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Showing 1 to 12 of 24 entries
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Noninvasive reconstruction of cardiac electrical activity: update on current methods, applications and challenges.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

Cluitmans MJ, Peeters RL, Westra RL, Volders PG.
PMID: 25896779
Neth Heart J. 2015 Jun;23(6):301-11. doi: 10.1007/s12471-015-0690-9.

Electrical activity at the level of the heart muscle can be noninvasively reconstructed from body-surface electrocardiograms (ECGs) and patient-specific torso-heart geometry. This modality, coined electrocardiographic imaging, could fill the gap between the noninvasive (low-resolution) 12-lead ECG and invasive (high-resolution)...

Neuroacanthocytosis: Observations, Theories and Perspectives on the Origin and Significance of Acanthocytes.

Tremor and other hyperkinetic movements (New York, N.Y.)

Adjobo-Hermans MJ, Cluitmans JC, Bosman GJ.
PMID: 26317043
Tremor Other Hyperkinet Mov (N Y). 2015 Aug 25;5:328. doi: 10.7916/D8VH5N2M. eCollection 2015.

The presence of acanthocytes in the blood is characteristic of patients suffering from neuroacanthocytosis (NA). Recent studies have described abnormal phosphorylation of the proteins involved in connecting the membrane and cytoskeleton in patient-derived erythrocytes. The involvement of lipids in...

Multivalent presentation of the cell-penetrating peptide nona-arginine on a linear scaffold strongly increases its membrane-perturbing capacity.

Biochimica et biophysica acta

Chakrabarti A, Witsenburg JJ, Sinzinger MD, Richter M, Wallbrecher R, Cluitmans JC, Verdurmen WP, Tanis S, Adjobo-Hermans MJ, Rademann J, Brock R.
PMID: 25109936
Biochim Biophys Acta. 2014 Dec;1838(12):3097-106. doi: 10.1016/j.bbamem.2014.08.001. Epub 2014 Aug 07.

Arginine-rich cell-penetrating peptides (CPP) are widely employed as delivery vehicles for a large variety of macromolecular cargos. As a mechanism-of-action for induction of uptake cross-linking of heparan sulfates and interaction with lipid head groups have been proposed. Here, we...

Spatiotemporal approximation of cardiac activation and recovery isochrones.

Journal of electrocardiology

Cluitmans M, Coll-Font J, Erem B, Bear L, Nguyên UC, Ter Bekke R, Volders PGA, Brooks D.
PMID: 34979408
J Electrocardiol. 2021 Dec 28;71:1-9. doi: 10.1016/j.jelectrocard.2021.12.007. Epub 2021 Dec 28.

BACKGROUND: The sequence of myocardial activation and recovery can be studied in detail by invasive catheter recordings of cardiac electrograms (EGMs), or noninvasive inverse reconstructions thereof with electrocardiographic imaging (ECGI). Local activation and recovery times are obtained from a...

Spatiotemporal approximation of cardiac activation and recovery isochrones.

Journal of electrocardiology

Cluitmans M, Coll-Font J, Erem B, Bear L, Nguyên UC, Ter Bekke R, Volders PGA, Brooks D.
PMID: 34979408
J Electrocardiol. 2021 Dec 28;71:1-9. doi: 10.1016/j.jelectrocard.2021.12.007. Epub 2021 Dec 28.

BACKGROUND: The sequence of myocardial activation and recovery can be studied in detail by invasive catheter recordings of cardiac electrograms (EGMs), or noninvasive inverse reconstructions thereof with electrocardiographic imaging (ECGI). Local activation and recovery times are obtained from a...

Electrocardiographic Imaging for Atrial Fibrillation: A Perspective From Computer Models and Animal Experiments to Clinical Value.

Frontiers in physiology

Salinet J, Molero R, Schlindwein FS, Karel J, Rodrigo M, Rojo-Álvarez JL, Berenfeld O, Climent AM, Zenger B, Vanheusden F, Paredes JGS, MacLeod R, Atienza F, Guillem MS, Cluitmans M, Bonizzi P.
PMID: 33995122
Front Physiol. 2021 Apr 30;12:653013. doi: 10.3389/fphys.2021.653013. eCollection 2021.

Electrocardiographic imaging (ECGI) is a technique to reconstruct non-invasively the electrical activity on the heart surface from body-surface potential recordings and geometric information of the torso and the heart. ECGI has shown scientific and clinical value when used to...

Comparison of Activation Times Estimation for Potential-Based ECG Imaging.

Computing in cardiology

Schaufelberger M, Schuler S, Bear L, Cluitmans M, Coll-Font J, Onak ÖN, Dössel O, Brooks D.
PMID: 32190705
Comput Cardiol (2010). 2019 Sep;46. doi: 10.22489/cinc.2019.379. Epub 2020 Feb 24.

Activation times (AT) describe the sequence of cardiac depolarization and represent one of the most important parameters for analysis of cardiac electrical activity. However, estimation of ATs can be challenging due to multiple sources of noise such as fractionation...

Spatiotemporal approximation of cardiac activation and recovery isochrones.

Journal of electrocardiology

Cluitmans M, Coll-Font J, Erem B, Bear L, Nguyên UC, Ter Bekke R, Volders PGA, Brooks D.
PMID: 34979408
J Electrocardiol. 2021 Dec 28;71:1-9. doi: 10.1016/j.jelectrocard.2021.12.007. Epub 2021 Dec 28.

BACKGROUND: The sequence of myocardial activation and recovery can be studied in detail by invasive catheter recordings of cardiac electrograms (EGMs), or noninvasive inverse reconstructions thereof with electrocardiographic imaging (ECGI). Local activation and recovery times are obtained from a...

Body Surface Mapping of Ventricular Repolarization Heterogeneity: An .

Frontiers in physiology

Meo M, Bonizzi P, Bear LR, Cluitmans M, Abell E, Haïssaguerre M, Bernus O, Dubois R.
PMID: 32903614
Front Physiol. 2020 Aug 13;11:933. doi: 10.3389/fphys.2020.00933. eCollection 2020.

BACKGROUND: Increased heterogeneity of ventricular repolarization is associated with life-threatening arrhythmia and sudden cardiac death (SCD). T-wave analysis through body surface potential mapping (BSPM) is a promising tool for risk stratification, but the clinical effectiveness of current electrocardiographic indices...

Reply to the letter from Bhagirath et al.: Imaging for cardiac resynchronisation therapy requires cardiac magnetic resonance.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

Nguyên UC, Cluitmans MJM, Prinzen FW, Mihl C, Vernooy K.
PMID: 30406603
Neth Heart J. 2018 Dec;26(12):641-642. doi: 10.1007/s12471-018-1196-z.

No abstract available.

Adriaan van Oosterom, PhD.

Heart rhythm

Oostendorp TF, Cluitmans M, Coronel R, Dubois R.
PMID: 31570142
Heart Rhythm. 2019 Oct;16(10):e299. doi: 10.1016/j.hrthm.2019.06.010.

No abstract available.

Validation and Opportunities of Electrocardiographic Imaging: From Technical Achievements to Clinical Applications.

Frontiers in physiology

Cluitmans M, Brooks DH, MacLeod R, Dössel O, Guillem MS, van Dam PM, Svehlikova J, He B, Sapp J, Wang L, Bear L.
PMID: 30294281
Front Physiol. 2018 Sep 20;9:1305. doi: 10.3389/fphys.2018.01305. eCollection 2018.

Electrocardiographic imaging (ECGI) reconstructs the electrical activity of the heart from a dense array of body-surface electrocardiograms and a patient-specific heart-torso geometry. Depending on how it is formulated, ECGI allows the reconstruction of the activation and recovery sequence of...

Showing 1 to 12 of 24 entries