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Showing 1 to 12 of 59 entries
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Measurement of dynamic cell-induced 3D displacement fields .

Biomedical optics express

Mulligan JA, Bordeleau F, Reinhart-King CA, Adie SG.
PMID: 28271010
Biomed Opt Express. 2017 Jan 27;8(2):1152-1171. doi: 10.1364/BOE.8.001152. eCollection 2017 Feb 01.

Traction force microscopy (TFM) is a method used to study the forces exerted by cells as they sense and interact with their environment. Cell forces play a role in processes that take place over a wide range of spatiotemporal...

Development and validation of a brief screening instrument for psychosocial risk associated with genetic testing: a pan-Canadian cohort study.

BMJ open

Esplen MJ, Cappelli M, Wong J, Bottorff JL, Hunter J, Carroll J, Dorval M, Wilson B, Allanson J, Semotiuk K, Aronson M, Bordeleau L, Charlemagne N, Meschino W.
PMID: 23485718
BMJ Open. 2013 Mar 13;3(3). doi: 10.1136/bmjopen-2012-002227.

OBJECTIVES: To develop a brief, reliable and valid instrument to screen psychosocial risk among those who are undergoing genetic testing for Adult-Onset Hereditary Disease (AOHD).DESIGN: A prospective two-phase cohort study.SETTING: 5 genetic testing centres for AOHD, such as cancer,...

Diversity of integrating conjugative elements in actinobacteria: Coexistence of two mechanistically different DNA-translocation systems.

Mobile genetic elements

Bordeleau E, Ghinet MG, Burrus V.
PMID: 22934248
Mob Genet Elements. 2012 Mar 01;2(2):119-124. doi: 10.4161/mge.20498.

Conjugation is certainly the most widespread and promiscuous mechanism of horizontal gene transfer in bacteria. During conjugation, DNA translocation across membranes of two cells forming a mating pair is mediated by two types of mobile genetic elements: conjugative plasmids...

Agreement Analysis between Vive and Vicon Systems to Monitor Lumbar Postural Changes.

Sensors (Basel, Switzerland)

van der Veen SM, Bordeleau M, Pidcoe PE, France CR, Thomas JS.
PMID: 31438520
Sensors (Basel). 2019 Aug 21;19(17). doi: 10.3390/s19173632.

Immersive virtual reality has recently developed into a readily available system that allows for full-body tracking. Can this affordable system be used for component tracking to advance or replace expensive kinematic systems for motion analysis in the clinic? The...

Clinical doses of radiation reduce collagen matrix stiffness.

APL bioengineering

Miller JP, Borde BH, Bordeleau F, Zanotelli MR, LaValley DJ, Parker DJ, Bonassar LJ, Pannullo SC, Reinhart-King CA.
PMID: 31069314
APL Bioeng. 2018 Apr 03;2(3):031901. doi: 10.1063/1.5018327. eCollection 2018 Sep.

Cells receive mechanical cues from their extracellular matrix (ECM), which direct migration, differentiation, apoptosis, and in some cases, the transition to a cancerous phenotype. As a result, there has been significant research to develop methods to tune the mechanical...

Origin and formation of the royal fat body of the higher termite queens.

Journal of morphology

Han SH, Bordereau C.
PMID: 30089346
J Morphol. 1982 Jul;173(1):17-28. doi: 10.1002/jmor.1051730103.

The formation of the royal fat body was studied by electron microscopy in three species of higher termites (Macrotermes bellicosus, Macrotermes subhyalinus, and Cubitermes fungifaber). The swarming alate imago has a storage fat body typical of most insects. In...

Classification of Qualitative Fieldnotes Collected During Quantitative Sensory Testing: A Step Towards the Development of a New Mixed Methods Approach in Pain Research.

Journal of pain research

Bordeleau M, Léonard G, Gauthier L, Ferland CE, Backonja M, Vollert J, Marchand S, Jackson P, Cantin L, Prud'Homme M.
PMID: 34434059
J Pain Res. 2021 Aug 18;14:2501-2511. doi: 10.2147/JPR.S301655. eCollection 2021.

PURPOSE: Quantitative sensory testing (QST) is a standardized method to assess somatosensory function. The collection of qualitative information, during the QST procedure, could be an interesting way to facilitate the characterization of altered sensory perception and the identification of...

Remote, proactive, telephone based management of toxicity in outpatients during adjuvant or neoadjuvant chemotherapy for early stage breast cancer: pragmatic, cluster randomised trial.

BMJ (Clinical research ed.)

Krzyzanowska MK, Julian JA, Gu CS, Powis M, Li Q, Enright K, Howell D, Earle CC, Gandhi S, Rask S, Brezden-Masley C, Dent S, Hajra L, Freeman O, Spadafora S, Hamm C, Califaretti N, Trudeau M, Levine MN, Amir E, Bordeleau L, Chiarotto JA, Elser C, Husain J, Laferriere N, Rahim Y, Robinson AG, Vandenberg T, Grunfeld E.
PMID: 34880055
BMJ. 2021 Dec 08;375:e066588. doi: 10.1136/bmj-2021-066588.

OBJECTIVE: To evaluate the effectiveness of remote proactive management of toxicities during chemotherapy for early stage breast cancer.DESIGN: Pragmatic, cluster randomised trial.SETTING: 20 cancer centres in Ontario, Canada, allocated by covariate constrained randomisation to remote management of toxicities or...

An evaluation of memory and attention in BRCA mutation carriers using an online cognitive assessment tool.

Cancer

Kotsopoulos J, Kim SJ, Armel S, Bordeleau L, Foulkes WD, McKinnon W, Panchal S, Cohen SA, Sun S, Sun P, McKetton L, Troyer AK, Narod SA.
PMID: 34077552
Cancer. 2021 Sep 01;127(17):3183-3193. doi: 10.1002/cncr.33654. Epub 2021 Jun 02.

BACKGROUND: The objective of this study was to evaluate the impact of various surgical, hormonal, and lifestyle factors on memory and attention in women with a BRCA1 or BRCA2 mutation.METHODS: BRCA mutation carriers enrolled in a longitudinal study were...

Author Correction: Energetic costs regulated by cell mechanics and confinement are predictive of migration path during decision-making.

Nature communications

Zanotelli MR, Rahman-Zaman A, VanderBurgh JA, Taufalele PV, Jain A, Erickson D, Bordeleau F, Reinhart-King CA.
PMID: 31797873
Nat Commun. 2019 Dec 04;10(1):5619. doi: 10.1038/s41467-019-13655-8.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Neuropathobiology of COVID-19: The Role for Glia.

Frontiers in cellular neuroscience

Tremblay ME, Madore C, Bordeleau M, Tian L, Verkhratsky A.
PMID: 33304243
Front Cell Neurosci. 2020 Nov 11;14:592214. doi: 10.3389/fncel.2020.592214. eCollection 2020.

SARS-CoV-2, which causes the Coronavirus Disease 2019 (COVID-19) pandemic, has a brain neurotropism through binding to the receptor angiotensin-converting enzyme 2 expressed by neurones and glial cells, including astrocytes and microglia. Systemic infection which accompanies severe cases of COVID-19...

National Cancer Institute Breast Cancer Steering Committee Working Group Report on Meaningful and Appropriate End Points for Clinical Trials in Metastatic Breast Cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Seidman AD, Bordeleau L, Fehrenbacher L, Barlow WE, Perlmutter J, Rubinstein L, Wedam SB, Hershman DL, Hayes JF, Butler LP, Smith ML, Regan MM, Beaver JA, Amiri-Kordestani L, Rastogi P, Zujewski JA, Korde LA.
PMID: 30212295
J Clin Oncol. 2018 Nov 10;36(32):3259-3268. doi: 10.1200/JCO.18.00242. Epub 2018 Sep 13.

PURPOSE: To provide evidence-based consensus recommendations on choice of end points for clinical trials in metastatic breast cancer, with a focus on biologic subtype and line of therapy.METHODS: The National Cancer Institute Breast Cancer Steering Committee convened a working...

Showing 1 to 12 of 59 entries