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Showing 1 to 12 of 176 entries
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Process relevant screening of cellulolytic organisms for consolidated bioprocessing.

Biotechnology for biofuels

Antonov E, Schlembach I, Regestein L, Rosenbaum MA, Büchs J.
PMID: 28450887
Biotechnol Biofuels. 2017 Apr 24;10:106. doi: 10.1186/s13068-017-0790-4. eCollection 2017.

BACKGROUND: Although the biocatalytic conversion of cellulosic biomass could replace fossil oil for the production of various compounds, it is often not economically viable due to the high costs of cellulolytic enzymes. One possibility to reduce costs is consolidated...

Stereocontrolled synthesis of 5-azaspiro[2.3]hexane derivatives as conformationally "frozen" analogues of L-glutamic acid.

Beilstein journal of organic chemistry

Bechi B, Amantini D, Tintori C, Botta M, Fabio Rd.
PMID: 24991261
Beilstein J Org Chem. 2014 May 14;10:1114-20. doi: 10.3762/bjoc.10.110. eCollection 2014.

Several strategies aimed to "freeze" natural amino acids into more constrained analogues have been developed with the aim of enhancing in vitro potency/selectivity and, more in general, drugability properties. The case of L-glutamic acid (L-Glu, 1) is of particular...

Quantitative proteomics reveals novel therapeutic and diagnostic markers in hypertension.

BBA clinical

Matafora V, Zagato L, Ferrandi M, Molinari I, Zerbini G, Casamassima N, Lanzani C, Delli Carpini S, Trepiccione F, Manunta P, Bachi A, Capasso G.
PMID: 26672470
BBA Clin. 2014 Oct 22;2:79-87. doi: 10.1016/j.bbacli.2014.10.001. eCollection 2014 Dec.

Hypertension is a prevalent disorder in the world representing one of the major risk factors for heart attack and stroke. These risks are increased in salt sensitive individuals. Hypertension and salt sensitivity are complex phenotypes whose pathophysiology remains poorly...

Efficient evaluation of cellulose digestibility by Trichoderma reesei Rut-C30 cultures in online monitored shake flasks.

Microbial cell factories

Antonov E, Wirth S, Gerlach T, Schlembach I, Rosenbaum MA, Regestein L, Büchs J.
PMID: 27686382
Microb Cell Fact. 2016 Sep 29;15(1):164. doi: 10.1186/s12934-016-0567-7.

BACKGROUND: Pretreated lignocellulosic biomass is considered as a suitable feedstock for the sustainable production of chemicals. However, the recalcitrant nature of cellulose often results in very cost-intensive overall production processes. A promising concept to reduce the costs is consolidated...

Aromatic ionene topology and counterion-tuned gelation of acidic aqueous solutions.

Soft matter

Bachl J, Bertran O, Mayr J, Alemán C, Díaz Díaz D.
PMID: 28374877
Soft Matter. 2017 Apr 19;13(16):3031-3041. doi: 10.1039/c7sm00234c.

Unusual gelation of acidic solutions was achieved using polycations bearing quaternary ammonium moieties. These ionene polymers are based on a disubstituted phenylene dibenzamide core, which allows the construction of different topomers (i.e. ortho-1, meta-2 and para-3). The topology of...

Streptokinase-administration in Myocardial Infarction Does Not Result in Cleavage of GPIb from the Platelet Surface as Measured by Circulating Glycocalicin Levels.

Platelets

Beer JH, Büchi L.
PMID: 21043640
Platelets. 1994;5(5):272-3. doi: 10.3109/09537109409006433.

No abstract available.

Technical administrative issues.

Veska

BACHI H.
PMID: 18098942
Veska. 1948 Nov;12(11):289-93.

No abstract available.

Perpendicular magnetic anisotropy, domains, and misfit strain in epitaxial Ni/Cu1-xNix/Cu/Si (001) thin films.

Physical review. B, Condensed matter

Ballentine CA, Bochi G, Güntherodt H, Hug HJ, Inglefield HE, Moser A, O'Handley RC, Stiefel B, Thompson CV.
PMID: 9979674
Phys Rev B Condens Matter. 1995 Sep 01;52(10):7311-7321. doi: 10.1103/physrevb.52.7311.

No abstract available.

Totally robotic intracorporeal side-to-side isoperistaltic strictureplasty for Crohn's disease.

Journal of minimal access surgery

Scaringi S, Giudici F, Zambonin D, Ficari F, Bechi P.
PMID: 29319021
J Minim Access Surg. 2018 Oct-Dec;14(4):341-344. doi: 10.4103/jmas.JMAS_212_17.

The development of bowel-sparing techniques (strictureplasties) for extended stricturing Crohn's disease (CD) and the increased use of minimally invasive surgery (wound sparing) represent the two most important improvements in inflammatory bowel disease surgery from the origin. Nevertheless, the minimally...

Online in vivo monitoring of cytosolic NAD redox dynamics in Ustilago maydis.

Biochimica et biophysica acta. Bioenergetics

Hartmann SK, Stockdreher Y, Wandrey G, Hosseinpour Tehrani H, Zambanini T, Meyer AJ, Büchs J, Blank LM, Schwarzländer M, Wierckx N.
PMID: 29800548
Biochim Biophys Acta Bioenerg. 2018 Oct;1859(10):1015-1024. doi: 10.1016/j.bbabio.2018.05.012. Epub 2018 May 22.

Maintenance of metabolic redox homeostasis is essential to all life and is a key factor in many biotechnological processes. Changes in the redox state of NAD affect metabolic fluxes, mediate regulation and signal transduction, and thus determine growth and...

Investigation of poly(γ-glutamic acid) production via online determination of viscosity and oxygen transfer rate in shake flasks.

Journal of biological engineering

Regestein Née Meissner L, Arndt J, Palmen TG, Jestel T, Mitsunaga H, Fukusaki E, Büchs J.
PMID: 28702080
J Biol Eng. 2017 Jul 12;11:23. doi: 10.1186/s13036-017-0065-4. eCollection 2017.

BACKGROUND: Poly(γ-glutamic acid) (γ-PGA) is a biopolymer with many useful properties making it applicable for instance in food and skin care industries, in wastewater treatment, in biodegradable plastics or in the pharmaceutical industry. γ-PGA is usually produced microbially by...

Promoters from the itaconate cluster of .

Fungal biology and biotechnology

Zambanini T, Hartmann SK, Schmitz LM, Büttner L, Hosseinpour Tehrani H, Geiser E, Beudels M, Venc D, Wandrey G, Büchs J, Schwarzländer M, Blank LM, Wierckx N.
PMID: 29209508
Fungal Biol Biotechnol. 2017 Nov 28;4:11. doi: 10.1186/s40694-017-0040-3. eCollection 2017.

RESULTS: Here we report on the investigation of two of the native promoters, P CONCLUSIONS: The promoters are well suited to induce gene expression in response to nitrogen limitation, coupled to the itaconate production phase, which contributes towards the...

Showing 1 to 12 of 176 entries