Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 334 entries
Sorted by: Best Match Show Resources per page
Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors.

OncoTargets and therapy

Creelan BC, Gabrilovich DI, Gray JE, Williams CC, Tanvetyanon T, Haura EB, Weber JS, Gibney GT, Markowitz J, Proksch JW, Reisman SA, McKee MD, Chin MP, Meyer CJ, Antonia SJ.
PMID: 28919776
Onco Targets Ther. 2017 Aug 29;10:4239-4250. doi: 10.2147/OTT.S136992. eCollection 2017.

BACKGROUND: Omaveloxolone is a semisynthetic oleanane triterpenoid that potently activates Nrf2 with subsequent antioxidant function. We conducted a first-in-human Phase I clinical trial (NCT02029729) with the primary objectives to determine the appropriate dose for Phase II studies, characterize pharmacokinetic...

Cite
Creelan BC, Gabrilovich DI, Gray JE, et al. Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors. Onco Targets Ther. 2017;10:4239-4250doi: 10.2147/OTT.S136992.
Creelan, B. C., Gabrilovich, D. I., Gray, J. E., Williams, C. C., Tanvetyanon, T., Haura, E. B., Weber, J. S., Gibney, G. T., Markowitz, J., Proksch, J. W., Reisman, S. A., McKee, M. D., Chin, M. P., Meyer, C. J., & Antonia, S. J. (2017). Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors. OncoTargets and therapy, 104239-4250. https://doi.org/10.2147/OTT.S136992
Creelan, Ben C, et al. "Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors." OncoTargets and therapy vol. 10 (2017): 4239-4250. doi: https://doi.org/10.2147/OTT.S136992
Creelan BC, Gabrilovich DI, Gray JE, Williams CC, Tanvetyanon T, Haura EB, Weber JS, Gibney GT, Markowitz J, Proksch JW, Reisman SA, McKee MD, Chin MP, Meyer CJ, Antonia SJ. Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors. Onco Targets Ther. 2017 Aug 29;10:4239-4250. doi: 10.2147/OTT.S136992. eCollection 2017. PMID: 28919776; PMCID: PMC5587199.
Copy Download .nbib Format: NLM
Biological Phosphorus Removal During High-Rate, Low-Temperature, Anaerobic Digestion of Wastewater.

Frontiers in microbiology

Keating C, Chin JP, Hughes D, Manesiotis P, Cysneiros D, Mahony T, Smith CJ, McGrath JW, O'Flaherty V.
PMID: 26973608
Front Microbiol. 2016 Mar 03;7:226. doi: 10.3389/fmicb.2016.00226. eCollection 2016.

We report, for the first time, extensive biologically mediated phosphate removal from wastewater during high-rate anaerobic digestion (AD). A hybrid sludge bed/fixed-film (packed pumice stone) reactor was employed for low-temperature (12°C) anaerobic treatment of synthetic sewage wastewater. Successful phosphate...

Cite
Keating C, Chin JP, Hughes D, et al. Biological Phosphorus Removal During High-Rate, Low-Temperature, Anaerobic Digestion of Wastewater. Front Microbiol. 2016;7:226doi: 10.3389/fmicb.2016.00226.
Keating, C., Chin, J. P., Hughes, D., Manesiotis, P., Cysneiros, D., Mahony, T., Smith, C. J., McGrath, J. W., & O'Flaherty, V. (2016). Biological Phosphorus Removal During High-Rate, Low-Temperature, Anaerobic Digestion of Wastewater. Frontiers in microbiology, 7226. https://doi.org/10.3389/fmicb.2016.00226
Keating, Ciara, et al. "Biological Phosphorus Removal During High-Rate, Low-Temperature, Anaerobic Digestion of Wastewater." Frontiers in microbiology vol. 7 (2016): 226. doi: https://doi.org/10.3389/fmicb.2016.00226
Keating C, Chin JP, Hughes D, Manesiotis P, Cysneiros D, Mahony T, Smith CJ, McGrath JW, O'Flaherty V. Biological Phosphorus Removal During High-Rate, Low-Temperature, Anaerobic Digestion of Wastewater. Front Microbiol. 2016 Mar 03;7:226. doi: 10.3389/fmicb.2016.00226. eCollection 2016. PMID: 26973608; PMCID: PMC4776080.
Copy Download .nbib Format: NLM
Editorial Comment.

The Journal of urology

Cain MP.
PMID: 27992744
J Urol. 2017 Mar;197(3):876. doi: 10.1016/j.juro.2016.08.155. Epub 2016 Dec 16.

No abstract available.

Cite
Cain MP. Editorial Comment. J Urol. 2016;197(3):876doi: 10.1016/j.juro.2016.08.155.
Cain, M. P. (2017). Editorial Comment. The Journal of urology, 197(3), 876. https://doi.org/10.1016/j.juro.2016.08.155
Cain, Mark P. "Editorial Comment." The Journal of urology vol. 197,3 (2017): 876. doi: https://doi.org/10.1016/j.juro.2016.08.155
Cain MP. Editorial Comment. J Urol. 2017 Mar;197(3):876. doi: 10.1016/j.juro.2016.08.155. Epub 2016 Dec 16. PMID: 27992744.
Copy Download .nbib Format: NLM
Anti-malarial Activities of Two Soil Actinomycete Isolates from Sabah via Inhibition of Glycogen Synthase Kinase 3β.

Tropical life sciences research

Dahari DE, Salleh RM, Mahmud F, Chin LP, Embi N, Sidek HM.
PMID: 27688851
Trop Life Sci Res. 2016 Aug;27(2):53-71. doi: 10.21315/tlsr2016.27.2.5.

Exploiting natural resources for bioactive compounds is an attractive drug discovery strategy in search for new anti-malarial drugs with novel modes of action. Initial screening efforts in our laboratory revealed two preparations of soil-derived actinomycetes (H11809 and FH025) with...

Cite
Dahari DE, Salleh RM, Mahmud F, et al. Anti-malarial Activities of Two Soil Actinomycete Isolates from Sabah via Inhibition of Glycogen Synthase Kinase 3β. Trop Life Sci Res. 2016;27(2):53-71doi: 10.21315/tlsr2016.27.2.5.
Dahari, D. E., Salleh, R. M., Mahmud, F., Chin, L. P., Embi, N., & Sidek, H. M. (2016). Anti-malarial Activities of Two Soil Actinomycete Isolates from Sabah via Inhibition of Glycogen Synthase Kinase 3β. Tropical life sciences research, 27(2), 53-71. https://doi.org/10.21315/tlsr2016.27.2.5
Dahari, Dhiana Efani, et al. "Anti-malarial Activities of Two Soil Actinomycete Isolates from Sabah via Inhibition of Glycogen Synthase Kinase 3β." Tropical life sciences research vol. 27,2 (2016): 53-71. doi: https://doi.org/10.21315/tlsr2016.27.2.5
Dahari DE, Salleh RM, Mahmud F, Chin LP, Embi N, Sidek HM. Anti-malarial Activities of Two Soil Actinomycete Isolates from Sabah via Inhibition of Glycogen Synthase Kinase 3β. Trop Life Sci Res. 2016 Aug;27(2):53-71. doi: 10.21315/tlsr2016.27.2.5. PMID: 27688851; PMCID: PMC5031163.
Copy Download .nbib Format: NLM
[No title available]

Journal of medical genetics

Tlemsani C, Luscan A, Leulliot N, Bieth E, Afenjar A, Baujat G, Doco-Fenzy M, Goldenberg A, Lacombe D, Lambert L, Odent S, Pasche J, Sigaudy S, Buffet A, Violle-Poirsier C, Briand-Suleau A, Laurendeau I, Chin M, Saugier-Veber P, Vidaud D, Cormier-Daire V, Vidaud M, Pasmant E, Burglen L.
PMID: 27317772
J Med Genet. 2016 Nov;53(11):743-751. doi: 10.1136/jmedgenet-2015-103638. Epub 2016 Jun 17.

BACKGROUND: Heterozygous METHODS: We aimed at confirming the implication of RESULTS: Six unreported heterozygous likely pathogenic variants in CONCLUSIONS: Our results illustrate the power of targeted NGS to identify rare disease-causing variants. These observations provided evidence for a unifying...

Cite
Tlemsani C, Luscan A, Leulliot N, et al. . J Med Genet. 2016;53(11):743-751doi: 10.1136/jmedgenet-2015-103638.
Tlemsani, C., Luscan, A., Leulliot, N., Bieth, E., Afenjar, A., Baujat, G., Doco-Fenzy, M., Goldenberg, A., Lacombe, D., Lambert, L., Odent, S., Pasche, J., Sigaudy, S., Buffet, A., Violle-Poirsier, C., Briand-Suleau, A., Laurendeau, I., Chin, M., Saugier-Veber, P., Vidaud, D., Cormier-Daire, V., Vidaud, M., Pasmant, E., & Burglen, L. (2016). . Journal of medical genetics, 53(11), 743-751. https://doi.org/10.1136/jmedgenet-2015-103638
Tlemsani, Camille, et al. "." Journal of medical genetics vol. 53,11 (2016): 743-751. doi: https://doi.org/10.1136/jmedgenet-2015-103638
Tlemsani C, Luscan A, Leulliot N, Bieth E, Afenjar A, Baujat G, Doco-Fenzy M, Goldenberg A, Lacombe D, Lambert L, Odent S, Pasche J, Sigaudy S, Buffet A, Violle-Poirsier C, Briand-Suleau A, Laurendeau I, Chin M, Saugier-Veber P, Vidaud D, Cormier-Daire V, Vidaud M, Pasmant E, Burglen L. . J Med Genet. 2016 Nov;53(11):743-751. doi: 10.1136/jmedgenet-2015-103638. Epub 2016 Jun 17. PMID: 27317772.
Copy Download .nbib Format: NLM
Access to and affordability of healthcare for TB patients in China: issues and challenges.

Infectious diseases of poverty

Tang S, Wang L, Wang H, Chin DP.
PMID: 26822583
Infect Dis Poverty. 2016 Jan 29;5:10. doi: 10.1186/s40249-016-0096-y.

This paper introduces the background, aim and objectives of the project entitled "China-the Gates Foundation Collaboration on TB Control in China" that has been underway for many years. It also summarizes the key findings of the nine papers included...

Cite
Tang S, Wang L, Wang H, et al. Access to and affordability of healthcare for TB patients in China: issues and challenges. Infect Dis Poverty. 2016;5:10doi: 10.1186/s40249-016-0096-y.
Tang, S., Wang, L., Wang, H., & Chin, D. P. (2016). Access to and affordability of healthcare for TB patients in China: issues and challenges. Infectious diseases of poverty, 510. https://doi.org/10.1186/s40249-016-0096-y
Tang, Shenglan, et al. "Access to and affordability of healthcare for TB patients in China: issues and challenges." Infectious diseases of poverty vol. 5 (2016): 10. doi: https://doi.org/10.1186/s40249-016-0096-y
Tang S, Wang L, Wang H, Chin DP. Access to and affordability of healthcare for TB patients in China: issues and challenges. Infect Dis Poverty. 2016 Jan 29;5:10. doi: 10.1186/s40249-016-0096-y. PMID: 26822583; PMCID: PMC4731945.
Copy Download .nbib Format: NLM
Super-resolution imaging of nuclear import of adeno-associated virus in live cells.

Molecular therapy. Methods & clinical development

Kelich JM, Ma J, Dong B, Wang Q, Chin M, Magura CM, Xiao W, Yang W.
PMID: 26665132
Mol Ther Methods Clin Dev. 2015 Dec 02;2:15047. doi: 10.1038/mtm.2015.47. eCollection 2015.

Adeno-associated virus (AAV) has been developed as a promising human gene therapy vector. Particularly, recombinant AAV vector (rAAV) achieves its transduction of host cells by crossing at least three physiological barriers including plasma membrane, endosomal membrane, and nuclear envelope...

Cite
Kelich JM, Ma J, Dong B, et al. Super-resolution imaging of nuclear import of adeno-associated virus in live cells. Mol Ther Methods Clin Dev. 2015;2:15047doi: 10.1038/mtm.2015.47.
Kelich, J. M., Ma, J., Dong, B., Wang, Q., Chin, M., Magura, C. M., Xiao, W., & Yang, W. (2015). Super-resolution imaging of nuclear import of adeno-associated virus in live cells. Molecular therapy. Methods & clinical development, 215047. https://doi.org/10.1038/mtm.2015.47
Kelich, Joseph M, et al. "Super-resolution imaging of nuclear import of adeno-associated virus in live cells." Molecular therapy. Methods & clinical development vol. 2 (2015): 15047. doi: https://doi.org/10.1038/mtm.2015.47
Kelich JM, Ma J, Dong B, Wang Q, Chin M, Magura CM, Xiao W, Yang W. Super-resolution imaging of nuclear import of adeno-associated virus in live cells. Mol Ther Methods Clin Dev. 2015 Dec 02;2:15047. doi: 10.1038/mtm.2015.47. eCollection 2015. PMID: 26665132; PMCID: PMC4667716.
Copy Download .nbib Format: NLM
Ethanol Ablation of a Peripheral Nerve Sheath Tumor Presenting as a Small Bowel Obstruction.

ACG case reports journal

Chin M, Chen CL, Chang K, Lee J, Samarasena J.
PMID: 26504873
ACG Case Rep J. 2015 Oct 09;3(1):31-2. doi: 10.14309/crj.2015.92. eCollection 2015 Oct.

Ethanol has historically been used as an ablative agent for a variety of lesions. One of the more common applications of this technique is celiac plexus neurolysis; however, recent reports have suggested a role for the endoscopic alcohol ablation...

Cite
Chin M, Chen CL, Chang K, et al. Ethanol Ablation of a Peripheral Nerve Sheath Tumor Presenting as a Small Bowel Obstruction. ACG Case Rep J. 2015;3(1):31-2doi: 10.14309/crj.2015.92.
Chin, M., Chen, C. L., Chang, K., Lee, J., & Samarasena, J. (2015). Ethanol Ablation of a Peripheral Nerve Sheath Tumor Presenting as a Small Bowel Obstruction. ACG case reports journal, 3(1), 31-2. https://doi.org/10.14309/crj.2015.92
Chin, Matthew, et al. "Ethanol Ablation of a Peripheral Nerve Sheath Tumor Presenting as a Small Bowel Obstruction." ACG case reports journal vol. 3,1 (2015): 31-2. doi: https://doi.org/10.14309/crj.2015.92
Chin M, Chen CL, Chang K, Lee J, Samarasena J. Ethanol Ablation of a Peripheral Nerve Sheath Tumor Presenting as a Small Bowel Obstruction. ACG Case Rep J. 2015 Oct 09;3(1):31-2. doi: 10.14309/crj.2015.92. eCollection 2015 Oct. PMID: 26504873; PMCID: PMC4612753.
Copy Download .nbib Format: NLM
Immunohistochemical and mutational analysis of p53 tumor suppressor gene in gestational trophoblastic disease: correlation with mdm2, proliferation index, and clinicopathologic parameters.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Cheung AN, Shen DH, Khoo US, Chiu MP, Tin VP, Chung LP, Ngan HY.
PMID: 11240753
Int J Gynecol Cancer. 1999 Mar;9(2):123-130. doi: 10.1046/j.1525-1438.1999.09904.x.

The role of p53 in the pathogenesis of gestational trophoblastic disease (GTD) was investigated. Immunohistochemical studies for p53, its regulator mdm2, and proliferation marker Ki67 were performed on paraffin-embedded tissues of 28 partial moles (PM), 57 complete moles (CM),...

Cite
Cheung AN, Shen DH, Khoo US, et al. Immunohistochemical and mutational analysis of p53 tumor suppressor gene in gestational trophoblastic disease: correlation with mdm2, proliferation index, and clinicopathologic parameters. Int J Gynecol Cancer. 1999;9(2):123-130doi: 10.1046/j.1525-1438.1999.09904.x.
Cheung, A. N., Shen, D. H., Khoo, U. S., Chiu, M. P., Tin, V. P., Chung, L. P., & Ngan, H. Y. (1999). Immunohistochemical and mutational analysis of p53 tumor suppressor gene in gestational trophoblastic disease: correlation with mdm2, proliferation index, and clinicopathologic parameters. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 9(2), 123-130. https://doi.org/10.1046/j.1525-1438.1999.09904.x
Cheung, A. N. Y., et al. "Immunohistochemical and mutational analysis of p53 tumor suppressor gene in gestational trophoblastic disease: correlation with mdm2, proliferation index, and clinicopathologic parameters." International journal of gynecological cancer : official journal of the International Gynecological Cancer Society vol. 9,2 (1999): 123-130. doi: https://doi.org/10.1046/j.1525-1438.1999.09904.x
Cheung AN, Shen DH, Khoo US, Chiu MP, Tin VP, Chung LP, Ngan HY. Immunohistochemical and mutational analysis of p53 tumor suppressor gene in gestational trophoblastic disease: correlation with mdm2, proliferation index, and clinicopathologic parameters. Int J Gynecol Cancer. 1999 Mar;9(2):123-130. doi: 10.1046/j.1525-1438.1999.09904.x. PMID: 11240753.
Copy Download .nbib Format: NLM
High-index-contrast waveguides and devices.

Applied optics

Chin MK, Lee CW, Lee SY, Darmawan S.
PMID: 15929301
Appl Opt. 2005 May 20;44(15):3077-86. doi: 10.1364/ao.44.003077.

We present a theoretical and experimental study of high-index-contrast waveguides and basic (passive) devices built from them. Several new results are reported, but to be more comprehensive we also review some of our previous results. We focus on a...

Cite
Chin MK, Lee CW, Lee SY, et al. High-index-contrast waveguides and devices. Appl Opt. 2005;44(15):3077-86doi: 10.1364/ao.44.003077.
Chin, M. K., Lee, C. W., Lee, S. Y., & Darmawan, S. (2005). High-index-contrast waveguides and devices. Applied optics, 44(15), 3077-86. https://doi.org/10.1364/ao.44.003077
Chin, Mee-Koy, et al. "High-index-contrast waveguides and devices." Applied optics vol. 44,15 (2005): 3077-86. doi: https://doi.org/10.1364/ao.44.003077
Chin MK, Lee CW, Lee SY, Darmawan S. High-index-contrast waveguides and devices. Appl Opt. 2005 May 20;44(15):3077-86. doi: 10.1364/ao.44.003077. PMID: 15929301.
Copy Download .nbib Format: NLM
How small can a microring resonator be and yet be polarization independent?.

Applied optics

Ang TY, Lim ST, Lee SY, Png CE, Chin MK.
PMID: 19458730
Appl Opt. 2009 May 20;48(15):2821-35. doi: 10.1364/ao.48.002821.

There has been a recent trend to reduce the size of photonic waveguide devices to enable high-density integration in silicon photonic integrated circuits. However, this miniaturization tends to result in increased polarization dependency. Particularly challenging is designing devices based...

Cite
Ang TY, Lim ST, Lee SY, et al. How small can a microring resonator be and yet be polarization independent?. Appl Opt. 2009;48(15):2821-35doi: 10.1364/ao.48.002821.
Ang, T. Y., Lim, S. T., Lee, S. Y., Png, C. E., & Chin, M. K. (2009). How small can a microring resonator be and yet be polarization independent?. Applied optics, 48(15), 2821-35. https://doi.org/10.1364/ao.48.002821
Ang, Thomas Yong Long, et al. "How small can a microring resonator be and yet be polarization independent?." Applied optics vol. 48,15 (2009): 2821-35. doi: https://doi.org/10.1364/ao.48.002821
Ang TY, Lim ST, Lee SY, Png CE, Chin MK. How small can a microring resonator be and yet be polarization independent?. Appl Opt. 2009 May 20;48(15):2821-35. doi: 10.1364/ao.48.002821. PMID: 19458730.
Copy Download .nbib Format: NLM
The Malaysian consensus statement on utilisation of cardiac CT.

Biomedical imaging and intervention journal

Sim Kh, Abdul Aziz Y, Chin S, Chong F, Choo G, Chew D, Ho E, Chia H, Yusoff M, Ng Kh, Syed Abu Bakar S, Tan Kh, Musa Z.
PMID: 21611020
Biomed Imaging Interv J. 2008 Oct;4(4):e41. doi: 10.2349/biij.4.4.e41. Epub 2008 Oct 01.

No abstract available.

Cite
Sim Kh, Abdul Aziz Y, Chin S, et al. The Malaysian consensus statement on utilisation of cardiac CT. Biomed Imaging Interv J. 2008;4(4):e41doi: 10.2349/biij.4.4.e41.
Sim, K. h., Abdul Aziz, Y., Chin, S., Chong, F., Choo, G., Chew, D., Ho, E., Chia, H., Yusoff, M., Ng, K. h., Syed Abu Bakar, S., Tan, K. h., & Musa, Z. (2008). The Malaysian consensus statement on utilisation of cardiac CT. Biomedical imaging and intervention journal, 4(4), e41. https://doi.org/10.2349/biij.4.4.e41
Sim, Kh, et al. "The Malaysian consensus statement on utilisation of cardiac CT." Biomedical imaging and intervention journal vol. 4,4 (2008): e41. doi: https://doi.org/10.2349/biij.4.4.e41
Sim Kh, Abdul Aziz Y, Chin S, Chong F, Choo G, Chew D, Ho E, Chia H, Yusoff M, Ng Kh, Syed Abu Bakar S, Tan Kh, Musa Z. The Malaysian consensus statement on utilisation of cardiac CT. Biomed Imaging Interv J. 2008 Oct;4(4):e41. doi: 10.2349/biij.4.4.e41. Epub 2008 Oct 01. PMID: 21611020; PMCID: PMC3097749.
Copy Download .nbib Format: NLM
Showing 1 to 12 of 334 entries