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Showing 1 to 12 of 161 entries
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Weekly glucagon-like peptide-1 receptor agonist albiglutide as monotherapy improves glycemic parameters in Japanese patients with type 2 diabetes mellitus: A randomized, double-blind, placebo-controlled study.

Journal of diabetes investigation

Nino A, Okuda I, Wilson TH, Yue L, Nakajima H, Tsuboi M, Carr MC, Seino Y.
PMID: 28921915
J Diabetes Investig. 2017 Sep 16; doi: 10.1111/jdi.12749. Epub 2017 Sep 16.

AIMS/INTRODUCTION: The present phase 3, randomized, double-blind 24-week study with extension to 1 year assessed the efficacy and safety of albiglutide compared with placebo in Japanese patients with type 2 diabetes mellitus inadequately controlled by diet and exercise with...

Inclusion of trans-resveratrol in methylated cyclodextrins: synthesis and solid-state structures.

Beilstein journal of organic chemistry

Trollope L, Cruickshank DL, Noonan T, Bourne SA, Sorrenti M, Catenacci L, Caira MR.
PMID: 25670983
Beilstein J Org Chem. 2014 Dec 29;10:3136-51. doi: 10.3762/bjoc.10.331. eCollection 2014.

The phytoalexin trans-resveratrol, 5-[(1E)-2-(4-hydroxyphenyl)ethenyl]-1,3-benzenediol, is a well-known, potent antioxidant having a variety of possible biomedical applications. However, its adverse physicochemical properties (low stability, poor aqueous solubility) limit such applications and its inclusion in cyclodextrins (CDs) has potential for addressing...

The NO stimulator, Catestatin, improves the Frank-Starling response in normotensive and hypertensive rat hearts.

Nitric oxide : biology and chemistry

Angelone T, Quintieri AM, Pasqua T, Filice E, Cantafio P, Scavello F, Rocca C, Mahata SK, Gattuso A, Cerra MC.
PMID: 26241941
Nitric Oxide. 2015 Nov 15;50:10-19. doi: 10.1016/j.niox.2015.07.004. Epub 2015 Aug 01.

The myocardial response to mechanical stretch (Frank-Starling law) is an important physiological cardiac determinant. Modulated by many endogenous substances, it is impaired in the presence of cardiovascular pathologies and during senescence. Catestatin (CST:hCgA352-372), a 21-amino-acid derivate of Chromogranin A...

Experience with long-term rituximab use in a multiple sclerosis clinic.

Multiple sclerosis journal - experimental, translational and clinical

Barra ME, Soni D, Vo KH, Chitnis T, Stankiewicz JM.
PMID: 28607739
Mult Scler J Exp Transl Clin. 2016 Oct 09;2:2055217316672100. doi: 10.1177/2055217316672100. eCollection 2016.

BACKGROUND: Rituximab is a monoclonal antibody directed at CD20 positive B-lymphocytes and a potential therapeutic option in the treatment of multiple sclerosis. The safety of recurrent dosing is not established.OBJECTIVES: The objective of this work was to report the...

Interaction of a phosphatidylcholine derivative of 1,6-diphenyl-1,3,5-hexatriene (DPH) with intact living cells: Steady-state fluorescence polarization and phase fluorometry studies.

Journal of fluorescence

Miccoli L, Szczepaniak C, Dumas D, Savonnière S, Muller S, Carré MC, Donner M.
PMID: 24234905
J Fluoresc. 1993 Dec;3(4):251-5. doi: 10.1007/BF00865273.

The potential interest of DPH-PC was checked with a macrophagic cell line (P388D1). The uptake of DPH-PC was associated with a rapid increase in both fluorescence intensity and a slow decrease in anisotropy values. A flow cytometry comparative study...

[Clinical Practice Guide for Early Detection, Diagnosis and Treatment of the Acute Intoxication Phase in Patients with Alcohol Abuse or Dependence: Part II: Evaluation and Management of Patients with Acute Alcohol Intoxication].

Revista colombiana de psiquiatria

de la Espriella Guerrero R, de la Hoz Bradford AM, Zárate AU, Lee PR, Menéndez MC, Rentería AM, Hernández DC, Cardeño C, Barré MC, Kunzel GH, Gómez-Restrepo C.
PMID: 26572267
Rev Colomb Psiquiatr. 2012 Dec;41(4):805-25. doi: 10.1016/S0034-7450(14)60048-2. Epub 2014 May 10.

INTRODUCTION: Worldwide, alcohol is the second most-used psychotropic substance and the third risk factor for early death and disability. Its noxious use is a world public health problem given its personal, labor, family, economic and social impact. The identification...

An Evaluation of Systemic Vancomycin Dosing in Obese Patients.

Open forum infectious diseases

Kubiak DW, Alquwaizani M, Sansonetti D, Barra ME, Calderwood MS.
PMID: 26716105
Open Forum Infect Dis. 2015 Nov 13;2(4):ofv176. doi: 10.1093/ofid/ofv176. eCollection 2015 Dec.

We retrospectively identified 67 patients with severe or morbid obesity (body mass index ≥35 kg/m(2)) who had received intravenous vancomycin at our institution. We observed that an initial dose of 45 to 65 mg/kg vancomycin per day based upon...

International orthodontics

Saulue P, Carra MC, Laluque JF, d'Incau E.
PMID: 26608468
Int Orthod. 2015 Oct 22; doi: 10.1016/j.ortho.2015.09.002. Epub 2015 Oct 22.

No abstract available.

Inclusion complexes of 2-methoxyestradiol with dimethylated and permethylated β-cyclodextrins: models for cyclodextrin-steroid interaction.

Beilstein journal of organic chemistry

Caira MR, Bourne SA, Samsodien H, Smith VJ.
PMID: 26734107
Beilstein J Org Chem. 2015 Dec 16;11:2616-30. doi: 10.3762/bjoc.11.281. eCollection 2015.

The interaction between the potent anticancer agent 2-methoxyestradiol (2ME) and a series of cyclodextrins (CDs) was investigated in the solid state using thermal analysis and X-ray diffraction, while the possibility of enhancing its poor aqueous solubility with CDs was...

Random bond XXZ chains with modulated couplings.

Physical review letters

Cabra DC, De Martino A, Grynberg MD, Peysson S, Pujol P.
PMID: 11082653
Phys Rev Lett. 2000 Nov 27;85(22):4791-4. doi: 10.1103/PhysRevLett.85.4791.

The magnetization behavior of q-periodic antiferromagnetic spin- 1/2 Heisenberg chains under uniform magnetic fields is investigated in a background of disorder exchange distributions. By means of both real space decimation procedures and numerical diagonalizations in XX chains, it is...

Tunable clathrates.

Chemical communications (Cambridge, England)

Caira MR, le Roex T, Nassimbeni LR.
PMID: 12240196
Chem Commun (Camb). 2001 Oct 21;(20):2128-9. doi: 10.1039/b106080p.

Investigation of the selectivity of a diol organic host for mixtures of DMF and DMSO, showed the formation of five inclusion compounds in which the stoichiometry varies in discrete steps and is determined by the composition of the liquid...

Diruthenium(II,III) Carboxylate Compounds: Existence of both Polymeric and Ionic Forms in Solution and Solid State.

Inorganic chemistry

Barral MC, Jiménez-Aparicio R, Priego JL, Royer EC, Urbanos FA, Amador U.
PMID: 11670354
Inorg Chem. 1998 Mar 23;37(6):1413-1416. doi: 10.1021/ic9708024.

No abstract available.

Showing 1 to 12 of 161 entries