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The nature of polymorphism of the HLA class I non‐coding regions and their contribution to the diversification of HLA

STEM and diversification

Blasczyk R.
GSID: mnqUJKIRxhoJ
R Blasczyk, K Kotsch, J Wehling - Hereditas, 1997 - Wiley Online Library

… , promoting the potential to extrude single‐strand stem‐loops from supercoiled duplex DNA, … Since there are less diversification forces acting on introns they may be more conserved in …

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Blasczyk, R., Kotsch, K., & Wehling, J. (1997). The nature of polymorphism of the HLA class I non‐coding regions and their contribution to the diversification of HLA. Hereditas, 127(1‐2), 7-9.
Blasczyk, Rainer, Katja Kotsch, and Jenny Wehling. "The nature of polymorphism of the HLA class I non‐coding regions and their contribution to the diversification of HLA." Hereditas 127.1‐2 (1997): 7-9.
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Target Identification of .

Frontiers in pharmacology

Mugumbate G, Mendes V, Blaszczyk M, Sabbah M, Papadatos G, Lelievre J, Ballell L, Barros D, Abell C, Blundell TL, Overington JP.
PMID: 29018348
Front Pharmacol. 2017 Sep 26;8:681. doi: 10.3389/fphar.2017.00681. eCollection 2017.

Mycobacterium phenotypic hits are a good reservoir for new chemotypes for the treatment of tuberculosis. However, the absence of defined molecular targets and modes of action could lead to failure in drug development. Therefore, a combination of ligand-based and...

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Mugumbate G, Mendes V, Blaszczyk M, et al. Target Identification of . Front Pharmacol. 2017;8:681doi: 10.3389/fphar.2017.00681.
Mugumbate, G., Mendes, V., Blaszczyk, M., Sabbah, M., Papadatos, G., Lelievre, J., Ballell, L., Barros, D., Abell, C., Blundell, T. L., & Overington, J. P. (2017). Target Identification of . Frontiers in pharmacology, 8681. https://doi.org/10.3389/fphar.2017.00681
Mugumbate, Grace, et al. "Target Identification of ." Frontiers in pharmacology vol. 8 (2017): 681. doi: https://doi.org/10.3389/fphar.2017.00681
Mugumbate G, Mendes V, Blaszczyk M, Sabbah M, Papadatos G, Lelievre J, Ballell L, Barros D, Abell C, Blundell TL, Overington JP. Target Identification of . Front Pharmacol. 2017 Sep 26;8:681. doi: 10.3389/fphar.2017.00681. eCollection 2017. PMID: 29018348; PMCID: PMC5623190.
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Generation of HLA-Universal iPSC-Derived Megakaryocytes and Platelets for Survival Under Refractoriness Conditions.

Molecular medicine (Cambridge, Mass.)

Börger AK, Eicke D, Wolf C, Gras C, Aufderbeck S, Schulze K, Engels L, Eiz-Vesper B, Schambach A, Guzman CA, Lachmann N, Moritz T, Martin U, Blasczyk R, Figueiredo C.
PMID: 27262025
Mol Med. 2016 Sep;22:274-285. doi: 10.2119/molmed.2015.00235. Epub 2016 May 16.

Platelet (PLT) transfusion is indispensable to maintain homeostasis in thrombocytopenic patients. However, PLT transfusion refractoriness is a common life-threatening condition observed in multitransfused patients. The most frequent immune cause for PLT transfusion refractoriness is the presence of alloantibodies specific...

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Börger AK, Eicke D, Wolf C, et al. Generation of HLA-Universal iPSC-Derived Megakaryocytes and Platelets for Survival Under Refractoriness Conditions. Mol Med. 2016;22:274-285doi: 10.2119/molmed.2015.00235.
Börger, A. K., Eicke, D., Wolf, C., Gras, C., Aufderbeck, S., Schulze, K., Engels, L., Eiz-Vesper, B., Schambach, A., Guzman, C. A., Lachmann, N., Moritz, T., Martin, U., Blasczyk, R., & Figueiredo, C. (2016). Generation of HLA-Universal iPSC-Derived Megakaryocytes and Platelets for Survival Under Refractoriness Conditions. Molecular medicine (Cambridge, Mass.), 22274-285. https://doi.org/10.2119/molmed.2015.00235
Börger, Ann-Kathrin, et al. "Generation of HLA-Universal iPSC-Derived Megakaryocytes and Platelets for Survival Under Refractoriness Conditions." Molecular medicine (Cambridge, Mass.) vol. 22 (2016): 274-285. doi: https://doi.org/10.2119/molmed.2015.00235
Börger AK, Eicke D, Wolf C, Gras C, Aufderbeck S, Schulze K, Engels L, Eiz-Vesper B, Schambach A, Guzman CA, Lachmann N, Moritz T, Martin U, Blasczyk R, Figueiredo C. Generation of HLA-Universal iPSC-Derived Megakaryocytes and Platelets for Survival Under Refractoriness Conditions. Mol Med. 2016 Sep;22:274-285. doi: 10.2119/molmed.2015.00235. Epub 2016 May 16. PMID: 27262025; PMCID: PMC5023513.
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Bromine catalyzed conversion of S-tert-butyl groups into versatile and, for self-assembly processes accessible, acetyl-protected thiols.

Organic & biomolecular chemistry

Blaszczyk A, Elbing M, Mayor M.
PMID: 15455141
Org Biomol Chem. 2004 Oct 07;2(19):2722-4. doi: 10.1039/B408677E. Epub 2004 Sep 13.

The facile and efficient conversion of a tert-butyl protecting group to an acetyl protecting group for thiols by catalytic amounts of bromine in acetyl chloride and the presence of acetic acid has been developed. The fairly mild reaction conditions...

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Blaszczyk A, Elbing M, Mayor M. Bromine catalyzed conversion of S-tert-butyl groups into versatile and, for self-assembly processes accessible, acetyl-protected thiols. Org Biomol Chem. 2004;2(19):2722-4doi: 10.1039/B408677E.
Blaszczyk, A., Elbing, M., & Mayor, M. (2004). Bromine catalyzed conversion of S-tert-butyl groups into versatile and, for self-assembly processes accessible, acetyl-protected thiols. Organic & biomolecular chemistry, 2(19), 2722-4. https://doi.org/10.1039/B408677E
Blaszczyk, Alfred, et al. "Bromine catalyzed conversion of S-tert-butyl groups into versatile and, for self-assembly processes accessible, acetyl-protected thiols." Organic & biomolecular chemistry vol. 2,19 (2004): 2722-4. doi: https://doi.org/10.1039/B408677E
Blaszczyk A, Elbing M, Mayor M. Bromine catalyzed conversion of S-tert-butyl groups into versatile and, for self-assembly processes accessible, acetyl-protected thiols. Org Biomol Chem. 2004 Oct 07;2(19):2722-4. doi: 10.1039/B408677E. Epub 2004 Sep 13. PMID: 15455141.
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Search for the photoexcitation of exotic mesons in the pi+pi+pi- system.

Physical review letters

Nozar M, Salgado C, Weygand DP, Guo L, Adams G, Li J, Eugenio P, Amaryan MJ, Anghinolfi M, Asryan G, Avakian H, Bagdasaryan H, Baillie N, Ball JP, Baltzell NA, Barrow S, Battaglieri M, Bedlinskiy I, Bektasoglu M, Bellis M, Benmouna N, Berman BL, Biselli AS, Blaszczyk L, Bonner BE, Bouchigny S, Boiarinov S, Bradford R, Branford D, Briscoe WJ, Brooks WK, Bültmann S, Burkert VD, Butuceanu C, Calarco JR, Careccia SL, Carman DS, Carnahan B, Casey L, Cazes A, Chen S, Cheng L, Cole PL, Collins P, Coltharp P, Cords D, Corvisiero P, Crabb D, Crannell H, Crede V, Cummings JP, Dale D, Dashyan N, De Masi R, De Vita R, De Sanctis E, Degtyarenko PV, Denizli H, Dennis L, Deur A, Dharmawardane KV, Dhuga KS, Dickson R, Djalali C, Dodge GE, Doughty D, Dugger M, Dytman S, Dzyubak OP, Egiyan H, Egiyan KS, El Fassi L, Elouadrhiri L, Fatemi R, Fedotov G, Feuerbach RJ, Forest TA, Fradi A, Funsten H, Garçon M, Gavalian G, Gevorgyan N, Gilfoyle GP, Giovanetti KL, Girod FX, Goetz JT, Gothe RW, Griffioen KA, Guidal M, Guillo M, Guler N, Gyurjyan V, Hadjidakis C, Hafidi K, Hakobyan H, Hanretty C, Hardie J, Hassall N, Heddle D, Hersman FW, Hicks K, Hleiqawi I, Holtrop M, Hyde-Wright CE, Ilieva Y, Ireland DG, Ishkhanov BS, Isupov EL, Ito MM, Jenkins D, Jo HS, Johnstone JR, Joo K, Juengst HG, Kalantarians N, Kellie JD, Khandaker M, Kim W, Klein A, Klein FJ, Kossov M, Krahn Z, Kramer LH, Kubarovsky V, Kuhn J, Kuhn SE, Kuleshov SV, Kuznetsov V, Lachniet J, Laget JM, Langheinrich J, Lawrence D, Livingston K, Lu HY, Maccormick M, Markov N, Mattione P, McAleer S, McKinnon B, McNabb JW, Mecking BA, Mehrabyan S, Mestayer MD, Meyer CA, Mibe T, Mikhailov K, Mirazita M, Miskimen R, Mokeev V, Moreno B, Moriya K, Morrow SA, Moteabbed M, Mueller J, Munevar E, Mutchler GS, Nadel-Turonski P, Nasseripour R, Niccolai S, Niculescu G, Niculescu I, Niczyporuk BB, Niroula MR, Niyazov RA, O'Rielly GV, Osipenko M, Ostrovidov AI, Park K, Pasyuk E, Paterson C, Anefalos Pereira S, Philips SA, Pierce J, Pivnyuk N, Pocanic D, Pogorelko O, Polli E, Popa I, Pozdniakov S, Preedom BM, Price JW, Prok Y, Protopopescu D, Qin LM, Raue BA, Riccardi G, Ricco G, Ripani M, Ritchie BG, Ronchetti F, Rosner G, Rossi P, Rubin PD, Sabatié F, Salamanca J, Santoro JP, Sapunenko V, Schumacher RA, Serov VS, Sharabian YG, Sharov D, Shvedunov NV, Skabelin AV, Smith ES, Smith LC, Sober DI, Sokhan D, Stavinsky A, Stepanyan SS, Stepanyan S, Stokes BE, Stoler P, Strakovsky II, Strauch S, Taiuti M, Tedeschi DJ, Thoma U, Tkabladze A, Tkachenko S, Todor L, Ungaro M, Vineyard MF, Vlassov AV, Watts DP, Weinstein LB, Williams M, Wolin E, Wood MH, Yegneswaran A, Zana L, Zhang J, Zhao B, Zhao ZW.
PMID: 19392105
Phys Rev Lett. 2009 Mar 13;102(10):102002. doi: 10.1103/PhysRevLett.102.102002. Epub 2009 Mar 12.

A search for exotic mesons in the pi;{+}pi;{+}pi;{-} system photoproduced by the charge exchange reaction gammap-->pi;{+}pi;{+}pi;{-}(n) was carried out by the CLAS Collaboration at Jefferson Lab. A tagged-photon beam with energies in the 4.8 to 5.4 GeV range, produced...

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Nozar M, Salgado C, Weygand DP, et al. Search for the photoexcitation of exotic mesons in the pi+pi+pi- system. Phys Rev Lett. 2009;102(10):102002doi: 10.1103/PhysRevLett.102.102002.
Nozar, M., Salgado, C., Weygand, D. P., Guo, L., Adams, G., Li, J., Eugenio, P., Amaryan, M. J., Anghinolfi, M., Asryan, G., Avakian, H., Bagdasaryan, H., Baillie, N., Ball, J. P., Baltzell, N. A., Barrow, S., Battaglieri, M., Bedlinskiy, I., Bektasoglu, M., Bellis, M., Benmouna, N., Berman, B. L., Biselli, A. S., Blaszczyk, L., Bonner, B. E., Bouchigny, S., Boiarinov, S., Bradford, R., Branford, D., Briscoe, W. J., Brooks, W. K., Bültmann, S., Burkert, V. D., Butuceanu, C., Calarco, J. R., Careccia, S. L., Carman, D. S., Carnahan, B., Casey, L., Cazes, A., Chen, S., Cheng, L., Cole, P. L., Collins, P., Coltharp, P., Cords, D., Corvisiero, P., Crabb, D., Crannell, H., Crede, V., Cummings, J. P., Dale, D., Dashyan, N., De Masi, R., De Vita, R., De Sanctis, E., Degtyarenko, P. V., Denizli, H., Dennis, L., Deur, A., Dharmawardane, K. V., Dhuga, K. S., Dickson, R., Djalali, C., Dodge, G. E., Doughty, D., Dugger, M., Dytman, S., Dzyubak, O. P., Egiyan, H., Egiyan, K. S., El Fassi, L., Elouadrhiri, L., Fatemi, R., Fedotov, G., Feuerbach, R. J., Forest, T. A., Fradi, A., Funsten, H., Garçon, M., Gavalian, G., Gevorgyan, N., Gilfoyle, G. P., Giovanetti, K. L., Girod, F. X., Goetz, J. T., Gothe, R. W., Griffioen, K. A., Guidal, M., Guillo, M., Guler, N., Gyurjyan, V., Hadjidakis, C., Hafidi, K., Hakobyan, H., Hanretty, C., Hardie, J., Hassall, N., Heddle, D., Hersman, F. W., Hicks, K., Hleiqawi, I., Holtrop, M., Hyde-Wright, C. E., Ilieva, Y., Ireland, D. G., Ishkhanov, B. S., Isupov, E. L., Ito, M. M., Jenkins, D., Jo, H. S., Johnstone, J. R., Joo, K., Juengst, H. G., Kalantarians, N., Kellie, J. D., Khandaker, M., Kim, W., Klein, A., Klein, F. J., Kossov, M., Krahn, Z., Kramer, L. H., Kubarovsky, V., Kuhn, J., Kuhn, S. E., Kuleshov, S. V., Kuznetsov, V., Lachniet, J., Laget, J. M., Langheinrich, J., Lawrence, D., Livingston, K., Lu, H. Y., Maccormick, M., Markov, N., Mattione, P., McAleer, S., McKinnon, B., McNabb, J. W., Mecking, B. A., Mehrabyan, S., Mestayer, M. D., Meyer, C. A., Mibe, T., Mikhailov, K., Mirazita, M., Miskimen, R., Mokeev, V., Moreno, B., Moriya, K., Morrow, S. A., Moteabbed, M., Mueller, J., Munevar, E., Mutchler, G. S., Nadel-Turonski, P., Nasseripour, R., Niccolai, S., Niculescu, G., Niculescu, I., Niczyporuk, B. B., Niroula, M. R., Niyazov, R. A., O'Rielly, G. V., Osipenko, M., Ostrovidov, A. I., Park, K., Pasyuk, E., Paterson, C., Anefalos Pereira, S., Philips, S. A., Pierce, J., Pivnyuk, N., Pocanic, D., Pogorelko, O., Polli, E., Popa, I., Pozdniakov, S., Preedom, B. M., Price, J. W., Prok, Y., Protopopescu, D., Qin, L. M., Raue, B. A., Riccardi, G., Ricco, G., Ripani, M., Ritchie, B. G., Ronchetti, F., Rosner, G., Rossi, P., Rubin, P. D., Sabatié, F., Salamanca, J., Santoro, J. P., Sapunenko, V., Schumacher, R. A., Serov, V. S., Sharabian, Y. G., Sharov, D., Shvedunov, N. V., Skabelin, A. V., Smith, E. S., Smith, L. C., Sober, D. I., Sokhan, D., Stavinsky, A., Stepanyan, S. S., Stepanyan, S., Stokes, B. E., Stoler, P., Strakovsky, I. I., Strauch, S., Taiuti, M., Tedeschi, D. J., Thoma, U., Tkabladze, A., Tkachenko, S., Todor, L., Ungaro, M., Vineyard, M. F., Vlassov, A. V., Watts, D. P., Weinstein, L. B., Williams, M., Wolin, E., Wood, M. H., Yegneswaran, A., Zana, L., Zhang, J., Zhao, B., Zhao, Z. W. (2009). Search for the photoexcitation of exotic mesons in the pi+pi+pi- system. Physical review letters, 102(10), 102002. https://doi.org/10.1103/PhysRevLett.102.102002
Nozar, M, et al. "Search for the photoexcitation of exotic mesons in the pi+pi+pi- system." Physical review letters vol. 102,10 (2009): 102002. doi: https://doi.org/10.1103/PhysRevLett.102.102002
Nozar M, Salgado C, Weygand DP, Guo L, Adams G, Li J, Eugenio P, Amaryan MJ, Anghinolfi M, Asryan G, Avakian H, Bagdasaryan H, Baillie N, Ball JP, Baltzell NA, Barrow S, Battaglieri M, Bedlinskiy I, Bektasoglu M, Bellis M, Benmouna N, Berman BL, Biselli AS, Blaszczyk L, Bonner BE, Bouchigny S, Boiarinov S, Bradford R, Branford D, Briscoe WJ, Brooks WK, Bültmann S, Burkert VD, Butuceanu C, Calarco JR, Careccia SL, Carman DS, Carnahan B, Casey L, Cazes A, Chen S, Cheng L, Cole PL, Collins P, Coltharp P, Cords D, Corvisiero P, Crabb D, Crannell H, Crede V, Cummings JP, Dale D, Dashyan N, De Masi R, De Vita R, De Sanctis E, Degtyarenko PV, Denizli H, Dennis L, Deur A, Dharmawardane KV, Dhuga KS, Dickson R, Djalali C, Dodge GE, Doughty D, Dugger M, Dytman S, Dzyubak OP, Egiyan H, Egiyan KS, El Fassi L, Elouadrhiri L, Fatemi R, Fedotov G, Feuerbach RJ, Forest TA, Fradi A, Funsten H, Garçon M, Gavalian G, Gevorgyan N, Gilfoyle GP, Giovanetti KL, Girod FX, Goetz JT, Gothe RW, Griffioen KA, Guidal M, Guillo M, Guler N, Gyurjyan V, Hadjidakis C, Hafidi K, Hakobyan H, Hanretty C, Hardie J, Hassall N, Heddle D, Hersman FW, Hicks K, Hleiqawi I, Holtrop M, Hyde-Wright CE, Ilieva Y, Ireland DG, Ishkhanov BS, Isupov EL, Ito MM, Jenkins D, Jo HS, Johnstone JR, Joo K, Juengst HG, Kalantarians N, Kellie JD, Khandaker M, Kim W, Klein A, Klein FJ, Kossov M, Krahn Z, Kramer LH, Kubarovsky V, Kuhn J, Kuhn SE, Kuleshov SV, Kuznetsov V, Lachniet J, Laget JM, Langheinrich J, Lawrence D, Livingston K, Lu HY, Maccormick M, Markov N, Mattione P, McAleer S, McKinnon B, McNabb JW, Mecking BA, Mehrabyan S, Mestayer MD, Meyer CA, Mibe T, Mikhailov K, Mirazita M, Miskimen R, Mokeev V, Moreno B, Moriya K, Morrow SA, Moteabbed M, Mueller J, Munevar E, Mutchler GS, Nadel-Turonski P, Nasseripour R, Niccolai S, Niculescu G, Niculescu I, Niczyporuk BB, Niroula MR, Niyazov RA, O'Rielly GV, Osipenko M, Ostrovidov AI, Park K, Pasyuk E, Paterson C, Anefalos Pereira S, Philips SA, Pierce J, Pivnyuk N, Pocanic D, Pogorelko O, Polli E, Popa I, Pozdniakov S, Preedom BM, Price JW, Prok Y, Protopopescu D, Qin LM, Raue BA, Riccardi G, Ricco G, Ripani M, Ritchie BG, Ronchetti F, Rosner G, Rossi P, Rubin PD, Sabatié F, Salamanca J, Santoro JP, Sapunenko V, Schumacher RA, Serov VS, Sharabian YG, Sharov D, Shvedunov NV, Skabelin AV, Smith ES, Smith LC, Sober DI, Sokhan D, Stavinsky A, Stepanyan SS, Stepanyan S, Stokes BE, Stoler P, Strakovsky II, Strauch S, Taiuti M, Tedeschi DJ, Thoma U, Tkabladze A, Tkachenko S, Todor L, Ungaro M, Vineyard MF, Vlassov AV, Watts DP, Weinstein LB, Williams M, Wolin E, Wood MH, Yegneswaran A, Zana L, Zhang J, Zhao B, Zhao ZW. Search for the photoexcitation of exotic mesons in the pi+pi+pi- system. Phys Rev Lett. 2009 Mar 13;102(10):102002. doi: 10.1103/PhysRevLett.102.102002. Epub 2009 Mar 12. PMID: 19392105.
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Stereochemical effects in fragmentation of diastereoisomers of protected diethyl 1,2-diamino-alkylphosphonates.

Rapid communications in mass spectrometry : RCM

Drabik E, Błaszczyk R, Gajda T, Sochacki M.
PMID: 20658678
Rapid Commun Mass Spectrom. 2010 Aug 30;24(16):2324-8. doi: 10.1002/rcm.4644.

Diastereoisomers of diethyl 5-substituted (2-thioxo-imidazolidin-4-yl)phosphonates, which can be regarded as protected diethyl 1,2-diaminoalkylphosphonates, have been analyzed by electron ionization mass spectrometry. Significant differences in the fragmentation of cis- and trans-diastereoisomers were found. The stereospecificity of the elimination of diethyl...

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Drabik E, Błaszczyk R, Gajda T, et al. Stereochemical effects in fragmentation of diastereoisomers of protected diethyl 1,2-diamino-alkylphosphonates. Rapid Commun Mass Spectrom. 2010;24(16):2324-8doi: 10.1002/rcm.4644.
Drabik, E., Błaszczyk, R., Gajda, T., & Sochacki, M. (2010). Stereochemical effects in fragmentation of diastereoisomers of protected diethyl 1,2-diamino-alkylphosphonates. Rapid communications in mass spectrometry : RCM, 24(16), 2324-8. https://doi.org/10.1002/rcm.4644
Drabik, Ewelina, et al. "Stereochemical effects in fragmentation of diastereoisomers of protected diethyl 1,2-diamino-alkylphosphonates." Rapid communications in mass spectrometry : RCM vol. 24,16 (2010): 2324-8. doi: https://doi.org/10.1002/rcm.4644
Drabik E, Błaszczyk R, Gajda T, Sochacki M. Stereochemical effects in fragmentation of diastereoisomers of protected diethyl 1,2-diamino-alkylphosphonates. Rapid Commun Mass Spectrom. 2010 Aug 30;24(16):2324-8. doi: 10.1002/rcm.4644. PMID: 20658678.
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Crystallographic and molecular dynamics simulation analysis of Escherichia coli dihydroneopterin aldolase.

Cell & bioscience

Blaszczyk J, Lu Z, Li Y, Yan H, Ji X.
PMID: 25264482
Cell Biosci. 2014 Sep 02;4(1):52. doi: 10.1186/2045-3701-4-52. eCollection 2014.

BACKGROUND: Dihydroneopterin aldolase (DHNA) catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and also the epimerization of DHNP to 7,8-dihydromonapterin. Previously, we determined the crystal structure of Staphylococcus aureus DHNA (SaDHNA) in complex with the substrate analogue neopterin (NP). We...

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Blaszczyk J, Lu Z, Li Y, et al. Crystallographic and molecular dynamics simulation analysis of Escherichia coli dihydroneopterin aldolase. Cell Biosci. 2014;4(1):52doi: 10.1186/2045-3701-4-52.
Blaszczyk, J., Lu, Z., Li, Y., Yan, H., & Ji, X. (2014). Crystallographic and molecular dynamics simulation analysis of Escherichia coli dihydroneopterin aldolase. Cell & bioscience, 4(1), 52. https://doi.org/10.1186/2045-3701-4-52
Blaszczyk, Jaroslaw, et al. "Crystallographic and molecular dynamics simulation analysis of Escherichia coli dihydroneopterin aldolase." Cell & bioscience vol. 4,1 (2014): 52. doi: https://doi.org/10.1186/2045-3701-4-52
Blaszczyk J, Lu Z, Li Y, Yan H, Ji X. Crystallographic and molecular dynamics simulation analysis of Escherichia coli dihydroneopterin aldolase. Cell Biosci. 2014 Sep 02;4(1):52. doi: 10.1186/2045-3701-4-52. eCollection 2014. PMID: 25264482; PMCID: PMC4176595.
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Red cell allo- and autoimmunisation in transfused sickle cell and cancer patients in Kenyatta National Hospital, Nairobi, Kenya.

African journal of laboratory medicine

Mangare C, Mbugua A, Maturi P, Rajab J, Blasczyk R, Heuft HG.
PMID: 28879098
Afr J Lab Med. 2015 Sep 25;4(1):297. doi: 10.4102/ajlm.v4i1.297. eCollection 2015.

BACKGROUND: Currently, no data are available on the prevalence of red blood cell (RBC) antibody formation amongst Kenyan patients with multiple transfusion needs, such as patients with sickle cell disease (SCD) or haematological malignancies (HM) and solid (SM) malignancies.OBJECTIVES:...

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Mangare C, Mbugua A, Maturi P, et al. Red cell allo- and autoimmunisation in transfused sickle cell and cancer patients in Kenyatta National Hospital, Nairobi, Kenya. Afr J Lab Med. 2015;4(1):297doi: 10.4102/ajlm.v4i1.297.
Mangare, C., Mbugua, A., Maturi, P., Rajab, J., Blasczyk, R., & Heuft, H. G. (2015). Red cell allo- and autoimmunisation in transfused sickle cell and cancer patients in Kenyatta National Hospital, Nairobi, Kenya. African journal of laboratory medicine, 4(1), 297. https://doi.org/10.4102/ajlm.v4i1.297
Mangare, Caroline, et al. "Red cell allo- and autoimmunisation in transfused sickle cell and cancer patients in Kenyatta National Hospital, Nairobi, Kenya." African journal of laboratory medicine vol. 4,1 (2015): 297. doi: https://doi.org/10.4102/ajlm.v4i1.297
Mangare C, Mbugua A, Maturi P, Rajab J, Blasczyk R, Heuft HG. Red cell allo- and autoimmunisation in transfused sickle cell and cancer patients in Kenyatta National Hospital, Nairobi, Kenya. Afr J Lab Med. 2015 Sep 25;4(1):297. doi: 10.4102/ajlm.v4i1.297. eCollection 2015. PMID: 28879098; PMCID: PMC5433806.
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Towards the Manufacture of Megakaryocytes and Platelets for Clinical Application.

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie

Baigger A, Blasczyk R, Figueiredo C.
PMID: 28626367
Transfus Med Hemother. 2017 Jun;44(3):165-173. doi: 10.1159/000477261. Epub 2017 May 23.

Platelet transfusions are used in standard clinical practice to prevent hemorrhage in patients suffering from thrombocytopenia or platelet dysfunctions. Recently, a constant rise on the demand of platelets for transfusion has been registered. This may be associated with several...

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Baigger A, Blasczyk R, Figueiredo C. Towards the Manufacture of Megakaryocytes and Platelets for Clinical Application. Transfus Med Hemother. 2017;44(3):165-173doi: 10.1159/000477261.
Baigger, A., Blasczyk, R., & Figueiredo, C. (2017). Towards the Manufacture of Megakaryocytes and Platelets for Clinical Application. Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie, 44(3), 165-173. https://doi.org/10.1159/000477261
Baigger, Anja, et al. "Towards the Manufacture of Megakaryocytes and Platelets for Clinical Application." Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie vol. 44,3 (2017): 165-173. doi: https://doi.org/10.1159/000477261
Baigger A, Blasczyk R, Figueiredo C. Towards the Manufacture of Megakaryocytes and Platelets for Clinical Application. Transfus Med Hemother. 2017 Jun;44(3):165-173. doi: 10.1159/000477261. Epub 2017 May 23. PMID: 28626367; PMCID: PMC5473071.
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Antithrombotic therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention, including compliance with current guidelines-data from the POLish Atrial Fibrillation (POL-AF) Registry.

Cardiovascular diagnosis and therapy

Uziębło-Życzkowska B, Krzesiński P, Maciorowska M, Gorczyca I, Jelonek O, Wójcik M, Błaszczyk R, Kapłon-Cieślicka A, Gawałko M, Tokarek T, Rajtar-Salwa R, Bil J, Wojewódzki M, Szpotowicz A, Krzciuk M, Bednarski J, Bakuła-Ostalska E, Tomaszuk-Kazberuk A, Szyszkowska A, Wełnicki M, Mamcarz A, Wożakowska-Kapłon B.
PMID: 33708474
Cardiovasc Diagn Ther. 2021 Feb;11(1):14-27. doi: 10.21037/cdt-20-839.

BACKGROUND: Although triple antithrombotic therapy (TAT) is recommended in patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI), guidelines allow an option of dual antithrombotic therapy (DAT). This study assesses the everyday practice of 10 cardiology departments in...

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Uziębło-Życzkowska B, Krzesiński P, Maciorowska M, et al. Antithrombotic therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention, including compliance with current guidelines-data from the POLish Atrial Fibrillation (POL-AF) Registry. Cardiovasc Diagn Ther. 2021;11(1):14-27doi: 10.21037/cdt-20-839.
Uziębło-Życzkowska, B., Krzesiński, P., Maciorowska, M., Gorczyca, I., Jelonek, O., Wójcik, M., Błaszczyk, R., Kapłon-Cieślicka, A., Gawałko, M., Tokarek, T., Rajtar-Salwa, R., Bil, J., Wojewódzki, M., Szpotowicz, A., Krzciuk, M., Bednarski, J., Bakuła-Ostalska, E., Tomaszuk-Kazberuk, A., Szyszkowska, A., Wełnicki, M., Mamcarz, A., & Wożakowska-Kapłon, B. (2021). Antithrombotic therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention, including compliance with current guidelines-data from the POLish Atrial Fibrillation (POL-AF) Registry. Cardiovascular diagnosis and therapy, 11(1), 14-27. https://doi.org/10.21037/cdt-20-839
Uziębło-Życzkowska, Beata, et al. "Antithrombotic therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention, including compliance with current guidelines-data from the POLish Atrial Fibrillation (POL-AF) Registry." Cardiovascular diagnosis and therapy vol. 11,1 (2021): 14-27. doi: https://doi.org/10.21037/cdt-20-839
Uziębło-Życzkowska B, Krzesiński P, Maciorowska M, Gorczyca I, Jelonek O, Wójcik M, Błaszczyk R, Kapłon-Cieślicka A, Gawałko M, Tokarek T, Rajtar-Salwa R, Bil J, Wojewódzki M, Szpotowicz A, Krzciuk M, Bednarski J, Bakuła-Ostalska E, Tomaszuk-Kazberuk A, Szyszkowska A, Wełnicki M, Mamcarz A, Wożakowska-Kapłon B. Antithrombotic therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention, including compliance with current guidelines-data from the POLish Atrial Fibrillation (POL-AF) Registry. Cardiovasc Diagn Ther. 2021 Feb;11(1):14-27. doi: 10.21037/cdt-20-839. PMID: 33708474; PMCID: PMC7944221.
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Genetic Modification of Limbal Stem Cells to Decrease Allogeneic Immune Responses.

Frontiers in immunology

Valdivia E, Bertolin M, Breda C, Carvalho Oliveira M, Salz AK, Hofmann N, Börgel M, Blasczyk R, Ferrari S, Figueiredo C.
PMID: 34956181
Front Immunol. 2021 Dec 09;12:747357. doi: 10.3389/fimmu.2021.747357. eCollection 2021.

Limbal stem cell (LSC) transplantation is the only efficient treatment for patients affected by LSC deficiency (LSCD). Allogeneic LSC transplantation is one of the most successful alternative for patients with bilateral LSCD. Nevertheless, the high variability of the human...

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Valdivia E, Bertolin M, Breda C, et al. Genetic Modification of Limbal Stem Cells to Decrease Allogeneic Immune Responses. Front Immunol. 2021;12:747357doi: 10.3389/fimmu.2021.747357.
Valdivia, E., Bertolin, M., Breda, C., Carvalho Oliveira, M., Salz, A. K., Hofmann, N., Börgel, M., Blasczyk, R., Ferrari, S., & Figueiredo, C. (2021). Genetic Modification of Limbal Stem Cells to Decrease Allogeneic Immune Responses. Frontiers in immunology, 12747357. https://doi.org/10.3389/fimmu.2021.747357
Valdivia, Emilio, et al. "Genetic Modification of Limbal Stem Cells to Decrease Allogeneic Immune Responses." Frontiers in immunology vol. 12 (2021): 747357. doi: https://doi.org/10.3389/fimmu.2021.747357
Valdivia E, Bertolin M, Breda C, Carvalho Oliveira M, Salz AK, Hofmann N, Börgel M, Blasczyk R, Ferrari S, Figueiredo C. Genetic Modification of Limbal Stem Cells to Decrease Allogeneic Immune Responses. Front Immunol. 2021 Dec 09;12:747357. doi: 10.3389/fimmu.2021.747357. eCollection 2021. PMID: 34956181; PMCID: PMC8696204.
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Genetic Modification of Limbs Using .

Human gene therapy

Valdivia E, Rother T, Yuzefovych Y, Hack F, Wenzel N, Blasczyk R, Krezdorn N, Figueiredo C.
PMID: 34779223
Hum Gene Ther. 2022 Jan 06; doi: 10.1089/hum.2021.199. Epub 2022 Jan 06.

Genetic engineering is a promising tool to repair genetic disorders, improve graft function, or reduce immune responses toward allografts.

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Valdivia E, Rother T, Yuzefovych Y, et al. Genetic Modification of Limbs Using . Hum Gene Ther. 2022;doi: 10.1089/hum.2021.199.
Valdivia, E., Rother, T., Yuzefovych, Y., Hack, F., Wenzel, N., Blasczyk, R., Krezdorn, N., & Figueiredo, C. (2022). Genetic Modification of Limbs Using . Human gene therapy, . https://doi.org/10.1089/hum.2021.199
Valdivia, Emilio, et al. "Genetic Modification of Limbs Using ." Human gene therapy vol. (2022). doi: https://doi.org/10.1089/hum.2021.199
Valdivia E, Rother T, Yuzefovych Y, Hack F, Wenzel N, Blasczyk R, Krezdorn N, Figueiredo C. Genetic Modification of Limbs Using . Hum Gene Ther. 2022 Jan 06; doi: 10.1089/hum.2021.199. Epub 2022 Jan 06. PMID: 34779223.
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