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Showing 1 to 12 of 37 entries
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Metabolism of human erythrocyte glucose-6-phosphate dehydrogenase. III - isolation of a protein involved in the 6-phosphogluconate-induced inactivation.

FEBS letters

Bonsignore A, De Flora A, Lorenzoni I, Mangiarotti MA, Cancedda R, Dina D.
PMID: 11945287
FEBS Lett. 1968 Aug;1(3):176-178. doi: 10.1016/0014-5793(68)80053-5.

No abstract available.

Early and late effects of aspirin and naproxen on microRNAs in the lung and blood of mice, either unexposed or exposed to cigarette smoke.

Oncotarget

Izzotti A, Balansky R, Ganchev G, Iltcheva M, Longobardi M, Pulliero A, Camoirano A, D'Agostini F, Geretto M, Micale RT, La Maestra S, Miller MS, Steele VE, De Flora S.
PMID: 29156752
Oncotarget. 2017 Aug 24;8(49):85716-85748. doi: 10.18632/oncotarget.20464. eCollection 2017 Oct 17.

We recently showed that nonsteroidal anti-inflammatory drugs (NSAIDs) are able to inhibit the lung tumors induced by cigarette smoke, either mainstream (MCS) or environmental (ECS), in female mice. We used subsets of mice to analyze the expression of 1135...

Three-dimensional mapping of neurofibrillary tangle burden in the human medial temporal lobe.

Brain : a journal of neurology

Yushkevich PA, Muñoz López M, Iñiguez de Onzoño Martin MM, Ittyerah R, Lim S, Ravikumar S, Bedard ML, Pickup S, Liu W, Wang J, Hung LY, Lasserve J, Vergnet N, Xie L, Dong M, Cui S, McCollum L, Robinson JL, Schuck T, de Flores R, Grossman M, Tisdall MD, Prabhakaran K, Mizsei G, Das SR, Artacho-Pérula E, Arroyo Jiménez MDM, Marcos Raba MP, Molina Romero FJ, Cebada Sánchez S, Delgado González JC, de la Rosa-Prieto C, Córcoles Parada M, Lee EB, Trojanowski JQ, Ohm DT, Wisse LEM, Wolk DA, Irwin DJ, Insausti R.
PMID: 34259858
Brain. 2021 Oct 22;144(9):2784-2797. doi: 10.1093/brain/awab262.

Tau protein neurofibrillary tangles are closely linked to neuronal/synaptic loss and cognitive decline in Alzheimer's disease and related dementias. Our knowledge of the pattern of neurofibrillary tangle progression in the human brain, critical to the development of imaging biomarkers...

Hippocampal subfield volumetry from structural isotropic 1 mm.

Human brain mapping

Wisse LEM, Chételat G, Daugherty AM, de Flores R, la Joie R, Mueller SG, Stark CEL, Wang L, Yushkevich PA, Berron D, Raz N, Bakker A, Olsen RK, Carr VA.
PMID: 33058385
Hum Brain Mapp. 2021 Feb 01;42(2):539-550. doi: 10.1002/hbm.25234. Epub 2020 Oct 15.

Spurred by availability of automatic segmentation software, in vivo MRI investigations of human hippocampal subfield volumes have proliferated in the recent years. However, a majority of these studies apply automatic segmentation to MRI scans with approximately 1 × 1...

Growth and decline of the COVID-19 epidemic wave in Italy from March to June 2020.

Journal of medical virology

De Flora S, La Maestra S.
PMID: 32902903
J Med Virol. 2021 Mar;93(3):1613-1619. doi: 10.1002/jmv.26499. Epub 2020 Sep 30.

March 21, 2020 was the ridgeline between the growth of the coronavirus disease 2019 (COVID-19) epidemic wave in Italy and the start of its decline. We analyzed the epidemic patterns from March 1 to June 30. There was a...

Neuropsychology and neuroimaging profiles of amyloid-positive versus amyloid-negative amnestic mild cognitive impairment patients.

Alzheimer's & dementia (Amsterdam, Netherlands)

Tomadesso C, de La Sayette V, de Flores R, Bourgeat P, Villemagne VL, Egret S, Eustache F, Chételat G.
PMID: 29780872
Alzheimers Dement (Amst). 2018 Mar 17;10:269-277. doi: 10.1016/j.dadm.2018.02.008. eCollection 2018.

INTRODUCTION: Patients with amnestic mild cognitive impairment (aMCI) are heterogeneous as regard to their amyloid status. The present study aimed at highlighting the neuropsychological, brain atrophy, and hypometabolism profiles of amyloid-positive (Aβpos) versus amyloid-negative (Aβneg) aMCI patients.METHODS: Forty-four aMCI...

Functional homogenization of flower visitor communities with urbanization.

Ecology and evolution

Deguines N, Julliard R, de Flores M, Fontaine C.
PMID: 27066219
Ecol Evol. 2016 Feb 24;6(7):1967-76. doi: 10.1002/ece3.2009. eCollection 2016 Apr.

Land-use intensification and resulting habitat loss are put forward as the main causes of flower visitor decline. However, the impact of urbanization, the prime driver of land-use intensification in Europe, is poorly studied. In particular, our understanding of whether...

Longitudinal atrophy in early Braak regions in preclinical Alzheimer's disease.

Human brain mapping

Xie L, Wisse LEM, Das SR, Vergnet N, Dong M, Ittyerah R, de Flores R, Yushkevich PA, Wolk DA.
PMID: 32845545
Hum Brain Mapp. 2020 Nov;41(16):4704-4717. doi: 10.1002/hbm.25151. Epub 2020 Aug 26.

A major focus of Alzheimer's disease (AD) research has been finding sensitive outcome measures to disease progression in preclinical AD, as intervention studies begin to target this population. We hypothesize that tailored measures of longitudinal change of the medial...

Progress update from the hippocampal subfields group.

Alzheimer's & dementia (Amsterdam, Netherlands)

Olsen RK, Carr VA, Daugherty AM, La Joie R, Amaral RSC, Amunts K, Augustinack JC, Bakker A, Bender AR, Berron D, Boccardi M, Bocchetta M, Burggren AC, Chakravarty MM, Chételat G, de Flores R, DeKraker J, Ding SL, Geerlings MI, Huang Y, Insausti R, Johnson EG, Kanel P, Kedo O, Kennedy KM, Keresztes A, Lee JK, Lindenberger U, Mueller SG, Mulligan EM, Ofen N, Palombo DJ, Pasquini L, Pluta J, Raz N, Rodrigue KM, Schlichting ML, Lee Shing Y, Stark CEL, Steve TA, Suthana NA, Wang L, Werkle-Bergner M, Yushkevich PA, Yu Q, Wisse LEM.
PMID: 31245529
Alzheimers Dement (Amst). 2019 Jun 13;11:439-449. doi: 10.1016/j.dadm.2019.04.001. eCollection 2019 Dec.

INTRODUCTION: Heterogeneity of segmentation protocols for medial temporal lobe regions and hippocampal subfields on METHODS: Our international working group, funded by the EU Joint Programme-Neurodegenerative Disease Research (JPND), is working toward the production of a reliable, validated, harmonized protocol...

Conserved role of the urotensin II receptor 4 signalling pathway to control body straightness in a tetrapod.

Open biology

Alejevski F, Leemans M, Gaillard AL, Leistenschneider D, de Flori C, Bougerol M, Le Mével S, Herrel A, Fini JB, Pézeron G, Tostivint H.
PMID: 34375549
Open Biol. 2021 Aug;11(8):210065. doi: 10.1098/rsob.210065. Epub 2021 Aug 11.

Urp1 and Urp2 are two neuropeptides of the urotensin II family identified in teleost fish and mainly expressed in cerebrospinal fluid (CSF)-contacting neurons. It has been recently proposed that Urp1 and Urp2 are required for correct axis formation and...

Discordance of PIK3CA and TP53 mutations between breast cancer brain metastases and matched primary tumors.

Scientific reports

Thulin A, Andersson C, Werner Rönnerman E, De Lara S, Chamalidou C, Schoenfeld A, Kovács A, Fagman H, Enlund F, Linderholm BK.
PMID: 34876602
Sci Rep. 2021 Dec 07;11(1):23548. doi: 10.1038/s41598-021-02903-x.

There is limited knowledge of the biology of breast cancer (BC) brain metastasis (BM). We primarily aimed to determine the mutations in BCBM and to compare the mutational pattern with the matched primary breast cancer (BC). Secondary aims were...

Tau pathology mediates age effects on medial temporal lobe structure.

Neurobiology of aging

Wisse LE, Xie L, Das SR, de Flores R, Hansson O, Habes M, Doshi J, Davatzikos C, Yushkevich PA, Wolk DA.
PMID: 34740075
Neurobiol Aging. 2022 Jan;109:135-144. doi: 10.1016/j.neurobiolaging.2021.09.017. Epub 2021 Sep 24.

Hippocampal atrophy is endemic in 'normal aging' but it is unclear what factors drive age-related changes in medial temporal lobe (MTL) structural measures. We investigated cross-sectional (n = 191) and longitudinal (n = 164) MTL atrophy patterns in cognitively...

Showing 1 to 12 of 37 entries