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Personalized Medication Response Prediction for Attention-Deficit Hyperactivity Disorder: Learning in the Model Space vs. Learning in the Data Space.

Frontiers in physiology

Wong HK, Tiffin PA, Chappell MJ, Nichols TE, Welsh PR, Doyle OM, Lopez-Kolkovska BC, Inglis SK, Coghill D, Shen Y, Tiño P.
PMID: 28443027
Front Physiol. 2017 Apr 11;8:199. doi: 10.3389/fphys.2017.00199. eCollection 2017.

Attention-Deficit Hyperactive Disorder (ADHD) is one of the most common mental health disorders amongst school-aged children with an estimated prevalence of 5% in the global population (American Psychiatric Association, 2013). Stimulants, particularly methylphenidate (MPH), are the first-line option in...

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Wong HK, Tiffin PA, Chappell MJ, et al. Personalized Medication Response Prediction for Attention-Deficit Hyperactivity Disorder: Learning in the Model Space vs. Learning in the Data Space. Front Physiol. 2017;8:199doi: 10.3389/fphys.2017.00199.
Wong, H. K., Tiffin, P. A., Chappell, M. J., Nichols, T. E., Welsh, P. R., Doyle, O. M., Lopez-Kolkovska, B. C., Inglis, S. K., Coghill, D., Shen, Y., & Tiño, P. (2017). Personalized Medication Response Prediction for Attention-Deficit Hyperactivity Disorder: Learning in the Model Space vs. Learning in the Data Space. Frontiers in physiology, 8199. https://doi.org/10.3389/fphys.2017.00199
Wong, Hin K, et al. "Personalized Medication Response Prediction for Attention-Deficit Hyperactivity Disorder: Learning in the Model Space vs. Learning in the Data Space." Frontiers in physiology vol. 8 (2017): 199. doi: https://doi.org/10.3389/fphys.2017.00199
Wong HK, Tiffin PA, Chappell MJ, Nichols TE, Welsh PR, Doyle OM, Lopez-Kolkovska BC, Inglis SK, Coghill D, Shen Y, Tiño P. Personalized Medication Response Prediction for Attention-Deficit Hyperactivity Disorder: Learning in the Model Space vs. Learning in the Data Space. Front Physiol. 2017 Apr 11;8:199. doi: 10.3389/fphys.2017.00199. eCollection 2017. PMID: 28443027; PMCID: PMC5387107.
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Is tool-making knowledge robust over time and across problems?.

Frontiers in psychology

Beck SR, Cutting N, Apperly IA, Demery Z, Iliffe L, Rishi S, Chappell J.
PMID: 25538650
Front Psychol. 2014 Dec 04;5:1395. doi: 10.3389/fpsyg.2014.01395. eCollection 2014.

In three studies, we explored the retention and transfer of tool-making knowledge, learnt from an adult demonstration, to other temporal and task contexts. All studies used a variation of a task in which children had to make a hook...

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Beck SR, Cutting N, Apperly IA, et al. Is tool-making knowledge robust over time and across problems?. Front Psychol. 2014;5:1395doi: 10.3389/fpsyg.2014.01395.
Beck, S. R., Cutting, N., Apperly, I. A., Demery, Z., Iliffe, L., Rishi, S., & Chappell, J. (2014). Is tool-making knowledge robust over time and across problems?. Frontiers in psychology, 51395. https://doi.org/10.3389/fpsyg.2014.01395
Beck, Sarah R, et al. "Is tool-making knowledge robust over time and across problems?." Frontiers in psychology vol. 5 (2014): 1395. doi: https://doi.org/10.3389/fpsyg.2014.01395
Beck SR, Cutting N, Apperly IA, Demery Z, Iliffe L, Rishi S, Chappell J. Is tool-making knowledge robust over time and across problems?. Front Psychol. 2014 Dec 04;5:1395. doi: 10.3389/fpsyg.2014.01395. eCollection 2014. PMID: 25538650; PMCID: PMC4255490.
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MEMORANDUM FOR: science writers and editors on the journal press list .

Journal of the National Cancer Institute

Chappell J, Eckstein D.
PMID: 10451430
J Natl Cancer Inst. 1999 Aug 18;91(16):1347A. doi: 10.1093/jnci/91.16.1347a.

No abstract available.

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Chappell J, Eckstein D. MEMORANDUM FOR: science writers and editors on the journal press list . J Natl Cancer Inst. 1999;91(16):1347Adoi: 10.1093/jnci/91.16.1347a.
Chappell, J., & Eckstein, D. (1999). MEMORANDUM FOR: science writers and editors on the journal press list . Journal of the National Cancer Institute, 91(16), 1347A. https://doi.org/10.1093/jnci/91.16.1347a
Chappell, and Eckstein. "MEMORANDUM FOR: science writers and editors on the journal press list ." Journal of the National Cancer Institute vol. 91,16 (1999): 1347A. doi: https://doi.org/10.1093/jnci/91.16.1347a
Chappell J, Eckstein D. MEMORANDUM FOR: science writers and editors on the journal press list . J Natl Cancer Inst. 1999 Aug 18;91(16):1347A. doi: 10.1093/jnci/91.16.1347a. PMID: 10451430.
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A matched observational study of canine survival with primary intraocular melanocytic neoplasia.

Veterinary ophthalmology

Giuliano EA, Chappell R, Fischer B, Dubielzig RR.
PMID: 11397263
Vet Ophthalmol. 1999;2(3):185-190. doi: 10.1046/j.1463-5224.1999.00080.x.

A retrospective histopathologic study was performed to evaluate the effect of primary intraocular melanocytic neoplasia on canine survival. Tumor size, location within the globe, extent of infiltration, and mitotic index were analyzed for their potential to predict survival. A...

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Giuliano EA, Chappell R, Fischer B, et al. A matched observational study of canine survival with primary intraocular melanocytic neoplasia. Vet Ophthalmol. 1999;2(3):185-190doi: 10.1046/j.1463-5224.1999.00080.x.
Giuliano, E. A., Chappell, R., Fischer, B., & Dubielzig, R. R. (1999). A matched observational study of canine survival with primary intraocular melanocytic neoplasia. Veterinary ophthalmology, 2(3), 185-190. https://doi.org/10.1046/j.1463-5224.1999.00080.x
Giuliano, E.A., et al. "A matched observational study of canine survival with primary intraocular melanocytic neoplasia." Veterinary ophthalmology vol. 2,3 (1999): 185-190. doi: https://doi.org/10.1046/j.1463-5224.1999.00080.x
Giuliano EA, Chappell R, Fischer B, Dubielzig RR. A matched observational study of canine survival with primary intraocular melanocytic neoplasia. Vet Ophthalmol. 1999;2(3):185-190. doi: 10.1046/j.1463-5224.1999.00080.x. PMID: 11397263.
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The roles of the sun and the landscape in pigeon homing.

The Journal of experimental biology

Wallraff HG, Chappell J, Guilford T.
PMID: 10409483
J Exp Biol. 1999;202:2121-2126.

It seems reasonable to assume that pigeons use visual features in the landscape for orientation when they are homing over familiar terrain. Experimental evidence to prove or disprove this possibility is, however, difficult to obtain. Here, we link the...

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Wallraff HG, Chappell J, Guilford T. The roles of the sun and the landscape in pigeon homing. J Exp Biol. 1999;202:2121-2126
Wallraff, H. G., Chappell, J., & Guilford, T. (1999). The roles of the sun and the landscape in pigeon homing. The Journal of experimental biology, 2022121-2126.
Wallraff, et al. "The roles of the sun and the landscape in pigeon homing." The Journal of experimental biology vol. 202 (1999): 2121-2126.
Wallraff HG, Chappell J, Guilford T. The roles of the sun and the landscape in pigeon homing. J Exp Biol. 1999;202:2121-2126. PMID: 10409483.
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Quadrupole ion traps and trap arrays: geometry, material, scale, performance.

European journal of mass spectrometry (Chichester, England)

Ouyang Z, Gao L, Fico M, Chappell WJ, Noll RJ, Cooks RG.
PMID: 17878533
Eur J Mass Spectrom (Chichester). 2007;13(1):13-8. doi: 10.1255/ejms.832.

Quadrupole ion traps are reviewed, emphasizing recent developments, especially the investigation of new geometries, guided by multiple particle simulations such as the ITSIM program. These geometries include linear ion traps (LITs) and the simplified rectilinear ion trap (RIT). Various...

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Ouyang Z, Gao L, Fico M, et al. Quadrupole ion traps and trap arrays: geometry, material, scale, performance. Eur J Mass Spectrom (Chichester). 2007;13(1):13-8doi: 10.1255/ejms.832.
Ouyang, Z., Gao, L., Fico, M., Chappell, W. J., Noll, R. J., & Cooks, R. G. (2007). Quadrupole ion traps and trap arrays: geometry, material, scale, performance. European journal of mass spectrometry (Chichester, England), 13(1), 13-8. https://doi.org/10.1255/ejms.832
Ouyang, Z, et al. "Quadrupole ion traps and trap arrays: geometry, material, scale, performance." European journal of mass spectrometry (Chichester, England) vol. 13,1 (2007): 13-8. doi: https://doi.org/10.1255/ejms.832
Ouyang Z, Gao L, Fico M, Chappell WJ, Noll RJ, Cooks RG. Quadrupole ion traps and trap arrays: geometry, material, scale, performance. Eur J Mass Spectrom (Chichester). 2007;13(1):13-8. doi: 10.1255/ejms.832. PMID: 17878533.
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Recurrent Thrombosis of Mesenteric Veins Complicating Cirrhosis of Liver.

British medical journal

Chappell AG, Walters G.
PMID: 20789276
Br Med J. 1961 Nov 18;2(5263):1334-5. doi: 10.1136/bmj.2.5263.1334.

No abstract available.

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Chappell AG, Walters G. Recurrent Thrombosis of Mesenteric Veins Complicating Cirrhosis of Liver. Br Med J. 1961;2(5263):1334-5doi: 10.1136/bmj.2.5263.1334.
Chappell, A. G., & Walters, G. (1961). Recurrent Thrombosis of Mesenteric Veins Complicating Cirrhosis of Liver. British medical journal, 2(5263), 1334-5. https://doi.org/10.1136/bmj.2.5263.1334
Chappell, A G, and Walters, G. "Recurrent Thrombosis of Mesenteric Veins Complicating Cirrhosis of Liver." British medical journal vol. 2,5263 (1961): 1334-5. doi: https://doi.org/10.1136/bmj.2.5263.1334
Chappell AG, Walters G. Recurrent Thrombosis of Mesenteric Veins Complicating Cirrhosis of Liver. Br Med J. 1961 Nov 18;2(5263):1334-5. doi: 10.1136/bmj.2.5263.1334. PMID: 20789276; PMCID: PMC1970430.
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Reprint of "Pharmacokinetic modelling of the anti-malarial drug artesunate and its active metabolite dihydroartemisinin".

Computer methods and programs in biomedicine

Hall AJ, Chappell MJ, Aston JA, Ward SA.
PMID: 24457047
Comput Methods Programs Biomed. 2014 May;114(3):e14-28. doi: 10.1016/j.cmpb.2013.12.001. Epub 2014 Jan 20.

A four compartment mechanistic mathematical model is developed for the pharmacokinetics of the commonly used anti-malarial drug artesunate and its principle metabolite dihydroartemisinin following oral administration of artesunate. The model is structurally unidentifiable unless additional constraints are imposed. Combinations...

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Hall AJ, Chappell MJ, Aston JA, et al. Reprint of "Pharmacokinetic modelling of the anti-malarial drug artesunate and its active metabolite dihydroartemisinin". Comput Methods Programs Biomed. 2014;114(3):e14-28doi: 10.1016/j.cmpb.2013.12.001.
Hall, A. J., Chappell, M. J., Aston, J. A., & Ward, S. A. (2014). Reprint of "Pharmacokinetic modelling of the anti-malarial drug artesunate and its active metabolite dihydroartemisinin". Computer methods and programs in biomedicine, 114(3), e14-28. https://doi.org/10.1016/j.cmpb.2013.12.001
Hall, Adam J, et al. "Reprint of "Pharmacokinetic modelling of the anti-malarial drug artesunate and its active metabolite dihydroartemisinin"." Computer methods and programs in biomedicine vol. 114,3 (2014): e14-28. doi: https://doi.org/10.1016/j.cmpb.2013.12.001
Hall AJ, Chappell MJ, Aston JA, Ward SA. Reprint of "Pharmacokinetic modelling of the anti-malarial drug artesunate and its active metabolite dihydroartemisinin". Comput Methods Programs Biomed. 2014 May;114(3):e14-28. doi: 10.1016/j.cmpb.2013.12.001. Epub 2014 Jan 20. PMID: 24457047.
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Perforated Patch Recordings From Isolated Skate Bipolar Cells.

The Biological bulletin

Chappell RL, Malchow RP, Ripps H.
PMID: 29300660
Biol Bull. 1992 Oct;183(2):347-348. doi: 10.1086/BBLv183n2p347.

No abstract available.

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Chappell RL, Malchow RP, Ripps H. Perforated Patch Recordings From Isolated Skate Bipolar Cells. Biol Bull. 1992;183(2):347-348doi: 10.1086/BBLv183n2p347.
Chappell, R. L., Malchow, R. P., & Ripps, H. (1992). Perforated Patch Recordings From Isolated Skate Bipolar Cells. The Biological bulletin, 183(2), 347-348. https://doi.org/10.1086/BBLv183n2p347
Chappell, R L, et al. "Perforated Patch Recordings From Isolated Skate Bipolar Cells." The Biological bulletin vol. 183,2 (1992): 347-348. doi: https://doi.org/10.1086/BBLv183n2p347
Chappell RL, Malchow RP, Ripps H. Perforated Patch Recordings From Isolated Skate Bipolar Cells. Biol Bull. 1992 Oct;183(2):347-348. doi: 10.1086/BBLv183n2p347. PMID: 29300660.
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Comment on "Cryptosporidium Infection Risk: Results of New Dose-Response Modeling" - Discussion of Underlying Assumptions and Their Implications.

Risk analysis : an official publication of the Society for Risk Analysis

Schmidt PJ, Chappell CL.
PMID: 28085218
Risk Anal. 2016 Dec;36(12):2189-2192. doi: 10.1111/risa.12731.

No abstract available.

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Schmidt PJ, Chappell CL. Comment on "Cryptosporidium Infection Risk: Results of New Dose-Response Modeling" - Discussion of Underlying Assumptions and Their Implications. Risk Anal. 2016;36(12):2189-2192doi: 10.1111/risa.12731.
Schmidt, P. J., & Chappell, C. L. (2016). Comment on "Cryptosporidium Infection Risk: Results of New Dose-Response Modeling" - Discussion of Underlying Assumptions and Their Implications. Risk analysis : an official publication of the Society for Risk Analysis, 36(12), 2189-2192. https://doi.org/10.1111/risa.12731
Schmidt, Philip J, and Chappell, Cynthia L. "Comment on "Cryptosporidium Infection Risk: Results of New Dose-Response Modeling" - Discussion of Underlying Assumptions and Their Implications." Risk analysis : an official publication of the Society for Risk Analysis vol. 36,12 (2016): 2189-2192. doi: https://doi.org/10.1111/risa.12731
Schmidt PJ, Chappell CL. Comment on "Cryptosporidium Infection Risk: Results of New Dose-Response Modeling" - Discussion of Underlying Assumptions and Their Implications. Risk Anal. 2016 Dec;36(12):2189-2192. doi: 10.1111/risa.12731. PMID: 28085218.
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Histidine Suppresses Zinc Modulation of Connexin Hemichannels Expressed in Xenopus Oocytes.

The Biological bulletin

Chappell RL, Qian H, Zakevicius J, Ripps H.
PMID: 27690597
Biol Bull. 2004 Oct;207(2):158. doi: 10.1086/BBLv207n2p158a.

No abstract available.

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Chappell RL, Qian H, Zakevicius J, et al. Histidine Suppresses Zinc Modulation of Connexin Hemichannels Expressed in Xenopus Oocytes. Biol Bull. 2004;207(2):158doi: 10.1086/BBLv207n2p158a.
Chappell, R. L., Qian, H., Zakevicius, J., & Ripps, H. (2004). Histidine Suppresses Zinc Modulation of Connexin Hemichannels Expressed in Xenopus Oocytes. The Biological bulletin, 207(2), 158. https://doi.org/10.1086/BBLv207n2p158a
Chappell, Richard L, et al. "Histidine Suppresses Zinc Modulation of Connexin Hemichannels Expressed in Xenopus Oocytes." The Biological bulletin vol. 207,2 (2004): 158. doi: https://doi.org/10.1086/BBLv207n2p158a
Chappell RL, Qian H, Zakevicius J, Ripps H. Histidine Suppresses Zinc Modulation of Connexin Hemichannels Expressed in Xenopus Oocytes. Biol Bull. 2004 Oct;207(2):158. doi: 10.1086/BBLv207n2p158a. PMID: 27690597.
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Recent Advances in Understanding the Reversal of Gene Silencing During X Chromosome Reactivation.

Frontiers in cell and developmental biology

Talon I, Janiszewski A, Chappell J, Vanheer L, Pasque V.
PMID: 31552244
Front Cell Dev Biol. 2019 Sep 03;7:169. doi: 10.3389/fcell.2019.00169. eCollection 2019.

Dosage compensation between XX female and XY male cells is achieved by a process known as X chromosome inactivation (XCI) in mammals. XCI is initiated early during development in female cells and is subsequently stably maintained in most somatic...

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Talon I, Janiszewski A, Chappell J, et al. Recent Advances in Understanding the Reversal of Gene Silencing During X Chromosome Reactivation. Front Cell Dev Biol. 2019;7:169doi: 10.3389/fcell.2019.00169.
Talon, I., Janiszewski, A., Chappell, J., Vanheer, L., & Pasque, V. (2019). Recent Advances in Understanding the Reversal of Gene Silencing During X Chromosome Reactivation. Frontiers in cell and developmental biology, 7169. https://doi.org/10.3389/fcell.2019.00169
Talon, Irene, et al. "Recent Advances in Understanding the Reversal of Gene Silencing During X Chromosome Reactivation." Frontiers in cell and developmental biology vol. 7 (2019): 169. doi: https://doi.org/10.3389/fcell.2019.00169
Talon I, Janiszewski A, Chappell J, Vanheer L, Pasque V. Recent Advances in Understanding the Reversal of Gene Silencing During X Chromosome Reactivation. Front Cell Dev Biol. 2019 Sep 03;7:169. doi: 10.3389/fcell.2019.00169. eCollection 2019. PMID: 31552244; PMCID: PMC6733891.
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Showing 1 to 12 of 195 entries