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Study of Serum Total PSA and Free PSA as an Oncological Marker in Breast Tumour.

Journal of clinical and diagnostic research : JCDR

Jahir ET, Devi R, Borthakur BB.
PMID: 28511371
J Clin Diagn Res. 2017 Mar;11(3):BC13-BC16. doi: 10.7860/JCDR/2017/22111.9543. Epub 2017 Mar 01.

INTRODUCTION: Breast Cancer (BC) cases are rising alarmingly all over the world and India is not an exception. This rising trend is due to an increased age at first child birth, decreased breast feeding, and the changing lifestyle mostly...

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Jahir ET, Devi R, Borthakur BB. Study of Serum Total PSA and Free PSA as an Oncological Marker in Breast Tumour. J Clin Diagn Res. 2017;11(3):BC13-BC16doi: 10.7860/JCDR/2017/22111.9543.
Jahir, E. T., Devi, R., & Borthakur, B. B. (2017). Study of Serum Total PSA and Free PSA as an Oncological Marker in Breast Tumour. Journal of clinical and diagnostic research : JCDR, 11(3), BC13-BC16. https://doi.org/10.7860/JCDR/2017/22111.9543
Jahir, Elteza Tahjiba, et al. "Study of Serum Total PSA and Free PSA as an Oncological Marker in Breast Tumour." Journal of clinical and diagnostic research : JCDR vol. 11,3 (2017): BC13-BC16. doi: https://doi.org/10.7860/JCDR/2017/22111.9543
Jahir ET, Devi R, Borthakur BB. Study of Serum Total PSA and Free PSA as an Oncological Marker in Breast Tumour. J Clin Diagn Res. 2017 Mar;11(3):BC13-BC16. doi: 10.7860/JCDR/2017/22111.9543. Epub 2017 Mar 01. PMID: 28511371; PMCID: PMC5427297.
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Relationship of on Admission Hypocalcaemia and Illness Severity as Measured by APACHE-II and SOFA Score in Intensive Care Patients'.

Journal of clinical and diagnostic research : JCDR

Dey S, Karim HMR, Yunus M, Barman A, Bhattacharyya P, Borthakur MP.
PMID: 28511481
J Clin Diagn Res. 2017 Mar;11(3):UC01-UC03. doi: 10.7860/JCDR/2017/22895.9402. Epub 2017 Mar 01.

INTRODUCTION: Hypocalcaemia is very much prevalent in critically ill patients yet very less is known about its association with severity of illness. Acute Physiology and Chronic Health Evaluation (APACHE) and Sequential Organ Failure Assessment (SOFA) are two commonly used...

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Dey S, Karim HMR, Yunus M, et al. Relationship of on Admission Hypocalcaemia and Illness Severity as Measured by APACHE-II and SOFA Score in Intensive Care Patients'. J Clin Diagn Res. 2017;11(3):UC01-UC03doi: 10.7860/JCDR/2017/22895.9402.
Dey, S., Karim, H. M. R., Yunus, M., Barman, A., Bhattacharyya, P., & Borthakur, M. P. (2017). Relationship of on Admission Hypocalcaemia and Illness Severity as Measured by APACHE-II and SOFA Score in Intensive Care Patients'. Journal of clinical and diagnostic research : JCDR, 11(3), UC01-UC03. https://doi.org/10.7860/JCDR/2017/22895.9402
Dey, Samarjit, et al. "Relationship of on Admission Hypocalcaemia and Illness Severity as Measured by APACHE-II and SOFA Score in Intensive Care Patients'." Journal of clinical and diagnostic research : JCDR vol. 11,3 (2017): UC01-UC03. doi: https://doi.org/10.7860/JCDR/2017/22895.9402
Dey S, Karim HMR, Yunus M, Barman A, Bhattacharyya P, Borthakur MP. Relationship of on Admission Hypocalcaemia and Illness Severity as Measured by APACHE-II and SOFA Score in Intensive Care Patients'. J Clin Diagn Res. 2017 Mar;11(3):UC01-UC03. doi: 10.7860/JCDR/2017/22895.9402. Epub 2017 Mar 01. PMID: 28511481; PMCID: PMC5427407.
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Impact of the number of mutations in survival and response outcomes to hypomethylating agents in patients with myelodysplastic syndromes or myelodysplastic/myeloproliferative neoplasms.

Oncotarget

Montalban-Bravo G, Takahashi K, Patel K, Wang F, Xingzhi S, Nogueras GM, Huang X, Pierola AA, Jabbour E, Colla S, Gañan-Gomez I, Borthakur G, Daver N, Estrov Z, Kadia T, Pemmaraju N, Ravandi F, Bueso-Ramos C, Chamseddine A, Konopleva M, Zhang J, Kantarjian H, Futreal A, Garcia-Manero G.
PMID: 29515765
Oncotarget. 2018 Jan 03;9(11):9714-9727. doi: 10.18632/oncotarget.23882. eCollection 2018 Feb 09.

The prognostic and predictive value of sequencing analysis in myelodysplastic syndromes (MDS) has not been fully integrated into clinical practice. We performed whole exome sequencing (WES) of bone marrow samples from 83 patients with MDS and 31 with MDS/MPN...

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Montalban-Bravo G, Takahashi K, Patel K, et al. Impact of the number of mutations in survival and response outcomes to hypomethylating agents in patients with myelodysplastic syndromes or myelodysplastic/myeloproliferative neoplasms. Oncotarget. 2018;9(11):9714-9727doi: 10.18632/oncotarget.23882.
Montalban-Bravo, G., Takahashi, K., Patel, K., Wang, F., Xingzhi, S., Nogueras, G. M., Huang, X., Pierola, A. A., Jabbour, E., Colla, S., Gañan-Gomez, I., Borthakur, G., Daver, N., Estrov, Z., Kadia, T., Pemmaraju, N., Ravandi, F., Bueso-Ramos, C., Chamseddine, A., Konopleva, M., Zhang, J., Kantarjian, H., Futreal, A., & Garcia-Manero, G. (2018). Impact of the number of mutations in survival and response outcomes to hypomethylating agents in patients with myelodysplastic syndromes or myelodysplastic/myeloproliferative neoplasms. Oncotarget, 9(11), 9714-9727. https://doi.org/10.18632/oncotarget.23882
Montalban-Bravo, Guillermo, et al. "Impact of the number of mutations in survival and response outcomes to hypomethylating agents in patients with myelodysplastic syndromes or myelodysplastic/myeloproliferative neoplasms." Oncotarget vol. 9,11 (2018): 9714-9727. doi: https://doi.org/10.18632/oncotarget.23882
Montalban-Bravo G, Takahashi K, Patel K, Wang F, Xingzhi S, Nogueras GM, Huang X, Pierola AA, Jabbour E, Colla S, Gañan-Gomez I, Borthakur G, Daver N, Estrov Z, Kadia T, Pemmaraju N, Ravandi F, Bueso-Ramos C, Chamseddine A, Konopleva M, Zhang J, Kantarjian H, Futreal A, Garcia-Manero G. Impact of the number of mutations in survival and response outcomes to hypomethylating agents in patients with myelodysplastic syndromes or myelodysplastic/myeloproliferative neoplasms. Oncotarget. 2018 Jan 03;9(11):9714-9727. doi: 10.18632/oncotarget.23882. eCollection 2018 Feb 09. PMID: 29515765; PMCID: PMC5839396.
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Histomorphological responses after therapy with pegylated interferon α-2a in patients with essential thrombocythemia (ET) and polycythemia vera (PV).

Experimental hematology & oncology

Masarova L, Yin CC, Cortes JE, Konopleva M, Borthakur G, Newberry KJ, Kantarjian HM, Bueso-Ramos CE, Verstovsek S.
PMID: 29152412
Exp Hematol Oncol. 2017 Nov 09;6:30. doi: 10.1186/s40164-017-0090-5. eCollection 2017.

BACKGROUND: Pegylated interferon alfa-2a (PEG-IFN-α-2a) is a potent immunomodulating agent capable of inducing high rate of hematologic and even complete molecular remission in patients with essential thrombocythemia (ET) and polycythemia vera (PV). We recently reported results of a phase...

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Masarova L, Yin CC, Cortes JE, et al. Histomorphological responses after therapy with pegylated interferon α-2a in patients with essential thrombocythemia (ET) and polycythemia vera (PV). Exp Hematol Oncol. 2017;6:30doi: 10.1186/s40164-017-0090-5.
Masarova, L., Yin, C. C., Cortes, J. E., Konopleva, M., Borthakur, G., Newberry, K. J., Kantarjian, H. M., Bueso-Ramos, C. E., & Verstovsek, S. (2017). Histomorphological responses after therapy with pegylated interferon α-2a in patients with essential thrombocythemia (ET) and polycythemia vera (PV). Experimental hematology & oncology, 630. https://doi.org/10.1186/s40164-017-0090-5
Masarova, Lucia, et al. "Histomorphological responses after therapy with pegylated interferon α-2a in patients with essential thrombocythemia (ET) and polycythemia vera (PV)." Experimental hematology & oncology vol. 6 (2017): 30. doi: https://doi.org/10.1186/s40164-017-0090-5
Masarova L, Yin CC, Cortes JE, Konopleva M, Borthakur G, Newberry KJ, Kantarjian HM, Bueso-Ramos CE, Verstovsek S. Histomorphological responses after therapy with pegylated interferon α-2a in patients with essential thrombocythemia (ET) and polycythemia vera (PV). Exp Hematol Oncol. 2017 Nov 09;6:30. doi: 10.1186/s40164-017-0090-5. eCollection 2017. PMID: 29152412; PMCID: PMC5679503.
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Highly regioselective synthesis of 4-tosylthiomorpholine via intramolecular cyclization of N-tethered thioalkenols.

Organic & biomolecular chemistry

Saikia AK, Deka MJ, Borthakur U.
PMID: 27762410
Org Biomol Chem. 2016 Nov 08;14(44):10489-10495. doi: 10.1039/c6ob01869f.

A one-pot, metal-free procedure has been developed for the synthesis of 4-tosylthiomorpholine from N-tethered thioalkenols via bromination, cyclization and subsequent elimination reaction in good yields. The reaction is found to be highly regioselective.

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Saikia AK, Deka MJ, Borthakur U. Highly regioselective synthesis of 4-tosylthiomorpholine via intramolecular cyclization of N-tethered thioalkenols. Org Biomol Chem. 2016;14(44):10489-10495doi: 10.1039/c6ob01869f.
Saikia, A. K., Deka, M. J., & Borthakur, U. (2016). Highly regioselective synthesis of 4-tosylthiomorpholine via intramolecular cyclization of N-tethered thioalkenols. Organic & biomolecular chemistry, 14(44), 10489-10495. https://doi.org/10.1039/c6ob01869f
Saikia, Anil K, et al. "Highly regioselective synthesis of 4-tosylthiomorpholine via intramolecular cyclization of N-tethered thioalkenols." Organic & biomolecular chemistry vol. 14,44 (2016): 10489-10495. doi: https://doi.org/10.1039/c6ob01869f
Saikia AK, Deka MJ, Borthakur U. Highly regioselective synthesis of 4-tosylthiomorpholine via intramolecular cyclization of N-tethered thioalkenols. Org Biomol Chem. 2016 Nov 08;14(44):10489-10495. doi: 10.1039/c6ob01869f. PMID: 27762410.
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Discrete differences between strains of different Rhizobium spp. for competitive nodule occupancy on beans.

World journal of microbiology & biotechnology

Gao X, Borthakur D.
PMID: 24415021
World J Microbiol Biotechnol. 1995 Nov;11(6):681-2. doi: 10.1007/BF00361016.

Rhizobium etli strain TAL182 and R. leguminosarum bv phaseoli strain 8002, both of which produce melanin pigment, were tested for their nodulation competitiveness on beans by paired inoculation with two strains which do not produce melanin: R. tropici strain...

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Gao X, Borthakur D. Discrete differences between strains of different Rhizobium spp. for competitive nodule occupancy on beans. World J Microbiol Biotechnol. 1995;11(6):681-2doi: 10.1007/BF00361016.
Gao, X., & Borthakur, D. (1995). Discrete differences between strains of different Rhizobium spp. for competitive nodule occupancy on beans. World journal of microbiology & biotechnology, 11(6), 681-2. https://doi.org/10.1007/BF00361016
Gao, X, and Borthakur, D. "Discrete differences between strains of different Rhizobium spp. for competitive nodule occupancy on beans." World journal of microbiology & biotechnology vol. 11,6 (1995): 681-2. doi: https://doi.org/10.1007/BF00361016
Gao X, Borthakur D. Discrete differences between strains of different Rhizobium spp. for competitive nodule occupancy on beans. World J Microbiol Biotechnol. 1995 Nov;11(6):681-2. doi: 10.1007/BF00361016. PMID: 24415021.
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Successful Treatment of Intracranial Hemorrhage with Recombinant Activated Factor VII in a Patient with Newly Diagnosed Acute Myeloid Leukemia: A Case Report and Review of the Literature.

Frontiers in oncology

Pemmaraju N, Sasaki K, Johnson D, Daver N, Afshar-Kharghan V, Chen M, Ahmed S, Colen RR, Kwon M, Huh Y, Borthakur G.
PMID: 25717439
Front Oncol. 2015 Feb 11;5:29. doi: 10.3389/fonc.2015.00029. eCollection 2015.

Intracranial hemorrhage (ICH) is a common complication in acute myeloid leukemia (AML) patients with an incidence rate of 6.3% (1). Bleeding disorders related to disseminated intravascular coagulation (DIC) are common complications in AML cases (2). Recombinant activated Factor VII...

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Pemmaraju N, Sasaki K, Johnson D, et al. Successful Treatment of Intracranial Hemorrhage with Recombinant Activated Factor VII in a Patient with Newly Diagnosed Acute Myeloid Leukemia: A Case Report and Review of the Literature. Front Oncol. 2015;5:29doi: 10.3389/fonc.2015.00029.
Pemmaraju, N., Sasaki, K., Johnson, D., Daver, N., Afshar-Kharghan, V., Chen, M., Ahmed, S., Colen, R. R., Kwon, M., Huh, Y., & Borthakur, G. (2015). Successful Treatment of Intracranial Hemorrhage with Recombinant Activated Factor VII in a Patient with Newly Diagnosed Acute Myeloid Leukemia: A Case Report and Review of the Literature. Frontiers in oncology, 529. https://doi.org/10.3389/fonc.2015.00029
Pemmaraju, Naveen, et al. "Successful Treatment of Intracranial Hemorrhage with Recombinant Activated Factor VII in a Patient with Newly Diagnosed Acute Myeloid Leukemia: A Case Report and Review of the Literature." Frontiers in oncology vol. 5 (2015): 29. doi: https://doi.org/10.3389/fonc.2015.00029
Pemmaraju N, Sasaki K, Johnson D, Daver N, Afshar-Kharghan V, Chen M, Ahmed S, Colen RR, Kwon M, Huh Y, Borthakur G. Successful Treatment of Intracranial Hemorrhage with Recombinant Activated Factor VII in a Patient with Newly Diagnosed Acute Myeloid Leukemia: A Case Report and Review of the Literature. Front Oncol. 2015 Feb 11;5:29. doi: 10.3389/fonc.2015.00029. eCollection 2015. PMID: 25717439; PMCID: PMC4324079.
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Phosphorylation of GSK3α/β correlates with activation of AKT and is prognostic for poor overall survival in acute myeloid leukemia patients.

BBA clinical

Ruvolo PP, Qiu Y, Coombes KR, Zhang N, Neeley ES, Ruvolo VR, Hail N, Borthakur G, Konopleva M, Andreeff M, Kornblau SM.
PMID: 26674329
BBA Clin. 2015 Jul 23;4:59-68. doi: 10.1016/j.bbacli.2015.07.001. eCollection 2015 Dec.

BACKGROUND: Acute myeloid leukemia (AML) patients with highly active AKT tend to do poorly. Cell cycle arrest and apoptosis are tightly regulated by AKT via phosphorylation of GSK3α and β isoforms which inactivates these kinases. In the current study...

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Ruvolo PP, Qiu Y, Coombes KR, et al. Phosphorylation of GSK3α/β correlates with activation of AKT and is prognostic for poor overall survival in acute myeloid leukemia patients. BBA Clin. 2015;4:59-68doi: 10.1016/j.bbacli.2015.07.001.
Ruvolo, P. P., Qiu, Y., Coombes, K. R., Zhang, N., Neeley, E. S., Ruvolo, V. R., Hail, N., Borthakur, G., Konopleva, M., Andreeff, M., & Kornblau, S. M. (2015). Phosphorylation of GSK3α/β correlates with activation of AKT and is prognostic for poor overall survival in acute myeloid leukemia patients. BBA clinical, 459-68. https://doi.org/10.1016/j.bbacli.2015.07.001
Ruvolo, Peter P, et al. "Phosphorylation of GSK3α/β correlates with activation of AKT and is prognostic for poor overall survival in acute myeloid leukemia patients." BBA clinical vol. 4 (2015): 59-68. doi: https://doi.org/10.1016/j.bbacli.2015.07.001
Ruvolo PP, Qiu Y, Coombes KR, Zhang N, Neeley ES, Ruvolo VR, Hail N, Borthakur G, Konopleva M, Andreeff M, Kornblau SM. Phosphorylation of GSK3α/β correlates with activation of AKT and is prognostic for poor overall survival in acute myeloid leukemia patients. BBA Clin. 2015 Jul 23;4:59-68. doi: 10.1016/j.bbacli.2015.07.001. eCollection 2015 Dec. PMID: 26674329; PMCID: PMC4661707.
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Sterol-side chain cleavage by fusants ofAlkaligenes foecalis andArthrobacter oxydans.

Folia microbiologica

Barthakur S, Roy MK, Ghosh AC.
PMID: 18454333
Folia Microbiol (Praha). 1997 Apr;42(2):130-2. doi: 10.1007/BF02898721.

Protoplasts of a strain ofA. foecalis incapable of utilizing beta-sitosterol as carbon source for growth were fused with protoplasts ofA. oxydans - a strain capable of complete degradation of beta-sitosterol. Five fusants showing morphology and pattern of transformation of...

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Barthakur S, Roy MK, Ghosh AC. Sterol-side chain cleavage by fusants ofAlkaligenes foecalis andArthrobacter oxydans. Folia Microbiol (Praha). 1997;42(2):130-2doi: 10.1007/BF02898721.
Barthakur, S., Roy, M. K., & Ghosh, A. C. (1997). Sterol-side chain cleavage by fusants ofAlkaligenes foecalis andArthrobacter oxydans. Folia microbiologica, 42(2), 130-2. https://doi.org/10.1007/BF02898721
Barthakur, S, et al. "Sterol-side chain cleavage by fusants ofAlkaligenes foecalis andArthrobacter oxydans." Folia microbiologica vol. 42,2 (1997): 130-2. doi: https://doi.org/10.1007/BF02898721
Barthakur S, Roy MK, Ghosh AC. Sterol-side chain cleavage by fusants ofAlkaligenes foecalis andArthrobacter oxydans. Folia Microbiol (Praha). 1997 Apr;42(2):130-2. doi: 10.1007/BF02898721. PMID: 18454333.
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Mechanical ventilator for delivery of ¹⁷O₂ in brief pulses.

The open biomedical engineering journal

Baumgardner JE, Mellon EA, Tailor DR, Mallikarjunarao K, Borthakur A, Reddy R.
PMID: 19662118
Open Biomed Eng J. 2008 Sep 24;2:57-63. doi: 10.2174/1874120700802010057.

The ¹⁷O nucleus has been used recently by several groups for magnetic resonance (MR) imaging of cerebral metabolism. Inhalational delivery of ¹⁷O(2) in very brief pulses could, in theory, have significant advantages for determination of the cerebral metabolic rate...

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Baumgardner JE, Mellon EA, Tailor DR, et al. Mechanical ventilator for delivery of ¹⁷O₂ in brief pulses. Open Biomed Eng J. 2008;2:57-63doi: 10.2174/1874120700802010057.
Baumgardner, J. E., Mellon, E. A., Tailor, D. R., Mallikarjunarao, K., Borthakur, A., & Reddy, R. (2008). Mechanical ventilator for delivery of ¹⁷O₂ in brief pulses. The open biomedical engineering journal, 257-63. https://doi.org/10.2174/1874120700802010057
Baumgardner, J E, et al. "Mechanical ventilator for delivery of ¹⁷O₂ in brief pulses." The open biomedical engineering journal vol. 2 (2008): 57-63. doi: https://doi.org/10.2174/1874120700802010057
Baumgardner JE, Mellon EA, Tailor DR, Mallikarjunarao K, Borthakur A, Reddy R. Mechanical ventilator for delivery of ¹⁷O₂ in brief pulses. Open Biomed Eng J. 2008 Sep 24;2:57-63. doi: 10.2174/1874120700802010057. PMID: 19662118; PMCID: PMC2701066.
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Genetic Analysis of Rhizobium leguminosarum bv. Phaseoli Mutants Defective in Nodulation and Nodulation Suppression.

Applied and environmental microbiology

George ML, Robert FM, Borthakur D.
PMID: 16348664
Appl Environ Microbiol. 1992 Mar;58(3):1050-3. doi: 10.1128/aem.58.3.1050-1053.1992.

Nodulation-defective rhizobia and their nodule-forming derivatives containing cloned DNA from the wild type were used to study nodulation suppression in Phaseolus vulgaris L. Non-nitrogen-fixing derivatives which formed rhizobia-containing white nodules induced partial suppression. Comparison of this with the complete...

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George ML, Robert FM, Borthakur D. Genetic Analysis of Rhizobium leguminosarum bv. Phaseoli Mutants Defective in Nodulation and Nodulation Suppression. Appl Environ Microbiol. 1992;58(3):1050-3doi: 10.1128/aem.58.3.1050-1053.1992.
George, M. L., Robert, F. M., & Borthakur, D. (1992). Genetic Analysis of Rhizobium leguminosarum bv. Phaseoli Mutants Defective in Nodulation and Nodulation Suppression. Applied and environmental microbiology, 58(3), 1050-3. https://doi.org/10.1128/aem.58.3.1050-1053.1992
George, M L, et al. "Genetic Analysis of Rhizobium leguminosarum bv. Phaseoli Mutants Defective in Nodulation and Nodulation Suppression." Applied and environmental microbiology vol. 58,3 (1992): 1050-3. doi: https://doi.org/10.1128/aem.58.3.1050-1053.1992
George ML, Robert FM, Borthakur D. Genetic Analysis of Rhizobium leguminosarum bv. Phaseoli Mutants Defective in Nodulation and Nodulation Suppression. Appl Environ Microbiol. 1992 Mar;58(3):1050-3. doi: 10.1128/aem.58.3.1050-1053.1992. PMID: 16348664; PMCID: PMC195379.
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Expression of bacterial genes in transgenic tobacco: methods, applications and future prospects.

Electronic journal of biotechnology : EJB

Jube S, Borthakur D.
PMID: 19750137
Electron J Biotechnol. 2007 Jul 15;10(3):452-467. doi: 10.2225/vol10-issue3-fulltext-4.

Tobacco is the most commonly used plant for expression of transgenes from a variety of organisms, because it is easily grown and transformed, it provides abundant amounts of fresh tissue and has a well-established cell culture system. Many bacterial...

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Jube S, Borthakur D. Expression of bacterial genes in transgenic tobacco: methods, applications and future prospects. Electron J Biotechnol. 2007;10(3):452-467doi: 10.2225/vol10-issue3-fulltext-4.
Jube, S., & Borthakur, D. (2007). Expression of bacterial genes in transgenic tobacco: methods, applications and future prospects. Electronic journal of biotechnology : EJB, 10(3), 452-467. https://doi.org/10.2225/vol10-issue3-fulltext-4
Jube, Sandro, and Borthakur, Dulal. "Expression of bacterial genes in transgenic tobacco: methods, applications and future prospects." Electronic journal of biotechnology : EJB vol. 10,3 (2007): 452-467. doi: https://doi.org/10.2225/vol10-issue3-fulltext-4
Jube S, Borthakur D. Expression of bacterial genes in transgenic tobacco: methods, applications and future prospects. Electron J Biotechnol. 2007 Jul 15;10(3):452-467. doi: 10.2225/vol10-issue3-fulltext-4. PMID: 19750137; PMCID: PMC2742426.
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