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Showing 1 to 12 of 15 entries
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Bioabsorbable Bypass Grafts Biofunctionalised with RGD Have Enhanced Biophysical Properties and Endothelialisation Tested In vivo.

Frontiers in pharmacology

Antonova LV, Seifalian AM, Kutikhin AG, Sevostyanova VV, Krivkina EO, Mironov AV, Burago AY, Velikanova EA, Matveeva VG, Glushkova TV, Sergeeva EA, Vasyukov GY, Kudryavtseva YA, Barbarash OL, Barbarash LS.
PMID: 27252652
Front Pharmacol. 2016 May 25;7:136. doi: 10.3389/fphar.2016.00136. eCollection 2016.

Small diameter arterial bypass grafts are considered as unmet clinical need since the current grafts have poor patency of 25% within 5 years. We have developed a 3D scaffold manufactured from natural and synthetic biodegradable polymers, poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) and...

Two metagenomes from late pleistocene northeast siberian permafrost.

Genome announcements

Krivushin K, Kondrashov F, Shmakova L, Tutukina M, Petrovskaya L, Rivkina E.
PMID: 25555741
Genome Announc. 2015 Jan 02;3(1). doi: 10.1128/genomeA.01380-14.

The present study reports metagenomic shotgun sequencing of microbial communities of two ancient permafrost horizons of the Russian Arctic. Results demonstrate a significant difference in microbial community structure of the analyzed samples in general and microorganisms of the methane...

Draft Genome Sequence of Microbacterium sp. Gd 4-13, Isolated from Gydanskiy Peninsula Permafrost Sediments of Marine Origin.

Microbiology resource announcements

Spirina EV, Kuleshov KV, Yunusova AK, Vishnivetskaya TA, Rivkina EM.
PMID: 31582456
Microbiol Resour Announc. 2019 Oct 03;8(40). doi: 10.1128/MRA.00889-19.

Here, we report the draft genome sequence of

Metagenomes from Late Pleistocene Ice Complex Sediments of the Siberian Arctic.

Microbiology resource announcements

Vishnivetskaya T, Spirina E, Shmakova L, Tutukina M, Li Z, Wu X, Rivkina E.
PMID: 31649080
Microbiol Resour Announc. 2019 Oct 24;8(43). doi: 10.1128/MRA.01010-19.

The late Pleistocene Ice Complex (also known as Yedoma) encompasses ice-rich permafrost formed when alluvial and/or aeolian sediments accumulated under cold climatic conditions. Three metagenomes obtained from Yedoma deposits continually frozen for periods up to 60,000 years are reported...

A Technology for Anti-Thrombogenic Drug Coating of Small-Diameter Biodegradable Vascular Prostheses.

Sovremennye tekhnologii v meditsine

Antonova LV, Krivkina EO, Rezvova MA, Sevostyanova VV, Tkachenko VO, Glushkova TV, Akentyeva TN, Kudryavtseva YA, Barbarash LS.
PMID: 34796013
Sovrem Tekhnologii Med. 2021;12(6):6-12. doi: 10.17691/stm2020.12.6.01. Epub 2020 Dec 28.

MATERIALS AND METHODS: Vascular prostheses from polyhydroxybutyrate/valerate and polycaprolactone with the incorporated vascular endothelial growth factor, the main fibroblast growth factor, and the chemoattractant SDF-1α were made by emulsion electrospinning. Additional surface modification of the prostheses was carried out...

Draft Genome Sequence of Antarctic Methanogen Enriched from Dry Valley Permafrost.

Genome announcements

Buongiorno J, Bird JT, Krivushin K, Oshurkova V, Shcherbakova V, Rivkina EM, Lloyd KG, Vishnivetskaya TA.
PMID: 27932654
Genome Announc. 2016 Dec 08;4(6). doi: 10.1128/genomeA.01362-16.

A genomic reconstruction belonging to the genus Methanosarcina was assembled from metagenomic data from a methane-producing enrichment of Antarctic permafrost. This is the first methanogen genome reported from permafrost of the Dry Valleys and can help shed light on...

bFGF and SDF-1α Improve In Vivo Performance of VEGF-Incorporating Small-Diameter Vascular Grafts.

Pharmaceuticals (Basel, Switzerland)

Antonova L, Kutikhin A, Sevostianova V, Velikanova E, Matveeva V, Glushkova T, Mironov A, Krivkina E, Shabaev A, Senokosova E, Barbarash L.
PMID: 33800631
Pharmaceuticals (Basel). 2021 Mar 28;14(4). doi: 10.3390/ph14040302.

Tissue-engineered vascular grafts are widely tested as a promising substitute for both arterial bypass and replacement surgery. We previously demonstrated that incorporation of VEGF into electrospun tubular scaffolds from poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/poly(ε-caprolactone) enhances formation of an endothelial cell monolayer. However, an...

A living bdelloid rotifer from 24,000-year-old Arctic permafrost.

Current biology : CB

Shmakova L, Malavin S, Iakovenko N, Vishnivetskaya T, Shain D, Plewka M, Rivkina E.
PMID: 34102116
Curr Biol. 2021 Jun 07;31(11):R712-R713. doi: 10.1016/j.cub.2021.04.077.

In natural, permanently frozen habitats, some organisms may be preserved for hundreds to tens of thousands of years. For example, stems of Antarctic moss were successfully regrown from an over millennium-old sample covered by ice for about 400 years

Frozen Zoo: a collection of permafrost samples containing viable protists and their viruses.

Biodiversity data journal

Malavin S, Shmakova L, Claverie JM, Rivkina E.
PMID: 32733138
Biodivers Data J. 2020 Jul 10;8:e51586. doi: 10.3897/BDJ.8.e51586. eCollection 2020.

BACKGROUND: Permafrost, frozen ground cemented with ice, occupies about a quarter of the Earth's hard surface and reaches up to 1000 metres depth. Due to constant subzero temperatures, permafrost represents a unique record of past epochs, whenever it comes...

Calciprotein Particles Link Disturbed Mineral Homeostasis with Cardiovascular Disease by Causing Endothelial Dysfunction and Vascular Inflammation.

International journal of molecular sciences

Shishkova DK, Velikanova EA, Bogdanov LA, Sinitsky MY, Kostyunin AE, Tsepokina AV, Gruzdeva OV, Mironov AV, Mukhamadiyarov RA, Glushkova TV, Krivkina EO, Matveeva VG, Hryachkova ON, Markova VE, Dyleva YA, Belik EV, Frolov AV, Shabaev AR, Efimova OS, Popova AN, Malysheva VY, Kolmykov RP, Sevostyanov OG, Russakov DM, Dolganyuk VF, Gutakovsky AK, Zhivodkov YA, Kozhukhov AS, Brusina EB, Ismagilov ZR, Barbarash OL, Yuzhalin AE, Kutikhin AG.
PMID: 34830334
Int J Mol Sci. 2021 Nov 18;22(22). doi: 10.3390/ijms222212458.

An association between high serum calcium/phosphate and cardiovascular events or death is well-established. However, a mechanistic explanation of this correlation is lacking. Here, we examined the role of calciprotein particles (CPPs), nanoscale bodies forming in the human blood upon...

Vascular Endothelial Growth Factor Improves Physico-Mechanical Properties and Enhances Endothelialization of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/Poly(ε-caprolactone) Small-Diameter Vascular Grafts In vivo.

Frontiers in pharmacology

Antonova LV, Sevostyanova VV, Kutikhin AG, Mironov AV, Krivkina EO, Shabaev AR, Matveeva VG, Velikanova EA, Sergeeva EA, Burago AY, Vasyukov GY, Glushkova TV, Kudryavtseva YA, Barbarash OL, Barbarash LS.
PMID: 27524968
Front Pharmacol. 2016 Jul 29;7:230. doi: 10.3389/fphar.2016.00230. eCollection 2016.

The combination of a natural polymer poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) and a synthetic hydrophobic polymer poly(ε-caprolactone) (PCL) is promising for the preparation of biodegradable and biocompatible small-diameter vascular grafts for bypass surgery. However, physico-mechanical properties and endothelialization rate of PHBV/PCL grafts...

Biodegradable Patches for Arterial Reconstruction Modified with RGD Peptides: Results of an Experimental Study.

ACS omega

Sevostianova VV, Antonova LV, Mironov AV, Yuzhalin AE, Silnikov VN, Glushkova TV, Godovikova TS, Krivkina EO, Bolbasov E, Akentyeva TN, Khanova MY, Matveeva VG, Velikanova EA, Tarasov RS, Barbarash LS.
PMID: 32905385
ACS Omega. 2020 Aug 19;5(34):21700-21711. doi: 10.1021/acsomega.0c02593. eCollection 2020 Sep 01.

Modification by Arg-Gly-Asp (RGD) peptides is a promising approach to improve the biocompatibility of biodegradable vascular patches for arteriotomy. In this study, we evaluated the performance of vascular patches electrospun using a blend of polycaprolactone (PCL) and polyhydroxybutyrate/valerate (PHBV)...

Showing 1 to 12 of 15 entries