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Editorial.

Bioorganic & medicinal chemistry letters

Boger DL.
PMID: 26343827
Bioorg Med Chem Lett. 2015 Nov 01;25(21):4713. doi: 10.1016/j.bmcl.2015.08.082. Epub 2015 Sep 01.

No abstract available.

Predicting amyloid status in corticobasal syndrome using modified clinical criteria, magnetic resonance imaging and fluorodeoxyglucose positron emission tomography.

Alzheimer's research & therapy

Sha SJ, Ghosh PM, Lee SE, Corbetta-Rastelli C, Jagust WJ, Kornak J, Rankin KP, Grinberg LT, Vinters HV, Mendez MF, Dickson DW, Seeley WW, Gorno-Tempini M, Kramer J, Miller BL, Boxer AL, Rabinovici GD.
PMID: 25733984
Alzheimers Res Ther. 2015 Mar 02;7(1):8. doi: 10.1186/s13195-014-0093-y. eCollection 2015.

INTRODUCTION: Group comparisons demonstrate greater visuospatial and memory deficits and temporoparietal-predominant degeneration on neuroimaging in patients with corticobasal syndrome (CBS) found to have Alzheimer's disease (AD) pathology versus those with underlying frontotemporal lobar degeneration (FTLD). The value of these...

Whole-Genome Sequences of 80 Environmental and Clinical Isolates of Burkholderia pseudomallei.

Genome announcements

Johnson SL, Baker AL, Chain PS, Currie BJ, Daligault HE, Davenport KW, Davis CB, Inglis TJ, Kaestli M, Koren S, Mayo M, Merritt AJ, Price EP, Sarovich DS, Warner J, Rosovitz MJ.
PMID: 25676747
Genome Announc. 2015 Feb 12;3(1). doi: 10.1128/genomeA.01282-14.

Here, we present the draft genome sequences of 80 isolates of Burkholderia pseudomallei. The isolates represent clinical cases of melioidosis and environmental isolates from regions in Australia and Papua New Guinea where B. pseudomallei is endemic. The genomes provide...

Single-component white-light emission via intramolecular electronic conjugation-truncation with perylenemonoimide.

Chemical communications (Cambridge, England)

Pal K, Sharma V, Koner AL.
PMID: 28569893
Chem Commun (Camb). 2017 Jul 11;53(56):7909-7912. doi: 10.1039/c7cc02873c.

Solvent specific intramolecular electronic communication truncated optical behaviour, and white light emission with a CIE chromaticity index of (0.33, 0.33) using only a single component via non-covalent nano-assembly of alkyne-phenanthrene conjugated perylenemonoimide (PMIAP) are demonstrated.

Who is More Likely to Use the Internet for Health Behavior Change? A Cross-Sectional Survey of Internet Use Among Smokers and Nonsmokers Who Are Orthopedic Trauma Patients.

JMIR mental health

McCrabb S, Baker AL, Attia J, Balogh ZJ, Lott N, Palazzi K, Naylor J, Harris IA, Doran C, George J, Wolfenden L, Skelton E, Bonevski B.
PMID: 28559228
JMIR Ment Health. 2017 May 30;4(2):e18. doi: 10.2196/mental.7435.

BACKGROUND: eHealth presents opportunities to provide population groups with accessible health interventions, although knowledge about Internet access, peoples' interest in using the Internet for health, and users' characteristics are required prior to eHealth program development.OBJECTIVE: This study surveyed hospital...

The primary health care physician and the cancer patient: tips and strategies for managing sexual health.

Translational andrology and urology

Zhou ES, Nekhlyudov L, Bober SL.
PMID: 26816826
Transl Androl Urol. 2015 Apr;4(2):218-31. doi: 10.3978/j.issn.2223-4683.2014.11.07.

There is a large and growing population of long-term cancer survivors. Primary care physicians (PCPs) are playing an increasingly greater role in the care of these patients across the continuum of cancer survivorship. In this role, PCPs are faced...

Total Synthesis of Quinoxapeptin A-C: Establishment of Absolute Stereochemistry.

Angewandte Chemie (International ed. in English)

Boger DL, Ledeboer MW, Kume M, Jin Q.
PMID: 10458810
Angew Chem Int Ed Engl. 1999 Aug;38(16):2424-2426. doi: 10.1002/(sici)1521-3773(19990816)38:16<2424::aid-anie2424>3.0.co;2-9.

The relative and absolute stereochemistry of the naturally occurring potent HIV reverse transcriptase (RT) inhibitors 1 and 2, quinoxapeptin A and B, were established by total synthesis. Their synthetic precursor 3 (dubbed quinoxapeptin C) was found to be a...

Are the Duocarmycin and CC-1065 DNA Alkylation Reactions Acid-Catalyzed? Solvolysis pH-Rate Profiles Suggest They Are Not.

The Journal of organic chemistry

Boger DL, Garbaccio RM.
PMID: 11674637
J Org Chem. 1999 Jul 23;64(15):5666-5669. doi: 10.1021/jo990762g.

A study of the solvolysis pH-rate profiles for two key reactive CC-1065/duocarmycin alkylation subunit analogues is detailed. Unlike the authentic alkylation subunits and N-BOC-CBI (4) which are too stable to establish complete solvolysis pH-rate profiles, the analogues N-BOC-CBQ (5)...

CC-1065 and the Duocarmycins: Synthetic Studies.

Chemical reviews

Boger DL, Boyce CW, Garbaccio RM, Goldberg JA.
PMID: 11848889
Chem Rev. 1997 May 08;97(3):787-828. doi: 10.1021/cr960095g.

No abstract available.

Mantoux reaction survey conducted in the northern region of Saudi Arabia.

Annals of Saudi medicine

Al-Kassimi F, Abdullah A, Al-Orainey I, Al-Hajjaj M, Abdul Baghee EA, Baner AB.
PMID: 17588111
Ann Saudi Med. 1991 May;11(3):315-21. doi: 10.5144/0256-4947.1991.315.

A nationwide epidemiological survey is under way to assess the prevalence of tuberculosis infection in the inhabitants of Saudi Arabia. The assessment tools include the Mantoux test and culturing of sputum samples obtained from inhabitants of the five regions...

Histochemical characterization of collagen fibers in fibrous overgrowth (irritation fibroma) of the oral mucosa: effect of age and duration of lesion.

Archives of gerontology and geriatrics

Dayan D, Bodner L, Hammel I, Wolman M.
PMID: 15374313
Arch Gerontol Geriatr. 1994 Jan-Feb;18(1):53-7. doi: 10.1016/0167-4943(94)90047-7.

In a study of 43 specimens of oral mucosa irritation fibroma, polarization colours of collagen thin (0.8 microm) and thick (1.6-2.4 microm) fibers were recorded in formalin-fixed and paraffin-embedded sections stained with Picrosirius red. Examination of polarization colours of...

3-hydroxyacyl-coenzyme a dehydrogenase deficiency: identification of a new mutation causing hyperinsulinemic hypoketotic hypoglycemia, altered organic acids and acylcarnitines concentrations.

JIMD reports

Popa FI, Perlini S, Teofoli F, Degani D, Funghini S, La Marca G, Rinaldo P, Vincenzi M, Antoniazzi F, Boner A, Camilot M.
PMID: 23430856
JIMD Rep. 2012;2:71-7. doi: 10.1007/8904_2011_50. Epub 2011 Sep 06.

The human HADH gene encodes the short-chain-L-3-hydroxyacyl-CoA dehydrogenase, the enzyme which catalyzes the third step of the β-oxidation of the fatty acids in the mitochondrial matrix. Loss-of-function mutations in the HADH gene lead to short-chain-L-3-hydroxyacyl-CoA dehydrogenase deficiency, an autosomal...

Showing 1 to 12 of 312 entries