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Gestational diabetes mellitus (GDM) decreases butyrylcholinesterase (BChE) activity and changes its relationship with lipids.

Genetics and molecular biology

Guimarães LO, de Andrade FA, Bono GF, Setoguchi TE, Brandão MB, Chautard-Freire-Maia EA, Dos Santos IC, Picheth G, Faria AC, Réa RR, Souza RL, Furtado-Alle L.
PMID: 24688284
Genet Mol Biol. 2014 Mar;37(1):1-6. doi: 10.1590/s1415-47572014000100003. Epub 2013 Feb 28.

Many conditions interfere with butyrylcholinesterase (BChE) activity, e.g., pregnancy or presence of the BCHE gene variant -116A can decrease activity whereas obesity and types I and II diabetes mellitus can increase activity. In this study, we examined BChE activity,...

Molecular forms of butyrylcholinesterase and obesity.

Genetics and molecular biology

Boberg DR, Furtado-Alle L, Souza RL, Chautard-Freire-Maia EA.
PMID: 21637414
Genet Mol Biol. 2010 Jul;33(3):452-4. doi: 10.1590/S1415-47572010005000072. Epub 2010 Sep 01.

This study compared obese (N = 134) and unobese (N = 92) male blood donors, regarding the relative intensity (RI) and activity of different molecular forms (G1, G2, G4 and G1-ALB) of butyrylcholinesterase (BChE, EC 3.1.1.8) found in plasma,...

Obesity and variants of the GHRL (ghrelin) and BCHE (butyrylcholinesterase) genes.

Genetics and molecular biology

Dantas VG, Furtado-Alle L, Souza RL, Chautard-Freire-Maia EA.
PMID: 21734817
Genet Mol Biol. 2011 Apr;34(2):205-7. doi: 10.1590/s1415-47572011000200006. Epub 2011 Apr 01.

Ghrelin coded by the GHRL gene is related to weight-gain, its deactivation possibly depending on its hydrolyzation by butyrylcholinesterase (BChE) encoded by the BCHE gene, an enzyme already associated with the body mass index (BMI). The aim was to...

Investigation of Association between Susceptibility to Leprosy and SNPs inside and near the BCHE Gene of Butyrylcholinesterase.

Journal of tropical medicine

Gomes HJ, Souza RL, Prevedello FC, Mira MT, Chautard-Freire-Maia EA.
PMID: 22523498
J Trop Med. 2012;2012:184819. doi: 10.1155/2012/184819. Epub 2012 Feb 22.

Leprosy is a chronic disease caused by Mycobacterium leprae and affects the skin and the peripheral nervous system. Butyrylcholinesterase is coded by the BCHE gene, and the atypical allele (70G; rs1799807) has been investigated as a leprosy risk factor,...

Showing 1 to 4 of 4 entries