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Precision therapy for a new disorder of AMPA receptor recycling due to mutations in .

Neurology. Genetics

Ahrens-Nicklas RC, Umanah GK, Sondheimer N, Deardorff MA, Wilkens AB, Conlin LK, Santani AB, Nesbitt A, Juulsola J, Ma E, Dawson TM, Dawson VL, Marsh ED.
PMID: 28180185
Neurol Genet. 2017 Feb 01;3(1):e130. doi: 10.1212/NXG.0000000000000130. eCollection 2017 Feb.

METHODS: Using exome sequencing, we identified a novel RESULTS: Perampanel therapy in CONCLUSIONS: This work demonstrates that identification of novel monogenic neurologic disorders and observation of response to targeted therapeutics can provide important insights into human nervous system functioning.

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Ahrens-Nicklas RC, Umanah GK, Sondheimer N, et al. Precision therapy for a new disorder of AMPA receptor recycling due to mutations in . Neurol Genet. 2017;3(1):e130doi: 10.1212/NXG.0000000000000130.
Ahrens-Nicklas, R. C., Umanah, G. K., Sondheimer, N., Deardorff, M. A., Wilkens, A. B., Conlin, L. K., Santani, A. B., Nesbitt, A., Juulsola, J., Ma, E., Dawson, T. M., Dawson, V. L., & Marsh, E. D. (2017). Precision therapy for a new disorder of AMPA receptor recycling due to mutations in . Neurology. Genetics, 3(1), e130. https://doi.org/10.1212/NXG.0000000000000130
Ahrens-Nicklas, Rebecca C, et al. "Precision therapy for a new disorder of AMPA receptor recycling due to mutations in ." Neurology. Genetics vol. 3,1 (2017): e130. doi: https://doi.org/10.1212/NXG.0000000000000130
Ahrens-Nicklas RC, Umanah GK, Sondheimer N, Deardorff MA, Wilkens AB, Conlin LK, Santani AB, Nesbitt A, Juulsola J, Ma E, Dawson TM, Dawson VL, Marsh ED. Precision therapy for a new disorder of AMPA receptor recycling due to mutations in . Neurol Genet. 2017 Feb 01;3(1):e130. doi: 10.1212/NXG.0000000000000130. eCollection 2017 Feb. PMID: 28180185; PMCID: PMC5289017.
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Microfluidic droplet-based PCR instrumentation for high-throughput gene expression profiling and biomarker discovery.

Biomolecular detection and quantification

Hayes CJ, Dalton TM.
PMID: 27077035
Biomol Detect Quantif. 2015 Jun 06;4:22-32. doi: 10.1016/j.bdq.2015.04.003. eCollection 2015 Jun.

PCR is a common and often indispensable technique used in medical and biological research labs for a variety of applications. Real-time quantitative PCR (RT-qPCR) has become a definitive technique for quantitating differences in gene expression levels between samples. Yet,...

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Hayes CJ, Dalton TM. Microfluidic droplet-based PCR instrumentation for high-throughput gene expression profiling and biomarker discovery. Biomol Detect Quantif. 2015;4:22-32doi: 10.1016/j.bdq.2015.04.003.
Hayes, C. J., & Dalton, T. M. (2015). Microfluidic droplet-based PCR instrumentation for high-throughput gene expression profiling and biomarker discovery. Biomolecular detection and quantification, 422-32. https://doi.org/10.1016/j.bdq.2015.04.003
Hayes, Christopher J, and Dalton, Tara M. "Microfluidic droplet-based PCR instrumentation for high-throughput gene expression profiling and biomarker discovery." Biomolecular detection and quantification vol. 4 (2015): 22-32. doi: https://doi.org/10.1016/j.bdq.2015.04.003
Hayes CJ, Dalton TM. Microfluidic droplet-based PCR instrumentation for high-throughput gene expression profiling and biomarker discovery. Biomol Detect Quantif. 2015 Jun 06;4:22-32. doi: 10.1016/j.bdq.2015.04.003. eCollection 2015 Jun. PMID: 27077035; PMCID: PMC4822205.
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Exploring the self-assembly and energy transfer of dynamic supramolecular iridium-porphyrin systems.

Dalton transactions (Cambridge, England : 2003)

Rota Martir D, Hedley GJ, Cordes DB, Slawin AM, Escudero D, Jacquemin D, Kosikova T, Philp D, Dawson DM, Ashbrook SE, Samuel ID, Zysman-Colman E.
PMID: 27722693
Dalton Trans. 2016 Nov 01;45(43):17195-17205. doi: 10.1039/c6dt02619b.

We present the first examples of dynamic supramolecular systems composed of cyclometalated Ir(iii) complexes of the form of [Ir(C^N)

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Rota Martir D, Hedley GJ, Cordes DB, et al. Exploring the self-assembly and energy transfer of dynamic supramolecular iridium-porphyrin systems. Dalton Trans. 2016;45(43):17195-17205doi: 10.1039/c6dt02619b.
Rota Martir, D., Hedley, G. J., Cordes, D. B., Slawin, A. M., Escudero, D., Jacquemin, D., Kosikova, T., Philp, D., Dawson, D. M., Ashbrook, S. E., Samuel, I. D., & Zysman-Colman, E. (2016). Exploring the self-assembly and energy transfer of dynamic supramolecular iridium-porphyrin systems. Dalton transactions (Cambridge, England : 2003), 45(43), 17195-17205. https://doi.org/10.1039/c6dt02619b
Rota Martir, Diego, et al. "Exploring the self-assembly and energy transfer of dynamic supramolecular iridium-porphyrin systems." Dalton transactions (Cambridge, England : 2003) vol. 45,43 (2016): 17195-17205. doi: https://doi.org/10.1039/c6dt02619b
Rota Martir D, Hedley GJ, Cordes DB, Slawin AM, Escudero D, Jacquemin D, Kosikova T, Philp D, Dawson DM, Ashbrook SE, Samuel ID, Zysman-Colman E. Exploring the self-assembly and energy transfer of dynamic supramolecular iridium-porphyrin systems. Dalton Trans. 2016 Nov 01;45(43):17195-17205. doi: 10.1039/c6dt02619b. PMID: 27722693.
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Differential induction of trichomes by three herbivores of black mustard.

Oecologia

Traw BM, Dawson TE.
PMID: 28547547
Oecologia. 2002 May;131(4):526-532. doi: 10.1007/s00442-002-0924-6. Epub 2002 May 01.

Specificity of plant induction responses may be important to the interactions between mustards and insect herbivores. This study compared the effects of the cabbage white butterfly, Pieris rapae (L.), cabbage looper, Trichoplusia ni (Hubner), and the mustard flea beetle,...

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Traw BM, Dawson TE. Differential induction of trichomes by three herbivores of black mustard. Oecologia. 2002;131(4):526-532doi: 10.1007/s00442-002-0924-6.
Traw, B. M., & Dawson, T. E. (2002). Differential induction of trichomes by three herbivores of black mustard. Oecologia, 131(4), 526-532. https://doi.org/10.1007/s00442-002-0924-6
Traw, Brian M, and Dawson, Todd E. "Differential induction of trichomes by three herbivores of black mustard." Oecologia vol. 131,4 (2002): 526-532. doi: https://doi.org/10.1007/s00442-002-0924-6
Traw BM, Dawson TE. Differential induction of trichomes by three herbivores of black mustard. Oecologia. 2002 May;131(4):526-532. doi: 10.1007/s00442-002-0924-6. Epub 2002 May 01. PMID: 28547547.
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Structural Requirements and Docking Analysis of Amidine-Based Sphingosine Kinase 1 Inhibitors Containing Oxadiazoles.

ACS medicinal chemistry letters

Houck JD, Dawson TK, Kennedy AJ, Kharel Y, Naimon ND, Field SD, Lynch KR, Macdonald TL.
PMID: 27190598
ACS Med Chem Lett. 2016 Mar 01;7(5):487-92. doi: 10.1021/acsmedchemlett.6b00002. eCollection 2016 May 12.

Sphingosine 1-phosphate (S1P) is a potent growth-signaling lipid that has been implicated in cancer progression, inflammation, sickle cell disease, and fibrosis. Two sphingosine kinases (SphK1 and 2) are the source of S1P; thus, inhibitors of the SphKs have potential...

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Houck JD, Dawson TK, Kennedy AJ, et al. Structural Requirements and Docking Analysis of Amidine-Based Sphingosine Kinase 1 Inhibitors Containing Oxadiazoles. ACS Med Chem Lett. 2016;7(5):487-92doi: 10.1021/acsmedchemlett.6b00002.
Houck, J. D., Dawson, T. K., Kennedy, A. J., Kharel, Y., Naimon, N. D., Field, S. D., Lynch, K. R., & Macdonald, T. L. (2016). Structural Requirements and Docking Analysis of Amidine-Based Sphingosine Kinase 1 Inhibitors Containing Oxadiazoles. ACS medicinal chemistry letters, 7(5), 487-92. https://doi.org/10.1021/acsmedchemlett.6b00002
Houck, Joseph D, et al. "Structural Requirements and Docking Analysis of Amidine-Based Sphingosine Kinase 1 Inhibitors Containing Oxadiazoles." ACS medicinal chemistry letters vol. 7,5 (2016): 487-92. doi: https://doi.org/10.1021/acsmedchemlett.6b00002
Houck JD, Dawson TK, Kennedy AJ, Kharel Y, Naimon ND, Field SD, Lynch KR, Macdonald TL. Structural Requirements and Docking Analysis of Amidine-Based Sphingosine Kinase 1 Inhibitors Containing Oxadiazoles. ACS Med Chem Lett. 2016 Mar 01;7(5):487-92. doi: 10.1021/acsmedchemlett.6b00002. eCollection 2016 May 12. PMID: 27190598; PMCID: PMC4867490.
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The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain.

Clinical epigenetics

Pangeni RP, Channathodiyil P, Huen DS, Eagles LW, Johal BK, Pasha D, Hadjistephanou N, Nevell O, Davies CL, Adewumi AI, Khanom H, Samra IS, Buzatto VC, Chandrasekaran P, Shinawi T, Dawson TP, Ashton KM, Davis C, Brodbelt AR, Jenkinson MD, Bièche I, Latif F, Darling JL, Warr TJ, Morris MR.
PMID: 26052355
Clin Epigenetics. 2015 May 27;7:57. doi: 10.1186/s13148-015-0089-x. eCollection 2015.

BACKGROUND: Tumour metastasis to the brain is a common and deadly development in certain cancers; 18-30 % of breast tumours metastasise to the brain. The contribution that gene silencing through epigenetic mechanisms plays in these metastatic tumours is not...

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Pangeni RP, Channathodiyil P, Huen DS, et al. The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain. Clin Epigenetics. 2015;7:57doi: 10.1186/s13148-015-0089-x.
Pangeni, R. P., Channathodiyil, P., Huen, D. S., Eagles, L. W., Johal, B. K., Pasha, D., Hadjistephanou, N., Nevell, O., Davies, C. L., Adewumi, A. I., Khanom, H., Samra, I. S., Buzatto, V. C., Chandrasekaran, P., Shinawi, T., Dawson, T. P., Ashton, K. M., Davis, C., Brodbelt, A. R., Jenkinson, M. D., Bièche, I., Latif, F., Darling, J. L., Warr, T. J., & Morris, M. R. (2015). The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain. Clinical epigenetics, 757. https://doi.org/10.1186/s13148-015-0089-x
Pangeni, Rajendra P, et al. "The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain." Clinical epigenetics vol. 7 (2015): 57. doi: https://doi.org/10.1186/s13148-015-0089-x
Pangeni RP, Channathodiyil P, Huen DS, Eagles LW, Johal BK, Pasha D, Hadjistephanou N, Nevell O, Davies CL, Adewumi AI, Khanom H, Samra IS, Buzatto VC, Chandrasekaran P, Shinawi T, Dawson TP, Ashton KM, Davis C, Brodbelt AR, Jenkinson MD, Bièche I, Latif F, Darling JL, Warr TJ, Morris MR. The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain. Clin Epigenetics. 2015 May 27;7:57. doi: 10.1186/s13148-015-0089-x. eCollection 2015. PMID: 26052355; PMCID: PMC4457099.
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A review of novel analytical diagnostics for liquid biopsies: spectroscopic and spectrometric serum profiling of primary and secondary brain tumors.

Brain and behavior

Spalding K, Board R, Dawson T, Jenkinson MD, Baker MJ.
PMID: 27688935
Brain Behav. 2016 Jun 29;6(9):e00502. doi: 10.1002/brb3.502. eCollection 2016 Sep.

INTRODUCTION: Spectroscopic and spectrometric analysis of biological samples is regarded as quick, cost effective, easy to operate, and spectroscopic sample preparation involves minimal sample preparation.RESULTS: Techniques like infrared (IR) spectroscopy, surface-enhanced laser desorption/ionization (SELDI)-mass spectroscopy (MS), and matrix-assisted laser...

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Spalding K, Board R, Dawson T, et al. A review of novel analytical diagnostics for liquid biopsies: spectroscopic and spectrometric serum profiling of primary and secondary brain tumors. Brain Behav. 2016;6(9):e00502doi: 10.1002/brb3.502.
Spalding, K., Board, R., Dawson, T., Jenkinson, M. D., & Baker, M. J. (2016). A review of novel analytical diagnostics for liquid biopsies: spectroscopic and spectrometric serum profiling of primary and secondary brain tumors. Brain and behavior, 6(9), e00502. https://doi.org/10.1002/brb3.502
Spalding, Katie, et al. "A review of novel analytical diagnostics for liquid biopsies: spectroscopic and spectrometric serum profiling of primary and secondary brain tumors." Brain and behavior vol. 6,9 (2016): e00502. doi: https://doi.org/10.1002/brb3.502
Spalding K, Board R, Dawson T, Jenkinson MD, Baker MJ. A review of novel analytical diagnostics for liquid biopsies: spectroscopic and spectrometric serum profiling of primary and secondary brain tumors. Brain Behav. 2016 Jun 29;6(9):e00502. doi: 10.1002/brb3.502. eCollection 2016 Sep. PMID: 27688935; PMCID: PMC5036428.
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INBREEDING DEPRESSION IN MORPHOLOGICAL AND PHYSIOLOGICAL TRAITS OF SCHIEDEA LYDGATEI (CARYOPHYLLACEAE) IN TWO ENVIRONMENTS.

Evolution; international journal of organic evolution

Norman JK, Sarai AK, Weller SG, Dawson TE.
PMID: 28565008
Evolution. 1995 Apr;49(2):297-306. doi: 10.1111/j.1558-5646.1995.tb02242.x.

We compared inbreeding depression in hermaphroditic Schiedea lydgatei and its gynodioecious sister species, S. salicaria, to infer the level of inbreeding depression in their common ancestor. With measurements of selfing rates, this information can be used to assess the...

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Norman JK, Sarai AK, Weller SG, et al. INBREEDING DEPRESSION IN MORPHOLOGICAL AND PHYSIOLOGICAL TRAITS OF SCHIEDEA LYDGATEI (CARYOPHYLLACEAE) IN TWO ENVIRONMENTS. Evolution. 1995;49(2):297-306doi: 10.1111/j.1558-5646.1995.tb02242.x.
Norman, J. K., Sarai, A. K., Weller, S. G., & Dawson, T. E. (1995). INBREEDING DEPRESSION IN MORPHOLOGICAL AND PHYSIOLOGICAL TRAITS OF SCHIEDEA LYDGATEI (CARYOPHYLLACEAE) IN TWO ENVIRONMENTS. Evolution; international journal of organic evolution, 49(2), 297-306. https://doi.org/10.1111/j.1558-5646.1995.tb02242.x
Norman, Joanna K, et al. "INBREEDING DEPRESSION IN MORPHOLOGICAL AND PHYSIOLOGICAL TRAITS OF SCHIEDEA LYDGATEI (CARYOPHYLLACEAE) IN TWO ENVIRONMENTS." Evolution; international journal of organic evolution vol. 49,2 (1995): 297-306. doi: https://doi.org/10.1111/j.1558-5646.1995.tb02242.x
Norman JK, Sarai AK, Weller SG, Dawson TE. INBREEDING DEPRESSION IN MORPHOLOGICAL AND PHYSIOLOGICAL TRAITS OF SCHIEDEA LYDGATEI (CARYOPHYLLACEAE) IN TWO ENVIRONMENTS. Evolution. 1995 Apr;49(2):297-306. doi: 10.1111/j.1558-5646.1995.tb02242.x. PMID: 28565008.
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Seasonal water uptake and movement in root systems of Australian phraeatophytic plants of dimorphic root morphology: a stable isotope investigation.

Oecologia

Dawson TE, Pate JS.
PMID: 28307187
Oecologia. 1996 Mar;107(1):13-20. doi: 10.1007/BF00582230.

A natural abundance hydrogen stable isotope technique was used to study seasonal changes in source water utilization and water movement in the xylem of dimorphic root systems and stem bases of several woody shrubs or trees in mediterranean-type ecosystems...

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Dawson TE, Pate JS. Seasonal water uptake and movement in root systems of Australian phraeatophytic plants of dimorphic root morphology: a stable isotope investigation. Oecologia. 1996;107(1):13-20doi: 10.1007/BF00582230.
Dawson, T. E., & Pate, J. S. (1996). Seasonal water uptake and movement in root systems of Australian phraeatophytic plants of dimorphic root morphology: a stable isotope investigation. Oecologia, 107(1), 13-20. https://doi.org/10.1007/BF00582230
Dawson, Todd E, and Pate, John S. "Seasonal water uptake and movement in root systems of Australian phraeatophytic plants of dimorphic root morphology: a stable isotope investigation." Oecologia vol. 107,1 (1996): 13-20. doi: https://doi.org/10.1007/BF00582230
Dawson TE, Pate JS. Seasonal water uptake and movement in root systems of Australian phraeatophytic plants of dimorphic root morphology: a stable isotope investigation. Oecologia. 1996 Mar;107(1):13-20. doi: 10.1007/BF00582230. PMID: 28307187.
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Practical scheme for quantum computation with any two-qubit entangling gate.

Physical review letters

Bremner MJ, Dawson CM, Dodd JL, Gilchrist A, Harrow AW, Mortimer D, Nielsen MA, Osborne TJ.
PMID: 12484981
Phys Rev Lett. 2002 Dec 09;89(24):247902. doi: 10.1103/PhysRevLett.89.247902. Epub 2002 Nov 25.

Which gates are universal for quantum computation? Although it is well known that certain gates on two-level quantum systems (qubits), such as the controlled-not, are universal when assisted by arbitrary one-qubit gates, it has only recently become clear precisely...

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Bremner MJ, Dawson CM, Dodd JL, et al. Practical scheme for quantum computation with any two-qubit entangling gate. Phys Rev Lett. 2002;89(24):247902doi: 10.1103/PhysRevLett.89.247902.
Bremner, M. J., Dawson, C. M., Dodd, J. L., Gilchrist, A., Harrow, A. W., Mortimer, D., Nielsen, M. A., & Osborne, T. J. (2002). Practical scheme for quantum computation with any two-qubit entangling gate. Physical review letters, 89(24), 247902. https://doi.org/10.1103/PhysRevLett.89.247902
Bremner, Michael J, et al. "Practical scheme for quantum computation with any two-qubit entangling gate." Physical review letters vol. 89,24 (2002): 247902. doi: https://doi.org/10.1103/PhysRevLett.89.247902
Bremner MJ, Dawson CM, Dodd JL, Gilchrist A, Harrow AW, Mortimer D, Nielsen MA, Osborne TJ. Practical scheme for quantum computation with any two-qubit entangling gate. Phys Rev Lett. 2002 Dec 09;89(24):247902. doi: 10.1103/PhysRevLett.89.247902. Epub 2002 Nov 25. PMID: 12484981.
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The training of pupil nurses.

Nursing times

DAWSON IM.
PMID: 13720321
Nurs Times. 1961 Apr 14;57:474-6.

No abstract available.

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DAWSON IM. The training of pupil nurses. Nurs Times. 1961;57:474-6
DAWSON, I. M. (1961). The training of pupil nurses. Nursing times, 57474-6.
DAWSON, I M. "The training of pupil nurses." Nursing times vol. 57 (1961): 474-6.
DAWSON IM. The training of pupil nurses. Nurs Times. 1961 Apr 14;57:474-6. PMID: 13720321.
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A Biography of François Magendie.

Medical library and historical journal

Dawson PM.
PMID: 18340932
Med Library Hist J. 1906 Dec;4(4):364-77.

No abstract available.

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Dawson PM. A Biography of François Magendie. Med Library Hist J. 1906;4(4):364-77
Dawson, P. M. (1906). A Biography of François Magendie. Medical library and historical journal, 4(4), 364-77.
Dawson, P M. "A Biography of François Magendie." Medical library and historical journal vol. 4,4 (1906): 364-77.
Dawson PM. A Biography of François Magendie. Med Library Hist J. 1906 Dec;4(4):364-77. PMID: 18340932; PMCID: PMC1692507.
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Showing 1 to 12 of 397 entries