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Showing 1 to 12 of 25 entries
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Isometric Stretch Alters Vascular Reactivity of Mouse Aortic Segments.

Frontiers in physiology

De Moudt S, Leloup A, Van Hove C, De Meyer G, Fransen P.
PMID: 28360864
Front Physiol. 2017 Mar 16;8:157. doi: 10.3389/fphys.2017.00157. eCollection 2017.

Most vaso-reactive studies in mouse aortic segments are performed in isometric conditions and at an optimal preload, which is the preload corresponding to a maximal contraction by non-receptor or receptor-mediated stimulation. In general, this optimal preload ranges from about...

Transcript abundance on its own cannot be used to infer fluxes in central metabolism.

Frontiers in plant science

Schwender J, König C, Klapperstück M, Heinzel N, Munz E, Hebbelmann I, Hay JO, Denolf P, De Bodt S, Redestig H, Caestecker E, Jakob PM, Borisjuk L, Rolletschek H.
PMID: 25506350
Front Plant Sci. 2014 Nov 28;5:668. doi: 10.3389/fpls.2014.00668. eCollection 2014.

An attempt has been made to define the extent to which metabolic flux in central plant metabolism is reflected by changes in the transcriptome and metabolome, based on an analysis of in vitro cultured immature embryos of two oilseed...

Ultra-low-angle microtomy and static secondary ion mass spectrometry for molecular depth profiling of UV-curable acrylate multilayers at the nanoscale.

Analytical and bioanalytical chemistry

Vercammen Y, De Mondt R, Van Luppen J, Vangaever F, Van Vaeck L.
PMID: 20213176
Anal Bioanal Chem. 2010 Apr;396(8):2943-54. doi: 10.1007/s00216-010-3507-0. Epub 2010 Mar 06.

Development of sustainable materials requires methods capable of probing the molecular composition of samples not only at the surface but also in depth. Static secondary ion mass spectrometry (S-SIMS) characterises the distribution of organic and inorganic compounds at the...

Age-related cognitive decline in spatial learning and memory of C57BL/6J mice.

Behavioural brain research

Hendrickx JO, De Moudt S, Calus E, De Deyn PP, Van Dam D, De Meyer GRY.
PMID: 34728276
Behav Brain Res. 2022 Feb 10;418:113649. doi: 10.1016/j.bbr.2021.113649. Epub 2021 Oct 30.

During the last decades, most of the preclinical neurodegenerative research was performed in mouse models of amyloidosis, tauopathies or α-synucleinopathies preferentially maintained on a C57BL/6J background. However, comprehensive neurobehavioural data from C57BL/6J mice outlining the critical point of spontaneous...

Endothelial Contribution to Warfarin-Induced Arterial Media Calcification in Mice.

International journal of molecular sciences

Van den Bergh G, De Moudt S, Van den Branden A, Neven E, Leysen H, Maudsley S, De Meyer GRY, D'Haese P, Verhulst A.
PMID: 34769044
Int J Mol Sci. 2021 Oct 27;22(21). doi: 10.3390/ijms222111615.

Arterial media calcification (AMC) is predominantly regulated by vascular smooth muscle cells (VSMCs), which transdifferentiate into pro-calcifying cells. In contrast, there is little evidence for endothelial cells playing a role in the disease. The current study investigates cellular functioning...

Long-Term Pharmacological Inhibition of the Activity of All NOS Isoforms Rather Than Genetic Knock-Out of Endothelial NOS Leads to Impaired Spatial Learning and Memory in C57BL/6 Mice.

Biomedicines

Hendrickx JO, De Moudt S, Calus E, De Deyn PP, Van Dam D, De Meyer GRY.
PMID: 34944725
Biomedicines. 2021 Dec 14;9(12). doi: 10.3390/biomedicines9121905.

Increasing epidemiological and experimental evidence points to a link between arterial stiffness and rapid cognitive decline. However, the underlying mechanism linking the two diseases is still unknown. The importance of nitric oxide synthases in both diseases is well-defined. In...

GSK-7975A, an inhibitor of Ca.

European journal of pharmacology

De Moudt S, De Munck D, Coornaert I, Fransen P.
PMID: 34052216
Eur J Pharmacol. 2021 Sep 05;906:174197. doi: 10.1016/j.ejphar.2021.174197. Epub 2021 May 27.

GSK-7975A is described to inhibit stromal interaction molecule 1(STIM1)-mediated Ca

Genome duplication and the origin of angiosperms.

Trends in ecology & evolution

De Bodt S, Maere S, Van de Peer Y.
PMID: 16701441
Trends Ecol Evol. 2005 Nov;20(11):591-7. doi: 10.1016/j.tree.2005.07.008. Epub 2005 Aug 09.

Despite intensive research, little is known about the origin of the angiosperms and their rise to ecological dominance during the Early Cretaceous. Based on whole-genome analyses of Arabidopsis thaliana, there is compelling evidence that angiosperms underwent two whole-genome duplication...

Thermostability of soluble and immobilized alpha-amylase from Bacillus licheniformis.

Biotechnology and bioengineering

De Cordt S, Vanhoof K, Hu J, Maesmans G, Hendrickx M, Tobback P.
PMID: 18601130
Biotechnol Bioeng. 1992 Jul;40(3):396-402. doi: 10.1002/bit.260400309.

In view of a possible application of the alpha-amylase from Bacillus licheniformis as a time-temperature integrator for evaluation of heat processes,(11) thermal inactivation kinetics of the dissolved and covalently immobilized enzyme were studied in the temperature range 90-108 degrees...

Feasibility of static secondary ion mass spectrometry to study physicochemical interactions between organic components and silver in thermographic systems.

Rapid communications in mass spectrometry : RCM

De Mondt R, Van Vaeck L, Lenaerts J, Geuens I, Van Luppen J.
PMID: 16444686
Rapid Commun Mass Spectrom. 2006;20(4):641-52. doi: 10.1002/rcm.2357.

Chemical engineering of high-technology products requires elucidation of intermolecular interactions in complex materials. As part of an extensive study on thermographic systems, static secondary ion mass spectrometry (S-SIMS) was used to probe the physicochemical behaviour of active compounds, such...

Theoretical Consideration on the Influence of the z-Value of a Single Component Time/Temperature Integrator on Thermal Process Impact Evaluation.

Journal of food protection

VAN Loey A, Ludikhuyze L, Hendrickx M, DE Cordt S, Tobback P.
PMID: 31121789
J Food Prot. 1995 Jan;58(1):39-48. doi: 10.4315/0362-028X-58.1.39.

The allowed difference in z-value between a single component time/temperature integrator (SCTTI) and target attribute to measure the impact of a thermal process with a given accuracy was examined theoretically. For isothermal heating profiles, the issue and the degree...

Long-Term Pharmacological Inhibition of the Activity of All NOS Isoforms Rather Than Genetic Knock-Out of Endothelial NOS Leads to Impaired Spatial Learning and Memory in C57BL/6 Mice.

Biomedicines

Hendrickx JO, De Moudt S, Calus E, De Deyn PP, Van Dam D, De Meyer GRY.
PMID: 34944725
Biomedicines. 2021 Dec 14;9(12). doi: 10.3390/biomedicines9121905.

Increasing epidemiological and experimental evidence points to a link between arterial stiffness and rapid cognitive decline. However, the underlying mechanism linking the two diseases is still unknown. The importance of nitric oxide synthases in both diseases is well-defined. In...

Showing 1 to 12 of 25 entries