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Showing 1 to 12 of 91 entries
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Role of medical journals in adverse drug reaction alerts.

Lancet (London, England)

Haramburu F, Begaud B, Pere JC, Marcel S, Albin H.
PMID: 2863560
Lancet. 1985 Sep 07;2(8454):550-1. doi: 10.1016/s0140-6736(85)90480-5.

No abstract available.

Proton irradiation: a key to the challenge of N-glycosidic bond formation in a prebiotic context.

Scientific reports

Saladino R, Bizzarri BM, Botta L, Šponer J, Šponer JE, Georgelin T, Jaber M, Rigaud B, Kapralov M, Timoshenko GN, Rozanov A, Krasavin E, Timperio AM, Mauro ED.
PMID: 29116184
Sci Rep. 2017 Nov 07;7(1):14709. doi: 10.1038/s41598-017-15392-8.

The formation of nucleosides in abiotic conditions is a major hurdle in origin-of-life studies. We have determined the pathway of a general reaction leading to the one-pot synthesis of ribo- and 2'-deoxy-ribonucleosides from sugars and purine nucleobases under proton...

EPA/DHA and Vitamin A Supplementation Improves Spatial Memory and Alleviates the Age-related Decrease in Hippocampal RXRγ and Kinase Expression in Rats.

Frontiers in aging neuroscience

Létondor A, Buaud B, Vaysse C, Richard E, Layé S, Pallet V, Alfos S.
PMID: 27242514
Front Aging Neurosci. 2016 May 09;8:103. doi: 10.3389/fnagi.2016.00103. eCollection 2016.

Studies suggest that eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and vitamin A are critical to delay aged-related cognitive decline. These nutrients regulate gene expression in the brain by binding to nuclear receptors such as the retinoid X receptors (RXRs)...

[Imputability of drug side effects].

La Nouvelle presse medicale

Dangoumau J, Begaud B.
PMID: 7145684
Nouv Presse Med. 1982 Oct 14;11(40):2995-7.

By imputability it is meant the assessment of the probable responsability of a drug in the development of undesirable effect. Its principle is based on the evaluation of some criteria derived from observation (intrinsic imputability) or relevant literature (extrinsic...

Weak temporal ratchet effect by asymmetric modulation of a laser.

Optics letters

Preda CE, Ségard B, Glorieux P.
PMID: 16832481
Opt Lett. 2006 Aug 01;31(15):2347-9. doi: 10.1364/ol.31.002347.

Subjecting lasers to triangular modulations of the pump produces phenomena that drastically depend on the symmetry of the triangle. For instance, with slow up-rising triangles, a laser below threshold on average may deliver coherent pulses, while it does not...

The role of pharmacoepidemiology in pharmacovigilance: a conference at the 6th ESOP Meeting, Budapest, 28 September 1998.

Pharmacoepidemiology and drug safety

Abenhaim L, Moore N, Bégaud B.
PMID: 15073881
Pharmacoepidemiol Drug Saf. 1999 Apr;8:S1-7. doi: 10.1002/(sici)1099-1557(199904)8:1+3.3.co;2-5.

No abstract available.

Towards high-valent uranium compounds from metallacyclic uranium(IV) precursors.

Chemical communications (Cambridge, England)

Bénaud O, Berthet JC, Thuéry P, Ephritikhine M.
PMID: 21766108
Chem Commun (Camb). 2011 Aug 28;47(32):9057-9. doi: 10.1039/c1cc13112e. Epub 2011 Jul 15.

Treatment of [NaUN*(C,N)(2)] [N* = N(SiMe(3))(2); C,N = CH(2)SiMe(2)N(SiMe(3))] with I(2) led to the formation of the larger metallacycle [UN*(N{SiMe(3)}SiMe(2)CH(2)CH(2)SiMe(2)N{SiMe(3)})I] resulting from U-C cleavage and C-C coupling. Reaction of [NaUN*(O,N)(2)] [O,N = OC(=CH(2))SiMe(2)N(SiMe(3))] with I(2) afforded the U(V) complex...

Recurrent bacteremia, a complication of cyanoacrylate injection for variceal bleeding: report of two cases and review of the literature.

Case reports in medicine

Galperine T, Flateau C, Venon MD, Lescure FX, Béraud G, Said Ibrahim T, Delisle F, Durand F, Faure K, Pialoux G, Guery B.
PMID: 19721702
Case Rep Med. 2009;2009:407053. doi: 10.1155/2009/407053. Epub 2009 Aug 16.

We report the first description of recurrent bacteremia in two patients after cyanoacrylate injection for gastric varices bleeding treated with antibiotics alone. Adapted and prolonged antibiotic treatment allowed a complete resolution of the infection with no relapse after more...

α-Synuclein Alters Toll-Like Receptor Expression.

Frontiers in neuroscience

Béraud D, Twomey M, Bloom B, Mittereder A, Ton V, Neitzke K, Chasovskikh S, Mhyre TR, Maguire-Zeiss KA.
PMID: 21747756
Front Neurosci. 2011 Jun 29;5:80. doi: 10.3389/fnins.2011.00080. eCollection 2011.

Parkinson's disease, an age-related neurodegenerative disorder, is characterized by the loss of dopamine neurons in the substantia nigra, the accumulation of α-synuclein in Lewy bodies and neurites, and neuroinflammation. While the exact etiology of sporadic Parkinson's disease remains elusive,...

Decrease in Fas-induced apoptosis by the γ-secretase inhibitor is dependent on p75(NTR) in a glioblastoma cell line.

Experimental and therapeutic medicine

Bessette B, Durand K, Giraud S, Bégaud G, Mathonnet M, Lalloué F.
PMID: 22969985
Exp Ther Med. 2012 May;3(5):873-877. doi: 10.3892/etm.2012.480. Epub 2012 Feb 13.

p75(NTR), a member of the tumor necrosis factor superfamily, plays a key role in numerous physiological processes, including cell survival or apoptosis. Yet, the associated signaling pathways remain poorly understood. Similar to Notch, γ-secretase cleavage is implicated in the...

A new durable pigment with hydrophobic surface based on natural nanotubes and indigo: Interactions and stability.

Journal of colloid and interface science

Zhuang G, Jaber M, Rodrigues F, Rigaud B, Walter P, Zhang Z.
PMID: 31129294
J Colloid Interface Sci. 2019 Sep 15;552:204-217. doi: 10.1016/j.jcis.2019.04.072. Epub 2019 Apr 24.

Covering with polyorganosilane (POS) was proved as an effective way to enhance the chemical and thermal stability of clay/dye hybrid pigments. But the photostability and interactions with clay minerals, dyes and POS layer has never been reported. In order...

Anticholinergic Activity of Psychotropic Drugs and Cognitive Impairment Among Participants Aged 45 and Over: The CONSTANCES Study.

Drug safety

Ziad A, Berr C, Ruiz F, Bégaud B, Lemogne C, Goldberg M, Zins M, Mura T.
PMID: 33575980
Drug Saf. 2021 May;44(5):565-579. doi: 10.1007/s40264-021-01043-5. Epub 2021 Feb 11.

INTRODUCTION: Psychotropic drugs such as anxiolytics, antidepressants and antipsychotics may have anticholinergic properties that could directly affect patients' cognition.OBJECTIVES: Our objective was to assess the relationship between exposure to anticholinergic-positive (AC+) psychotropic drugs and cognitive impairment compared with psychotropic...

Showing 1 to 12 of 91 entries