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Showing 1 to 12 of 43 entries
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Some molecular and clinical aspects of genetic predisposition to malignant melanoma and tumours of various site of origin.

Hereditary cancer in clinical practice

Debniak T.
PMID: 19725989
Hered Cancer Clin Pract. 2007 Jun 15;5(2):97-116. doi: 10.1186/1897-4287-5-2-97.

Based on epidemiological data we can assume that at least some malignant melanoma (MM) and breast cancer cases can be caused by the same genetic factors. CDKN2A, which encodes the p16 protein, a cyclin-dependent kinase inhibitor suppressing cell proliferation,...

Population screening for cancer family syndromes in the west pomeranian region of poland.

Hereditary cancer in clinical practice

Gronwald J, Raczyński A, Tarhoni M, Blachowski M, Huzarski T, Byrski T, Tołoczko-Grabarek A, Debniak T, Cybulski C, Huzarska J, Oszurek O, Lubiński J.
PMID: 20223006
Hered Cancer Clin Pract. 2006 Jan 15;4(1):56. doi: 10.1186/1897-4287-4-1-56.

No abstract available.

The 3020insC Allele of NOD2 Predisposes to Cancers of Multiple Organs.

Hereditary cancer in clinical practice

Lubiński J, Huzarski T, Kurzawski G, Suchy J, Masojć B, Mierzejewski M, Lener M, Domagała W, Chosia M, Teodorczyk U, Medrek K, Debniak T, Złowocka E, Gronwald J, Byrski T, Grabowska E, Nej K, Szymańska A, Szymańska J, Matyjasik J, Cybulski C, Jakubowska A, Górski B, Narod SA.
PMID: 20223031
Hered Cancer Clin Pract. 2005 Mar 15;3(2):59-63. doi: 10.1186/1897-4287-3-2-59.

The NOD2 gene has been associated with susceptibility to Crohn's disease and individuals with Crohn's disease are at increased risk for cancer at a number of organ sites. We studied the association between the 3020insC allele of the NOD2...

Methodology and evaluation of the renal arterial system.

Central European journal of urology

Drewniak T, Rzepecki M, Juszczak K, Moczulski Z, Reczyńska K, Jakubowska M.
PMID: 24579016
Cent European J Urol. 2013;66(2):152-7. doi: 10.5173/ceju.2013.02.art10. Epub 2013 Aug 13.

INTRODUCTION: The broad range of medical images and image processing technologies are applied in urology. The aim was to propose methodology to assess three-dimensional (3D) arrangement of renal arterial tree and to build a statistical model for analyzing the...

Highly regioselective opening of zirconacyclopentadienes by remote coordination: concise synthesis of the furan core of the leupyrrins.

Chemical communications (Cambridge, England)

Debnar T, Dreisigacker S, Menche D.
PMID: 23230573
Chem Commun (Camb). 2013 Jan 25;49(7):725-7. doi: 10.1039/c2cc37678d.

An efficient protocol for the highly regioselective opening of aliphatic zirconacyclopentadienes is reported. The one-pot process involves a zirconocene-mediated cyclization of 1,6-diynes and highly selective cleavage of the metallacycles with NBS and enables a concise synthesis of the tetrahydrofuran-core...

Cancers

Suszynska M, Kluzniak W, Wokolorczyk D, Jakubowska A, Huzarski T, Gronwald J, Debniak T, Szwiec M, Ratajska M, Klonowska K, Narod S, Bogdanova N, Dörk T, Lubinski J, Cybulski C, Kozlowski P.
PMID: 31142030
Cancers (Basel). 2019 May 28;11(6). doi: 10.3390/cancers11060740.

In addition to several well-established breast cancer (BC) susceptibility genes, the contribution of other candidate genes to BC risk remains mostly undefined.

The Effect of Adhesive Additives on Silica Gel Water Sorption Properties.

Entropy (Basel, Switzerland)

Sztekler K, Kalawa W, Mlonka-Medrala A, Nowak W, Mika Ł, Krzywanski J, Grabowska K, Sosnowski M, Debniak M.
PMID: 33286102
Entropy (Basel). 2020 Mar 12;22(3). doi: 10.3390/e22030327.

Adsorption chillers are characterized by low electricity consumption, lack of moving parts, and high reliability. The disadvantage of these chillers is their large weight due to low adsorbent sorption capacity. Therefore, the attention is turned to finding a sorbent...

Polymorphisms in .

Hereditary cancer in clinical practice

Białkowska K, Marciniak W, Muszyńska M, Baszuk P, Gupta S, Jaworska-Bieniek K, Sukiennicki G, Durda K, Gromowski T, Lener M, Prajzendanc K, Łukomska A, Cybulski C, Huzarski T, Gronwald J, Dębniak T, Lubiński J, Jakubowska A.
PMID: 32765800
Hered Cancer Clin Pract. 2020 Jul 31;18:16. doi: 10.1186/s13053-020-00147-w. eCollection 2020.

BACKGROUND: Matrix metalloproteinases (MMPs) and metallothioneins (MTs) are Zinc-related proteins which are involved in processes crucial for carcinogenesis such as angiogenesis, proliferation and apoptosis. Several single nucleotide polymorphisms (SNPs) in MMPs and MTs that affect genes expression have been...

Psoriasis vulgaris and familial cancer risk- a population-based study.

Hereditary cancer in clinical practice

Maleszka R, Paszkowska-Szczur K, Soczawa E, Boer M, Różewicka-Czabańska M, Wiśniewska J, Mirecka A, Krysztoforska L, Adamski Z, Lubinski J, Dębniak T.
PMID: 23805825
Hered Cancer Clin Pract. 2013 Jun 28;11(1):6. doi: 10.1186/1897-4287-11-6.

BACKGROUND: Follow-up studies of psoriasis patients indicate an increased risk in the occurrence of malignancies at different sites of origin. Population stratification and/or complicated interpretation of evidence on the risk of cancer (due to the small number of patients...

Age at diagnosis of cancer as predictor of mutation occurrence in families suspected of HNPCC.

Journal of applied genetics

Kurzawski G, Debniak T, Kladny J, Lubiński J.
PMID: 14564042
J Appl Genet. 2001;42(3):359-66.

Analysis of significance of age at cancer diagnosis as a factor allowing identification of a subgroup of patients with a high frequency of hMSH2 and hMLH1 mutations among families that fulfil suspected HNPCC criteria was performed. DNA from thirty-one...

Low-risk Genes and Multi-organ Cancer Risk in the Polish Population.

Hereditary cancer in clinical practice

Debniak T, Cybulski C, Kurzawski G, Górski B, Huzarski T, Byrski T, Gronwald J, Suchy J, Masojć B, Mierzejewski M, Lener M, Teodorczyk U, Medrek K, Złowocka E, Grabowska-Kłujszo E, Nej-Wołosiak K, Szymańska A, Szymańska-Pasternak J, Matyjasik J, Wetering Tv, Jakubowska A, Oszurek O, Tołoczko-Grabarek A, Castaneda J, Scott R, Narod SA, Lubiński J.
PMID: 20223005
Hered Cancer Clin Pract. 2006 Jan 15;4(1):52-5. doi: 10.1186/1897-4287-4-1-52.

No abstract available.

Management of ovarian and endometrial cancers in women belonging to HNPCC carrier families: review of the literature and results of cancer risk assessment in Polish HNPCC families.

Hereditary cancer in clinical practice

Dębniak T, Gromowski T, Scott RJ, Gronwald J, Huzarski T, Byrski T, Kurzawski G, Dymerska D, Górski B, Paszkowska-Szczur K, Cybulski C, Serrano-Fernandez P, Lubiński J.
PMID: 25606063
Hered Cancer Clin Pract. 2015 Jan 16;13(1):3. doi: 10.1186/s13053-015-0025-2. eCollection 2015.

BACKGROUND: Over half the cancer deaths in HNPCC families are due to extra-colonic malignancies that include endometrial and ovarian cancers. The benefits of surveillance for gynecological cancers are not yet proven and there is no consensus on the optimal...

Showing 1 to 12 of 43 entries