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Ca(2+)-Currents in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Effects of Two Different Culture Conditions.

Frontiers in pharmacology

Uzun AU, Mannhardt I, Breckwoldt K, Horváth A, Johannsen SS, Hansen A, Eschenhagen T, Christ T.
PMID: 27672365
Front Pharmacol. 2016 Sep 12;7:300. doi: 10.3389/fphar.2016.00300. eCollection 2016.

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) provide a unique opportunity to study human heart physiology and pharmacology and repair injured hearts. The suitability of hiPSC-CM critically depends on how closely they share physiological properties of human adult cardiomyocytes...

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Uzun AU, Mannhardt I, Breckwoldt K, et al. Ca(2+)-Currents in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Effects of Two Different Culture Conditions. Front Pharmacol. 2016;7:300doi: 10.3389/fphar.2016.00300.
Uzun, A. U., Mannhardt, I., Breckwoldt, K., Horváth, A., Johannsen, S. S., Hansen, A., Eschenhagen, T., & Christ, T. (2016). Ca(2+)-Currents in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Effects of Two Different Culture Conditions. Frontiers in pharmacology, 7300. https://doi.org/10.3389/fphar.2016.00300
Uzun, Ahmet U, et al. "Ca(2+)-Currents in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Effects of Two Different Culture Conditions." Frontiers in pharmacology vol. 7 (2016): 300. doi: https://doi.org/10.3389/fphar.2016.00300
Uzun AU, Mannhardt I, Breckwoldt K, Horváth A, Johannsen SS, Hansen A, Eschenhagen T, Christ T. Ca(2+)-Currents in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Effects of Two Different Culture Conditions. Front Pharmacol. 2016 Sep 12;7:300. doi: 10.3389/fphar.2016.00300. eCollection 2016. PMID: 27672365; PMCID: PMC5018497.
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Correlated MRI and Ultramicroscopy (MR-UM) of Brain Tumors Reveals Vast Heterogeneity of Tumor Infiltration and Neoangiogenesis in Preclinical Models and Human Disease.

Frontiers in neuroscience

Breckwoldt MO, Bode J, Sahm F, Krüwel T, Solecki G, Hahn A, Wirthschaft P, Berghoff AS, Haas M, Venkataramani V, von Deimling A, Wick W, Herold-Mende C, Heiland S, Platten M, Bendszus M, Kurz FT, Winkler F, Tews B.
PMID: 30686972
Front Neurosci. 2019 Jan 10;12:1004. doi: 10.3389/fnins.2018.01004. eCollection 2018.

Diffuse tumor infiltration into the adjacent parenchyma is an effective dissemination mechanism of brain tumors. We have previously developed correlated high field magnetic resonance imaging and ultramicroscopy (MR-UM) to study neonangiogenesis in a glioma model. In the present study...

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Breckwoldt MO, Bode J, Sahm F, et al. Correlated MRI and Ultramicroscopy (MR-UM) of Brain Tumors Reveals Vast Heterogeneity of Tumor Infiltration and Neoangiogenesis in Preclinical Models and Human Disease. Front Neurosci. 2019;12:1004doi: 10.3389/fnins.2018.01004.
Breckwoldt, M. O., Bode, J., Sahm, F., Krüwel, T., Solecki, G., Hahn, A., Wirthschaft, P., Berghoff, A. S., Haas, M., Venkataramani, V., von Deimling, A., Wick, W., Herold-Mende, C., Heiland, S., Platten, M., Bendszus, M., Kurz, F. T., Winkler, F., & Tews, B. (2018). Correlated MRI and Ultramicroscopy (MR-UM) of Brain Tumors Reveals Vast Heterogeneity of Tumor Infiltration and Neoangiogenesis in Preclinical Models and Human Disease. Frontiers in neuroscience, 121004. https://doi.org/10.3389/fnins.2018.01004
Breckwoldt, Michael O, et al. "Correlated MRI and Ultramicroscopy (MR-UM) of Brain Tumors Reveals Vast Heterogeneity of Tumor Infiltration and Neoangiogenesis in Preclinical Models and Human Disease." Frontiers in neuroscience vol. 12 (2018): 1004. doi: https://doi.org/10.3389/fnins.2018.01004
Breckwoldt MO, Bode J, Sahm F, Krüwel T, Solecki G, Hahn A, Wirthschaft P, Berghoff AS, Haas M, Venkataramani V, von Deimling A, Wick W, Herold-Mende C, Heiland S, Platten M, Bendszus M, Kurz FT, Winkler F, Tews B. Correlated MRI and Ultramicroscopy (MR-UM) of Brain Tumors Reveals Vast Heterogeneity of Tumor Infiltration and Neoangiogenesis in Preclinical Models and Human Disease. Front Neurosci. 2019 Jan 10;12:1004. doi: 10.3389/fnins.2018.01004. eCollection 2018. PMID: 30686972; PMCID: PMC6335617.
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Evolution of a concept with enzymatic debridement and autologous in situ cell and platelet-rich fibrin therapy (BroKerF).

Scars, burns & healing

Waldner M, Ismail T, Lunger A, Klein HJ, Schweizer R, Alan O, Breckwoldt T, Giovanoli P, Plock JA.
PMID: 35024172
Scars Burn Heal. 2022 Jan 06;8:20595131211052394. doi: 10.1177/20595131211052394. eCollection 2022.

BACKGROUND: Deep partial-thickness burns are traditionally treated by tangential excision and split thickness skin graft (STSG) coverage. STSGs create donor site morbidity and increase the wound surface in burn patients. Herein, we present a novel concept consisting of enzymatic...

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Waldner M, Ismail T, Lunger A, et al. Evolution of a concept with enzymatic debridement and autologous in situ cell and platelet-rich fibrin therapy (BroKerF). Scars Burn Heal. 2022;8:20595131211052394doi: 10.1177/20595131211052394.
Waldner, M., Ismail, T., Lunger, A., Klein, H. J., Schweizer, R., Alan, O., Breckwoldt, T., Giovanoli, P., & Plock, J. A. (2022). Evolution of a concept with enzymatic debridement and autologous in situ cell and platelet-rich fibrin therapy (BroKerF). Scars, burns & healing, 820595131211052394. https://doi.org/10.1177/20595131211052394
Waldner, Matthias, et al. "Evolution of a concept with enzymatic debridement and autologous in situ cell and platelet-rich fibrin therapy (BroKerF)." Scars, burns & healing vol. 8 (2022): 20595131211052394. doi: https://doi.org/10.1177/20595131211052394
Waldner M, Ismail T, Lunger A, Klein HJ, Schweizer R, Alan O, Breckwoldt T, Giovanoli P, Plock JA. Evolution of a concept with enzymatic debridement and autologous in situ cell and platelet-rich fibrin therapy (BroKerF). Scars Burn Heal. 2022 Jan 06;8:20595131211052394. doi: 10.1177/20595131211052394. eCollection 2022. PMID: 35024172; PMCID: PMC8743980.
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2021 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Neonatal Life Support; Education, Implementation, and Teams; First Aid Task Forces; and the COVID-19 Working Group.

Resuscitation

Wyckoff MH, Singletary EM, Soar J, Olasveengen TM, Greif R, Liley HG, Zideman D, Bhanji F, Andersen LW, Avis SR, Aziz K, Bendall JC, Berry DC, Borra V, Böttiger BW, Bradley R, Bray JE, Breckwoldt J, Carlson JN, Cassan P, Castrén M, Chang WT, Charlton NP, Cheng A, Chung SP, Considine J, Costa-Nobre DT, Couper K, Dainty KN, Davis PG, de Almeida MF, de Caen AR, de Paiva EF, Deakin CD, Djärv T, Douma MJ, Drennan IR, Duff JP, Eastwood KJ, El-Naggar W, Epstein JL, Escalante R, Fabres JG, Fawke J, Finn JC, Foglia EE, Folke F, Freeman K, Gilfoyle E, Goolsby CA, Grove A, Guinsburg R, Hatanaka T, Hazinski MF, Heriot GS, Hirsch KG, Holmberg MJ, Hosono S, Hsieh MJ, Hung KKC, Hsu CH, Ikeyama T, Isayama T, Kapadia VS, Kawakami MD, Kim HS, Kloeck DA, Kudenchuk PJ, Lagina AT, Lauridsen KG, Lavonas EJ, Lockey AS, Malta Hansen C, Markenson D, Matsuyama T, McKinlay CJD, Mehrabian A, Merchant RM, Meyran D, Morley PT, Morrison LJ, Nation KJ, Nemeth M, Neumar RW, Nicholson T, Niermeyer S, Nikolaou N, Nishiyama C, O'Neil BJ, Orkin AM, Osemeke O, Parr MJ, Patocka C, Pellegrino JL, Perkins GD, Perlman JM, Rabi Y, Reynolds JC, Ristagno G, Roehr CC, Sakamoto T, Sandroni C, Sawyer T, Schmölzer GM, Schnaubelt S, Semeraro F, Skrifvars MB, Smith CM, Smyth MA, Soll RF, Sugiura T, Taylor-Phillips S, Trevisanuto D, Vaillancourt C, Wang TL, Weiner GM, Welsford M, Wigginton J, Wyllie JP, Yeung J, Nolan JP, Berg KM.
PMID: 34933747
Resuscitation. 2021 Dec;169:229-311. doi: 10.1016/j.resuscitation.2021.10.040. Epub 2021 Nov 11.

The International Liaison Committee on Resuscitation initiated a continuous review of new, peer-reviewed published cardiopulmonary resuscitation science. This is the fifth annual summary of the International Liaison Committee on Resuscitation International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care...

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Wyckoff MH, Singletary EM, Soar J, et al. 2021 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Neonatal Life Support; Education, Implementation, and Teams; First Aid Task Forces; and the COVID-19 Working Group. Resuscitation. 2021;169:229-311doi: 10.1016/j.resuscitation.2021.10.040.
Wyckoff, M. H., Singletary, E. M., Soar, J., Olasveengen, T. M., Greif, R., Liley, H. G., Zideman, D., Bhanji, F., Andersen, L. W., Avis, S. R., Aziz, K., Bendall, J. C., Berry, D. C., Borra, V., Böttiger, B. W., Bradley, R., Bray, J. E., Breckwoldt, J., Carlson, J. N., Cassan, P., Castrén, M., Chang, W. T., Charlton, N. P., Cheng, A., Chung, S. P., Considine, J., Costa-Nobre, D. T., Couper, K., Dainty, K. N., Davis, P. G., de Almeida, M. F., de Caen, A. R., de Paiva, E. F., Deakin, C. D., Djärv, T., Douma, M. J., Drennan, I. R., Duff, J. P., Eastwood, K. J., El-Naggar, W., Epstein, J. L., Escalante, R., Fabres, J. G., Fawke, J., Finn, J. C., Foglia, E. E., Folke, F., Freeman, K., Gilfoyle, E., Goolsby, C. A., Grove, A., Guinsburg, R., Hatanaka, T., Hazinski, M. F., Heriot, G. S., Hirsch, K. G., Holmberg, M. J., Hosono, S., Hsieh, M. J., Hung, K. K. C., Hsu, C. H., Ikeyama, T., Isayama, T., Kapadia, V. S., Kawakami, M. D., Kim, H. S., Kloeck, D. A., Kudenchuk, P. J., Lagina, A. T., Lauridsen, K. G., Lavonas, E. J., Lockey, A. S., Malta Hansen, C., Markenson, D., Matsuyama, T., McKinlay, C. J. D., Mehrabian, A., Merchant, R. M., Meyran, D., Morley, P. T., Morrison, L. J., Nation, K. J., Nemeth, M., Neumar, R. W., Nicholson, T., Niermeyer, S., Nikolaou, N., Nishiyama, C., O'Neil, B. J., Orkin, A. M., Osemeke, O., Parr, M. J., Patocka, C., Pellegrino, J. L., Perkins, G. D., Perlman, J. M., Rabi, Y., Reynolds, J. C., Ristagno, G., Roehr, C. C., Sakamoto, T., Sandroni, C., Sawyer, T., Schmölzer, G. M., Schnaubelt, S., Semeraro, F., Skrifvars, M. B., Smith, C. M., Smyth, M. A., Soll, R. F., Sugiura, T., Taylor-Phillips, S., Trevisanuto, D., Vaillancourt, C., Wang, T. L., Weiner, G. M., Welsford, M., Wigginton, J., Wyllie, J. P., Yeung, J., Nolan, J. P., Berg, K. M. (2021). 2021 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Neonatal Life Support; Education, Implementation, and Teams; First Aid Task Forces; and the COVID-19 Working Group. Resuscitation, 169229-311. https://doi.org/10.1016/j.resuscitation.2021.10.040
Wyckoff, Myra H, et al. "2021 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Neonatal Life Support; Education, Implementation, and Teams; First Aid Task Forces; and the COVID-19 Working Group." Resuscitation vol. 169 (2021): 229-311. doi: https://doi.org/10.1016/j.resuscitation.2021.10.040
Wyckoff MH, Singletary EM, Soar J, Olasveengen TM, Greif R, Liley HG, Zideman D, Bhanji F, Andersen LW, Avis SR, Aziz K, Bendall JC, Berry DC, Borra V, Böttiger BW, Bradley R, Bray JE, Breckwoldt J, Carlson JN, Cassan P, Castrén M, Chang WT, Charlton NP, Cheng A, Chung SP, Considine J, Costa-Nobre DT, Couper K, Dainty KN, Davis PG, de Almeida MF, de Caen AR, de Paiva EF, Deakin CD, Djärv T, Douma MJ, Drennan IR, Duff JP, Eastwood KJ, El-Naggar W, Epstein JL, Escalante R, Fabres JG, Fawke J, Finn JC, Foglia EE, Folke F, Freeman K, Gilfoyle E, Goolsby CA, Grove A, Guinsburg R, Hatanaka T, Hazinski MF, Heriot GS, Hirsch KG, Holmberg MJ, Hosono S, Hsieh MJ, Hung KKC, Hsu CH, Ikeyama T, Isayama T, Kapadia VS, Kawakami MD, Kim HS, Kloeck DA, Kudenchuk PJ, Lagina AT, Lauridsen KG, Lavonas EJ, Lockey AS, Malta Hansen C, Markenson D, Matsuyama T, McKinlay CJD, Mehrabian A, Merchant RM, Meyran D, Morley PT, Morrison LJ, Nation KJ, Nemeth M, Neumar RW, Nicholson T, Niermeyer S, Nikolaou N, Nishiyama C, O'Neil BJ, Orkin AM, Osemeke O, Parr MJ, Patocka C, Pellegrino JL, Perkins GD, Perlman JM, Rabi Y, Reynolds JC, Ristagno G, Roehr CC, Sakamoto T, Sandroni C, Sawyer T, Schmölzer GM, Schnaubelt S, Semeraro F, Skrifvars MB, Smith CM, Smyth MA, Soll RF, Sugiura T, Taylor-Phillips S, Trevisanuto D, Vaillancourt C, Wang TL, Weiner GM, Welsford M, Wigginton J, Wyllie JP, Yeung J, Nolan JP, Berg KM. 2021 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Neonatal Life Support; Education, Implementation, and Teams; First Aid Task Forces; and the COVID-19 Working Group. Resuscitation. 2021 Dec;169:229-311. doi: 10.1016/j.resuscitation.2021.10.040. Epub 2021 Nov 11. PMID: 34933747.
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[Education].

Notfall & rettungsmedizin

Lott C, Carmona F, Van de Voorde P, Lockey A, Kuzovlev A, Breckwoldt J, Nolan JP, Monsieurs KG, Madar J, Turner N, Scapigliati A, Pflanzl-Knizacek L, Conaghan P, Biarent D, Greif R.
PMID: 32536803
Notf Rett Med. 2020;23(4):260-262. doi: 10.1007/s10049-020-00723-6. Epub 2020 Jun 10.

No abstract available.

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Lott C, Carmona F, Van de Voorde P, et al. Ausbildung: COVID-19-Leitlinien des European Resuscitation Council. [Education]. Notf Rett Med. 2020;23(4):260-262doi: 10.1007/s10049-020-00723-6.
Lott, C., Carmona, F., Van de Voorde, P., Lockey, A., Kuzovlev, A., Breckwoldt, J., Nolan, J. P., Monsieurs, K. G., Madar, J., Turner, N., Scapigliati, A., Pflanzl-Knizacek, L., Conaghan, P., Biarent, D., & Greif, R. (2020). Ausbildung: COVID-19-Leitlinien des European Resuscitation Council. [Education]. Notfall & rettungsmedizin, 23(4), 260-262. https://doi.org/10.1007/s10049-020-00723-6
Lott, C, et al. "Ausbildung: COVID-19-Leitlinien des European Resuscitation Council." [Education]. Notfall & rettungsmedizin vol. 23,4 (2020): 260-262. doi: https://doi.org/10.1007/s10049-020-00723-6
Lott C, Carmona F, Van de Voorde P, Lockey A, Kuzovlev A, Breckwoldt J, Nolan JP, Monsieurs KG, Madar J, Turner N, Scapigliati A, Pflanzl-Knizacek L, Conaghan P, Biarent D, Greif R. Ausbildung: COVID-19-Leitlinien des European Resuscitation Council. [Education]. Notf Rett Med. 2020;23(4):260-262. doi: 10.1007/s10049-020-00723-6. Epub 2020 Jun 10. German. PMID: 32536803; PMCID: PMC7284663.
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Diagnostic value of gadolinium contrast administration for spinal cord magnetic resonance imaging in multiple sclerosis patients and correlative markers of lesion enhancement.

Multiple sclerosis journal - experimental, translational and clinical

Karimian-Jazi K, Neuberger U, Schregel K, Brugnara G, Bendszus M, Breckwoldt MO, Schwarz D, Jäger LB, Wick W.
PMID: 34868625
Mult Scler J Exp Transl Clin. 2021 Nov 26;7(4):20552173211047978. doi: 10.1177/20552173211047978. eCollection 2021 Oct.

BACKGROUND: Magnetic resonance imaging is essential for monitoring people with multiple sclerosis, but the diagnostic value of gadolinium contrast administration in spine magnetic resonance imaging is unclear.OBJECTIVE: To assess the diagnostic value of gadolinium contrast administration in spine magnetic...

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Karimian-Jazi K, Neuberger U, Schregel K, et al. Diagnostic value of gadolinium contrast administration for spinal cord magnetic resonance imaging in multiple sclerosis patients and correlative markers of lesion enhancement. Mult Scler J Exp Transl Clin. 2021;7(4):20552173211047978doi: 10.1177/20552173211047978.
Karimian-Jazi, K., Neuberger, U., Schregel, K., Brugnara, G., Bendszus, M., Breckwoldt, M. O., Schwarz, D., Jäger, L. B., & Wick, W. (2021). Diagnostic value of gadolinium contrast administration for spinal cord magnetic resonance imaging in multiple sclerosis patients and correlative markers of lesion enhancement. Multiple sclerosis journal - experimental, translational and clinical, 7(4), 20552173211047978. https://doi.org/10.1177/20552173211047978
Karimian-Jazi, Kianush, et al. "Diagnostic value of gadolinium contrast administration for spinal cord magnetic resonance imaging in multiple sclerosis patients and correlative markers of lesion enhancement." Multiple sclerosis journal - experimental, translational and clinical vol. 7,4 (2021): 20552173211047978. doi: https://doi.org/10.1177/20552173211047978
Karimian-Jazi K, Neuberger U, Schregel K, Brugnara G, Bendszus M, Breckwoldt MO, Schwarz D, Jäger LB, Wick W. Diagnostic value of gadolinium contrast administration for spinal cord magnetic resonance imaging in multiple sclerosis patients and correlative markers of lesion enhancement. Mult Scler J Exp Transl Clin. 2021 Nov 26;7(4):20552173211047978. doi: 10.1177/20552173211047978. eCollection 2021 Oct. PMID: 34868625; PMCID: PMC8637714.
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Clinical Value of Susceptibility Weighted Imaging of Brain Metastases.

Frontiers in neurology

Schwarz D, Bendszus M, Breckwoldt MO.
PMID: 32117017
Front Neurol. 2020 Feb 04;11:55. doi: 10.3389/fneur.2020.00055. eCollection 2020.

MRI is used for screening, initial diagnosis and follow-up of brain metastases. Multiparametric MRI protocols encompass an array of image sequences to depict key aspects of metastases morphology and biology. Given the recent safety concerns of Gd-administration and the...

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Schwarz D, Bendszus M, Breckwoldt MO. Clinical Value of Susceptibility Weighted Imaging of Brain Metastases. Front Neurol. 2020;11:55doi: 10.3389/fneur.2020.00055.
Schwarz, D., Bendszus, M., & Breckwoldt, M. O. (2020). Clinical Value of Susceptibility Weighted Imaging of Brain Metastases. Frontiers in neurology, 1155. https://doi.org/10.3389/fneur.2020.00055
Schwarz, Daniel, et al. "Clinical Value of Susceptibility Weighted Imaging of Brain Metastases." Frontiers in neurology vol. 11 (2020): 55. doi: https://doi.org/10.3389/fneur.2020.00055
Schwarz D, Bendszus M, Breckwoldt MO. Clinical Value of Susceptibility Weighted Imaging of Brain Metastases. Front Neurol. 2020 Feb 04;11:55. doi: 10.3389/fneur.2020.00055. eCollection 2020. PMID: 32117017; PMCID: PMC7010951.
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Comparing Classroom Instruction to Individual Instruction as an Approach to Teach Avatar-Based Patient Monitoring With Visual Patient: Simulation Study.

JMIR medical education

Rössler J, Kaserer A, Albiez B, Braun J, Breckwoldt J, Spahn DR, Nöthiger C, Tscholl DW.
PMID: 32205304
JMIR Med Educ. 2020 Apr 23;6(1):e17922. doi: 10.2196/17922.

BACKGROUND: Visual Patient is an avatar-based alternative to standard patient monitor displays that significantly improves the perception of vital signs. Implementation of this technology in larger organizations would require it to be teachable by brief class instruction to large...

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Rössler J, Kaserer A, Albiez B, et al. Comparing Classroom Instruction to Individual Instruction as an Approach to Teach Avatar-Based Patient Monitoring With Visual Patient: Simulation Study. JMIR Med Educ. 2020;6(1):e17922doi: 10.2196/17922.
Rössler, J., Kaserer, A., Albiez, B., Braun, J., Breckwoldt, J., Spahn, D. R., Nöthiger, C., & Tscholl, D. W. (2020). Comparing Classroom Instruction to Individual Instruction as an Approach to Teach Avatar-Based Patient Monitoring With Visual Patient: Simulation Study. JMIR medical education, 6(1), e17922. https://doi.org/10.2196/17922
Rössler, Julian, et al. "Comparing Classroom Instruction to Individual Instruction as an Approach to Teach Avatar-Based Patient Monitoring With Visual Patient: Simulation Study." JMIR medical education vol. 6,1 (2020): e17922. doi: https://doi.org/10.2196/17922
Rössler J, Kaserer A, Albiez B, Braun J, Breckwoldt J, Spahn DR, Nöthiger C, Tscholl DW. Comparing Classroom Instruction to Individual Instruction as an Approach to Teach Avatar-Based Patient Monitoring With Visual Patient: Simulation Study. JMIR Med Educ. 2020 Apr 23;6(1):e17922. doi: 10.2196/17922. PMID: 32205304; PMCID: PMC7206517.
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Correction: Comparing Classroom Instruction to Individual Instruction as an Approach to Teach Avatar-Based Patient Monitoring With Visual Patient: Simulation Study.

JMIR medical education

Rössler J, Kaserer A, Albiez B, Braun J, Breckwoldt J, Spahn DR, Nöthiger C, Tscholl DW.
PMID: 33001840
JMIR Med Educ. 2020 Oct 01;6(2):e24459. doi: 10.2196/24459.

[This corrects the article DOI: 10.2196/17922.].

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Rössler J, Kaserer A, Albiez B, et al. Correction: Comparing Classroom Instruction to Individual Instruction as an Approach to Teach Avatar-Based Patient Monitoring With Visual Patient: Simulation Study. JMIR Med Educ. 2020;6(2):e24459doi: 10.2196/24459.
Rössler, J., Kaserer, A., Albiez, B., Braun, J., Breckwoldt, J., Spahn, D. R., Nöthiger, C., & Tscholl, D. W. (2020). Correction: Comparing Classroom Instruction to Individual Instruction as an Approach to Teach Avatar-Based Patient Monitoring With Visual Patient: Simulation Study. JMIR medical education, 6(2), e24459. https://doi.org/10.2196/24459
Rössler, Julian, et al. "Correction: Comparing Classroom Instruction to Individual Instruction as an Approach to Teach Avatar-Based Patient Monitoring With Visual Patient: Simulation Study." JMIR medical education vol. 6,2 (2020): e24459. doi: https://doi.org/10.2196/24459
Rössler J, Kaserer A, Albiez B, Braun J, Breckwoldt J, Spahn DR, Nöthiger C, Tscholl DW. Correction: Comparing Classroom Instruction to Individual Instruction as an Approach to Teach Avatar-Based Patient Monitoring With Visual Patient: Simulation Study. JMIR Med Educ. 2020 Oct 01;6(2):e24459. doi: 10.2196/24459. PMID: 33001840; PMCID: PMC7563624.
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Identification and Characterization of Cancer Cells That Initiate Metastases to the Brain and Other Organs.

Molecular cancer research : MCR

Berghoff AS, Liao Y, Karreman MA, Ilhan-Mutlu A, Gunkel K, Sprick MR, Eisen C, Kessler T, Osswald M, Wünsche S, Feinauer M, Gril B, Marmé F, Michel LL, Bago-Horvath Z, Sahm F, Becker N, Breckwoldt MO, Solecki G, Gömmel M, Huang L, Rübmann P, Thome CM, Ratliff M, Trumpp A, Steeg PS, Preusser M, Wick W, Winkler F.
PMID: 33443114
Mol Cancer Res. 2021 Apr;19(4):688-701. doi: 10.1158/1541-7786.MCR-20-0863. Epub 2020 Dec 22.

Specific biological properties of those circulating cancer cells that are the origin of brain metastases (BM) are not well understood. Here, single circulating breast cancer cells were fate-tracked during all steps of the brain metastatic cascade in mice after...

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Berghoff AS, Liao Y, Karreman MA, et al. Identification and Characterization of Cancer Cells That Initiate Metastases to the Brain and Other Organs. Mol Cancer Res. 2020;19(4):688-701doi: 10.1158/1541-7786.MCR-20-0863.
Berghoff, A. S., Liao, Y., Karreman, M. A., Ilhan-Mutlu, A., Gunkel, K., Sprick, M. R., Eisen, C., Kessler, T., Osswald, M., Wünsche, S., Feinauer, M., Gril, B., Marmé, F., Michel, L. L., Bago-Horvath, Z., Sahm, F., Becker, N., Breckwoldt, M. O., Solecki, G., Gömmel, M., Huang, L., Rübmann, P., Thome, C. M., Ratliff, M., Trumpp, A., Steeg, P. S., Preusser, M., Wick, W., & Winkler, F. (2021). Identification and Characterization of Cancer Cells That Initiate Metastases to the Brain and Other Organs. Molecular cancer research : MCR, 19(4), 688-701. https://doi.org/10.1158/1541-7786.MCR-20-0863
Berghoff, Anna S, et al. "Identification and Characterization of Cancer Cells That Initiate Metastases to the Brain and Other Organs." Molecular cancer research : MCR vol. 19,4 (2021): 688-701. doi: https://doi.org/10.1158/1541-7786.MCR-20-0863
Berghoff AS, Liao Y, Karreman MA, Ilhan-Mutlu A, Gunkel K, Sprick MR, Eisen C, Kessler T, Osswald M, Wünsche S, Feinauer M, Gril B, Marmé F, Michel LL, Bago-Horvath Z, Sahm F, Becker N, Breckwoldt MO, Solecki G, Gömmel M, Huang L, Rübmann P, Thome CM, Ratliff M, Trumpp A, Steeg PS, Preusser M, Wick W, Winkler F. Identification and Characterization of Cancer Cells That Initiate Metastases to the Brain and Other Organs. Mol Cancer Res. 2021 Apr;19(4):688-701. doi: 10.1158/1541-7786.MCR-20-0863. Epub 2020 Dec 22. PMID: 33443114.
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T-cell Receptor Therapy Targeting Mutant Capicua Transcriptional Repressor in Experimental Gliomas.

Clinical cancer research : an official journal of the American Association for Cancer Research

Kilian M, Friedrich M, Sanghvi K, Green E, Pusch S, Kawauchi D, Löwer M, Sonner JK, Krämer C, Zaman J, Jung S, Breckwoldt MO, Willimksy G, Eichmüller SB, von Deimling A, Wick W, Sahm F, Platten M, Bunse L.
PMID: 34782365
Clin Cancer Res. 2021 Nov 15; doi: 10.1158/1078-0432.CCR-21-1881. Epub 2021 Nov 15.

PURPOSE: Gliomas are intrinsic brain tumors with a high degree of constitutive and acquired resistance to standard therapeutic modalities such as radiotherapy and alkylating chemotherapy. Glioma subtypes are recognized by characteristic mutations. Some of these characteristic mutations have shown...

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Kilian M, Friedrich M, Sanghvi K, et al. T-cell Receptor Therapy Targeting Mutant Capicua Transcriptional Repressor in Experimental Gliomas. Clin Cancer Res. 2021;doi: 10.1158/1078-0432.CCR-21-1881.
Kilian, M., Friedrich, M., Sanghvi, K., Green, E., Pusch, S., Kawauchi, D., Löwer, M., Sonner, J. K., Krämer, C., Zaman, J., Jung, S., Breckwoldt, M. O., Willimksy, G., Eichmüller, S. B., von Deimling, A., Wick, W., Sahm, F., Platten, M., & Bunse, L. (2021). T-cell Receptor Therapy Targeting Mutant Capicua Transcriptional Repressor in Experimental Gliomas. Clinical cancer research : an official journal of the American Association for Cancer Research, . https://doi.org/10.1158/1078-0432.CCR-21-1881
Kilian, Michael, et al. "T-cell Receptor Therapy Targeting Mutant Capicua Transcriptional Repressor in Experimental Gliomas." Clinical cancer research : an official journal of the American Association for Cancer Research vol. (2021). doi: https://doi.org/10.1158/1078-0432.CCR-21-1881
Kilian M, Friedrich M, Sanghvi K, Green E, Pusch S, Kawauchi D, Löwer M, Sonner JK, Krämer C, Zaman J, Jung S, Breckwoldt MO, Willimksy G, Eichmüller SB, von Deimling A, Wick W, Sahm F, Platten M, Bunse L. T-cell Receptor Therapy Targeting Mutant Capicua Transcriptional Repressor in Experimental Gliomas. Clin Cancer Res. 2021 Nov 15; doi: 10.1158/1078-0432.CCR-21-1881. Epub 2021 Nov 15. PMID: 34782365.
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Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model.

Neuro-oncology

Simovic M, Bolkestein M, Moustafa M, Wong JKL, Körber V, Benedetto S, Khalid U, Schreiber HS, Jugold M, Korshunov A, Hübschmann D, Mack N, Brons S, Wei PC, Breckwoldt MO, Heiland S, Bendszus M, Debus J, Höfer T, Zapatka M, Kool M, Pfister SM, Abdollahi A, Ernst A.
PMID: 34049392
Neuro Oncol. 2021 Dec 01;23(12):2028-2041. doi: 10.1093/neuonc/noab127.

BACKGROUND: Medulloblastomas with chromothripsis developing in children with Li-Fraumeni Syndrome (germline TP53 mutations) are highly aggressive brain tumors with dismal prognosis. Conventional photon radiotherapy and DNA-damaging chemotherapy are not successful for these patients and raise the risk of secondary...

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Simovic M, Bolkestein M, Moustafa M, et al. Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model. Neuro Oncol. 2021;23(12):2028-2041doi: 10.1093/neuonc/noab127.
Simovic, M., Bolkestein, M., Moustafa, M., Wong, J. K. L., Körber, V., Benedetto, S., Khalid, U., Schreiber, H. S., Jugold, M., Korshunov, A., Hübschmann, D., Mack, N., Brons, S., Wei, P. C., Breckwoldt, M. O., Heiland, S., Bendszus, M., Debus, J., Höfer, T., Zapatka, M., Kool, M., Pfister, S. M., Abdollahi, A., & Ernst, A. (2021). Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model. Neuro-oncology, 23(12), 2028-2041. https://doi.org/10.1093/neuonc/noab127
Simovic, Milena, et al. "Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model." Neuro-oncology vol. 23,12 (2021): 2028-2041. doi: https://doi.org/10.1093/neuonc/noab127
Simovic M, Bolkestein M, Moustafa M, Wong JKL, Körber V, Benedetto S, Khalid U, Schreiber HS, Jugold M, Korshunov A, Hübschmann D, Mack N, Brons S, Wei PC, Breckwoldt MO, Heiland S, Bendszus M, Debus J, Höfer T, Zapatka M, Kool M, Pfister SM, Abdollahi A, Ernst A. Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model. Neuro Oncol. 2021 Dec 01;23(12):2028-2041. doi: 10.1093/neuonc/noab127. PMID: 34049392; PMCID: PMC8643436.
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