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Antonova LV, Seifalian AM, Kutikhin AG, et al. Bioabsorbable Bypass Grafts Biofunctionalised with RGD Have Enhanced Biophysical Properties and Endothelialisation Tested In vivo. Front Pharmacol. 2016;7:136doi: 10.3389/fphar.2016.00136.
Antonova, L. V., Seifalian, A. M., Kutikhin, A. G., Sevostyanova, V. V., Krivkina, E. O., Mironov, A. V., Burago, A. Y., Velikanova, E. A., Matveeva, V. G., Glushkova, T. V., Sergeeva, E. A., Vasyukov, G. Y., Kudryavtseva, Y. A., Barbarash, O. L., & Barbarash, L. S. (2016). Bioabsorbable Bypass Grafts Biofunctionalised with RGD Have Enhanced Biophysical Properties and Endothelialisation Tested In vivo. Frontiers in pharmacology, 7136. https://doi.org/10.3389/fphar.2016.00136
Antonova, Larisa V, et al. "Bioabsorbable Bypass Grafts Biofunctionalised with RGD Have Enhanced Biophysical Properties and Endothelialisation Tested In vivo." Frontiers in pharmacology vol. 7 (2016): 136. doi: https://doi.org/10.3389/fphar.2016.00136
Antonova LV, Seifalian AM, Kutikhin AG, Sevostyanova VV, Krivkina EO, Mironov AV, Burago AY, Velikanova EA, Matveeva VG, Glushkova TV, Sergeeva EA, Vasyukov GY, Kudryavtseva YA, Barbarash OL, Barbarash LS. Bioabsorbable Bypass Grafts Biofunctionalised with RGD Have Enhanced Biophysical Properties and Endothelialisation Tested In vivo. Front Pharmacol. 2016 May 25;7:136. doi: 10.3389/fphar.2016.00136. eCollection 2016. PMID: 27252652; PMCID: PMC4879758.
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Front Pharmacol. 2016 May 25;7:136. doi: 10.3389/fphar.2016.00136. eCollection 2016.

Bioabsorbable Bypass Grafts Biofunctionalised with RGD Have Enhanced Biophysical Properties and Endothelialisation Tested In vivo.

Frontiers in pharmacology

Larisa V Antonova, Alexander M Seifalian, Anton G Kutikhin, Victoria V Sevostyanova, Evgeniya O Krivkina, Andrey V Mironov, Andrey Y Burago, Elena A Velikanova, Vera G Matveeva, Tatiana V Glushkova, Evgeniya A Sergeeva, Georgiy Y Vasyukov, Yuliya A Kudryavtseva, Olga L Barbarash, Leonid S Barbarash

Affiliations

  1. Research Institute for Complex Issues of Cardiovascular Diseases Kemerovo, Russia.
  2. Centre for Nanotechnology and Regenerative Medicine, UCL Division of Surgery and Interventional Science, University College LondonLondon, UK; NanoRegMed LtdLondon, UK.

PMID: 27252652 PMCID: PMC4879758 DOI: 10.3389/fphar.2016.00136

Abstract

Small diameter arterial bypass grafts are considered as unmet clinical need since the current grafts have poor patency of 25% within 5 years. We have developed a 3D scaffold manufactured from natural and synthetic biodegradable polymers, poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) and poly(

Keywords: RGD peptides; biocompatibility; endothelialisation; morphology; physico-mechanical properties; poly(3-hydroxybutyrate-co-3-hydroxyvalerate); poly(; vascular grafts

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