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Showing 1 to 12 of 143 entries
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Novel verbal fluency scores and structural brain imaging for prediction of cognitive outcome in mild cognitive impairment.

Alzheimer's & dementia (Amsterdam, Netherlands)

Clark DG, McLaughlin PM, Woo E, Hwang K, Hurtz S, Ramirez L, Eastman J, Dukes RM, Kapur P, DeRamus TP, Apostolova LG.
PMID: 27239542
Alzheimers Dement (Amst). 2016 Feb 15;2:113-22. doi: 10.1016/j.dadm.2016.02.001. eCollection 2016.

INTRODUCTION: The objective of this study was to assess the utility of novel verbal fluency scores for predicting conversion from mild cognitive impairment (MCI) to clinical Alzheimer's disease (AD).METHOD: Verbal fluency lists (animals, vegetables, F, A, and S) from...

Deep vein thrombosis, ecythyma gangrenosum and heparin-induced thrombocytopenia occurring in a man with a heterozygous Factor V Leiden mutation.

Hematology reports

Apostolova M, Weng B, Pote HH, Ashcraft H, Goldblatt C, Woolley PV.
PMID: 23355938
Hematol Rep. 2012 Nov 19;4(4):e20. doi: 10.4081/hr.2012.e20.

Skin necrosis and limb gangrene are occasional thrombotic manifestations of anticoagulation therapy. We report a man heterozygous for the Factor V Leiden (FVL) mutation, and with a history of recurrent deep venous thrombosis, who initially presented with a necrotic...

A rare case of infectious mononucleosis complicated by guillain-barre syndrome.

Neurology international

Kennedy M, Apostolova M.
PMID: 23888210
Neurol Int. 2013 Jun 27;5(2):20-2. doi: 10.4081/ni.2013.e7. Print 2013 Jun 25.

Infectious mononucleosis is a clinical syndrome characterized by fever, lymphadenopathy and pharyngitis. Neurologic complications of infectious mononucleosis, such as the development of Guillain-Barre syndrome, have been rarely reported and usually present late in the course of the disease. We...

Olfactory identification in subjective cognitive decline and mild cognitive impairment: Association with tau but not amyloid positron emission tomography.

Alzheimer's & dementia (Amsterdam, Netherlands)

Risacher SL, Tallman EF, West JD, Yoder KK, Hutchins GD, Fletcher JW, Gao S, Kareken DA, Farlow MR, Apostolova LG, Saykin AJ.
PMID: 29159268
Alzheimers Dement (Amst). 2017 Sep 23;9:57-66. doi: 10.1016/j.dadm.2017.09.001. eCollection 2017.

INTRODUCTION: We investigated the association between olfactory identification and Alzheimer's disease biomarkers, including amyloid, tau, and neurodegeneration.METHODS: Thirty-four older adults, including 19 cognitively normal (CN), 10 subjective cognitive decline (SCD), and 5 mild cognitive impairment, underwent amyloid positron emission...

An investigation of the relation between tumor-to-liver ratio (TLR) and tumor-to-blood standard uptake ratio (SUR) in oncological FDG PET.

EJNMMI research

Hofheinz F, Bütof R, Apostolova I, Zöphel K, Steffen IG, Amthauer H, Kotzerke J, Baumann M, van den Hoff J.
PMID: 26936768
EJNMMI Res. 2016 Dec;6(1):19. doi: 10.1186/s13550-016-0174-y. Epub 2016 Mar 02.

BACKGROUND: The standardized uptake value (SUV) is the nearly exclusive means for quantitative evaluation of clinical [18F-]fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) whole body investigations. However, the SUV methodology has well-known shortcomings. In this context, it has been recognized...

Cognitive Correlates of Hippocampal Atrophy and Ventricular Enlargement in Adults with or without Mild Cognitive Impairment.

Dementia and geriatric cognitive disorders extra

Goukasian N, Porat S, Blanken A, Avila D, Zlatev D, Hurtz S, Hwang KS, Pierce J, Joshi SH, Woo E, Apostolova LG.
PMID: 31572424
Dement Geriatr Cogn Dis Extra. 2019 Aug 13;9(2):281-293. doi: 10.1159/000490044. eCollection 2019.

We analyzed structural magnetic resonance imaging data from 58 cognitively normal and 101 mild cognitive impairment subjects. We used a general linear regression model to study the association between cognitive performance with hippocampal atrophy and ventricular enlargement using the...

Prediction of Lipophilicity and Pharmacokinetics of Chloroacetamides by Chemometric Approach.

Iranian journal of pharmaceutical research : IJPR

Vastag G, Apostolov S, Matijević B.
PMID: 29755543
Iran J Pharm Res. 2018;17(1):100-114.

In this study, the existence of biological potential of selected

Long-term safety and efficacy of tenofovir disoproxil fumarate substitution for hepatitis B immunoglobulin following liver transplantation.

JGH open : an open access journal of gastroenterology and hepatology

Vasudevan A, Ardalan ZS, Ahmed N, Apostolov R, Gow PJ, Testro AG, Gane EJ, Angus PW.
PMID: 30619939
JGH Open. 2018 Sep 19;2(6):288-294. doi: 10.1002/jgh3.12086. eCollection 2018 Dec.

BACKGROUND AND AIMS: Limitations to the use of long-term Hepatitis B Immunoglobulin (HBIg) following liver transplantation for hepatitis B (HBV) have led to the substitution of HBIg with oral nucleo(s)tide analogue prophylaxis. We prospectively assessed the long-term safety and...

The Role of Melatonin on Behavioral Changes and Concomitant Oxidative Stress in icvAβ.

International journal of molecular sciences

Tzoneva R, Georgieva I, Ivanova N, Uzunova V, Nenchovska Z, Apostolova S, Stoyanova T, Tchekalarova J.
PMID: 34884567
Int J Mol Sci. 2021 Nov 25;22(23). doi: 10.3390/ijms222312763.

One of the pathological hallmarks of Alzheimer's disease (AD) associated with its progression that contributes to β-amyloid (Aβ) generation is oxidative stress (OS). Clinical data suggest that melatonin is a potent antioxidant that might be effective in the adjunctive...

Corrigendum to: A systematic review and meta-analysis to inform cancer screening guidelines in idiopathic inflammatory myopathies.

Rheumatology (Oxford, England)

Oldroyd AGS, Allard AB, Callen JP, Chinoy H, Chung L, Fiorentino D, George MD, Gordon P, Kolstad K, Kurtzman DJB, Machado PM, McHugh NJ, Postolova A, Selva-O'Callaghan A, Schmidt J, Tansley S, Vleugels RA, Werth VP, Aggarwal R.
PMID: 34689208
Rheumatology (Oxford). 2021 Nov 03;60(11):5483. doi: 10.1093/rheumatology/keab616.

No abstract available.

New Heterocyclic Combretastatin A-4 Analogs: Synthesis and Biological Activity of Styryl-2(3.

Pharmaceuticals (Basel, Switzerland)

Atanasov G, Rusew RI, Gelev VM, Chanev CD, Nikolova R, Shivachev BL, Petrov OI, Apostolova MD.
PMID: 34959731
Pharmaceuticals (Basel). 2021 Dec 20;14(12). doi: 10.3390/ph14121331.

Here, we describe the synthesis, characterization, and biological activities of a series of 26 new styryl-2(3H)-benzothiazolone analogs of combretastatin-A4 (CA-4). The cytotoxic activities of these compounds were tested in several cell lines (EA.hy926, A549, BEAS-2B, MDA-MB-231, HT-29, MCF-7, and...

Brain FDG PET for Short- to Medium-Term Prediction of Further Cognitive Decline and Need for Assisted Living in Acutely Hospitalized Geriatric Patients With Newly Detected Clinically Uncertain Cognitive Impairment.

Clinical nuclear medicine

Lange C, Mäurer A, Suppa P, Apostolova I, Steffen IG, Grothe MJ, Buchert R.
PMID: 35006106
Clin Nucl Med. 2022 Feb 01;47(2):123-129. doi: 10.1097/RLU.0000000000003981.

PURPOSE: The aim of this study was to evaluate brain FDG PET for short- to medium-term prediction of cognitive decline, need for assisted living, and survival in acutely hospitalized geriatric patients with newly detected clinically uncertain cognitive impairment (CUCI).MATERIALS...

Showing 1 to 12 of 143 entries