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Showing 1 to 12 of 48 entries
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Bioabsorbable Bypass Grafts Biofunctionalised with RGD Have Enhanced Biophysical Properties and Endothelialisation Tested In vivo.

Frontiers in pharmacology

Antonova LV, Seifalian AM, Kutikhin AG, Sevostyanova VV, Krivkina EO, Mironov AV, Burago AY, Velikanova EA, Matveeva VG, Glushkova TV, Sergeeva EA, Vasyukov GY, Kudryavtseva YA, Barbarash OL, Barbarash LS.
PMID: 27252652
Front Pharmacol. 2016 May 25;7:136. doi: 10.3389/fphar.2016.00136. eCollection 2016.

Small diameter arterial bypass grafts are considered as unmet clinical need since the current grafts have poor patency of 25% within 5 years. We have developed a 3D scaffold manufactured from natural and synthetic biodegradable polymers, poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) and...

[Relationship Between Respiratory Function and Myocardial Structure and Function in Patients With Type 2 Diabetes Mellitus and Ischemic Heart Disease].

Kardiologiia

Bazdyrev ED, Bayrakova YV, Polikutina OM, Bezdenezhnykh NA, Slepynina YS, Barbarash OL.
PMID: 28294820
Kardiologiia. 2015 Jan;55(1):4-8.

PURPOSE: to analyze main parameters of respiratory dysfunction in patients with type 2 diabetes mellitus (DM) with and without concomitant ischemic heart disease (IHD).MATERIAL AND METHODS: We examined 104 patients with DM without (n= 64, 61.5%) and with (n=40,...

Leptin resistance: underlying mechanisms and diagnosis.

Diabetes, metabolic syndrome and obesity : targets and therapy

Gruzdeva O, Borodkina D, Uchasova E, Dyleva Y, Barbarash O.
PMID: 30774404
Diabetes Metab Syndr Obes. 2019 Jan 25;12:191-198. doi: 10.2147/DMSO.S182406. eCollection 2019.

Leptin and its receptors have been identified as key regulators of body weight and energy homeostasis. A decrease in tissue sensitivity to leptin leads to the development of obesity and metabolic disorders, such as insulin resistance and dyslipidemia. Mechanisms...

[The possibility of application of stimulant growth factor (ST2) for verifying postinfarction remodeling of myocardium.].

Klinicheskaia laboratornaia diagnostika

Dyleva YA, Gruzdeva OV, Akbasheva OE, Uchasova EG, Fedorova NV, Chernobai AG, Karetnikova VN, Kashtalap VV, Fedorova TS, Barbarash OL.
PMID: 31529921
Klin Lab Diagn. 2016;61(7):412-418. doi: 10.18821/0869-2084-2016-61-7-412-418.

PURPOSE OF STUDY: To detect level ST2 in blood serum of patients with myocardium infarction in dynamics of hospital period and their relationship with remodeling of myocardium.MATERIALS AND METHODS: The study sampling included 87 patients (65 males and 22...

A Technology for Anti-Thrombogenic Drug Coating of Small-Diameter Biodegradable Vascular Prostheses.

Sovremennye tekhnologii v meditsine

Antonova LV, Krivkina EO, Rezvova MA, Sevostyanova VV, Tkachenko VO, Glushkova TV, Akentyeva TN, Kudryavtseva YA, Barbarash LS.
PMID: 34796013
Sovrem Tekhnologii Med. 2021;12(6):6-12. doi: 10.17691/stm2020.12.6.01. Epub 2020 Dec 28.

MATERIALS AND METHODS: Vascular prostheses from polyhydroxybutyrate/valerate and polycaprolactone with the incorporated vascular endothelial growth factor, the main fibroblast growth factor, and the chemoattractant SDF-1α were made by emulsion electrospinning. Additional surface modification of the prostheses was carried out...

Immunological investigations

Ponasenko AV, Tsepokina AV, Khutornaya MV, Sinitsky MY, Barbarash OL.
PMID: 33522333
Immunol Invest. 2021 Feb 01;1-15. doi: 10.1080/08820139.2021.1876085. Epub 2021 Feb 01.

No abstract available.

Prognostic Model of Typical Complications Caused by Transcatheter Aortic Valve Replacement.

Sovremennye tekhnologii v meditsine

Ovcharenko EA, Klyshnikov KU, Ganyukov VI, Shilov AA, Vereshchagin IE, Sizova IN, Tarasov RS, Barbarash LS.
PMID: 34513050
Sovrem Tekhnologii Med. 2020;12(2):27-32. doi: 10.17691/stm2020.12.2.03.

MATERIALS AND METHODS: Clinical data of 10 patients implanted with CoreValveRESULTS: We observed significant positive changes in the severity of left ventricular myocardial hypertrophy; on the contrary, volume indicators did not significantly change, which might be associated with the...

Serum and Echocardiographic Markers May Synergistically Predict Adverse Cardiac Remodeling after ST-Segment Elevation Myocardial Infarction in Patients with Preserved Ejection Fraction.

Diagnostics (Basel, Switzerland)

Pecherina T, Kutikhin A, Kashtalap V, Karetnikova V, Gruzdeva O, Hryachkova O, Barbarash O.
PMID: 32423119
Diagnostics (Basel). 2020 May 14;10(5). doi: 10.3390/diagnostics10050301.

Improvement of risk scoring is particularly important for patients with preserved left ventricular ejection fraction (LVEF) who generally lack efficient monitoring of progressing heart failure. Here, we evaluated whether the combination of serum biomarkers and echocardiographic parameters may be...

bFGF and SDF-1α Improve In Vivo Performance of VEGF-Incorporating Small-Diameter Vascular Grafts.

Pharmaceuticals (Basel, Switzerland)

Antonova L, Kutikhin A, Sevostianova V, Velikanova E, Matveeva V, Glushkova T, Mironov A, Krivkina E, Shabaev A, Senokosova E, Barbarash L.
PMID: 33800631
Pharmaceuticals (Basel). 2021 Mar 28;14(4). doi: 10.3390/ph14040302.

Tissue-engineered vascular grafts are widely tested as a promising substitute for both arterial bypass and replacement surgery. We previously demonstrated that incorporation of VEGF into electrospun tubular scaffolds from poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/poly(ε-caprolactone) enhances formation of an endothelial cell monolayer. However, an...

Screening for Glucose Metabolism Disorders, Assessment the Disse Insulin Resistance Index and Hospital Prognosis of Coronary Artery Bypass Surgery.

Journal of personalized medicine

Sumin AN, Bezdenezhnykh NA, Bezdenezhnykh AV, Osokina AV, Kuz'mina AA, Tsepokina AV, Barbarash OL.
PMID: 34442446
J Pers Med. 2021 Aug 17;11(8). doi: 10.3390/jpm11080802.

OBJECTIVE: To study insulin resistance markers and their relationship with preoperative status and hospital complications of coronary artery bypass grafting (CABG) in patients with type 2 diabetes, prediabetes and normoglycemia.METHODS: We included 383 consecutive patients who underwent CABG. Patients...

[Efficacy of Behavioral Rehabilitation Programs in Patients With Myocardial Infarction. Dependence on the Type of Coronary Behavior].

Kardiologiia

Barbarash OL, Lebedeva NB, Zhukova EI, Tulchinskiĭ MI, Barbarash LS.
PMID: 12469108
Kardiologiia. 2001;41(12):73.

No abstract available.

Increased Serum Parathyroid Hormone, Osteocalcin and Alkaline Phosphatase Are Associated with a Long-Term Adverse Cardiovascular Outcome after Coronary Artery Bypass Graft Surgery.

Diagnostics (Basel, Switzerland)

Barbarash O, Zykov M, Kashtalap V, Hryachkova O, Kokov A, Gruzdeva O, Shibanova I, Kutikhin A.
PMID: 31597282
Diagnostics (Basel). 2019 Oct 08;9(4). doi: 10.3390/diagnostics9040143.

Despite the fact that an association of osteopoenia/osteoporosis with elevated risk of coronary artery calcification (CAC) and coronary atherosclerosis (CA) is well-established, it remains unclear whether bone turnover markers can be employed in long-term prognostication of such patients. Here...

Showing 1 to 12 of 48 entries