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Showing 1 to 12 of 17 entries
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Latest development in the synthesis of ursodeoxycholic acid (UDCA): a critical review.

Beilstein journal of organic chemistry

Tonin F, Arends IWCE.
PMID: 29520309
Beilstein J Org Chem. 2018 Feb 20;14:470-483. doi: 10.3762/bjoc.14.33. eCollection 2018.

Ursodeoxycholic acid (UDCA) is a pharmaceutical ingredient widely used in clinics. As bile acid it solubilizes cholesterol gallstones and improves the liver function in case of cholestatic diseases. UDCA can be obtained from cholic acid (CA), which is the...

Selenium-catalyzed oxidations with aqueous hydrogen peroxide. 2. Baeyer-Villiger reactions in homogeneous solution.

The Journal of organic chemistry

ten Brink GJ, Vis JM, Arends IW, Sheldon RA.
PMID: 11281784
J Org Chem. 2001 Apr 06;66(7):2429-33. doi: 10.1021/jo0057710.

Several diselenides were tested for catalytic activity in Baeyer-Villiger reactions with 60% aqueous hydrogen peroxide. Bis[3,5-bis(trifluoromethyl)phenyl] diselenide forms the corresponding 3,5-bis(trifluoromethyl)benzene seleninic acid in situ, which is a highly reactive and selective catalyst for the oxidation of carbonyl compounds...

The Baeyer-Villiger reaction: new developments toward greener procedures.

Chemical reviews

ten Brink GJ, Arends IW, Sheldon RA.
PMID: 15352787
Chem Rev. 2004 Sep;104(9):4105-24. doi: 10.1021/cr030011l.

No abstract available.

Efficient immobilisation of Rh-MonoPhos on the aluminosilicate AlTUD-1.

Chemical communications (Cambridge, England)

Simons C, Hanefeld U, Arends IW, Minnaard AJ, Maschmeyer T, Sheldon RA.
PMID: 15599428
Chem Commun (Camb). 2004 Dec 21;(24):2830-1. doi: 10.1039/b411506f. Epub 2004 Oct 26.

Rhodium-MonoPhos was successfully immobilised by ionic interactions on aluminosilicate AlTUD-1. The resulting new heterogeneous catalyst can be used in water and showed excellent enantioselectivity and activity in the asymmetric hydrogenation of methyl-2-acetamidoacrylate.

Photoenzymatic epoxidation of styrenes.

Chemical communications (Cambridge, England)

van Schie MMCH, Paul CE, Arends IWCE, Hollmann F.
PMID: 30666998
Chem Commun (Camb). 2019 Feb 05;55(12):1790-1792. doi: 10.1039/c8cc08149b.

Two-component-diffusible-flavomonooxygenases are versatile biocatalysts for selective epoxidation-, hydroxylation- or halogenation reactions. Their complicated molecular architecture can be simplified using photochemical regeneration of the catalytically active, reduced FADH2 prosthetic group. In this contribution we provide the proof-of-concept and characterization for...

Green, catalytic oxidation of alcohols in water.

Science (New York, N.Y.)

ten Brink GJ, Arends IW, Sheldon RA.
PMID: 10698735
Science. 2000 Mar 03;287(5458):1636-9. doi: 10.1126/science.287.5458.1636.

Alcohol oxidations are typically performed with stoichiometric reagents that generate heavy-metal waste and are usually run in chlorinated solvents. A water-soluble palladium(II) bathophenanthroline complex is a stable recyclable catalyst for the selective aerobic oxidation of a wide range of...

Biocatalytic synthesis of the Green Note .

Beilstein journal of organic chemistry

van Schie MMCH, Pedroso de Almeida T, Laudadio G, Tieves F, Fernández-Fueyo E, Noël T, Arends IWCE, Hollmann F.
PMID: 29719567
Beilstein J Org Chem. 2018 Mar 26;14:697-703. doi: 10.3762/bjoc.14.58. eCollection 2018.

The biocatalytic preparation of

Highly efficient use of NaOCl in the Ru-catalysed oxidation of aliphatic ethers to esters.

Chemical communications (Cambridge, England)

Gonsalvi L, Arends IW, Sheldon RA.
PMID: 12120367
Chem Commun (Camb). 2002 Feb 07;(3):202-3. doi: 10.1039/b109390h.

The selectivity of alpha-oxidation of ethers to esters via Ru-NaOCl can be dramatically improved by pH control, at high substrate to catalyst ratios using a stoichiometric amount of hypochlorite in biphasic media at room temperature.

The surprisingly facile thermal dehalogenation of chlorinated aromatics by a hydroaromatic donor solvent. Tautomerization of chlorinated phenols and anilines.

The Journal of organic chemistry

Mulder P, Arends IW, Santoro D, Korth HG.
PMID: 12762723
J Org Chem. 2003 May 30;68(11):4247-57. doi: 10.1021/jo0265885.

Up to 600 K, chlorinated benzenes and naphthalenes are inert in a hydrogen atom donating solvent such as 9,10-dihydroanthracene. However, when a hydroxyl or amine group is attached to the 2 or 4 position relative to chlorine, a surprisingly...

Copper(II)-catalysed aerobic oxidation of primary alcohols to aldehydes.

Chemical communications (Cambridge, England)

Gamez P, Arends IW, Reedijk J, Sheldon RA.
PMID: 14587708
Chem Commun (Camb). 2003 Oct 07;(19):2414-5. doi: 10.1039/b308668b.

[CuBr2(2,2'-bipyridine)] catalyses the selective and very mild aerobic oxidation of primary alcohols to aldehydes in acetonitrile:water (2:1) in the presence of 2,2,6,6-tetramethylpiperidinyl-1-oxy (TEMPO) and a base as cocatalysts.

Identification of catalytically important residues of the carotenoid 1,2-hydratases from Rubrivivax gelatinosus and Thiocapsa roseopersicina.

Applied microbiology and biotechnology

Hiseni A, Otten LG, Arends IWCE.
PMID: 26481619
Appl Microbiol Biotechnol. 2016 Feb;100(3):1275-1284. doi: 10.1007/s00253-015-6998-y. Epub 2015 Oct 19.

Carotenoid 1,2-hydratases (CrtC) catalyze the selective addition of water to an isolated carbon-carbon double bond. Although their involvement in the carotenoid biosynthetic pathway is well understood, little is known about the mechanism by which these hydratases transform carotenoids such...

Nanoparticles of lanthanide oxysulfate/oxysulfide for improved oxygen storage/release.

Dalton transactions (Cambridge, England : 2003)

Zhang W, Arends IW, Djanashvili K.
PMID: 27515224
Dalton Trans. 2016 Sep 28;45(36):14019-22. doi: 10.1039/c6dt01667g. Epub 2016 Aug 12.

Lanthanide oxysulfates have the ability to store and release large volumes of oxygen under oxidizing/reducing conditions, rendering them interesting as automotive catalysts. Herein we demonstrate a remarkable improvement of both processes by utilization of nanoparticles compared to the bulk...

Showing 1 to 12 of 17 entries