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Showing 1 to 12 of 284 entries
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Photonic non-contact estimation of blood lactate level.

Biomedical optics express

Abraham C, Beiderman Y, Ozana N, Tenner F, Schmidt M, Sanz M, Garcia J, Zalevsky Z.
PMID: 26504661
Biomed Opt Express. 2015 Sep 28;6(10):4144-53. doi: 10.1364/BOE.6.004144. eCollection 2015 Oct 01.

The ability to measure the blood lactate level in a non-invasive, non-contact manner is very appealing to the sports industry as well as the home care field. That is mainly because this substance level is an imperative parameter in...

Rapid Synthesis of Boc-2',6'-dimethyl-l-tyrosine and Derivatives and Incorporation into Opioid Peptidomimetics.

ACS medicinal chemistry letters

Bender AM, Griggs NW, Gao C, Trask TJ, Traynor JR, Mosberg HI.
PMID: 26713104
ACS Med Chem Lett. 2015 Oct 19;6(12):1199-203. doi: 10.1021/acsmedchemlett.5b00344. eCollection 2015 Dec 10.

The unnatural amino acid 2',6'-dimethyl-l-tyrosine has found widespread use in the development of synthetic opioid ligands. Opioids featuring this residue at the N-terminus often display superior potency at one or more of the opioid receptor types, but the availability...

Metrabase: a cheminformatics and bioinformatics database for small molecule transporter data analysis and (Q)SAR modeling.

Journal of cheminformatics

Mak L, Marcus D, Howlett A, Yarova G, Duchateau G, Klaffke W, Bender A, Glen RC.
PMID: 26106450
J Cheminform. 2015 Jun 23;7:31. doi: 10.1186/s13321-015-0083-5. eCollection 2015.

ABSTRACT: Both metabolism and transport are key elements defining the bioavailability and biological activity of molecules, i.e. their adverse and therapeutic effects. Structured and high quality experimental data stored in a suitable container, such as a relational database, facilitates...

Are phylogenetic trees suitable for chemogenomics analyses of bioactivity data sets: the importance of shared active compounds and choosing a suitable data embedding method, as exemplified on Kinases.

Journal of cheminformatics

Paricharak S, Klenka T, Augustin M, Patel UA, Bender A.
PMID: 24330772
J Cheminform. 2013 Dec 13;5(1):49. doi: 10.1186/1758-2946-5-49.

BACKGROUND: 'Phylogenetic trees' are commonly used for the analysis of chemogenomics datasets and to relate protein targets to each other, based on the (shared) bioactivities of their ligands. However, no real assessment as to the suitability of this representation...

American Thoracic Society and National Heart, Lung, and Blood Institute Implementation Research Workshop Report.

Annals of the American Thoracic Society

Bender BG, Krishnan JA, Chambers DA, Cloutier MM, Riekert KA, Rand CS, Schatz M, Thomson CC, Wilson SR, Apter A, Carson SS, George M, Gerald JK, Gerald L, Goss CH, Okelo SO, Mularski RA, Nguyen HQ, Patel MR, Szefler SJ, Weiss CH, Wilson KC, Freemer M.
PMID: 26653201
Ann Am Thorac Soc. 2015 Dec;12(12):S213-21. doi: 10.1513/AnnalsATS.201506-367OT.

To advance implementation research (IR) in respiratory, sleep, and critical care medicine, the American Thoracic Society and the Division of Lung Diseases from the NHLBI cosponsored an Implementation Research Workshop on May 17, 2014. The goals of IR are...

Cheminformatics Research at the Unilever Centre for Molecular Science Informatics Cambridge.

Molecular informatics

Fuchs JE, Bender A, Glen RC.
PMID: 26435758
Mol Inform. 2015 Sep;34(9):626-633. doi: 10.1002/minf.201400166. Epub 2015 Mar 10.

The Centre for Molecular Informatics, formerly Unilever Centre for Molecular Science Informatics (UCMSI), at the University of Cambridge is a world-leading driving force in the field of cheminformatics. Since its opening in 2000 more than 300 scientific articles have...

Utility of computed tomographic enteroclysis for the general surgeon(1).

Current surgery

Arciero CA, Bender GN, Shriver CD.
PMID: 11275247
Curr Surg. 2001 Mar;58(2):205-208. doi: 10.1016/s0149-7944(00)00454-2.

Enteroclysis uses contrast fluid distention of the small bowel through a jejunal catheter with flouroscopic imaging to identify abnormalities. Computed tomograpic enteroclysis (CT-E) adds cross-sectional imaging to identify small bowel pathology to include masses, gastrointestinal bleeding of unknown origin,...

Harvesting chemical information from the Internet using a distributed approach: ChemXtreme.

Journal of chemical information and modeling

Karthikeyan M, Krishnan S, Pandey AK, Bender A.
PMID: 16562972
J Chem Inf Model. 2006 Mar-Apr;46(2):452-61. doi: 10.1021/ci050329+.

The Internet is a comprehensive resource of chemical information which is at the same time largely unstructured. It provides a wealth of scientific information such as experimental data and requires a suitable automated data mining and analysis tool for...

Similarity between Copper Resistance Genes from Xanthomonas campestris and Pseudomonas syringae.

Applied and environmental microbiology

Voloudakis AE, Bender CL, Cooksey DA.
PMID: 16348942
Appl Environ Microbiol. 1993 May;59(5):1627-34. doi: 10.1128/aem.59.5.1627-1634.1993.

Plasmid-borne copper resistance genes from copper-resistant strains of Xanthomonas campestris pv. vesicatoria from California, Florida, and Oklahoma shared structural similarities. A strain of X. campestris pv. campestris also contained plasmid-borne copper resistance genes similar to the resistance genes from...

A role for chloroplast-localized Thylakoid Formation 1 (THF1) in bacterial speck disease development.

Plant signaling & behavior

Wangdi T, Uppalapati SR, Nagaraj S, Ryu CM, Bender CL, Mysore KS.
PMID: 20339321
Plant Signal Behav. 2010 Apr;5(4):425-7. doi: 10.4161/psb.5.4.11284. Epub 2010 Apr 20.

Coronatine (COR), a jasmonate mimic produced by Pseudomonas syringae pv. tomato DC3000 (Pst DC3000) is required for full virulence of Pst DC3000 in tomato and Arabidopsis. COR is shown to induce a range of physiological processes including chlorosis, root...

Neurotoxicity of NMDA antagonists: a glutamatergic theory of schizophrenia based on selective impairment of local inhibitory feedback circuits.

Dialogues in clinical neuroscience

Grunze H, Bender A, Wendhof S, Schäfer M, Rujescu D.
PMID: 22033472
Dialogues Clin Neurosci. 2000 Sep;2(3):287-98.

Modulation of recurrent inhibition is critical not only for the normal function of highly excitable regions of the brain, especially the limbic system, but may also be a primary determining factor for the viability of neurons in these regions....

Anger elicitation in tonga and Germany: the impact of culture on cognitive determinants of emotions.

Frontiers in psychology

Bender A, Spada H, Rothe-Wulf A, Traber S, Rauss K.
PMID: 23112780
Front Psychol. 2012 Oct 25;3:435. doi: 10.3389/fpsyg.2012.00435. eCollection 2012.

The cognitive appraisal of an event is crucial for the elicitation and differentiation of emotions, and causal attributions are an integral part of this process. In an interdisciplinary project comparing Tonga and Germany, we examined how cultural differences in...

Showing 1 to 12 of 284 entries