological motor disorder characterized by involuntary contractions of those muscles involved in the play of a musical instrument. It is task-specific and initially only impairs the voluntary control of highly practiced musical motor skills....

Showing 1 to 12 of 240 entries