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Showing 1 to 12 of 476 entries
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Cardiovascular disease and type 2 diabetes in evolutionary perspective: a critical role for helminths?.

Evolution, medicine, and public health

Gurven MD, Trumble BC, Stieglitz J, Blackwell AD, Michalik DE, Finch CE, Kaplan HS.
PMID: 27666719
Evol Med Public Health. 2016 Jan;2016(1):338-357. doi: 10.1093/emph/eow028. Epub 2016 Sep 25.

Heart disease and type 2 diabetes are commonly believed to be rare among contemporary subsistence-level human populations, and by extension prehistoric populations. Although some caveats remain, evidence shows these diseases to be unusual among well-studied hunter-gatherers and other subsistence...

Automatic mechanism generation for pyrolysis of di-tert-butyl sulfide.

Physical chemistry chemical physics : PCCP

Class CA, Liu M, Vandeputte AG, Green WH.
PMID: 27431650
Phys Chem Chem Phys. 2016 Aug 03;18(31):21651-8. doi: 10.1039/c6cp02202b.

The automated Reaction Mechanism Generator (RMG), using rate parameters derived from ab initio CCSD(T) calculations, is used to build reaction networks for the thermal decomposition of di-tert-butyl sulfide. Simulation results were compared with data from pyrolysis experiments with and...

Elevated mitochondrial genome variation after 50 generations of radiation exposure in a wild rodent.

Evolutionary applications

Baker RJ, Dickins B, Wickliffe JK, Khan FAA, Gaschak S, Makova KD, Phillips CD.
PMID: 29151870
Evol Appl. 2017 Jun 22;10(8):784-791. doi: 10.1111/eva.12475. eCollection 2017 Sep.

Currently, the effects of chronic, continuous low dose environmental irradiation on the mitochondrial genome of resident small mammals are unknown. Using the bank vole (

Intermolecular insertion reactions of azides into 9-borafluorenes to generate 9,10-B,N-phenanthrenes.

Chemical communications (Cambridge, England)

Yruegas S, Martinez JJ, Martin CD.
PMID: 29547215
Chem Commun (Camb). 2018 Jun 19;54(50):6808-6811. doi: 10.1039/C8CC01529E.

The reactions of 9-borafluorenes with organic azides result in either the insertion of the α-nitrogen and elimination of N2 or the insertion of the γ-nitrogen to generate the corresponding phenanthrene analogues with boron and nitrogen in the 9- and...

Fine mapping of chromosome 15q25 implicates ZNF592 in neurosarcoidosis patients.

Annals of clinical and translational neurology

Lareau CA, Adrianto I, Levin AM, Iannuzzi MC, Rybicki BA, Montgomery CG.
PMID: 26478897
Ann Clin Transl Neurol. 2015 Oct;2(10):972-7. doi: 10.1002/acn3.229. Epub 2015 Jul 31.

Neurosarcoidosis is a clinical subtype of sarcoidosis characterized by the presence of granulomas in the nervous system. Here, we report a highly significant association with a variant (rs75652600, P = 3.12 × 10(-8), odds ratios = 4.34) within a...

Oxygen insertion into boroles as a route to 1,2-oxaborines.

Chemical communications (Cambridge, England)

Yruegas S, Patterson DC, Martin CD.
PMID: 27040724
Chem Commun (Camb). 2016 May 10;52(40):6658-61. doi: 10.1039/c6cc02040b.

The synthesis of 1,2-oxaborines is accomplished via the reaction of pentaarylboroles with N-methylmorpholine-N-oxide via a 1,1-insertion reaction. The aromatic nature of 1,2-oxaborines was evaluated by computing nuclear independent chemical shift (NICS) values. Collectively, the experimental and computational studies indicate...

Probe beam deflection optical imaging of thermal and mechanical phenomena resulting from nanosecond electric pulse (nsEP) exposure in-vitro.

Optics express

Barnes RA, Roth CC, Beier HT, Noojin G, Valdez C, Bixler J, Moen E, Shadaram M, Ibey BL.
PMID: 28381008
Opt Express. 2017 Mar 20;25(6):6621-6643. doi: 10.1364/OE.25.006621.

Electric-field induced physical phenomena, such as thermal, mechanical and electrochemical dynamics, may be the driving mechanism behind bioeffects observed in mammalian cells during exposure to nanosecond-duration electric pulses (nsEP) in-vitro. Correlating a driving mechanism to a biological response requires...

Iron catalysed Negishi cross-coupling using simple ethyl-monophosphines.

Dalton transactions (Cambridge, England : 2003)

Brown CA, Nile TA, Mahon MF, Webster RL.
PMID: 25730705
Dalton Trans. 2015 Jul 21;44(27):12189-95. doi: 10.1039/c5dt00112a. Epub 2015 Mar 02.

Monophosphines prepared by iron catalysed hydrophosphination have been used as pro-ligands in iron catalysed Negishi cross-coupling of alkyl bromides and diphenyl zinc reagents. The cross-coupling has been investigated with monophosphines with varying electronic properties and we find the simplest,...

Three-dimensional atomic-scale imaging of impurity segregation to line defects.

Science (New York, N.Y.)

Blavette D, Cadel E, Fraczkiewicz A, Menand A.
PMID: 10600736
Science. 1999 Dec 17;286(5448):2317-9. doi: 10.1126/science.286.5448.2317.

Clouds of impurity atoms near line defects are believed to affect the plastic deformation of alloys. Three-dimensional atom probe techniques were used to image these so-called Cottrell atmospheres directly. Ordered iron-aluminum alloys (40 atomic percent aluminum) doped with boron...

[Utilisation of organs proceeding from donors with heart failure: review of the pathogenesis of organic damage and the possible mechanisms of prevention].

Anales del sistema sanitario de Navarra

Ferrer JV, Herrera J, Balen E, Lera JM.
PMID: 12891458
An Sist Sanit Navar. 1997 Jan-Apr;20(1):47-55. doi: 10.23938/ASSN.0597.

There is an evident imbalance between the number of patients awaiting a kidney transplant and the availability of organs proceeding from donors with brain death. A high number of patients die each day from heart failure, whose organs could...

A new approach to internal Lewis pairs featuring a phosphenium acid and a pyridine base.

Dalton transactions (Cambridge, England : 2003)

Brazeau AL, Caputo CA, Martin CD, Jones ND, Ragogna PJ.
PMID: 20967330
Dalton Trans. 2010 Dec 07;39(45):11069-73. doi: 10.1039/c0dt01029d. Epub 2010 Oct 21.

A bis(imino)acenaphthene (BIAN) ligand containing a pendant Lewis base has been used as a new framework to support a N-heterocyclic phosphenium cation (NHP). Reactivity studies demonstrate the ability of the ligand to act as a Lewis base, while the...

Global distribution of large lunar craters: implications for resurfacing and impactor populations.

Science (New York, N.Y.)

Head JW, Fassett CI, Kadish SJ, Smith DE, Zuber MT, Neumann GA, Mazarico E.
PMID: 20847265
Science. 2010 Sep 17;329(5998):1504-7. doi: 10.1126/science.1195050.

By using high-resolution altimetric measurements of the Moon, we produced a catalog of all impact craters ≥20 kilometers in diameter on the lunar surface and analyzed their distribution and population characteristics. The most-densely cratered portion of the highlands reached...

Showing 1 to 12 of 476 entries