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Showing 1 to 12 of 28 entries
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Humans differ in their personal microbial cloud.

PeerJ

Meadow JF, Altrichter AE, Bateman AC, Stenson J, Brown GZ, Green JL, Bohannan BJ.
PMID: 26417541
PeerJ. 2015 Sep 22;3:e1258. doi: 10.7717/peerj.1258. eCollection 2015.

Dispersal of microbes between humans and the built environment can occur through direct contact with surfaces or through airborne release; the latter mechanism remains poorly understood. Humans emit upwards of 10(6) biological particles per hour, and have long been...

Total IgE as a Marker for Chronic Spontaneous Urticaria.

Allergy, asthma & immunology research

Altrichter S, Fok JS, Jiao Q, Kolkhir P, Pyatilova P, Romero SM, Scheffel J, Siebenhaar F, Steinert C, Terhorst-Molawi D, Xiang YK, Church MK, Maurer M.
PMID: 33474856
Allergy Asthma Immunol Res. 2021 Mar;13(2):206-218. doi: 10.4168/aair.2021.13.2.206.

OBJECTIVE: Immunoglobulin E (IgE) and its receptor, FcɛRI, importantly contribute to the pathophysiology of chronic spontaneous urticaria (CSU). Recent findings point to a possible role of total IgE as a marker of CSU disease activity, endotypes, and responses to...

Answers to burning questions for clinical allergologists related to the new COVID-19 vaccines.

Allergo journal international

Altrichter S, Wöhrl S, Horak F, Idzko M, Jordakieva G, Untersmayr E, Szepfalusi Z, Zieglmayer P, Jensen-Jarolim E, Wiedermann U, Rosenkranz A, Hötzenecker W.
PMID: 34277326
Allergo J Int. 2021 Jul 14;1-7. doi: 10.1007/s40629-021-00177-3. Epub 2021 Jul 14.

BACKGROUND: Along with the newly approved vaccines against coronavirus disease 2019 (COVID-19), first reports of allergic or intolerance reactions were published. Subsequently, questions arose whether these vaccines pose an increased risk for intolerance reactions and whether allergic patients may...

Prolonged storage of purified granulocyte concentrates: Introduction of a new purification method.

Transfusion

Klinkmann G, Doss F, Goudeva L, Doss S, Blasczyk R, Milej M, Koch S, Mitzner S, Altrichter J.
PMID: 34783358
Transfusion. 2022 Jan;62(1):194-204. doi: 10.1111/trf.16732. Epub 2021 Nov 16.

BACKGROUND: Use of donor granulocyte concentrate (GC) has been limited due to its short storage time of 6-24 h, which is partially due to residual red blood cells (RBCs) and platelets and the resulting lactate production leading to an...

Diagnosis and treatment of chronic inducible urticaria.

Allergy

Maurer M, Hawro T, Krause K, Magerl M, Metz M, Siebenhaar F, Terhorst-Molawi D, Weller K, Zuberbier T, Altrichter S.
PMID: 31102545
Allergy. 2019 Dec;74(12):2550-2553. doi: 10.1111/all.13878. Epub 2019 Jun 02.

No abstract available.

Bacterial communities on classroom surfaces vary with human contact.

Microbiome

Meadow JF, Altrichter AE, Kembel SW, Moriyama M, O'Connor TK, Womack AM, Brown GZ, Green JL, Bohannan BJ.
PMID: 24602274
Microbiome. 2014 Mar 07;2(1):7. doi: 10.1186/2049-2618-2-7.

BACKGROUND: Humans can spend the majority of their time indoors, but little is known about the interactions between the human and built-environment microbiomes or the forces that drive microbial community assembly in the built environment. We sampled 16S rRNA...

Behind the Menu.

American journal of public health and the nation's health

Trichter J.
PMID: 18017235
Am J Public Health Nations Health. 1950 Sep;40(9):1155. doi: 10.2105/ajph.40.9.1155-b.

No abstract available.

Neutrophil-derived circulating free DNA (cf-DNA/NETs), a potential prognostic marker for mortality in patients with severe burn injury.

European journal of trauma and emergency surgery : official publication of the European Trauma Society

Altrichter J, Zedler S, Kraft R, Faist E, Mitzner SR, Sauer M, Windolf J, Scholz M, Lögters T.
PMID: 26816310
Eur J Trauma Emerg Surg. 2010 Dec;36(6):551-7. doi: 10.1007/s00068-010-0013-1. Epub 2010 Mar 17.

The predictive value of circulating free DNA/neutrophil extracellular traps (cf-DNA/NETs) has recently been shown in patients with major trauma for sepsis, multiple organ failure, and mortality. Here we report on the predictive potential of cf-DNA/NETs for mortality in patients...

An Open-Label, Proof-of-Concept Study of Lirentelimab for Antihistamine-Resistant Chronic Spontaneous and Inducible Urticaria.

The Journal of allergy and clinical immunology

Altrichter S, Staubach P, Pasha M, Singh B, Chang AT, Bernstein JA, Rasmussen HS, Siebenhaar F, Maurer M.
PMID: 34954198
J Allergy Clin Immunol. 2021 Dec 23; doi: 10.1016/j.jaci.2021.12.772. Epub 2021 Dec 23.

BACKGROUND: Chronic urticaria (CU) is a debilitating mast cell-driven disease, often refractory to standard therapy (i.e., antihistamines). Lirentelimab, an anti-Siglec-8 monoclonal antibody, selectively inhibits mast cells and depletes eosinophils.OBJECTIVE: Determine safety and efficacy of lirentelimab in patients with chronic...

Toward conditional control of Smac mimetic activity by RNA-templated reduction of azidopeptides on PNA or 2'-OMe-RNA.

Biopolymers

Altrichter Y, Schöller J, Seitz O.
PMID: 34287823
Biopolymers. 2021 Dec;112(12):e23466. doi: 10.1002/bip.23466. Epub 2021 Jul 19.

Oligonucleotide templated reactions can be used to control the activity of functional molecules based on the presence of a specific trigger sequence. We report an RNA-controlled reaction system to conditionally restore the N-terminal amino group and thus binding affinity...

Omalizumab in chronic inducible urticaria: A real-life study of efficacy, safety, predictors of treatment outcome and time to response.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

Yu M, Terhorst-Molawi D, Altrichter S, Hawro T, Chen YD, Liu B, Song XT, Zhao ZT, Maurer M.
PMID: 33522024
Clin Exp Allergy. 2021 May;51(5):730-734. doi: 10.1111/cea.13838. Epub 2021 Feb 08.

No abstract available.

Autoimmune Diseases Are Linked to Type IIb Autoimmune Chronic Spontaneous Urticaria.

Allergy, asthma & immunology research

Kolkhir P, Altrichter S, Asero R, Daschner A, Ferrer M, Giménez-Arnau A, Hawro T, Jakob T, Kinaciyan T, Kromminga A, Konstantinou GN, Makris M, Metz M, Skov PS, Staubach P, Sussman G, Zhang K, Maurer M.
PMID: 34212543
Allergy Asthma Immunol Res. 2021 Jul;13(4):545-559. doi: 10.4168/aair.2021.13.4.545.

PURPOSE: Patients with chronic spontaneous urticaria (CSU) have an increased risk for comorbid autoimmune diseases. In this retrospective multicenter study of CSU patients, we evaluated clinical and laboratory features of CSU associated with a higher risk of comorbid autoimmune...

Showing 1 to 12 of 28 entries