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Showing 1 to 12 of 15 entries
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Sulfur-Containing Monoterpenoids as Potential Antithrombotic Drugs: Research in the Molecular Mechanism of Coagulation Activity Using Pinanyl Sulfoxide as an Example.

Frontiers in pharmacology

Nikitina LE, Kiselev SV, Startseva VA, Bodrov AV, Azizova ZR, Shipina OT, Fedyunina IV, Boichuk SV, Lodochnikova OA, Klochkov VV, Galiullina LF, Khaliullina AV.
PMID: 29515444
Front Pharmacol. 2018 Feb 19;9:116. doi: 10.3389/fphar.2018.00116. eCollection 2018.

In this article we present the synthesis of enantiomerically pure sulfoxide and study the influence of this compound on hemostasis. Detailed NMR studies and molecular dynamics simulations using sodium dodecyl sulfate (SDS) membrane models indicated that the bicyclic fragment...

Necessity of flow cytometry assessment of circulating plasma cells and its connection with clinical characteristics of primary and secondary plasma cell leukaemia.

British journal of haematology

Bezdekova R, Jelinek T, Kralova R, Stork M, Polackova P, Vsianska P, Brozova L, Jarkovsky J, Almasi M, Boichuk I, Knechtova Z, Penka M, Pour L, Sevcikova S, Hajek R, Rihova L.
PMID: 34500493
Br J Haematol. 2021 Oct;195(1):95-107. doi: 10.1111/bjh.17713. Epub 2021 Sep 09.

Plasma cell leukaemia (PCL) is a rare and very aggressive plasma cell disorder. Preventing a dismal outcome of PCL requires early diagnosis with appropriate analytical tools. Therefore, the investigation of 33 patients with primary and secondary PCL was done...

Radiomics of Liver Metastases: A Systematic Review.

Cancers

Fiz F, ViganĂ² L, Gennaro N, Costa G, La Bella L, Boichuk A, Cavinato L, Sollini M, Politi LS, Chiti A, Torzilli G.
PMID: 33036490
Cancers (Basel). 2020 Oct 07;12(10). doi: 10.3390/cancers12102881.

Multidisciplinary management of patients with liver metastases (LM) requires a precision medicine approach, based on adequate profiling of tumor biology and robust biomarkers. Radiomics, defined as the high-throughput identification, analysis, and translational applications of radiological textural features, could fulfill...

Inhibition of FGF2-Mediated Signaling in GIST-Promising Approach for Overcoming Resistance to Imatinib.

Cancers

Boichuk S, Galembikova A, Mikheeva E, Bikinieva F, Aukhadieva A, Dunaev P, Khalikov D, Petrov S, Kurtasanov R, Valeeva E, Kireev I, Dugina V, Lushnikova A, Novikova M, Kopnin P.
PMID: 32599808
Cancers (Basel). 2020 Jun 24;12(6). doi: 10.3390/cancers12061674.

Inhibition of KIT-signaling is a major molecular target for gastrointestinal stromal tumor (GIST) therapy, and imatinib mesylate (IM) is known as the most effective first-line treatment option for patients with advanced, unresectable, and/or metastatic GISTs. We show here for...

Influence of Musculoskeletal System Dysfunction Degree on Psychophysiological Indicators of Paralympic Athletes.

Sports (Basel, Switzerland)

Kozina Z, Lytovchenko M, Safronov D, Boichuk Y, Chaika O, Shepelenko T, Polianskyi A, Protsevskiy V, Peretyaha L, Konnova M.
PMID: 30813593
Sports (Basel). 2019 Feb 26;7(3). doi: 10.3390/sports7030055.

The purpose of the work was to identify the influence of functional class and degree of damage to extremities on psychophysiological indicators of Paralympians. The study involved 33 elite athletes with musculoskeletal system disorders of the 6 (

Gut-Associated Plasmacytoid Dendritic Cells Display an Immature Phenotype and Upregulated Granzyme B in Subjects with HIV/AIDS.

Frontiers in immunology

Boichuk SV, Khaiboullina SF, Ramazanov BR, Khasanova GR, Ivanovskaya KA, Nizamutdinov EZ, Sharafutdinov MR, Martynova EV, DeMeirleir KL, Hulstaert J, Anokhin VA, Rizvanov AA, Lombardi VC.
PMID: 26441989
Front Immunol. 2015 Sep 24;6:485. doi: 10.3389/fimmu.2015.00485. eCollection 2015.

Plasmacytoid dendritic cells (pDCs) in the periphery of subjects with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) decrease over time, and the fate of these cells has been the subject of ongoing investigation. Previous studies using animal models as...

Regulation of the radionuclide content in commodities produced in areas affected by the Chornobyl accident.

Problemy radiatsiinoi medytsyny ta radiobiolohii

Berkovskyy VB, Ratia GG, Masiuk SV, Bonchuk YV, Gerasimenko VB, Aryasov PB, Treskunova TV, Zhadan NS, Ivanova OM, Boyko ZN.
PMID: 25536545
Probl Radiac Med Radiobiol. 2014 Sep;19:26-34.

This paper discusses the approaches to regulation of the content of radionuclides in commodities and compares the international and Ukrainian standards, which establish permissible levels of the content of radionuclides in food-stuffs produced in the Chornobyl-affected areas. The paper...

Contrast Administration Impacts CT-Based Radiomics of Colorectal Liver Metastases and Non-Tumoral Liver Parenchyma Revealing the "Radiological" Tumour Microenvironment.

Diagnostics (Basel, Switzerland)

Fiz F, Costa G, Gennaro N, la Bella L, Boichuk A, Sollini M, Politi LS, Balzarini L, Torzilli G, Chiti A, ViganĂ² L.
PMID: 34202253
Diagnostics (Basel). 2021 Jun 25;11(7). doi: 10.3390/diagnostics11071162.

The impact of the contrast medium on the radiomic textural features (TF) extracted from the CT scan is unclear. We investigated the modification of TFs of colorectal liver metastases (CLM), peritumoral tissue, and liver parenchyma. One hundred and sixty-two...

Liquid-Gated Two-Layer Silicon Nanowire FETs: Evidence of Controlling Single-Trap Dynamic Processes.

Nano letters

Kutovyi Y, Zadorozhnyi I, Handziuk V, Hlukhova H, Boichuk N, Petrychuk M, Vitusevich S.
PMID: 30346789
Nano Lett. 2018 Nov 14;18(11):7305-7313. doi: 10.1021/acs.nanolett.8b03508. Epub 2018 Oct 26.

We fabricate two-layer (TL) silicon nanowires (NW) field-effect transistors (FETs) with a liquid gate. The NW devices show advanced characteristics, which reflect reliable single-electron phenomena. A strong modulation effect of channel conductivity with effectively tuned parameters is revealed. The...

Establishment and characterization of a triple negative basal-like breast cancer cell line with multi-drug resistance.

Oncology letters

Boichuk S, Galembikova A, Sitenkov A, Khusnutdinov R, Dunaev P, Valeeva E, Usolova N.
PMID: 29085518
Oncol Lett. 2017 Oct;14(4):5039-5045. doi: 10.3892/ol.2017.6795. Epub 2017 Aug 23.

Triple-negative breast carcinoma (TNBC) is one of the most aggressive subtypes of breast cancer and is associated with an unfavorable prognosis. The management of TNBC is currently based on the use of classical cytotoxic drugs, i.e., anthracyclines and/or microtubule-binding...

Conditional median-based Bayesian growth mixture modeling for nonnormal data.

Behavior research methods

Kim S, Tong X, Zhou J, Boichuk JP.
PMID: 34590287
Behav Res Methods. 2021 Sep 29; doi: 10.3758/s13428-021-01655-w. Epub 2021 Sep 29.

Growth mixture modeling is a common tool for longitudinal data analysis. One of the key assumptions of traditional growth mixture modeling is that repeated measures within each class are normally distributed. When this normality assumption is violated, traditional growth...

Activation-relaxation processes and related effects in quantum conductance of molecular junctions.

Nanotechnology

Gasparyan F, Boichuk N, Vitusevich S.
PMID: 31610534
Nanotechnology. 2020 Jan 17;31(4):045001. doi: 10.1088/1361-6528/ab4d96. Epub 2019 Oct 14.

We reveal the comparative relationship between small changes in quantum conductivity behavior for molecular junctions. We clarify the mechanisms of acquiring and losing additional thermal activation energy during average current flow in a gold-1,4 benzenediamine (BDA)-gold molecular junction and...

Showing 1 to 12 of 15 entries