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Showing 1 to 12 of 139 entries
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Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide.

Angewandte Chemie (International ed. in English)

Bisson C, Britton KL, Sedelnikova SE, Rodgers HF, Eadsforth TC, Viner RC, Hawkes TR, Baker PJ, Rice DW.
PMID: 27717128
Angew Chem Int Ed Engl. 2016 Oct 17;55(43):13485-13489. doi: 10.1002/anie.201607185. Epub 2016 Sep 26.

Programs of drug discovery generally exploit one enantiomer of a chiral compound for lead development following the principle that enantiomer recognition is central to biological specificity. However, chiral promiscuity has been identified for a number of enzyme families, which...

Divergent role of nitric oxide in insulin-stimulated aortic vasorelaxation between low- and high-intrinsic aerobic capacity rats.

Physiological reports

Crissey JM, Padilla J, Vieira-Potter VJ, Thorne PK, Koch LG, Britton SL, Thyfault JP, Laughlin MH.
PMID: 26197933
Physiol Rep. 2015 Jul;3(7). doi: 10.14814/phy2.12459.

Low-intrinsic aerobic capacity is associated with increased risk for cardiovascular and metabolic diseases and is a strong predictor of early mortality. The effects of intrinsic aerobic capacity on the vascular response to insulin are largely unknown. We tested the...

Development of an implantable oximetry-based organ perfusion sensor.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference

Ericson MN, Wilson M, Cote G, Britton CL, Xu W, Baba J, Bobrek M, Hileman M, Moore M, Frank S.
PMID: 17272171
Conf Proc IEEE Eng Med Biol Soc. 2004;2004:2235-8. doi: 10.1109/IEMBS.2004.1403651.

A sensor system enabling real-time monitoring of organ perfusion following transplantation is presented. This system uses a three wavelength oximetry-based approach. The instrument is intended for implantation at the organ site during transplantation to provide real-time reporting of the...

RESEARCH FUNDS OF THE SCIENTIFIC ALLIANCE OF NEW YORK.

Science (New York, N.Y.)

Brinton NL.
PMID: 17789353
Science. 1903 Feb 20;17(425):314-5. doi: 10.1126/science.17.425.314.

No abstract available.

Divergent selection for aerobic capacity in rats as a model for complex disease.

Integrative and comparative biology

Koch LG, Britton SL.
PMID: 21676786
Integr Comp Biol. 2005 Jun;45(3):405-15. doi: 10.1093/icb/45.3.405.

Based upon ideas about evolution, we put forth the argument that the capacity to transfer energy via aerobic metabolism is such a central feature of mammalian biology, that it must also be the primary determinant of complex disease. From...

NOMENCLATURE AT THE VIENNA INTERNATIONAL BOTANICAL CONGRESS.

Science (New York, N.Y.)

Britton NL.
PMID: 17835754
Science. 1905 Aug 18;22(555):217-9. doi: 10.1126/science.22.555.217.

No abstract available.

Resveratrol attenuates exercise-induced adaptive responses in rats selectively bred for low running performance.

Dose-response : a publication of International Hormesis Society

Hart N, Sarga L, Csende Z, Koch LG, Britton SL, Davies KJ, Radak Z.
PMID: 24659933
Dose Response. 2013 Jun 04;12(1):57-71. doi: 10.2203/dose-response.13-010.Radak. eCollection 2014 Jan.

Low capacity runner (LCR) rats have been developed by divergent artificial selection for treadmill endurance capacity to explore an aerobic biology-disease connection. The beneficial effects of resveratrol supplementation have been demonstrated in endurance running. In this study it was...

Ferroportin Expression in Adipocytes Does Not Contribute to Iron Homeostasis or Metabolic Responses to a High Calorie Diet.

Cellular and molecular gastroenterology and hepatology

Britton L, Jaskowski LA, Bridle K, Secondes E, Wallace D, Santrampurwala N, Reiling J, Miller G, Mangiafico S, Andrikopoulos S, Subramaniam VN, Crawford D.
PMID: 29552621
Cell Mol Gastroenterol Hepatol. 2018 Jan 09;5(3):319-331. doi: 10.1016/j.jcmgh.2018.01.005. eCollection 2018 Mar.

BACKGROUND & AIMS: Iron has an increasingly recognized role in the regulation of adipose tissue function, including the expression of adipokines involved in the pathogenesis of nonalcoholic fatty liver disease. The cellular iron exporter, ferroportin, has been proposed as...

Dental Plaque Ultrastructure As Revealed by Freeze-Etching.

Journal of periodontology

Newman HN, Britton AB.
PMID: 29538834
J Periodontol. 1974 Jul;45(7):478-488. doi: 10.1902/jop.1974.45.7.478.

No abstract available.

Reducing Blood Testing in Pediatric Patients after Heart Surgery: Proving Sustainability.

Pediatric quality & safety

Bodily SA, Delgado-Corcoran C, Wolpert K, Lucas K, Presson AP, Bratton SL.
PMID: 30229183
Pediatr Qual Saf. 2017 Dec 07;2(6):e047. doi: 10.1097/pq9.0000000000000047. eCollection 2017.

INTRODUCTION: Frequent blood testing increases risk of iatrogenic anemia, infection, and blood transfusion. This study describes 3 years of sustained blood testing reduction from a quality improvement (QI) initiative which began in 2011.METHODS: The cohort consisted of postop children...

Ecology and Infection Dynamics of Multi-Host Amdoparvoviral and Protoparvoviral Carnivore Pathogens.

Pathogens (Basel, Switzerland)

Canuti M, Todd M, Monteiro P, Van Osch K, Weir R, Schwantje H, Britton AP, Lang AS.
PMID: 32075256
Pathogens. 2020 Feb 15;9(2). doi: 10.3390/pathogens9020124.

No abstract available.

Soft-x-ray-induced spin-state switching of an adsorbed Fe(II) spin-crossover complex.

Journal of physics. Condensed matter : an Institute of Physics journal

Kipgen L, Bernien M, Nickel F, Naggert H, Britton AJ, Arruda LM, Schierle E, Weschke E, Tuczek F, Kuch W.
PMID: 28685708
J Phys Condens Matter. 2017 Oct 04;29(39):394003. doi: 10.1088/1361-648X/aa7e52. Epub 2017 Jul 07.

For probing the nature of spin-state switching in spin-crossover molecules adsorbed on surfaces, x-ray absorption spectroscopy has emerged as a powerful tool due to its high sensitivity and element selectivity in tracing even subtle electronic, magnetic, or chemical changes....

Showing 1 to 12 of 139 entries