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Showing 1 to 12 of 266 entries
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Solvatochromic rotaxane molecular shuttles.

Chemical communications (Cambridge, England)

Günbaş DD, Zalewski L, Brouwer AM.
PMID: 21431115
Chem Commun (Camb). 2011 May 07;47(17):4977-9. doi: 10.1039/c0cc05755j. Epub 2011 Mar 22.

A strongly fluorescent bistable rotaxane is described in which the relative position of the macrocyclic ring with respect to a solvatochromic fluorophore gives a strong response in the spectral domain.

Mechanistic Modeling Reveals the Critical Knowledge Gaps in Bile Acid-Mediated DILI.

CPT: pharmacometrics & systems pharmacology

Woodhead JL, Yang K, Brouwer KL, Siler SQ, Stahl SH, Ambroso JL, Baker D, Watkins PB, Howell BA.
PMID: 25006780
CPT Pharmacometrics Syst Pharmacol. 2014 Jul 09;3:e123. doi: 10.1038/psp.2014.21.

Bile salt export pump (BSEP) inhibition has been proposed to be an important mechanism for drug-induced liver injury (DILI). Modeling can prioritize knowledge gaps concerning bile acid (BA) homeostasis and thus help guide experimentation. A submodel of BA homeostasis...

Mechanical Stress Changes the Complex Interplay Between HO-1, Inflammation and Fibrosis, During Excisional Wound Repair.

Frontiers in medicine

Cremers NA, Suttorp M, Gerritsen MM, Wong RJ, van Run-van Breda C, van Dam GM, Brouwer KM, Kuijpers-Jagtman AM, Carels CE, Lundvig DM, Wagener FA.
PMID: 26697429
Front Med (Lausanne). 2015 Dec 15;2:86. doi: 10.3389/fmed.2015.00086. eCollection 2015.

Mechanical stress following surgery or injury can promote pathological wound healing and fibrosis, and lead to functional loss and esthetic problems. Splinted excisional wounds can be used as a model for inducing mechanical stress. The cytoprotective enzyme heme oxygenase-1...

Photoinduction of fast, reversible translational motion in a hydrogen-bonded molecular shuttle.

Science (New York, N.Y.)

Brouwer AM, Frochot C, Gatti FG, Leigh DA, Mottier L, Paolucci F, Roffia S, Wurpel GW.
PMID: 11251112
Science. 2001 Mar 16;291(5511):2124-8. doi: 10.1126/science.1057886. Epub 2001 Feb 22.

A rotaxane is described in which a macrocycle moves reversibly between two hydrogen-bonding stations after a nanosecond laser pulse. Observation of transient changes in the optical absorption spectrum after photoexcitation allows direct quantitative monitoring of the submolecular translational process....

Combined solid state NMR and X-ray diffraction investigation of the local structure of the five-coordinate silicon in fluoride-containing as-synthesized STF zeolite.

Journal of the American Chemical Society

Fyfe CA, Brouwer DH, Lewis AR, Villaescusa LA, Morris RE.
PMID: 12083931
J Am Chem Soc. 2002 Jul 03;124(26):7770-8. doi: 10.1021/ja012558s.

The local structure of the [SiO(4/2)F]- unit in fluoride-containing as-synthesized STF zeolite has been experimentally determined by a combination of solid-state NMR and microcrystal X-ray diffraction to be very close to trigonal bipyramidal. Because the fluoride ions are disordered...

Infrared study of intercomponent interactions in a switchable hydrogen-bonded rotaxane.

Chemistry (Weinheim an der Bergstrasse, Germany)

Jagesar DC, Hartl F, Buma WJ, Brouwer AM.
PMID: 18064626
Chemistry. 2008;14(6):1935-46. doi: 10.1002/chem.200701531.

The macrocycle in rotaxane 1 is preferentially hydrogen bonded to the succinamide station in the neutral form, but can be moved to the naphthalimide station by one-electron reduction of the latter. The hydrogen bonding between the amide NH groups...

(35)Cl solid-state NMR of halide ionic liquids at ultrahigh fields.

The journal of physical chemistry. A

Gordon PG, Brouwer DH, Ripmeester JA.
PMID: 19007195
J Phys Chem A. 2008 Dec 11;112(49):12527-9. doi: 10.1021/jp808524h.

This Letter describes recent work investigating the solid-state NMR spectra of (35)Cl nuclei in an assortment of ionic liquids under static and MAS conditions at field strengths of 9.4 and 21.1 T. At high field it was possible to...

Benefits transfer of willingness to pay estimates and functions for health-risk reductions: a cross-country study.

Journal of health economics

Brouwer R, Bateman IJ.
PMID: 15811545
J Health Econ. 2005 May;24(3):591-611. doi: 10.1016/j.jhealeco.2004.09.004. Epub 2004 Dec 10.

This paper provides a first application of the techniques of benefits transfer to the health economics literature. These techniques seek to transfer the value of some good from one 'survey' context to a new 'policy' context so avoiding the...

Symmetry-based 29Si dipolar recoupling magic angle spinning NMR spectroscopy: a new method for investigating three-dimensional structures of zeolite frameworks.

Journal of the American Chemical Society

Brouwer DH, Kristiansen PE, Fyfe CA, Levitt MH.
PMID: 15643876
J Am Chem Soc. 2005 Jan 19;127(2):542-3. doi: 10.1021/ja043228l.

A new 29Si solid-state MAS NMR experiment is described for investigating the framework structures of pure silica zeolites. The symmetry-based homonuclear dipolar recoupling sequence SR26411 has been incorporated into a two-dimensional NMR experiment to probe the Si-O-Si bonding connectivities...

Efficacy of integrated school based de-worming and prompt malaria treatment on helminths -Plasmodium falciparum co-infections: A 33 months follow up study.

BMC international health and human rights

Midzi N, Mtapuri-Zinyowera S, Sangweme D, Paul NH, Makware G, Mapingure MP, Brouwer KC, Mudzori J, Hlerema G, Chadukura V, Mutapi F, Kumar N, Mduluza T.
PMID: 21696629
BMC Int Health Hum Rights. 2011 Jun 22;11:9. doi: 10.1186/1472-698X-11-9.

BACKGROUND: The geographical congruency in distribution of helminths and Plasmodium falciparum makes polyparasitism a common phenomenon in Sub Saharan Africa. The devastating effects of helminths-Plasmodium co-infections on primary school health have raised global interest for integrated control. However little...

On the synergistic catalytic properties of bimetallic mesoporous materials containing aluminum and zirconium: the Prins cyclisation of citronellal.

Chemistry (Weinheim an der Bergstrasse, Germany)

Telalović S, Ramanathan A, Ng JF, Maheswari R, Kwakernaak C, Soulimani F, Brouwer HC, Chuah GK, Weckhuysen BM, Hanefeld U.
PMID: 21259348
Chemistry. 2011 Feb 11;17(7):2077-88. doi: 10.1002/chem.201002909. Epub 2011 Jan 21.

Bimetallic three-dimensional amorphous mesoporous materials, Al-Zr-TUD-1 materials, were synthesised by using a surfactant-free, one-pot procedure employing triethanolamine (TEA) as a complexing reagent. The amount of aluminium and zirconium was varied in order to study the effect of these metals...

Perceiving blocks of emotional pictures and sounds: effects on physiological variables.

Frontiers in human neuroscience

Brouwer AM, van Wouwe N, Mühl C, van Erp J, Toet A.
PMID: 23801957
Front Hum Neurosci. 2013 Jun 21;7:295. doi: 10.3389/fnhum.2013.00295. eCollection 2013.

Most studies on physiological effects of emotion-inducing images and sounds examine stimulus locked variables reflecting a state of at most a few seconds. We here aimed to induce longer lasting emotional states using blocks of repetitive visual, auditory, and...

Showing 1 to 12 of 266 entries