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Showing 1 to 12 of 12 entries
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Bioabsorbable Bypass Grafts Biofunctionalised with RGD Have Enhanced Biophysical Properties and Endothelialisation Tested In vivo.

Frontiers in pharmacology

Antonova LV, Seifalian AM, Kutikhin AG, Sevostyanova VV, Krivkina EO, Mironov AV, Burago AY, Velikanova EA, Matveeva VG, Glushkova TV, Sergeeva EA, Vasyukov GY, Kudryavtseva YA, Barbarash OL, Barbarash LS.
PMID: 27252652
Front Pharmacol. 2016 May 25;7:136. doi: 10.3389/fphar.2016.00136. eCollection 2016.

Small diameter arterial bypass grafts are considered as unmet clinical need since the current grafts have poor patency of 25% within 5 years. We have developed a 3D scaffold manufactured from natural and synthetic biodegradable polymers, poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) and...

[A facile method for producing selenocysteine-containing proteins].

Angewandte Chemie (Weinheim an der Bergstrasse, Germany)

Mukai T, Sevostyanova A, Suzuki T, Fu X, Söll D.
PMID: 30002564
Angew Chem Weinheim Bergstr Ger. 2018 Jun 11;130(24):7333-7337. Epub 2018 Apr 06.

No abstract available.

A Technology for Anti-Thrombogenic Drug Coating of Small-Diameter Biodegradable Vascular Prostheses.

Sovremennye tekhnologii v meditsine

Antonova LV, Krivkina EO, Rezvova MA, Sevostyanova VV, Tkachenko VO, Glushkova TV, Akentyeva TN, Kudryavtseva YA, Barbarash LS.
PMID: 34796013
Sovrem Tekhnologii Med. 2021;12(6):6-12. doi: 10.17691/stm2020.12.6.01. Epub 2020 Dec 28.

MATERIALS AND METHODS: Vascular prostheses from polyhydroxybutyrate/valerate and polycaprolactone with the incorporated vascular endothelial growth factor, the main fibroblast growth factor, and the chemoattractant SDF-1α were made by emulsion electrospinning. Additional surface modification of the prostheses was carried out...

bFGF and SDF-1α Improve In Vivo Performance of VEGF-Incorporating Small-Diameter Vascular Grafts.

Pharmaceuticals (Basel, Switzerland)

Antonova L, Kutikhin A, Sevostianova V, Velikanova E, Matveeva V, Glushkova T, Mironov A, Krivkina E, Shabaev A, Senokosova E, Barbarash L.
PMID: 33800631
Pharmaceuticals (Basel). 2021 Mar 28;14(4). doi: 10.3390/ph14040302.

Tissue-engineered vascular grafts are widely tested as a promising substitute for both arterial bypass and replacement surgery. We previously demonstrated that incorporation of VEGF into electrospun tubular scaffolds from poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/poly(ε-caprolactone) enhances formation of an endothelial cell monolayer. However, an...

Thyroid disorders and pathospermia in the ART clinic patients.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology

Lisovskaya TV, Dubrovina OS, Treshchilov IM, Senturina LB, Sevostyanova OY, Mayasina EN, Buev YE, Salimov DF.
PMID: 34937506
Gynecol Endocrinol. 2021;37:4-7. doi: 10.1080/09513590.2021.2006439.

OBJECTIVE: Over the past decade, a decrease in the semen quality in men of reproductive age, along with an increase in the incidence of thyroid diseases among young patients have been clearly noticed. The study was designed to determine...

Modification of Glyceraldehyde-3-Phosphate Dehydrogenase with Nitric Oxide: Role in Signal Transduction and Development of Apoptosis.

Biomolecules

Muronetz VI, Medvedeva MV, Sevostyanova IA, Schmalhausen EV.
PMID: 34827652
Biomolecules. 2021 Nov 08;11(11). doi: 10.3390/biom11111656.

This review focuses on the consequences of GAPDH

Modification of Glyceraldehyde-3-Phosphate Dehydrogenase with Nitric Oxide: Role in Signal Transduction and Development of Apoptosis.

Biomolecules

Muronetz VI, Medvedeva MV, Sevostyanova IA, Schmalhausen EV.
PMID: 34827652
Biomolecules. 2021 Nov 08;11(11). doi: 10.3390/biom11111656.

This review focuses on the consequences of GAPDH

Vascular Endothelial Growth Factor Improves Physico-Mechanical Properties and Enhances Endothelialization of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/Poly(ε-caprolactone) Small-Diameter Vascular Grafts In vivo.

Frontiers in pharmacology

Antonova LV, Sevostyanova VV, Kutikhin AG, Mironov AV, Krivkina EO, Shabaev AR, Matveeva VG, Velikanova EA, Sergeeva EA, Burago AY, Vasyukov GY, Glushkova TV, Kudryavtseva YA, Barbarash OL, Barbarash LS.
PMID: 27524968
Front Pharmacol. 2016 Jul 29;7:230. doi: 10.3389/fphar.2016.00230. eCollection 2016.

The combination of a natural polymer poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) and a synthetic hydrophobic polymer poly(ε-caprolactone) (PCL) is promising for the preparation of biodegradable and biocompatible small-diameter vascular grafts for bypass surgery. However, physico-mechanical properties and endothelialization rate of PHBV/PCL grafts...

[The software for jam-resistant sampling of analog EEG records on paper].

Meditsinskaia tekhnika

Ivanov KO, Sevastyanov VV, Furman YA.
PMID: 25980217
Med Tekh. 2015 Jan-Feb;(1):30-2.

No abstract available.

Biodegradable Patches for Arterial Reconstruction Modified with RGD Peptides: Results of an Experimental Study.

ACS omega

Sevostianova VV, Antonova LV, Mironov AV, Yuzhalin AE, Silnikov VN, Glushkova TV, Godovikova TS, Krivkina EO, Bolbasov E, Akentyeva TN, Khanova MY, Matveeva VG, Velikanova EA, Tarasov RS, Barbarash LS.
PMID: 32905385
ACS Omega. 2020 Aug 19;5(34):21700-21711. doi: 10.1021/acsomega.0c02593. eCollection 2020 Sep 01.

Modification by Arg-Gly-Asp (RGD) peptides is a promising approach to improve the biocompatibility of biodegradable vascular patches for arteriotomy. In this study, we evaluated the performance of vascular patches electrospun using a blend of polycaprolactone (PCL) and polyhydroxybutyrate/valerate (PHBV)...

Biocompatibility of Small-Diameter Vascular Grafts in Different Modes of RGD Modification.

Polymers

Antonova LV, Silnikov VN, Sevostyanova VV, Yuzhalin AE, Koroleva LS, Velikanova EA, Mironov AV, Godovikova TS, Kutikhin AG, Glushkova TV, Serpokrylova IY, Senokosova EA, Matveeva VG, Khanova MY, Akentyeva TN, Krivkina EO, Kudryavtseva YA, Barbarash LS.
PMID: 30960158
Polymers (Basel). 2019 Jan 18;11(1). doi: 10.3390/polym11010174.

Modification with Arg-Gly-Asp (RGD) peptides is a promising approach to improve biocompatibility of small-calibre vascular grafts but it is unknown how different RGD sequence composition impacts graft performance. Here we manufactured 1.5 mm poly(3-hydroxybutyrate-

Tissue-Engineered Carotid Artery Interposition Grafts Demonstrate High Primary Patency and Promote Vascular Tissue Regeneration in the Ovine Model.

Polymers

Antonova LV, Krivkina EO, Sevostianova VV, Mironov AV, Rezvova MA, Shabaev AR, Tkachenko VO, Krutitskiy SS, Khanova MY, Sergeeva TY, Matveeva VG, Glushkova TV, Kutikhin AG, Mukhamadiyarov RA, Deeva NS, Akentieva TN, Sinitsky MY, Velikanova EA, Barbarash LS.
PMID: 34451177
Polymers (Basel). 2021 Aug 08;13(16). doi: 10.3390/polym13162637.

Tissue-engineered vascular graft for the reconstruction of small arteries is still an unmet clinical need, despite the fact that a number of promising prototypes have entered preclinical development. Here we test Poly(3-hydroxybutyrate-co-3-hydroxyvalerate)Poly(ε-caprolactone) 4-mm-diameter vascular grafts equipped with vascular endothelial...

Showing 1 to 12 of 12 entries