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Showing 1 to 12 of 20 entries
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More Than an Association: Latent Toxoplasmosis Might Provoke a Local Oxidative Stress That Triggers the Development of Bipolar Disorder.

Journal of microscopy and ultrastructure

Afifi MA, Jiman-Fatani AA, Al-Rabia MW, Al-Hussainy NH, El Saadany S, Mayah W.
PMID: 30221140
J Microsc Ultrastruct. 2018 Jul-Sep;6(3):139-144. doi: 10.4103/JMAU.JMAU_22_18.

CONCLUSION: These findings might indicate a role for

Attitudes toward the SARS-CoV-2 Vaccine: Results from the Saudi Residents' Intention to Get Vaccinated against COVID-19 (SRIGVAC) Study.

Vaccines

Alzahrani SH, Baig M, Alrabia MW, Algethami MR, Alhamdan MM, Alhakamy NA, Asfour HZ, Ahmad T.
PMID: 34358214
Vaccines (Basel). 2021 Jul 18;9(7). doi: 10.3390/vaccines9070798.

Vaccine uptake could influence vaccination efforts to control the widespread COVID-19 pandemic; however, little is known about vaccine acceptance in Saudi Arabia. The present study aimed to assess the Saudi public's intent to get vaccinated against COVID-19 and explore...

Cardiac Injury Biomarkers and the Risk of Death in Patients with COVID-19: A Systematic Review and Meta-Analysis.

Cardiology research and practice

Alzahrani SH, Al-Rabia MW.
PMID: 33815838
Cardiol Res Pract. 2021 Mar 18;2021:9363569. doi: 10.1155/2021/9363569. eCollection 2021.

BACKGROUND: Cardiac complications may develop in a proportion of patients with the novel coronavirus disease (COVID-19), which may influence their prognosis.OBJECTIVES: To assess the role of cardiac injury biomarkers measured on admission and during hospitalization as risk factors for...

Piceatannol-Loaded Emulsomes Exhibit Enhanced Cytostatic and Apoptotic Activities in Colon Cancer Cells.

Antioxidants (Basel, Switzerland)

Alhakamy NA, Badr-Eldin SM, Ahmed OAA, Asfour HZ, Aldawsari HM, Algandaby MM, Eid BG, Abdel-Naim AB, Awan ZA, Alghaith AF, Alaofi AL, Mohamed AI, Okbazghi SZ, Al-Rabia MW, Fahmy UA.
PMID: 32414040
Antioxidants (Basel). 2020 May 13;9(5). doi: 10.3390/antiox9050419.

Piceatannol (PIC), a naturally occurring polyphenolic stilbene, has pleiotropic pharmacological activities. It has reported cytotoxic activities against different cancer cells. In the present study, PIC emulsomes (PIC-E) were formulated and assessed for cytotoxic activity. A Box-Behnken design was employed...

The Enhanced Cytotoxic and Pro-Apoptotic Effects of Optimized Simvastatin-Loaded Emulsomes on MCF-7 Breast Cancer Cells.

Pharmaceutics

Awan ZA, Fahmy UA, Badr-Eldin SM, Ibrahim TS, Asfour HZ, Al-Rabia MW, Alfarsi A, Alhakamy NA, Abdulaal WH, Al Sadoun H, Helmi N, Noor AO, Caraci F, Almasri DM, Caruso G.
PMID: 32604984
Pharmaceutics. 2020 Jun 27;12(7). doi: 10.3390/pharmaceutics12070597.

Statins, including simvastatin (SMV), are commonly used for the control of hyperlipidaemia and have also proven therapeutic and preventative effects in cardiovascular diseases. Besides that, there is an emerging interest in their use as antineoplastic drugs as demonstrated by...

In vitro inhibitory analysis of consensus siRNAs against NS3 gene of hepatitis C virus 1a genotype.

Asian Pacific journal of tropical medicine

Shahid I, AlMalki WH, AlRabia MW, Mukhtar MH, Almalki SSR, Alkahtani SA, Ashgar SS, Faidah HS, Hafeez MH.
PMID: 28870347
Asian Pac J Trop Med. 2017 Jul;10(7):701-709. doi: 10.1016/j.apjtm.2017.07.011. Epub 2017 Aug 08.

OBJECTIVE: To explore inhibitory effects of genome-specific, chemically synthesized siRNAs (small interference RNA) against NS3 gene of hepatitis C virus (HCV) 1a genotype in stable Huh-7 (human hepatoma) cells as well as against viral replication in serum-inoculated Huh-7 cells.METHODS:...

Imaging findings of spontaneous perforation of common bile duct in an infant.

Annals of Saudi medicine

Rifai A, Shabib SM, Al-Rabia A.
PMID: 17344685
Ann Saudi Med. 1998 Jul-Aug;18(4):335-6. doi: 10.5144/0256-4947.1998.335.

No abstract available.

2-Methoxy-estradiol Loaded Alpha Lipoic Acid Nanoparticles Augment Cytotoxicity in MCF-7 Breast Cancer Cells.

Dose-response : a publication of International Hormesis Society

Alhakamy NA, Al-Rabia MW, Asfour HZ, Alshehri S, Alharbi WS, Halawani A, Alamoudi AJ, Noor AO, Bannan DF, Fahmy UA, Kotta S.
PMID: 34987331
Dose Response. 2021 Dec 09;19(4):15593258211055023. doi: 10.1177/15593258211055023. eCollection 2021.

The therapeutic effectiveness of anticancer drugs with a selective target for the nucleus of cancer cells may be improved by experimental approaches. In this regard, the formulation of anticancer drugs is considered one of the best ways to improve...

The immunomodulatory effects of rolipram abolish drug-resistant latent phase of .

Journal of microscopy and ultrastructure

Afifi MA, Al-Rabia MW.
PMID: 30023187
J Microsc Ultrastruct. 2015 Apr-Jun;3(2):86-91. doi: 10.1016/j.jmau.2014.12.001. Epub 2015 Jan 07.

BACKGROUND: Latent toxoplasmosis always has the risk of reactivation leading to significant sequelae. The available medications, for chronic toxoplasmosis, are awfully limited by resistance of MATERIALS AND METHODS: Mice infected with low pathogenic strain of RESULTS: Rolipram was partially...

Anti-inflammatory ergosterol derivatives from the endophytic fungus .

Natural product research

Al-Rabia MW, Mohamed GA, Ibrahim SRM, Asfour HZ.
PMID: 32375510
Nat Prod Res. 2021 Dec;35(23):5011-5020. doi: 10.1080/14786419.2020.1762185. Epub 2020 May 06.

Two new ergosterol derivatives namely, chlamydosterols A [(22

The role of caspase activation and mitochondrial depolarisation in cultured human apoptotic eosinophils.

Saudi journal of biological sciences

Alenzi FQ, Alenazi BQ, Al-Anazy FH, Mubaraki AM, Salem ML, Al-Jabri AA, Lotfy M, Bamaga MS, Alrabia MW, Wyse RK.
PMID: 23961055
Saudi J Biol Sci. 2010 Jan;17(1):29-36. doi: 10.1016/j.sjbs.2009.12.005.

Caspases are key intracellular molecules in the control of apoptosis, but little is known concerning their relative contribution to the cascade of events leading to eosinophil apoptosis. We examined caspase-3, -8, and -9 activities in receptor ligation dependent apoptosis...

Optimisation of proteomic approaches to study the maternal interaction with gametes in sow's reproductive tract.

Journal of microscopy and ultrastructure

Aldarmahi A, Al-Rabia M.
PMID: 30023194
J Microsc Ultrastruct. 2015 Jul-Sep;3(3):154-160. doi: 10.1016/j.jmau.2015.02.001. Epub 2015 Mar 27.

The applications of 2DE and MS have been successfully used in many studies utilising different biological samples. The complex nature of cellular proteomes is a big challenge for proteomic technologies. Much effort has been applied to develop and improve...

Showing 1 to 12 of 20 entries