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Showing 1 to 12 of 234 entries
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Vaccine Potentiation by Combination Adjuvants.

Vaccines

Levast B, Awate S, Babiuk L, Mutwiri G, Gerdts V, van Drunen Littel-van den Hurk S.
PMID: 26344621
Vaccines (Basel). 2014 Apr 14;2(2):297-322. doi: 10.3390/vaccines2020297.

Adjuvants are crucial components of vaccines. They significantly improve vaccine efficacy by modulating, enhancing, or extending the immune response and at the same time reducing the amount of antigen needed. In contrast to previously licensed adjuvants, current successful adjuvant...

Getting Ready for the Dance: FANCJ Irons Out DNA Wrinkles.

Genes

Bharti SK, Awate S, Banerjee T, Brosh RM.
PMID: 27376332
Genes (Basel). 2016 Jul 01;7(7). doi: 10.3390/genes7070031.

Mounting evidence indicates that alternate DNA structures, which deviate from normal double helical DNA, form in vivo and influence cellular processes such as replication and transcription. However, our understanding of how the cellular machinery deals with unusual DNA structures...

Chemical Space: Big Data Challenge for Molecular Diversity.

Chimia

Awale M, Visini R, Probst D, Arús-Pous J, Reymond JL.
PMID: 29070411
Chimia (Aarau). 2017 Oct 25;71(10):661-666. doi: 10.2533/chimia.2017.661.

Chemical space describes all possible molecules as well as multi-dimensional conceptual spaces representing the structural diversity of these molecules. Part of this chemical space is available in public databases ranging from thousands to billions of compounds. Exploiting these databases...

Measurement of the thermoelectric power factor of films over the 10-400 K range.

The Review of scientific instruments

Hossain MA, Alaie S, Tehrani M.
PMID: 27131711
Rev Sci Instrum. 2016 Apr;87(4):045111. doi: 10.1063/1.4946997.

The design and development of a novel apparatus for the simultaneous measurement of electrical resistivity and Seebeck coefficient of films is reported here. Mounting stage is integrated inside a cryostat chamber enabling measurements over the 10-400 K temperature range,...

Clinico-Histopathological Spectrum of Infectious Granulomatous Dermatoses in Western India- A Representative Study from Mumbai.

Journal of clinical and diagnostic research : JCDR

Grover S, Agale SV, D'Costa GF, Valand AG, Gupta VK.
PMID: 27190811
J Clin Diagn Res. 2016 Apr;10(4):EC10-4. doi: 10.7860/JCDR/2016/16459.7568. Epub 2016 Apr 01.

INTRODUCTION: Infectious Granulomatous Dermatoses (IGDS) have various aetiological factors with a considerable overlap in the histopathological and clinical features, thus posing a diagnostic dilemma for dermatologists and pathologists.AIM: We aimed at determining the histopathological profile of IGDS correlating it...

Effects of Anethum graveolens L. (dill) on Oocyte and Fertility of Adult Female Rats.

Journal of reproduction & infertility

Monsefi M, Ghasemi A, Alaee S, Aliabadi E.
PMID: 25717430
J Reprod Infertil. 2015 Jan-Mar;16(1):10-7.

BACKGROUND: Our previous studies revealed Anethum graveolens L. caused some changes in female reproductive system that induced infertility. Therefore, in this study, oocyte changes as one of probable reasons of infertility were investigated.METHODS: In this study, 59 adult female...

A case of peripheral ameloblastoma of retromolar trigone: Histopathological and immunohistochemical profile.

Contemporary clinical dentistry

Surya V, Verma P, Amale K, Siwach P.
PMID: 26681867
Contemp Clin Dent. 2015 Oct-Dec;6(4):564-6. doi: 10.4103/0976-237X.169854.

Peripheral ameloblastoma (PA) is a rare and unusual entity with histological characteristics similar to those of the common intraosseous ameloblastoma. In this paper, we present a case of PA in a 44-year-old male affecting the right retromolar trigone area...

Expanding the fragrance chemical space for virtual screening.

Journal of cheminformatics

Ruddigkeit L, Awale M, Reymond JL.
PMID: 24876890
J Cheminform. 2014 May 22;6:27. doi: 10.1186/1758-2946-6-27. eCollection 2014.

The properties of fragrance molecules in the public databases SuperScent and Flavornet were analyzed to define a "fragrance-like" (FL) property range (Heavy Atom Count ≤ 21, only C, H, O, S, (O + S) ≤ 3, Hydrogen Bond Donor...

Tension arachnoid cyst with transtentorial herniation: A rare entity.

Neurology India

Balani A, Kumar AD, Marda SS, Alwala S.
PMID: 26448254
Neurol India. 2015 Sep-Oct;63(5):801-2. doi: 10.4103/0028-3886.166544.

No abstract available.

Prenylated Dihydrochalcones from Artocarpus altilis as Antiausterity Agents.

The Enzymes

Nguyen MT, Nguyen NT, Awale S.
PMID: 26298457
Enzymes. 2015;37:95-110. doi: 10.1016/bs.enz.2015.05.005. Epub 2015 Jun 24.

Human pancreatic cancer cell lines have remarkable tolerance to nutrition starvation, which enables them to survive under a tumor microenvironment. A novel antiausterity strategy in anticancer drug discovery led to the discovery of agents that preferentially inhibit the survival...

The polypharmacology browser: a web-based multi-fingerprint target prediction tool using ChEMBL bioactivity data.

Journal of cheminformatics

Awale M, Reymond JL.
PMID: 28270862
J Cheminform. 2017 Feb 21;9:11. doi: 10.1186/s13321-017-0199-x. eCollection 2017.

BACKGROUND: Several web-based tools have been reported recently which predict the possible targets of a small molecule by similarity to compounds of known bioactivity using molecular fingerprints (fps), however predictions in each case rely on similarities computed from only...

Photoinitiated polymerisation of monolithic stationary phases in polyimide coated capillaries using visible region LEDs.

Chemical communications (Cambridge, England)

Walsh Z, Abele S, Lawless B, Heger D, Klán P, Breadmore MC, Paull B, Macka M.
PMID: 19057760
Chem Commun (Camb). 2008 Dec 28;(48):6504-6. doi: 10.1039/b816958f. Epub 2008 Nov 07.

The spatially controlled synthesis of poly(glycidyl methacrylate-co-ethylene dimethacrylate) monolithic stationary phases in polyimide coated fused silica capillaries by visible light induced radical polymerisation using a three-component initiator and a 660 nm light emitting diode (LED) as a light source...

Showing 1 to 12 of 234 entries