Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 22 entries
Sorted by: Best Match Show Resources per page
The invasive proteome of glioblastoma revealed by laser-capture microdissection.

Neuro-oncology advances

Daubon T, Guyon J, Raymond AA, Dartigues B, Rudewicz J, Ezzoukhry Z, Dupuy JW, Herbert JMJ, Saltel F, Bjerkvig R, Nikolski M, Bikfalvi A.
PMID: 32642662
Neurooncol Adv. 2019 Sep 28;1(1):vdz029. doi: 10.1093/noajnl/vdz029. eCollection 2019.

BACKGROUND: Glioblastomas are heterogeneous tumors composed of a necrotic and tumor core and an invasive periphery.METHODS: Here, we performed a proteomics analysis of laser-capture micro-dissected glioblastoma core and invasive areas of patient-derived xenografts.RESULTS: Bioinformatics analysis identified enriched proteins in...

TGF-β promotes microtube formation in glioblastoma through thrombospondin 1.

Neuro-oncology

Joseph JV, Magaut CR, Storevik S, Geraldo LH, Mathivet T, Latif MA, Rudewicz J, Guyon J, Gambaretti M, Haukas F, Trones A, Rømo Ystaas LA, Hossain JA, Ninzima S, Cuvellier S, Zhou W, Tomar T, Klink B, Rane L, Irving BK, Marrison J, O'Toole P, Wurdak H, Wang J, Di Z, Birkeland E, Berven FS, Winkler F, Kruyt FAE, Bikfalvi A, Bjerkvig R, Daubon T, Miletic H.
PMID: 34543427
Neuro Oncol. 2021 Sep 20; doi: 10.1093/neuonc/noab212. Epub 2021 Sep 20.

BACKGROUND: Microtubes (MTs), cytoplasmic extensions of glioma cells, are important cell communication structures promoting invasion and treatment resistance through network formation. MTs are abundant in chemoresistant gliomas, in particular glioblastomas (GBMs), while they are uncommon in chemosensitive IDH-mutant and...

[Education--expectations and reality].

Tidsskriftet sykepleien

Bjerkvik L.
PMID: 9512641
Tidsskr Sykepl. 1998 Feb 10;86(3):52-5.

No abstract available.

Mutant IDH1 Differently Affects Redox State and Metabolism in Glial Cells of Normal and Tumor Origin.

Cancers

Biedermann J, Preussler M, Conde M, Peitzsch M, Richter S, Wiedemuth R, Abou-El-Ardat K, Krüger A, Meinhardt M, Schackert G, Leenders WP, Herold-Mende C, Niclou SP, Bjerkvig R, Eisenhofer G, Temme A, Seifert M, Kunz-Schughart LA, Schröck E, Klink B.
PMID: 31888244
Cancers (Basel). 2019 Dec 16;11(12). doi: 10.3390/cancers11122028.

IDH1

Primary organ-culture of nonneoplastic and neoplastic thyroid-tissue as multicellular spheroids.

International journal of oncology

Ness G, Bjerkvig R, Akslen L, Lillehaug J, Varhaug J.
PMID: 21556642
Int J Oncol. 1995 May;6(5):1071-8. doi: 10.3892/ijo.6.5.1071.

Biopsy specimens from 5 papillary thyroid carcinomas (PC), 2 lymph node metastases (LM) from PC, 3 colloid goitres (CG) and 7 normal (N) thyroid tissue were maintained as three-dimensional structures in agar overlay culture for up to 6 weeks....

Identification of a novel lytic peptide for the treatment of solid tumours.

Genes & cancer

Szczepanski C, Tenstad O, Baumann A, Martinez A, Myklebust R, Bjerkvig R, Prestegarden L.
PMID: 25061502
Genes Cancer. 2014 May;5(5):186-200. doi: 10.18632/genesandcancer.18.

Originally known as host defence peptides for their substantial bacteriotoxic effects, many cationic antimicrobial peptides also exhibit a potent cytotoxic activity against cancer cells. Their mode of action is characterized mostly by electrostatic interactions with the plasma membrane, leading...

Identification of a Blood-Based Protein Biomarker Panel for Lung Cancer Detection.

Cancers

El-Khoury V, Schritz A, Kim SY, Lesur A, Sertamo K, Bernardin F, Petritis K, Pirrotte P, Selinsky C, Whiteaker JR, Zhang H, Kennedy JJ, Lin C, Lee LW, Yan P, Tran NL, Inge LJ, Chalabi K, Decker G, Bjerkvig R, Paulovich AG, Berchem G, Kim YJ.
PMID: 32575471
Cancers (Basel). 2020 Jun 19;12(6). doi: 10.3390/cancers12061629.

Lung cancer is the deadliest cancer worldwide, mainly due to its advanced stage at the time of diagnosis. A non-invasive method for its early detection remains mandatory to improve patients' survival. Plasma levels of 351 proteins were quantified by...

Novel facets of glioma invasion.

International review of cell and molecular biology

Fabian C, Han M, Bjerkvig R, Niclou SP.
PMID: 33962750
Int Rev Cell Mol Biol. 2021;360:33-64. doi: 10.1016/bs.ircmb.2020.08.001. Epub 2020 Oct 17.

Malignant gliomas including Glioblastoma (GBM) are characterized by extensive diffuse tumor cell infiltration throughout the brain, which represents a major challenge in clinical disease management. While surgical resection is beneficial for patient outcome, it is well recognized that tumor...

TGF-β promotes microtube formation in glioblastoma through thrombospondin 1.

Neuro-oncology

Joseph JV, Magaut CR, Storevik S, Geraldo LH, Mathivet T, Latif MA, Rudewicz J, Guyon J, Gambaretti M, Haukas F, Trones A, Rømo Ystaas LA, Hossain JA, Ninzima S, Cuvellier S, Zhou W, Tomar T, Klink B, Rane L, Irving BK, Marrison J, O'Toole P, Wurdak H, Wang J, Di Z, Birkeland E, Berven FS, Winkler F, Kruyt FAE, Bikfalvi A, Bjerkvig R, Daubon T, Miletic H.
PMID: 34543427
Neuro Oncol. 2021 Sep 20; doi: 10.1093/neuonc/noab212. Epub 2021 Sep 20.

BACKGROUND: Microtubes (MTs), cytoplasmic extensions of glioma cells, are important cell communication structures promoting invasion and treatment resistance through network formation. MTs are abundant in chemoresistant gliomas, in particular glioblastomas (GBMs), while they are uncommon in chemosensitive IDH-mutant and...

Current landscape and future perspectives in preclinical MR and PET imaging of brain metastasis.

Neuro-oncology advances

Aasen SN, Espedal H, Keunen O, Adamsen TCH, Bjerkvig R, Thorsen F.
PMID: 34988446
Neurooncol Adv. 2021 Oct 14;3(1):vdab151. doi: 10.1093/noajnl/vdab151. eCollection 2021.

Brain metastasis (BM) is a major cause of cancer patient morbidity. Clinical magnetic resonance imaging (MRI) and positron emission tomography (PET) represent important resources to assess tumor progression and treatment responses. In preclinical research, anatomical MRI and to some...

Protocol for derivation of organoids and patient-derived orthotopic xenografts from glioma patient tumors.

STAR protocols

Oudin A, Baus V, Barthelemy V, Fabian C, Klein E, Dieterle M, Wantz M, Hau AC, Dording C, Bernard A, Michelucci A, Yabo YA, Kanli G, Keunen O, Bjerkvig R, Niclou SP, Golebiewska A.
PMID: 34027491
STAR Protoc. 2021 May 12;2(2):100534. doi: 10.1016/j.xpro.2021.100534. eCollection 2021 Jun 18.

Tumor organoids and patient-derived orthotopic xenografts (PDOXs) are some of the most valuable pre-clinical tools in cancer research. In this protocol, we describe efficient derivation of organoids and PDOX models from glioma patient tumors. We provide detailed steps for...

Surgical resection of glioblastomas induces pleiotrophin-mediated self-renewal of glioblastoma stem cells in recurrent tumors.

Neuro-oncology

Knudsen AM, Halle B, Cédile O, Burton M, Baun C, Thisgaard H, Anand A, Hubert C, Thomassen M, Michaelsen SR, Olsen BB, Dahlrot RH, Bjerkvig R, Lathia JD, Kristensen BW.
PMID: 34964899
Neuro Oncol. 2021 Dec 29; doi: 10.1093/neuonc/noab302. Epub 2021 Dec 29.

BACKGROUND: Glioblastomas are highly resistant to therapy, and virtually all patients experience tumor recurrence after standard-of-care treatment. Surgical tumor resection is a cornerstone in glioblastoma therapy, but its impact on cellular phenotypes in the local post-surgical microenvironment has yet...

Showing 1 to 12 of 22 entries