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The Synthesis of Methyl-Substituted Spirocyclic Piperidine-Azetidine (2,7-Diazaspiro[3.5]nonane) and Spirocyclic Piperidine-Pyrrolidine (2,8-Diazaspiro[4.5]decane) Ring Systems.

The Journal of organic chemistry

Smith AC, Cabral S, Kung DW, Rose CR, Southers JA, García-Irizarry CN, Damon DB, Bagley SW, Griffith DA.
PMID: 27056793
J Org Chem. 2016 May 06;81(9):3509-19. doi: 10.1021/acs.joc.5b02890. Epub 2016 Apr 25.

The synthesis of a series of pharmaceutically important N-protected methyl-substituted spirocyclic piperidine-azetidine (2,7-diazaspiro[3.5]nonane) and spirocyclic piperidine-pyrrolidine (2,8-diazaspiro[4.5]decane) ring systems was developed. These motifs contain two differentiated sites (protected secondary amines) to allow for further functionalization via reductive amination, amidation,...

Author's reply to Woodward.

BMJ (Clinical research ed.)

Damen JA.
PMID: 27530225
BMJ. 2016 Aug 16;354:i4485. doi: 10.1136/bmj.i4485.

No abstract available.

Storm-Related Carbon Monoxide Poisoning: An Investigation of Target Audience Knowledge and Risk Behaviors.

Social marketing quarterly

Damon SA, Poehlman JA, Rupert DJ, Williams PN.
PMID: 26345640
Soc Mar Q. 2013;19(3):188. doi: 10.1177/1524500413493426.

Carbon monoxide (CO) poisonings in the United States consistently occur when residents improperly use portable gasoline-powered generators and other tools following severe storms and power outages. However, protective behaviors-such as installing CO alarms and placing generators more than 20...

Application of scanning angle Raman spectroscopy for determining the location of buried polymer interfaces with tens of nanometer precision.

The Analyst

Damin CA, Nguyen VH, Niyibizi AS, Smith EA.
PMID: 25669718
Analyst. 2015 Mar 21;140(6):1955-64. doi: 10.1039/c4an02240h.

Near-infrared scanning angle (SA) Raman spectroscopy was utilized to determine the interface location in bilayer films (a stack of two polymer layers) of polystyrene (PS) and polycarbonate (PC). Finite-difference-time-domain (FDTD) calculations of the sum square electric field (SSEF) for...

Enforced Layer-by-Layer Stacking of Energetic Salts towards High-Performance Insensitive Energetic Materials.

Journal of the American Chemical Society

Zhang J, Mitchell LA, Parrish DA, Shreeve JM.
PMID: 26262555
J Am Chem Soc. 2015 Aug 26;137(33):10532-5. doi: 10.1021/jacs.5b07852. Epub 2015 Aug 14.

Development of modern high-performance insensitive energetic materials is significant because of the increasing demands for both military and civilian applications. Here we propose a rapid and facile strategy called the "layer hydrogen bonding pairing approach" to organize energetic molecules...

Comparative Study of Various Pyrazole-based Anions: A Promising Family of Ionic Derivatives as Insensitive Energetic Materials.

Chemistry, an Asian journal

Yin P, Mitchell LA, Parrish DA, Shreeve JM.
PMID: 28042911
Chem Asian J. 2017 Feb 01;12(3):378-384. doi: 10.1002/asia.201601615. Epub 2017 Jan 09.

In the design of advanced energetic materials, high-density explosophores play a pivotal role because of their remarkable enhancement of both density and molecular stability. Using diversified functionalization strategies, a comparative study involving various nitropyrazole anions shows that these are...

Energetic Salts Based on 3,5-Bis(dinitromethyl)-1,2,4-triazole Monoanion and Dianion: Controllable Preparation, Characterization, and High Performance.

Journal of the American Chemical Society

Zhang J, Dharavath S, Mitchell LA, Parrish DA, Shreeve JM.
PMID: 27267735
J Am Chem Soc. 2016 Jun 22;138(24):7500-3. doi: 10.1021/jacs.6b03819. Epub 2016 Jun 10.

Molecular modification of known explosives is considered to be an efficient route to design new energetic materials. A new family of energetic salts based on the 3,5-bis(dinitromethyl)-1,2,4-triazole monoanion and dianion were controllably synthesized by using 1-diamino-2,2-dinitroethene as a precursor....

2D wax-printed paper substrates with extended solvent supply capabilities allow enhanced ion signal in paper spray ionization.

The Analyst

Damon DE, Maher YS, Yin M, Jjunju FP, Young IS, Taylor S, Maher S, Badu-Tawiah AK.
PMID: 27121269
Analyst. 2016 Jun 21;141(12):3866-73. doi: 10.1039/c6an00168h. Epub 2016 Apr 28.

Paper-based microfluidic channels were created from solid wax printing, and the resultant 2D wax-printed paper substrates were used for paper spray (PS) mass spectrometry (MS) analysis of small organic compounds. Controlling fluid flow at the tip of the wax-printed...

Nitromethane Bridged Bis(1,3,4-oxadiazoles): Trianionic Energetic Salts with Low Sensitivities.

Chemistry (Weinheim an der Bergstrasse, Germany)

Yu Q, Imler GH, Parrish DA, Shreeve JM.
PMID: 29124792
Chemistry. 2017 Dec 14;23(70):17682-17686. doi: 10.1002/chem.201704939. Epub 2017 Nov 28.

Trianionic energetic salts based on one nitromethylene and two dinitromethyl anions were designed and synthesized. Interestingly, the unstable dinitromethylene group of diethyl 2,2'-((dinitromethylene)bis(1,3,4-oxadiazole-5,2-diyl))bis(2,2-dinitroacetate) (2) was changed to a mononitromethylene group by an aminolysis reaction to form triammonium ((nitromethanidylene)bis(1,3,4-oxadiazole-5,2-diyl))bis(dinitromethanide) (3),...

Mono- and diiodo-1,2,3-triazoles and their mono nitro derivatives.

Dalton transactions (Cambridge, England : 2003)

Chand D, He C, Hooper JP, Mitchell LA, Parrish DA, Shreeve JM.
PMID: 27226283
Dalton Trans. 2016 Jun 21;45(23):9684-8. doi: 10.1039/c6dt01731b. Epub 2016 May 26.

4-Iodo-1H-1,2,3-triazole (2) and 4,5-diiodo-1H-1,2,3-triazole (3) were synthesized using an efficient and viable synthetic route. The N-alkylation of 3 resulted in the formation of two tautomers. The N-alkyl-diiodo-triazoles were nitrated with 100% nitric acid to form monoiodo-mononitro-triazoles. The structures of...

Energetic salts with π-stacking and hydrogen-bonding interactions lead the way to future energetic materials.

Journal of the American Chemical Society

Zhang J, Zhang Q, Vo TT, Parrish DA, Shreeve JM.
PMID: 25565429
J Am Chem Soc. 2015 Feb 04;137(4):1697-704. doi: 10.1021/ja5126275. Epub 2015 Jan 23.

Among energetic materials, there are two significant challenges facing researchers: 1) to develop ionic CHNO explosives with higher densities than their parent nonionic molecules and (2) to achieve a fine balance between high detonation performance and low sensitivity. We...

Correction for Kondas et al., Variola Virus-Specific Diagnostic Assays: Characterization, Sensitivity, and Specificity.

Journal of clinical microbiology

Kondas AV, Olson VA, Li Y, Abel J, Laker M, Rose L, Wilkins K, Turner J, Kline R, Damon IK.
PMID: 26195639
J Clin Microbiol. 2015 Aug;53(8):2795. doi: 10.1128/JCM.01383-15.

No abstract available.

Showing 1 to 12 of 274 entries