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Showing 1 to 12 of 100 entries
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Post-infectious glomerulonephritis with crescents in adults: a retrospective study.

Clinical kidney journal

Baikunje S, Vankalakunti M, Nikith A, Srivatsa A, Alva S, Kamath J.
PMID: 26985372
Clin Kidney J. 2016 Apr;9(2):222-6. doi: 10.1093/ckj/sfv147. Epub 2016 Jan 20.

BACKGROUND: Crescent formation generally reflects severe glomerular injury. There is sparse literature on post-infectious glomerulonephritis (PIGN) with crescents in adults. This retrospective study looked at nine such cases to see if there is a correlation between the severity of...

Temporal dynamics of cerebral blood flow, cortical damage, apoptosis, astrocyte-vasculature interaction and astrogliosis in the pericontusional region after traumatic brain injury.

Frontiers in neurology

Villapol S, Byrnes KR, Symes AJ.
PMID: 24926283
Front Neurol. 2014 Jun 04;5:82. doi: 10.3389/fneur.2014.00082. eCollection 2014.

Traumatic brain injury (TBI) results in a loss of brain tissue at the moment of impact in the cerebral cortex. Subsequent secondary injury involves the release of molecular signals with dramatic consequences for the integrity of damaged tissue, leading...

Epigenetics in prostate cancer.

Prostate cancer

Albany C, Alva AS, Aparicio AM, Singal R, Yellapragada S, Sonpavde G, Hahn NM.
PMID: 22191037
Prostate Cancer. 2011;2011:580318. doi: 10.1155/2011/580318. Epub 2011 Nov 30.

Prostate cancer (PC) is the most commonly diagnosed nonskin malignancy and the second most common cause of cancer death among men in the United States. Epigenetics is the study of heritable changes in gene expression caused by mechanisms other...

Dynamic of Immune Response induced in Hepatitis B Surface Antigen-transgenic Mice Immunized with a Novel Therapeutic Formulation.

Euroasian journal of hepato-gastroenterology

Almeida FMF, Blanco A, Trujillo H, Hernández D, García D, Alba JS, Abad ML, Merino N, Lobaina Y, Aguilar Rubido JC.
PMID: 29201720
Euroasian J Hepatogastroenterol. 2016 Jan-Jun;6(1):25-30. doi: 10.5005/jp-journals-10018-1161. Epub 2016 Jul 09.

The development of therapeutic vaccines against chronic hepatitis B requires the capacity of the formulation to subvert a tolerated immune response as well as the evaluation of histopathological damage resulting from the treatment. In the present study, the dynamicity...

Rapid, ultra low coverage copy number profiling of cell-free DNA as a precision oncology screening strategy.

Oncotarget

Hovelson DH, Liu CJ, Wang Y, Kang Q, Henderson J, Gursky A, Brockman S, Ramnath N, Krauss JC, Talpaz M, Kandarpa M, Chugh R, Tuck M, Herman K, Grasso CS, Quist MJ, Feng FY, Haakenson C, Langmore J, Kamberov E, Tesmer T, Husain H, Lonigro RJ, Robinson D, Smith DC, Alva AS, Hussain MH, Chinnaiyan AM, Tewari M, Mills RE, Morgan TM, Tomlins SA.
PMID: 29163793
Oncotarget. 2017 Sep 22;8(52):89848-89866. doi: 10.18632/oncotarget.21163. eCollection 2017 Oct 27.

Current cell-free DNA (cfDNA) next generation sequencing (NGS) precision oncology workflows are typically limited to targeted and/or disease-specific applications. In advanced cancer, disease burden and cfDNA tumor content are often elevated, yielding unique precision oncology opportunities. We sought to...

Wearable Biomonitoring Platform for the Assessment of Stress and its Impact on Cognitive Performance of Firefighters: An Experimental Study.

Clinical practice and epidemiology in mental health : CP & EMH

Rodrigues S, Paiva JS, Dias D, Pimentel G, Kaiseler M, Cunha JPS.
PMID: 30972123
Clin Pract Epidemiol Ment Health. 2018 Oct 31;14:250-262. doi: 10.2174/1745017901814010250. eCollection 2018.

BACKGROUND: Stress is a complex process with an impact on health and performance. The use of wearable sensor-based monitoring systems offers interesting opportunities for advanced health care solutions for stress analysis. Considering the stressful nature of firefighting and its...

Stress among on-duty firefighters: an ambulatory assessment study.

PeerJ

Rodrigues S, Paiva JS, Dias D, Cunha JPS.
PMID: 30581658
PeerJ. 2018 Dec 11;6:e5967. doi: 10.7717/peerj.5967. eCollection 2018.

BACKGROUND: Stress at work has been broadly acknowledged as a worldwide problem and has been the focus of concern for many researchers. Firefighting, in particular, is frequently reported as a highly stressful occupation. In order to investigate firefighters' occupational...

Visible-Light-Driven Water Oxidation on Self-Assembled Metal-Free Organic@Carbon Junctions at Neutral pH.

JACS Au

Olaya AJ, Riva JS, Baster D, Silva WO, Pichard F, Girault HH.
PMID: 34977899
JACS Au. 2021 Nov 11;1(12):2294-2302. doi: 10.1021/jacsau.1c00408. eCollection 2021 Dec 27.

Sustainable water oxidation requires low-cost, stable, and efficient redox couples, photosensitizers, and catalysts. Here, we introduce the

'Let me move to another level': career advancement desires and opportunities for community health nurses in Ghana.

Global health promotion

Bellerose M, Awoonor-Williams K, Alva S, Magalona S, Sacks E.
PMID: 34269105
Glob Health Promot. 2021 Jul 16;17579759211027426. doi: 10.1177/17579759211027426. Epub 2021 Jul 16.

Career advancement and continued education are critical components of health worker motivation and retention. Continuous advancement also builds health system capacity by ensuring that leaders are those with experience and strong performance records. To understand more about the satisfaction,...

ATRX proximal protein associations boast roles beyond histone deposition.

PLoS genetics

Scott WA, Dhanji EZ, Dyakov BJA, Dreseris ES, Asa JS, Grange LJ, Mirceta M, Pearson CE, Stewart GS, Gingras AC, Campos EI.
PMID: 34780483
PLoS Genet. 2021 Nov 15;17(11):e1009909. doi: 10.1371/journal.pgen.1009909. eCollection 2021 Nov.

The ATRX ATP-dependent chromatin remodelling/helicase protein associates with the DAXX histone chaperone to deposit histone H3.3 over repetitive DNA regions. Because ATRX-protein interactions impart functions, such as histone deposition, we used proximity-dependent biotinylation (BioID) to identify proximal associations for...

Characterization of outcomes in patients with advanced genitourinary malignancies treated with immune checkpoint inhibitors.

Urologic oncology

Ma VT, Su CT, Hu M, Taylor JMG, Daignault-Newton S, Kellezi O, Dahl MN, Shah MA, Erickson S, Lora J, Hamasha R, Ali A, Yancey S, Kiros L, Balicki HM, Winfield DC, Green MD, Alva AS.
PMID: 33495117
Urol Oncol. 2021 Jul;39(7):437.e1-437.e9. doi: 10.1016/j.urolonc.2021.01.006. Epub 2021 Jan 23.

PURPOSE: Several immune checkpoint inhibitors (ICIs) are FDA approved for treatment of genitourinary (GU) malignancies. We aim to determine demographic and clinicopathologic characteristics that significantly affect clinical outcomes in patients with advanced stage GU malignancies treated with ICIs.MATERIALS AND...

Quality of TB services assessment: The unique contribution of patient and provider perspectives in identifying and addressing gaps in the quality of TB services.

Journal of clinical tuberculosis and other mycobacterial diseases

Colvin C, De Silva G, Garfin C, Alva S, Cloutier S, Gaviola D, Oyediran K, Rodrigo T, Chauffour J.
PMID: 31788559
J Clin Tuberc Other Mycobact Dis. 2019 Aug 21;17:100117. doi: 10.1016/j.jctube.2019.100117. eCollection 2019 Dec.

Ambitious efforts to detect and treat tuberculosis (TB) are required to reduce the burden of disease in low resource settings, and the provision of high quality TB services is critical to reaching global TB targets. The quality of TB...

Showing 1 to 12 of 100 entries