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Design, development and characterization of ACT017, a humanized Fab that blocks platelet's glycoprotein VI function without causing bleeding risks.

mAbs

Lebozec K, Jandrot-Perrus M, Avenard G, Favre-Bulle O, Billiald P.
PMID: 28598281
MAbs. 2017 Aug/Sep;9(6):945-958. doi: 10.1080/19420862.2017.1336592. Epub 2017 Jun 09.

Glycoprotein VI is a platelet-specific collagen receptor critical for in vivo formation of arterial thrombosis. It is also considered as an attractive target for the development of anti-thrombotic drugs because blocking glycoprotein (GP)VI inhibits platelet aggregation without inducing detrimental...

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Lebozec K, Jandrot-Perrus M, Avenard G, et al. Design, development and characterization of ACT017, a humanized Fab that blocks platelet's glycoprotein VI function without causing bleeding risks. MAbs. 2017;9(6):945-958doi: 10.1080/19420862.2017.1336592.
Lebozec, K., Jandrot-Perrus, M., Avenard, G., Favre-Bulle, O., & Billiald, P. (2017). Design, development and characterization of ACT017, a humanized Fab that blocks platelet's glycoprotein VI function without causing bleeding risks. mAbs, 9(6), 945-958. https://doi.org/10.1080/19420862.2017.1336592
Lebozec, Kristell, et al. "Design, development and characterization of ACT017, a humanized Fab that blocks platelet's glycoprotein VI function without causing bleeding risks." mAbs vol. 9,6 (2017): 945-958. doi: https://doi.org/10.1080/19420862.2017.1336592
Lebozec K, Jandrot-Perrus M, Avenard G, Favre-Bulle O, Billiald P. Design, development and characterization of ACT017, a humanized Fab that blocks platelet's glycoprotein VI function without causing bleeding risks. MAbs. 2017 Aug/Sep;9(6):945-958. doi: 10.1080/19420862.2017.1336592. Epub 2017 Jun 09. PMID: 28598281; PMCID: PMC5540112.
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Elucidation of the genetic architecture of self-incompatibility in olive: Evolutionary consequences and perspectives for orchard management.

Evolutionary applications

Saumitou-Laprade P, Vernet P, Vekemans X, Billiard S, Gallina S, Essalouh L, Mhaïs A, Moukhli A, El Bakkali A, Barcaccia G, Alagna F, Mariotti R, Cultrera NGM, Pandolfi S, Rossi M, Khadari B, Baldoni L.
PMID: 29151878
Evol Appl. 2017 May 20;10(9):867-880. doi: 10.1111/eva.12457. eCollection 2017 Oct.

The olive (

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Saumitou-Laprade P, Vernet P, Vekemans X, et al. Elucidation of the genetic architecture of self-incompatibility in olive: Evolutionary consequences and perspectives for orchard management. Evol Appl. 2017;10(9):867-880doi: 10.1111/eva.12457.
Saumitou-Laprade, P., Vernet, P., Vekemans, X., Billiard, S., Gallina, S., Essalouh, L., Mhaïs, A., Moukhli, A., El Bakkali, A., Barcaccia, G., Alagna, F., Mariotti, R., Cultrera, N. G. M., Pandolfi, S., Rossi, M., Khadari, B., & Baldoni, L. (2017). Elucidation of the genetic architecture of self-incompatibility in olive: Evolutionary consequences and perspectives for orchard management. Evolutionary applications, 10(9), 867-880. https://doi.org/10.1111/eva.12457
Saumitou-Laprade, Pierre, et al. "Elucidation of the genetic architecture of self-incompatibility in olive: Evolutionary consequences and perspectives for orchard management." Evolutionary applications vol. 10,9 (2017): 867-880. doi: https://doi.org/10.1111/eva.12457
Saumitou-Laprade P, Vernet P, Vekemans X, Billiard S, Gallina S, Essalouh L, Mhaïs A, Moukhli A, El Bakkali A, Barcaccia G, Alagna F, Mariotti R, Cultrera NGM, Pandolfi S, Rossi M, Khadari B, Baldoni L. Elucidation of the genetic architecture of self-incompatibility in olive: Evolutionary consequences and perspectives for orchard management. Evol Appl. 2017 May 20;10(9):867-880. doi: 10.1111/eva.12457. eCollection 2017 Oct. PMID: 29151878; PMCID: PMC5680433.
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Green-sensitive organic photodetectors with high sensitivity and spectral selectivity using subphthalocyanine derivatives.

ACS applied materials & interfaces

Lee KH, Leem DS, Castrucci JS, Park KB, Bulliard X, Kim KS, Jin YW, Lee S, Bender TP, Park SY.
PMID: 24274372
ACS Appl Mater Interfaces. 2013 Dec 26;5(24):13089-95. doi: 10.1021/am404122v. Epub 2013 Dec 03.

Green-sensitive organic photodetectors (OPDs) with high sensitivity and spectral selectivity using boron subphthalocyanine chloride (SubPc) derivatives are reported. The OPDs composed of SubPc and dicyanovinyl terthiophene derivative (DCV3T) demonstrated the highest green-sensitivity with maximum external quantum efficiency (EQE) of...

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Lee KH, Leem DS, Castrucci JS, et al. Green-sensitive organic photodetectors with high sensitivity and spectral selectivity using subphthalocyanine derivatives. ACS Appl Mater Interfaces. 2013;5(24):13089-95doi: 10.1021/am404122v.
Lee, K. H., Leem, D. S., Castrucci, J. S., Park, K. B., Bulliard, X., Kim, K. S., Jin, Y. W., Lee, S., Bender, T. P., & Park, S. Y. (2013). Green-sensitive organic photodetectors with high sensitivity and spectral selectivity using subphthalocyanine derivatives. ACS applied materials & interfaces, 5(24), 13089-95. https://doi.org/10.1021/am404122v
Lee, Kwang-Hee, et al. "Green-sensitive organic photodetectors with high sensitivity and spectral selectivity using subphthalocyanine derivatives." ACS applied materials & interfaces vol. 5,24 (2013): 13089-95. doi: https://doi.org/10.1021/am404122v
Lee KH, Leem DS, Castrucci JS, Park KB, Bulliard X, Kim KS, Jin YW, Lee S, Bender TP, Park SY. Green-sensitive organic photodetectors with high sensitivity and spectral selectivity using subphthalocyanine derivatives. ACS Appl Mater Interfaces. 2013 Dec 26;5(24):13089-95. doi: 10.1021/am404122v. Epub 2013 Dec 03. PMID: 24274372.
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A strategy for the stereoselective synthesis of unsymmetric atropisomeric ligands: preparation of NAPhePHOS, a new biaryl diphosphine.

Chemistry (Weinheim an der Bergstrasse, Germany)

Michaud G, Bulliard M, Ricard L, Genêt JP, Marinetti A.
PMID: 12203313
Chemistry. 2002 Aug 02;8(15):3327-30. doi: 10.1002/1521-3765(20020802)8:15<3327::AID-CHEM3327>3.0.CO;2-F.

MeO-NAPhePHOS represents the first example of a new series of atropisomeric diphosphines bearing heterotopic biaryl moieties. The key step of its synthesis is the diastereoselective, intramolecular, Cu(I)-promoted coupling of 1-iodonaphthol and 2-iodo-3-methoxyphenol connected by a chiral tether. (R,R)-2,4-Pentanediol is...

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Michaud G, Bulliard M, Ricard L, et al. A strategy for the stereoselective synthesis of unsymmetric atropisomeric ligands: preparation of NAPhePHOS, a new biaryl diphosphine. Chemistry. 2002;8(15):3327-30doi: 10.1002/1521-3765(20020802)8:15<3327::AID-CHEM3327>3.0.CO;2-F.
Michaud, G., Bulliard, M., Ricard, L., Genêt, J. P., & Marinetti, A. (2002). A strategy for the stereoselective synthesis of unsymmetric atropisomeric ligands: preparation of NAPhePHOS, a new biaryl diphosphine. Chemistry (Weinheim an der Bergstrasse, Germany), 8(15), 3327-30. https://doi.org/10.1002/1521-3765(20020802)8:15<3327::AID-CHEM3327>3.0.CO;2-F
Michaud, Guillaume, et al. "A strategy for the stereoselective synthesis of unsymmetric atropisomeric ligands: preparation of NAPhePHOS, a new biaryl diphosphine." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 8,15 (2002): 3327-30. doi: https://doi.org/10.1002/1521-3765(20020802)8:15<3327::AID-CHEM3327>3.0.CO;2-F
Michaud G, Bulliard M, Ricard L, Genêt JP, Marinetti A. A strategy for the stereoselective synthesis of unsymmetric atropisomeric ligands: preparation of NAPhePHOS, a new biaryl diphosphine. Chemistry. 2002 Aug 02;8(15):3327-30. doi: 10.1002/1521-3765(20020802)8:15<3327::AID-CHEM3327>3.0.CO;2-F. PMID: 12203313.
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[Esophageal disease: is cross sectional imaging contributive?].

Journal de radiologie

Billiard JS, Le Pennec V, Fournier L, Schmutz G.
PMID: 15184794
J Radiol. 2004 Apr;85(4):500-2. doi: 10.1016/s0221-0363(04)97621-4.

No abstract available.

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Billiard JS, Le Pennec V, Fournier L, et al. Pathologie de l'oesophage. L'imagerie en coupes a-t-elle un intérêt? [Esophageal disease: is cross sectional imaging contributive?]. J Radiol. 2004;85(4):500-2doi: 10.1016/s0221-0363(04)97621-4.
Billiard, J. S., Le Pennec, V., Fournier, L., & Schmutz, G. (2004). Pathologie de l'oesophage. L'imagerie en coupes a-t-elle un intérêt? [Esophageal disease: is cross sectional imaging contributive?]. Journal de radiologie, 85(4), 500-2. https://doi.org/10.1016/s0221-0363(04)97621-4
Billiard, J S, et al. "Pathologie de l'oesophage. L'imagerie en coupes a-t-elle un intérêt?" [Esophageal disease: is cross sectional imaging contributive?]. Journal de radiologie vol. 85,4 (2004): 500-2. doi: https://doi.org/10.1016/s0221-0363(04)97621-4
Billiard JS, Le Pennec V, Fournier L, Schmutz G. Pathologie de l'oesophage. L'imagerie en coupes a-t-elle un intérêt? [Esophageal disease: is cross sectional imaging contributive?]. J Radiol. 2004 Apr;85(4):500-2. doi: 10.1016/s0221-0363(04)97621-4. French. PMID: 15184794.
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Generation and detection of incoherent phonons in picosecond ultrasonics.

Ultrasonics

Perrin B, Péronne E, Belliard L.
PMID: 16814828
Ultrasonics. 2006 Dec 22;44:e1277-81. doi: 10.1016/j.ultras.2006.05.081. Epub 2006 Jun 05.

In picosecond ultrasonics experiments the absorption of a femtosecond laser pulse in a thin metallic transducer is used to generate very short acoustic pulses. These pulses are made of coherent longitudinal waves with a frequency spectrum that can reach...

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Perrin B, Péronne E, Belliard L. Generation and detection of incoherent phonons in picosecond ultrasonics. Ultrasonics. 2006;44:e1277-81doi: 10.1016/j.ultras.2006.05.081.
Perrin, B., Péronne, E., & Belliard, L. (2006). Generation and detection of incoherent phonons in picosecond ultrasonics. Ultrasonics, 44e1277-81. https://doi.org/10.1016/j.ultras.2006.05.081
Perrin, B, et al. "Generation and detection of incoherent phonons in picosecond ultrasonics." Ultrasonics vol. 44 (2006): e1277-81. doi: https://doi.org/10.1016/j.ultras.2006.05.081
Perrin B, Péronne E, Belliard L. Generation and detection of incoherent phonons in picosecond ultrasonics. Ultrasonics. 2006 Dec 22;44:e1277-81. doi: 10.1016/j.ultras.2006.05.081. Epub 2006 Jun 05. PMID: 16814828.
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Introduction to cardiac imaging in infants and children: techniques, potential, and role in the imaging work-up of various cardiac malformations and other pediatric heart conditions.

European journal of radiology

Bailliard F, Hughes ML, Taylor AM.
PMID: 18775615
Eur J Radiol. 2008 Nov;68(2):191-8. doi: 10.1016/j.ejrad.2008.05.016. Epub 2008 Sep 04.

The increasing prevalence of congenital heart disease (CHD) can be attributed to major improvements in diagnosis and treatment. Although echocardiography is the most commonly used imaging modality for diagnosis and follow-up of subjects with CHD, the evolution of cardiovascular...

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Bailliard F, Hughes ML, Taylor AM. Introduction to cardiac imaging in infants and children: techniques, potential, and role in the imaging work-up of various cardiac malformations and other pediatric heart conditions. Eur J Radiol. 2008;68(2):191-8doi: 10.1016/j.ejrad.2008.05.016.
Bailliard, F., Hughes, M. L., & Taylor, A. M. (2008). Introduction to cardiac imaging in infants and children: techniques, potential, and role in the imaging work-up of various cardiac malformations and other pediatric heart conditions. European journal of radiology, 68(2), 191-8. https://doi.org/10.1016/j.ejrad.2008.05.016
Bailliard, Frederique, et al. "Introduction to cardiac imaging in infants and children: techniques, potential, and role in the imaging work-up of various cardiac malformations and other pediatric heart conditions." European journal of radiology vol. 68,2 (2008): 191-8. doi: https://doi.org/10.1016/j.ejrad.2008.05.016
Bailliard F, Hughes ML, Taylor AM. Introduction to cardiac imaging in infants and children: techniques, potential, and role in the imaging work-up of various cardiac malformations and other pediatric heart conditions. Eur J Radiol. 2008 Nov;68(2):191-8. doi: 10.1016/j.ejrad.2008.05.016. Epub 2008 Sep 04. PMID: 18775615.
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Contribution of the d-Serine-Dependent Pathway to the Cellular Mechanisms Underlying Cognitive Aging.

Frontiers in aging neuroscience

Potier B, Turpin FR, Sinet PM, Rouaud E, Mothet JP, Videau C, Epelbaum J, Dutar P, Billard JM.
PMID: 20552041
Front Aging Neurosci. 2010 Feb 05;2:1. doi: 10.3389/neuro.24.001.2010. eCollection 2010.

An association between age-related memory impairments and changes in functional plasticity in the aging brain has been under intense study within the last decade. In this article, we show that an impaired activation of the strychnine-insensitive glycine site of...

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Potier B, Turpin FR, Sinet PM, et al. Contribution of the d-Serine-Dependent Pathway to the Cellular Mechanisms Underlying Cognitive Aging. Front Aging Neurosci. 2010;2:1doi: 10.3389/neuro.24.001.2010.
Potier, B., Turpin, F. R., Sinet, P. M., Rouaud, E., Mothet, J. P., Videau, C., Epelbaum, J., Dutar, P., & Billard, J. M. (2010). Contribution of the d-Serine-Dependent Pathway to the Cellular Mechanisms Underlying Cognitive Aging. Frontiers in aging neuroscience, 21. https://doi.org/10.3389/neuro.24.001.2010
Potier, B, et al. "Contribution of the d-Serine-Dependent Pathway to the Cellular Mechanisms Underlying Cognitive Aging." Frontiers in aging neuroscience vol. 2 (2010): 1. doi: https://doi.org/10.3389/neuro.24.001.2010
Potier B, Turpin FR, Sinet PM, Rouaud E, Mothet JP, Videau C, Epelbaum J, Dutar P, Billard JM. Contribution of the d-Serine-Dependent Pathway to the Cellular Mechanisms Underlying Cognitive Aging. Front Aging Neurosci. 2010 Feb 05;2:1. doi: 10.3389/neuro.24.001.2010. eCollection 2010. PMID: 20552041; PMCID: PMC2874399.
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Systemic effects of epidural methylprednisolone injection on glucose tolerance in diabetic patients.

BMC research notes

Zufferey P, Bulliard C, Gremion G, Saugy M, So A.
PMID: 22185681
BMC Res Notes. 2011 Dec 21;4:552. doi: 10.1186/1756-0500-4-552.

BACKGROUND: Several studies have shown that in diabetic patients, the glycemic profile was disturbed after intra-articular injection of corticosteroids. Little is known about the impact of epidural injection in such patients. The goal of this study was double, at...

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Zufferey P, Bulliard C, Gremion G, et al. Systemic effects of epidural methylprednisolone injection on glucose tolerance in diabetic patients. BMC Res Notes. 2011;4:552doi: 10.1186/1756-0500-4-552.
Zufferey, P., Bulliard, C., Gremion, G., Saugy, M., & So, A. (2011). Systemic effects of epidural methylprednisolone injection on glucose tolerance in diabetic patients. BMC research notes, 4552. https://doi.org/10.1186/1756-0500-4-552
Zufferey, Pascal, et al. "Systemic effects of epidural methylprednisolone injection on glucose tolerance in diabetic patients." BMC research notes vol. 4 (2011): 552. doi: https://doi.org/10.1186/1756-0500-4-552
Zufferey P, Bulliard C, Gremion G, Saugy M, So A. Systemic effects of epidural methylprednisolone injection on glucose tolerance in diabetic patients. BMC Res Notes. 2011 Dec 21;4:552. doi: 10.1186/1756-0500-4-552. PMID: 22185681; PMCID: PMC3298566.
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[How can we optimize medical orderings in intensive care unit (ICU)?].

Annales francaises d'anesthesie et de reanimation

Lehot JJ, Heuclin C, Neidecker J, Cartier R, Ffrench P, Reverdy ME, Revel D, Billard M, Lupo C, Gonnard B, Keller G, Aulagner G, Bastien O.
PMID: 20729030
Ann Fr Anesth Reanim. 2010 Oct;29(10):682-6. doi: 10.1016/j.annfar.2010.06.017. Epub 2010 Aug 21.

OBJECTIVES: To evaluate whether intensivists would accept to optimize their orderings of biological samplings, x-rays and target drugs and to assess the consequence on patient's outcome.STUDY DESIGN: Monocentric evaluation of medical economic procedure.METHODS: Meetings of consultants, registrars and residents...

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Lehot JJ, Heuclin C, Neidecker J, et al. Optimisation des prescriptions en réanimation. [How can we optimize medical orderings in intensive care unit (ICU)?]. Ann Fr Anesth Reanim. 2010;29(10):682-6doi: 10.1016/j.annfar.2010.06.017.
Lehot, J. J., Heuclin, C., Neidecker, J., Cartier, R., Ffrench, P., Reverdy, M. E., Revel, D., Billard, M., Lupo, C., Gonnard, B., Keller, G., Aulagner, G., & Bastien, O. (2010). Optimisation des prescriptions en réanimation. [How can we optimize medical orderings in intensive care unit (ICU)?]. Annales francaises d'anesthesie et de reanimation, 29(10), 682-6. https://doi.org/10.1016/j.annfar.2010.06.017
Lehot, J-J, et al. "Optimisation des prescriptions en réanimation." [How can we optimize medical orderings in intensive care unit (ICU)?]. Annales francaises d'anesthesie et de reanimation vol. 29,10 (2010): 682-6. doi: https://doi.org/10.1016/j.annfar.2010.06.017
Lehot JJ, Heuclin C, Neidecker J, Cartier R, Ffrench P, Reverdy ME, Revel D, Billard M, Lupo C, Gonnard B, Keller G, Aulagner G, Bastien O. Optimisation des prescriptions en réanimation. [How can we optimize medical orderings in intensive care unit (ICU)?]. Ann Fr Anesth Reanim. 2010 Oct;29(10):682-6. doi: 10.1016/j.annfar.2010.06.017. Epub 2010 Aug 21. French. PMID: 20729030.
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Ab initio molecular crystal structures, spectra, and phase diagrams.

Accounts of chemical research

Hirata S, Gilliard K, He X, Li J, Sode O.
PMID: 24754304
Acc Chem Res. 2014 Sep 16;47(9):2721-30. doi: 10.1021/ar500041m. Epub 2014 Apr 22.

Conspectus Molecular crystals are chemists' solids in the sense that their structures and properties can be understood in terms of those of the constituent molecules merely perturbed by a crystalline environment. They form a large and important class of...

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Hirata S, Gilliard K, He X, et al. Ab initio molecular crystal structures, spectra, and phase diagrams. Acc Chem Res. 2014;47(9):2721-30doi: 10.1021/ar500041m.
Hirata, S., Gilliard, K., He, X., Li, J., & Sode, O. (2014). Ab initio molecular crystal structures, spectra, and phase diagrams. Accounts of chemical research, 47(9), 2721-30. https://doi.org/10.1021/ar500041m
Hirata, So, et al. "Ab initio molecular crystal structures, spectra, and phase diagrams." Accounts of chemical research vol. 47,9 (2014): 2721-30. doi: https://doi.org/10.1021/ar500041m
Hirata S, Gilliard K, He X, Li J, Sode O. Ab initio molecular crystal structures, spectra, and phase diagrams. Acc Chem Res. 2014 Sep 16;47(9):2721-30. doi: 10.1021/ar500041m. Epub 2014 Apr 22. PMID: 24754304.
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Hippocampal subfield volumetry in mild cognitive impairment, Alzheimer's disease and semantic dementia.

NeuroImage. Clinical

La Joie R, Perrotin A, de La Sayette V, Egret S, Doeuvre L, Belliard S, Eustache F, Desgranges B, Chételat G.
PMID: 24179859
Neuroimage Clin. 2013 Aug 14;3:155-62. doi: 10.1016/j.nicl.2013.08.007. eCollection 2013.

BACKGROUND: Hippocampal atrophy is a well-known feature of Alzheimer's disease (AD), but sensitivity and specificity of hippocampal volumetry are limited. Neuropathological studies have shown that hippocampal subfields are differentially vulnerable to AD; hippocampal subfield volumetry may thus prove to...

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La Joie R, Perrotin A, de La Sayette V, et al. Hippocampal subfield volumetry in mild cognitive impairment, Alzheimer's disease and semantic dementia. Neuroimage Clin. 2013;3:155-62doi: 10.1016/j.nicl.2013.08.007.
La Joie, R., Perrotin, A., de La Sayette, V., Egret, S., Doeuvre, L., Belliard, S., Eustache, F., Desgranges, B., & Chételat, G. (2013). Hippocampal subfield volumetry in mild cognitive impairment, Alzheimer's disease and semantic dementia. NeuroImage. Clinical, 3155-62. https://doi.org/10.1016/j.nicl.2013.08.007
La Joie, Renaud, et al. "Hippocampal subfield volumetry in mild cognitive impairment, Alzheimer's disease and semantic dementia." NeuroImage. Clinical vol. 3 (2013): 155-62. doi: https://doi.org/10.1016/j.nicl.2013.08.007
La Joie R, Perrotin A, de La Sayette V, Egret S, Doeuvre L, Belliard S, Eustache F, Desgranges B, Chételat G. Hippocampal subfield volumetry in mild cognitive impairment, Alzheimer's disease and semantic dementia. Neuroimage Clin. 2013 Aug 14;3:155-62. doi: 10.1016/j.nicl.2013.08.007. eCollection 2013. PMID: 24179859; PMCID: PMC3791274.
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