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Aromatherapy and Aromatic Plants for the Treatment of Behavioural and Psychological Symptoms of Dementia in Patients with Alzheimer's Disease: Clinical Evidence and Possible Mechanisms.

Evidence-based complementary and alternative medicine : eCAM

Scuteri D, Morrone LA, Rombolà L, Avato PR, Bilia AR, Corasaniti MT, Sakurada S, Sakurada T, Bagetta G.
PMID: 28465709
Evid Based Complement Alternat Med. 2017;2017:9416305. doi: 10.1155/2017/9416305. Epub 2017 Mar 30.

The treatment of agitation and aggression, typical Behavioural and Psychological Symptoms of Dementia (BPSDs) of Alzheimer's Disease (AD), is one of the most complicated aspects of handling patients suffering from dementia. Currently, the management of these symptoms often associated...

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Scuteri D, Morrone LA, Rombolà L, et al. Aromatherapy and Aromatic Plants for the Treatment of Behavioural and Psychological Symptoms of Dementia in Patients with Alzheimer's Disease: Clinical Evidence and Possible Mechanisms. Evid Based Complement Alternat Med. 2017;2017:9416305doi: 10.1155/2017/9416305.
Scuteri, D., Morrone, L. A., Rombolà, L., Avato, P. R., Bilia, A. R., Corasaniti, M. T., Sakurada, S., Sakurada, T., & Bagetta, G. (2017). Aromatherapy and Aromatic Plants for the Treatment of Behavioural and Psychological Symptoms of Dementia in Patients with Alzheimer's Disease: Clinical Evidence and Possible Mechanisms. Evidence-based complementary and alternative medicine : eCAM, 20179416305. https://doi.org/10.1155/2017/9416305
Scuteri, Damiana, et al. "Aromatherapy and Aromatic Plants for the Treatment of Behavioural and Psychological Symptoms of Dementia in Patients with Alzheimer's Disease: Clinical Evidence and Possible Mechanisms." Evidence-based complementary and alternative medicine : eCAM vol. 2017 (2017): 9416305. doi: https://doi.org/10.1155/2017/9416305
Scuteri D, Morrone LA, Rombolà L, Avato PR, Bilia AR, Corasaniti MT, Sakurada S, Sakurada T, Bagetta G. Aromatherapy and Aromatic Plants for the Treatment of Behavioural and Psychological Symptoms of Dementia in Patients with Alzheimer's Disease: Clinical Evidence and Possible Mechanisms. Evid Based Complement Alternat Med. 2017;2017:9416305. doi: 10.1155/2017/9416305. Epub 2017 Mar 30. PMID: 28465709; PMCID: PMC5390566.
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Model-independent dark energy differentiation with the integrated Sachs-Wolfe effect.

Physical review letters

Corasaniti PS, Bassett BA, Ungarelli C, Copeland EJ.
PMID: 12689211
Phys Rev Lett. 2003 Mar 07;90(9):091303. doi: 10.1103/PhysRevLett.90.091303. Epub 2003 Mar 07.

We study the integrated Sachs-Wolfe effect using a model-independent parametrization of the dark energy equation of state, w(z). Cosmic variance severely restricts the class of models distinguishable from one based on cold dark matter and a cosmological constant unless...

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Corasaniti PS, Bassett BA, Ungarelli C, et al. Model-independent dark energy differentiation with the integrated Sachs-Wolfe effect. Phys Rev Lett. 2003;90(9):091303doi: 10.1103/PhysRevLett.90.091303.
Corasaniti, P. S., Bassett, B. A., Ungarelli, C., & Copeland, E. J. (2003). Model-independent dark energy differentiation with the integrated Sachs-Wolfe effect. Physical review letters, 90(9), 091303. https://doi.org/10.1103/PhysRevLett.90.091303
Corasaniti, P S, et al. "Model-independent dark energy differentiation with the integrated Sachs-Wolfe effect." Physical review letters vol. 90,9 (2003): 091303. doi: https://doi.org/10.1103/PhysRevLett.90.091303
Corasaniti PS, Bassett BA, Ungarelli C, Copeland EJ. Model-independent dark energy differentiation with the integrated Sachs-Wolfe effect. Phys Rev Lett. 2003 Mar 07;90(9):091303. doi: 10.1103/PhysRevLett.90.091303. Epub 2003 Mar 07. PMID: 12689211.
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Evidence for accuracy of pain assessment and painkillers utilization in neuropsychiatric symptoms of dementia in Calabria region, Italy.

Neural regeneration research

Scuteri D, Garreffa MR, Esposito S, Bagetta G, Naturale MD, Corasaniti MT.
PMID: 30127123
Neural Regen Res. 2018 Sep;13(9):1619-1621. doi: 10.4103/1673-5374.237125.

During the clinical course of dementia, beside cognitive impairment and memory loss, a very complex challenge is posed by the neuropsychiatric symptoms (NPSs). Accurate evaluation and treatment of pain impacts positively the agitation of demented patients aged ≥ 65...

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Scuteri D, Garreffa MR, Esposito S, et al. Evidence for accuracy of pain assessment and painkillers utilization in neuropsychiatric symptoms of dementia in Calabria region, Italy. Neural Regen Res. 2018;13(9):1619-1621doi: 10.4103/1673-5374.237125.
Scuteri, D., Garreffa, M. R., Esposito, S., Bagetta, G., Naturale, M. D., & Corasaniti, M. T. (2018). Evidence for accuracy of pain assessment and painkillers utilization in neuropsychiatric symptoms of dementia in Calabria region, Italy. Neural regeneration research, 13(9), 1619-1621. https://doi.org/10.4103/1673-5374.237125
Scuteri, Damiana, et al. "Evidence for accuracy of pain assessment and painkillers utilization in neuropsychiatric symptoms of dementia in Calabria region, Italy." Neural regeneration research vol. 13,9 (2018): 1619-1621. doi: https://doi.org/10.4103/1673-5374.237125
Scuteri D, Garreffa MR, Esposito S, Bagetta G, Naturale MD, Corasaniti MT. Evidence for accuracy of pain assessment and painkillers utilization in neuropsychiatric symptoms of dementia in Calabria region, Italy. Neural Regen Res. 2018 Sep;13(9):1619-1621. doi: 10.4103/1673-5374.237125. PMID: 30127123; PMCID: PMC6126116.
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New trends in pharmacological control of neuropsychiatric symptoms of dementia.

Current opinion in pharmacology

Scuteri D, Corasaniti MT, Tonin P, Nicotera P, Bagetta G.
PMID: 34634603
Curr Opin Pharmacol. 2021 Dec;61:69-76. doi: 10.1016/j.coph.2021.09.002. Epub 2021 Oct 09.

Abnormal neuronal and synaptic plasticity occurs in Alzheimer's disease (AD) and depression. The latter, particularly late-life, has been recognized as fundamental in the identification of at-risk prodromal stages of AD. The lack of disease-modifying drugs and the off-label use...

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Scuteri D, Corasaniti MT, Tonin P, et al. New trends in pharmacological control of neuropsychiatric symptoms of dementia. Curr Opin Pharmacol. 2021;61:69-76doi: 10.1016/j.coph.2021.09.002.
Scuteri, D., Corasaniti, M. T., Tonin, P., Nicotera, P., & Bagetta, G. (2021). New trends in pharmacological control of neuropsychiatric symptoms of dementia. Current opinion in pharmacology, 6169-76. https://doi.org/10.1016/j.coph.2021.09.002
Scuteri, Damiana, et al. "New trends in pharmacological control of neuropsychiatric symptoms of dementia." Current opinion in pharmacology vol. 61 (2021): 69-76. doi: https://doi.org/10.1016/j.coph.2021.09.002
Scuteri D, Corasaniti MT, Tonin P, Nicotera P, Bagetta G. New trends in pharmacological control of neuropsychiatric symptoms of dementia. Curr Opin Pharmacol. 2021 Dec;61:69-76. doi: 10.1016/j.coph.2021.09.002. Epub 2021 Oct 09. PMID: 34634603.
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Is there a rational basis for cannabinoids research and development in ocular pain therapy? A systematic review of preclinical evidence.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Scuteri D, Rombolà L, Hamamura K, Sakurada T, Watanabe C, Sakurada S, Guida F, Boccella S, Maione S, Gallo Afflitto G, Nucci C, Tonin P, Bagetta G, Corasaniti MT.
PMID: 34891121
Biomed Pharmacother. 2021 Dec 07;146:112505. doi: 10.1016/j.biopha.2021.112505. Epub 2021 Dec 07.

BACKGROUND: Purpose of the present systematic review is to investigate preclinical evidence in favor of the working hypothesis of efficacy of cannabinoids in ocular pain treatment.METHODS: Literature search includes the most relevant repositories for medical scientific literature from inception...

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Scuteri D, Rombolà L, Hamamura K, et al. Is there a rational basis for cannabinoids research and development in ocular pain therapy? A systematic review of preclinical evidence. Biomed Pharmacother. 2021;146:112505doi: 10.1016/j.biopha.2021.112505.
Scuteri, D., Rombolà, L., Hamamura, K., Sakurada, T., Watanabe, C., Sakurada, S., Guida, F., Boccella, S., Maione, S., Gallo Afflitto, G., Nucci, C., Tonin, P., Bagetta, G., & Corasaniti, M. T. (2021). Is there a rational basis for cannabinoids research and development in ocular pain therapy? A systematic review of preclinical evidence. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 146112505. https://doi.org/10.1016/j.biopha.2021.112505
Scuteri, D, et al. "Is there a rational basis for cannabinoids research and development in ocular pain therapy? A systematic review of preclinical evidence." Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol. 146 (2021): 112505. doi: https://doi.org/10.1016/j.biopha.2021.112505
Scuteri D, Rombolà L, Hamamura K, Sakurada T, Watanabe C, Sakurada S, Guida F, Boccella S, Maione S, Gallo Afflitto G, Nucci C, Tonin P, Bagetta G, Corasaniti MT. Is there a rational basis for cannabinoids research and development in ocular pain therapy? A systematic review of preclinical evidence. Biomed Pharmacother. 2021 Dec 07;146:112505. doi: 10.1016/j.biopha.2021.112505. Epub 2021 Dec 07. PMID: 34891121.
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Is there a rational basis for cannabinoids research and development in ocular pain therapy? A systematic review of preclinical evidence.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Scuteri D, Rombolà L, Hamamura K, Sakurada T, Watanabe C, Sakurada S, Guida F, Boccella S, Maione S, Gallo Afflitto G, Nucci C, Tonin P, Bagetta G, Corasaniti MT.
PMID: 34891121
Biomed Pharmacother. 2021 Dec 07;146:112505. doi: 10.1016/j.biopha.2021.112505. Epub 2021 Dec 07.

BACKGROUND: Purpose of the present systematic review is to investigate preclinical evidence in favor of the working hypothesis of efficacy of cannabinoids in ocular pain treatment.METHODS: Literature search includes the most relevant repositories for medical scientific literature from inception...

Cite
Scuteri D, Rombolà L, Hamamura K, et al. Is there a rational basis for cannabinoids research and development in ocular pain therapy? A systematic review of preclinical evidence. Biomed Pharmacother. 2021;146:112505doi: 10.1016/j.biopha.2021.112505.
Scuteri, D., Rombolà, L., Hamamura, K., Sakurada, T., Watanabe, C., Sakurada, S., Guida, F., Boccella, S., Maione, S., Gallo Afflitto, G., Nucci, C., Tonin, P., Bagetta, G., & Corasaniti, M. T. (2021). Is there a rational basis for cannabinoids research and development in ocular pain therapy? A systematic review of preclinical evidence. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 146112505. https://doi.org/10.1016/j.biopha.2021.112505
Scuteri, D, et al. "Is there a rational basis for cannabinoids research and development in ocular pain therapy? A systematic review of preclinical evidence." Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol. 146 (2021): 112505. doi: https://doi.org/10.1016/j.biopha.2021.112505
Scuteri D, Rombolà L, Hamamura K, Sakurada T, Watanabe C, Sakurada S, Guida F, Boccella S, Maione S, Gallo Afflitto G, Nucci C, Tonin P, Bagetta G, Corasaniti MT. Is there a rational basis for cannabinoids research and development in ocular pain therapy? A systematic review of preclinical evidence. Biomed Pharmacother. 2021 Dec 07;146:112505. doi: 10.1016/j.biopha.2021.112505. Epub 2021 Dec 07. PMID: 34891121.
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Exploitation of Thermal Sensitivity and Hyperalgesia in a Mouse Model of Dystonia.

Life (Basel, Switzerland)

Scuteri D, Rombolà L, Natoli S, Pisani A, Bonsi P, Hamamura K, Bagetta G, Tonin P, Corasaniti MT.
PMID: 34575134
Life (Basel). 2021 Sep 19;11(9). doi: 10.3390/life11090985.

Neuropathic pain is characterized by mechanical allodynia and thermal hyperalgesia to heat, and it affects some 20% of European population. Patients suffering from several neurologic diseases experience neuropathic pain, often finding no relief in therapy. Transgenic mice expressing the...

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Scuteri D, Rombolà L, Natoli S, et al. Exploitation of Thermal Sensitivity and Hyperalgesia in a Mouse Model of Dystonia. Life (Basel). 2021;11(9)doi: 10.3390/life11090985.
Scuteri, D., Rombolà, L., Natoli, S., Pisani, A., Bonsi, P., Hamamura, K., Bagetta, G., Tonin, P., & Corasaniti, M. T. (2021). Exploitation of Thermal Sensitivity and Hyperalgesia in a Mouse Model of Dystonia. Life (Basel, Switzerland), 11(9), . https://doi.org/10.3390/life11090985
Scuteri, Damiana, et al. "Exploitation of Thermal Sensitivity and Hyperalgesia in a Mouse Model of Dystonia." Life (Basel, Switzerland) vol. 11,9 (2021). doi: https://doi.org/10.3390/life11090985
Scuteri D, Rombolà L, Natoli S, Pisani A, Bonsi P, Hamamura K, Bagetta G, Tonin P, Corasaniti MT. Exploitation of Thermal Sensitivity and Hyperalgesia in a Mouse Model of Dystonia. Life (Basel). 2021 Sep 19;11(9). doi: 10.3390/life11090985. PMID: 34575134; PMCID: PMC8468866.
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Azithromycin Affords Neuroprotection in Rat Undergone Transient Focal Cerebral Ischemia.

Frontiers in neuroscience

Amantea D, Petrelli F, Greco R, Tassorelli C, Corasaniti MT, Tonin P, Bagetta G.
PMID: 31849581
Front Neurosci. 2019 Nov 26;13:1256. doi: 10.3389/fnins.2019.01256. eCollection 2019.

Repurposing existing drugs represents a promising approach for successful development of acute stroke therapies. In this context, the macrolide antibiotic azithromycin has been shown to exert neuroprotection in mice due to its immunomodulatory properties. Here, we have demonstrated that...

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Amantea D, Petrelli F, Greco R, et al. Azithromycin Affords Neuroprotection in Rat Undergone Transient Focal Cerebral Ischemia. Front Neurosci. 2019;13:1256doi: 10.3389/fnins.2019.01256.
Amantea, D., Petrelli, F., Greco, R., Tassorelli, C., Corasaniti, M. T., Tonin, P., & Bagetta, G. (2019). Azithromycin Affords Neuroprotection in Rat Undergone Transient Focal Cerebral Ischemia. Frontiers in neuroscience, 131256. https://doi.org/10.3389/fnins.2019.01256
Amantea, Diana, et al. "Azithromycin Affords Neuroprotection in Rat Undergone Transient Focal Cerebral Ischemia." Frontiers in neuroscience vol. 13 (2019): 1256. doi: https://doi.org/10.3389/fnins.2019.01256
Amantea D, Petrelli F, Greco R, Tassorelli C, Corasaniti MT, Tonin P, Bagetta G. Azithromycin Affords Neuroprotection in Rat Undergone Transient Focal Cerebral Ischemia. Front Neurosci. 2019 Nov 26;13:1256. doi: 10.3389/fnins.2019.01256. eCollection 2019. PMID: 31849581; PMCID: PMC6902046.
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Spin-Canting-Induced Band Reconstruction in the Dirac Material Ca_{1-x}Na_{x}MnBi_{2}.

Physical review letters

Yang R, Corasaniti M, Le CC, Liao ZY, Wang AF, Du Q, Petrovic C, Qiu XG, Hu JP, Degiorgi L.
PMID: 32302196
Phys Rev Lett. 2020 Apr 03;124(13):137201. doi: 10.1103/PhysRevLett.124.137201.

The ternary AMnBi_{2} (A is alkaline as well as rare-earth atom) materials provide an arena for investigating the interplay between low-dimensional magnetism of the antiferromagnetic MnBi layers and the electronic states in the intercalated Bi layers, which harbor relativistic...

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Yang R, Corasaniti M, Le CC, et al. Spin-Canting-Induced Band Reconstruction in the Dirac Material Ca_{1-x}Na_{x}MnBi_{2}. Phys Rev Lett. 2020;124(13):137201doi: 10.1103/PhysRevLett.124.137201.
Yang, R., Corasaniti, M., Le, C. C., Liao, Z. Y., Wang, A. F., Du, Q., Petrovic, C., Qiu, X. G., Hu, J. P., & Degiorgi, L. (2020). Spin-Canting-Induced Band Reconstruction in the Dirac Material Ca_{1-x}Na_{x}MnBi_{2}. Physical review letters, 124(13), 137201. https://doi.org/10.1103/PhysRevLett.124.137201
Yang, R, et al. "Spin-Canting-Induced Band Reconstruction in the Dirac Material Ca_{1-x}Na_{x}MnBi_{2}." Physical review letters vol. 124,13 (2020): 137201. doi: https://doi.org/10.1103/PhysRevLett.124.137201
Yang R, Corasaniti M, Le CC, Liao ZY, Wang AF, Du Q, Petrovic C, Qiu XG, Hu JP, Degiorgi L. Spin-Canting-Induced Band Reconstruction in the Dirac Material Ca_{1-x}Na_{x}MnBi_{2}. Phys Rev Lett. 2020 Apr 03;124(13):137201. doi: 10.1103/PhysRevLett.124.137201. PMID: 32302196.
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Is there a rational basis for cannabinoids research and development in ocular pain therapy? A systematic review of preclinical evidence.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Scuteri D, Rombolà L, Hamamura K, Sakurada T, Watanabe C, Sakurada S, Guida F, Boccella S, Maione S, Gallo Afflitto G, Nucci C, Tonin P, Bagetta G, Corasaniti MT.
PMID: 34891121
Biomed Pharmacother. 2021 Dec 07;146:112505. doi: 10.1016/j.biopha.2021.112505. Epub 2021 Dec 07.

BACKGROUND: Purpose of the present systematic review is to investigate preclinical evidence in favor of the working hypothesis of efficacy of cannabinoids in ocular pain treatment.METHODS: Literature search includes the most relevant repositories for medical scientific literature from inception...

Cite
Scuteri D, Rombolà L, Hamamura K, et al. Is there a rational basis for cannabinoids research and development in ocular pain therapy? A systematic review of preclinical evidence. Biomed Pharmacother. 2021;146:112505doi: 10.1016/j.biopha.2021.112505.
Scuteri, D., Rombolà, L., Hamamura, K., Sakurada, T., Watanabe, C., Sakurada, S., Guida, F., Boccella, S., Maione, S., Gallo Afflitto, G., Nucci, C., Tonin, P., Bagetta, G., & Corasaniti, M. T. (2021). Is there a rational basis for cannabinoids research and development in ocular pain therapy? A systematic review of preclinical evidence. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 146112505. https://doi.org/10.1016/j.biopha.2021.112505
Scuteri, D, et al. "Is there a rational basis for cannabinoids research and development in ocular pain therapy? A systematic review of preclinical evidence." Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol. 146 (2021): 112505. doi: https://doi.org/10.1016/j.biopha.2021.112505
Scuteri D, Rombolà L, Hamamura K, Sakurada T, Watanabe C, Sakurada S, Guida F, Boccella S, Maione S, Gallo Afflitto G, Nucci C, Tonin P, Bagetta G, Corasaniti MT. Is there a rational basis for cannabinoids research and development in ocular pain therapy? A systematic review of preclinical evidence. Biomed Pharmacother. 2021 Dec 07;146:112505. doi: 10.1016/j.biopha.2021.112505. Epub 2021 Dec 07. PMID: 34891121.
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The Role of Autophagy in Glaucomatous Optic Neuropathy.

Frontiers in cell and developmental biology

Adornetto A, Parisi V, Morrone LA, Corasaniti MT, Bagetta G, Tonin P, Russo R.
PMID: 32211404
Front Cell Dev Biol. 2020 Mar 04;8:121. doi: 10.3389/fcell.2020.00121. eCollection 2020.

Autophagy is a conserved lysosomal-dependent pathway responsible for the degradation of cytoplasmic macromolecules. Based on the mechanism of cargo delivery to lysosomes, mammalian cells can undergo micro, macro, and chaperone-mediated autophagy. Other than physiological turnover of proteins and organelles,...

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Adornetto A, Parisi V, Morrone LA, et al. The Role of Autophagy in Glaucomatous Optic Neuropathy. Front Cell Dev Biol. 2020;8:121doi: 10.3389/fcell.2020.00121.
Adornetto, A., Parisi, V., Morrone, L. A., Corasaniti, M. T., Bagetta, G., Tonin, P., & Russo, R. (2020). The Role of Autophagy in Glaucomatous Optic Neuropathy. Frontiers in cell and developmental biology, 8121. https://doi.org/10.3389/fcell.2020.00121
Adornetto, Annagrazia, et al. "The Role of Autophagy in Glaucomatous Optic Neuropathy." Frontiers in cell and developmental biology vol. 8 (2020): 121. doi: https://doi.org/10.3389/fcell.2020.00121
Adornetto A, Parisi V, Morrone LA, Corasaniti MT, Bagetta G, Tonin P, Russo R. The Role of Autophagy in Glaucomatous Optic Neuropathy. Front Cell Dev Biol. 2020 Mar 04;8:121. doi: 10.3389/fcell.2020.00121. eCollection 2020. PMID: 32211404; PMCID: PMC7066980.
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Exploitation of cytotoxicity of some essential oils for translation in cancer therapy.

Evidence-based complementary and alternative medicine : eCAM

Russo R, Corasaniti MT, Bagetta G, Morrone LA.
PMID: 25722735
Evid Based Complement Alternat Med. 2015;2015:397821. doi: 10.1155/2015/397821. Epub 2015 Feb 04.

Essential oils are complex mixtures of several components endowed with a wide range of biological activities, including antiseptic, anti-inflammatory, spasmolytic, sedative, analgesic, and anesthetic properties. A growing body of scientific reports has recently focused on the potential of essential...

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Russo R, Corasaniti MT, Bagetta G, et al. Exploitation of cytotoxicity of some essential oils for translation in cancer therapy. Evid Based Complement Alternat Med. 2015;2015:397821doi: 10.1155/2015/397821.
Russo, R., Corasaniti, M. T., Bagetta, G., & Morrone, L. A. (2015). Exploitation of cytotoxicity of some essential oils for translation in cancer therapy. Evidence-based complementary and alternative medicine : eCAM, 2015397821. https://doi.org/10.1155/2015/397821
Russo, Rossella, et al. "Exploitation of cytotoxicity of some essential oils for translation in cancer therapy." Evidence-based complementary and alternative medicine : eCAM vol. 2015 (2015): 397821. doi: https://doi.org/10.1155/2015/397821
Russo R, Corasaniti MT, Bagetta G, Morrone LA. Exploitation of cytotoxicity of some essential oils for translation in cancer therapy. Evid Based Complement Alternat Med. 2015;2015:397821. doi: 10.1155/2015/397821. Epub 2015 Feb 04. PMID: 25722735; PMCID: PMC4334976.
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