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Showing 1 to 12 of 73 entries
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Downregulation of IRS-1 in adipose tissue of offspring of obese mice is programmed cell-autonomously through post-transcriptional mechanisms.

Molecular metabolism

Fernandez-Twinn DS, Alfaradhi MZ, Martin-Gronert MS, Duque-Guimaraes DE, Piekarz A, Ferland-McCollough D, Bushell M, Ozanne SE.
PMID: 24749062
Mol Metab. 2014 Jan 20;3(3):325-33. doi: 10.1016/j.molmet.2014.01.007. eCollection 2014 Jun.

We determined the effects of maternal diet-induced obesity on offspring adipose tissue insulin signalling and miRNA expression in the aetiology of insulin resistance in later life. Although body composition and glucose tolerance of 8-week-old male offspring of obese dams...

Correction to Synthesis and Antineoplastic Evaluation of Novel Unsymmetrical 1,3,4-Oxadiazoles.

Journal of medicinal chemistry

Nieddu V, Pinna G, Marchesi I, Sanna L, Asproni B, Pinna GA, Bagella L, Murineddu G.
PMID: 28128556
J Med Chem. 2017 Feb 09;60(3):1226. doi: 10.1021/acs.jmedchem.7b00052. Epub 2017 Jan 27.

No abstract available.

Acoustic testing techniques for replicating in-flight dynamic loads.

The Journal of the Acoustical Society of America

Cohen KJ, Raveh DE.
PMID: 31153339
J Acoust Soc Am. 2019 May;145(5):2851. doi: 10.1121/1.5100280.

Modern weapon systems used on combat aircraft have complex electronic assemblies that are required to operate in a challenging dynamic environment throughout their life cycle. Among the various sources of excitation, aerodynamic noise is considered most significant. The paper...

Lung Thermal Ablation: Comparison between an Augmented Reality Computed Tomography (CT) 3D Navigation System (SIRIO) and Standard CT-Guided Technique.

Biology

Grasso RF, Andresciani F, Altomare C, Pacella G, Castiello G, Carassiti M, Quattrocchi CC, Faiella E, Beomonte Zobel B.
PMID: 34356501
Biology (Basel). 2021 Jul 11;10(7). doi: 10.3390/biology10070646.

(1) Background: The aim of this retrospective study is to assess safety and efficacy of lung radiofrequency (RFA) and microwave ablation (MWA) using an augmented reality computed tomography (CT) navigation system (SIRIO) and to compare it with the standard...

Thermodynamic and Biophysical Study of Fatty Acid Effector Binding to Soybean Lipoxygenase: Implications for Allostery Driven by Helix α2 Dynamics.

FEBS letters

Roberts DE, Benton AM, Fabian-Bayola C, Spuches AM, Offenbacher AR.
PMID: 34997975
FEBS Lett. 2022 Jan 08; doi: 10.1002/1873-3468.14275. Epub 2022 Jan 08.

Previous comparative kinetic isotope effects have inferred an allosteric site for fatty acids and their derivatives that modulates substrate selectivity in 15-lipoxygenases. Hydrogen-deuterium exchange also previously revealed regionally defined enhanced protein flexibility, centered at helix α2 - a gate...

From Model Organisms to Humans, the Opportunity for More Rigor in Methodologic and Statistical Analysis, Design, and Interpretation of Aging and Senescence Research.

The journals of gerontology. Series A, Biological sciences and medical sciences

Chusyd DE, Austad SN, Brown AW, Chen X, Dickinson SL, Ejima K, Fluharty D, Golzarri-Arroyo L, Holden R, Jamshidi-Naeini J, Landsittel D, Lartey S, Mannix E, Vorland CJ, Allison DB.
PMID: 34950945
J Gerontol A Biol Sci Med Sci. 2021 Dec 24; doi: 10.1093/gerona/glab382. Epub 2021 Dec 24.

This review identifies frequent design and analysis errors in aging and senescence research and discusses best practices in study design, statistical methods, analyses, and interpretation. Recommendations are offered for how to avoid these problems. The following issues are addressed:...

High Levels of Psychological Resilience Are Associated With Decreased Anxiety in Inflammatory Bowel Disease.

Inflammatory bowel diseases

Philippou A, Sehgal P, Ungaro RC, Wang K, Bagiella E, Dubinsky MC, Keefer L.
PMID: 34448855
Inflamm Bowel Dis. 2021 Aug 27; doi: 10.1093/ibd/izab200. Epub 2021 Aug 27.

BACKGROUND: Anxiety and depression are comorbid disorders with IBD and are associated with poor outcomes. Resilience is an innate but modifiable trait that may improve the symptoms of psychological disorders. Increasing resilience may decrease the severity of these comorbid...

3T MRI-Radiomic Approach to Predict for Lymph Node Status in Breast Cancer Patients.

Cancers

Santucci D, Faiella E, Cordelli E, Sicilia R, de Felice C, Zobel BB, Iannello G, Soda P.
PMID: 34066451
Cancers (Basel). 2021 May 06;13(9). doi: 10.3390/cancers13092228.

BACKGROUND: axillary lymph node (LN) status is one of the main breast cancer prognostic factors and it is currently defined by invasive procedures. The aim of this study is to predict LN metastasis combining MRI radiomics features with primary...

Rationale and Design of a Randomized Trial Evaluating an External Support Device for Saphenous Vein Coronary Grafts.

American heart journal

Bagiella E, Puskas JD, Moskowitz AJ, Gelijns AC, Alexander JH, Narula J, Smith PK, Hutcheson K, Chang HL, Gammie JS, Iribarne A, Marks ME, Vengrenyuk Y, Yasumura K, Raymond S, Taylor BS, Yarden O, Orion E, Dagenais F, Ailawadi G, Chu MWA, Gupta L, Levitan RG, Williams JB, Crestanello JA, Jessup M, Rose EA, Scavo V, Acker MA, Gillinov M, O'Gara PT, Voisine P, Mack MJ, Goldstein DJ.
PMID: 34936861
Am Heart J. 2021 Dec 19; doi: 10.1016/j.ahj.2021.12.009. Epub 2021 Dec 19.

BACKGROUND: Coronary artery bypass grafting (CABG) is the most common revascularization approach for the treatment of multi-vessel coronary artery disease. While the internal mammary artery is nearly universally used to bypass the left anterior descending coronary artery, autologous saphenous...

Clinical Characteristics of Hospitalized Covid-19 Patients in New York City.

medRxiv : the preprint server for health sciences

Paranjpe I, Russak AJ, De Freitas JK, Lala A, Miotto R, Vaid A, Johnson KW, Danieletto M, Golden E, Meyer D, Singh M, Somani S, Manna S, Nangia U, Kapoor A, O'Hagan R, O'Reilly PF, Huckins LM, Glowe P, Kia A, Timsina P, Freeman RM, Levin MA, Jhang J, Firpo A, Kovatch P, Finkelstein J, Aberg JA, Bagiella E, Horowitz CR, Murphy B, Fayad ZA, Narula J, Nestler EJ, Fuster V, Cordon-Cardo C, Charney DS, Reich DL, Just AC, Bottinger EP, Charney AW, Glicksberg BS, Nadkarni GN.
PMID: 32511655
medRxiv. 2020 Apr 26; doi: 10.1101/2020.04.19.20062117.

BACKGROUND: The coronavirus 2019 (Covid-19) pandemic is a global public health crisis, with over 1.6 million cases and 95,000 deaths worldwide. Data are needed regarding the clinical course of hospitalized patients, particularly in the United States.METHODS: Demographic, clinical, and...

Concomitant Tricuspid Repair in Patients with Degenerative Mitral Regurgitation.

The New England journal of medicine

Gammie JS, Chu MWA, Falk V, Overbey JR, Moskowitz AJ, Gillinov M, Mack MJ, Voisine P, Krane M, Yerokun B, Bowdish ME, Conradi L, Bolling SF, Miller MA, Taddei-Peters WC, Jeffries NO, Parides MK, Weisel R, Jessup M, Rose EA, Mullen JC, Raymond S, Moquete EG, O'Sullivan K, Marks ME, Iribarne A, Beyersdorf F, Borger MA, Geirsson A, Bagiella E, Hung J, Gelijns AC, O'Gara PT, Ailawadi G.
PMID: 34767705
N Engl J Med. 2021 Nov 13; doi: 10.1056/NEJMoa2115961. Epub 2021 Nov 13.

BACKGROUND: Tricuspid regurgitation is common in patients with severe degenerative mitral regurgitation. However, the evidence base is insufficient to inform a decision about whether to perform tricuspid-valve repair during mitral-valve surgery in patients who have moderate tricuspid regurgitation or...

Orientational distribution functions and order parameters in "de Vries"-type smectics: A simulation study.

The Journal of chemical physics

Jenz F, Osipov MA, Jagiella S, Giesselmann F.
PMID: 27782446
J Chem Phys. 2016 Oct 07;145(13):134901. doi: 10.1063/1.4963660.

Simple smectic A liquid crystal phases with different types of prescribed orientational distribution functions have been simulated and compared in order to study the possibility to distinguish between the Maier-Saupe type and cone-like orientational distributions using the popular method...

Showing 1 to 12 of 73 entries