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Showing 1 to 12 of 685 entries
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Metal-free nitroxyl radical-mediated β-C(sp.

Chemical communications (Cambridge, England)

Qian P, Deng Y, Mei H, Han J, Pan Y.
PMID: 28229143
Chem Commun (Camb). 2017 Mar 07;53(20):2958-2961. doi: 10.1039/c7cc00145b.

The first metal-free nitroxyl-radical-mediated β-amination of saturated ketones by using heteroaryl halides as amide precursors has been developed. This reaction proceeds through a cascade α-aminoxylation/Cope-like elimination/aza-Michael addition sequence to afford β-amino ketone derivatives with excellent yields. TEMPO plays multiple...

Role of interleukin-1 and its antagonism of hepatic stellate cell proliferation and liver fibrosis in the Abcb4(-/-) mouse model.

World journal of hepatology

Reiter FP, Wimmer R, Wottke L, Artmann R, Nagel JM, Carranza MO, Mayr D, Rust C, Fickert P, Trauner M, Gerbes AL, Hohenester S, Denk GU.
PMID: 27004088
World J Hepatol. 2016 Mar 18;8(8):401-10. doi: 10.4254/wjh.v8.i8.401.

AIM: To study the interleukin-1 (IL-1) pathway as a therapeutic target for liver fibrosis in vitro and in vivo using the ATP-binding cassette transporter b4(-/-) (Abcb4(-/-)) mouse model.METHODS: Female and male Abcb4(-/-) mice from 6 to 13 mo of...

O-Acyl oximes: versatile building blocks for N-heterocycle formation in recent transition metal catalysis.

Organic & biomolecular chemistry

Huang H, Cai J, Deng GJ.
PMID: 26727109
Org Biomol Chem. 2016 Feb 07;14(5):1519-30. doi: 10.1039/c5ob02417j.

O-Acyl oximes are versatile building blocks being widely applied in organic synthesis, especially for N-heterocycle construction under transition metal catalysis. In the last decade, aza-Heck cyclization using oximes has been progressing in the preparation of functionalized pyrrolines, and instead...

Fluorescent dendritic organogels based on 2-(2'-hydroxyphenyl)benzoxazole: emission enhancement and multiple stimuli-responsive properties.

Chemistry (Weinheim an der Bergstrasse, Germany)

Chen H, Feng Y, Deng GJ, Liu ZX, He YM, Fan QH.
PMID: 26095320
Chemistry. 2015 Jul 27;21(31):11018-28. doi: 10.1002/chem.201500849. Epub 2015 Jun 19.

A new highly efficient and versatile poly(benzyl ether) dendritic organogelator HPB-G1 with 2-(2'-hydroxyphenyl)benzoxazole (HPB) at the focal point has been designed and synthesized. HPB-G1 can form stable organogels toward various apolar and polar organic solvents. Further studies revealed that...

Metabolic effects of a mitochondrial-targeted coenzyme Q analog in high fat fed obese mice.

Pharmacology research & perspectives

Fink BD, Guo DF, Kulkarni CA, Rahmouni K, Kerns RJ, Sivitz WI.
PMID: 28357127
Pharmacol Res Perspect. 2017 Mar 10;5(2):e00301. doi: 10.1002/prp2.301. eCollection 2017 Apr.

We recently reported that mitoquinone (mitoQ, 500 

Analgesic activity of cynaropicrinon on post-inflammatory irritable bowel syndrome visceral hypersensitivity in a rat model.

Experimental and therapeutic medicine

Shi H, Zhu X, Cui Y, Qin Y, Yang L, Deng X.
PMID: 29067122
Exp Ther Med. 2017 Nov;14(5):4476-4482. doi: 10.3892/etm.2017.5037. Epub 2017 Aug 25.

Visceral hypersensitivity is one of the most common symptoms in patients with post-inflammatory-irritable bowel syndrome (PI-IBS). Enterochromaffin (EC) cells and 5-hydroxytryptamine (5-HT) are important in the development of visceral hyperalgesia, and EC cells are influenced by helper T-cell subtype...

Targeted Synthesis of Unique Nickel Sulfide (NiS, NiS.

ACS applied materials & interfaces

Luo P, Zhang H, Liu L, Zhang Y, Deng J, Xu C, Hu N, Wang Y.
PMID: 27996237
ACS Appl Mater Interfaces. 2017 Jan 25;9(3):2500-2508. doi: 10.1021/acsami.6b13984. Epub 2017 Jan 09.

Water splitting is one of the ideal technologies to meet the ever increasing demands of energy. Many materials have aroused great attention in this field. The family of nickel-based sulfides is one of the examples that possesses interesting properties...

Electrotunable artificial molecules based on van der Waals heterostructures.

Science advances

Zhang ZZ, Song XX, Luo G, Deng GW, Mosallanejad V, Taniguchi T, Watanabe K, Li HO, Cao G, Guo GC, Nori F, Guo GP.
PMID: 29062893
Sci Adv. 2017 Oct 20;3(10):e1701699. doi: 10.1126/sciadv.1701699. eCollection 2017 Oct.

Quantum confinement has made it possible to detect and manipulate single-electron charge and spin states. The recent focus on two-dimensional (2D) materials has attracted significant interests on possible applications to quantum devices, including detecting and manipulating either single-electron charging...

Clinical comparative study on Nitrous Oxide inhalation versus intravenous propofol and Midazolam sedation in Transnasal Gastroscopy.

Pakistan journal of medical sciences

Xiaoqian Z, Tao Z, Bingsong L, Jing L, Yu D, Weilan Z.
PMID: 29067060
Pak J Med Sci. 2017 Jul-Aug;33(4):891-894. doi: 10.12669/pjms.334.12290.

OBJECTIVE: To investigate the Clinical practice value of nitrous oxide inhalation and intravenous propofol and midazolam sedation in transnasal gastroscopy.METHOD: From December 2012 to April 2014, two hundred patients receiving painless transnasal gastroscopy on a voluntary basis were selected...

A novel high power X-band ferrite phase shifter.

The Review of scientific instruments

Deng GJ, Huang WH, Li JW, Ba T, Guo LT, Jiang Y.
PMID: 28147666
Rev Sci Instrum. 2017 Jan;88(1):014705. doi: 10.1063/1.4974105.

A novel high power X-band ferrite phase shifter (PS) employing the structure of several waveguides connected in parallel is proposed. Each of the waveguides is a phase shift unit utilizing a dual-toroid structure. First, the phase shift unit is...

Indole-to-Carbazole Strategy for the Synthesis of Substituted Carbazoles under Metal-Free Conditions.

Organic letters

Chen S, Li Y, Ni P, Huang H, Deng GJ.
PMID: 27718584
Org Lett. 2016 Oct 21;18(20):5384-5387. doi: 10.1021/acs.orglett.6b02762. Epub 2016 Oct 10.

An efficient indole-to-carbazole strategy has been developed under metal-free conditions. This carbazole formation was highly promoted by NH

Rhodium-catalyzed asymmetric hydrogenation of tetrasubstituted β-acetoxy-α-enamido esters and efficient synthesis of droxidopa.

Chemical communications (Cambridge, England)

Guan YQ, Gao M, Deng X, Lv H, Zhang X.
PMID: 28653712
Chem Commun (Camb). 2017 Jul 18;53(58):8136-8139. doi: 10.1039/c7cc03902f.

A rhodium-catalyzed asymmetric hydrogenation of challenging tetrasubstituted β-acetoxy-α-enamido esters was developed, giving chiral β-acetoxy-α-amido esters in high yields with excellent enantioselectivities (up to >99% ee). The products could be easily transformed to β-hydroxy-α-amino acid derivatives which are valuable chiral...

Showing 1 to 12 of 685 entries