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Showing 1 to 12 of 22 entries
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Pressure broadening of gas phase molecular at very low temperature.

Physical review letters

De Lucia FC, Herbst E, Oesterling LC, Pearson JC.
PMID: 10059448
Phys Rev Lett. 1995 Oct 16;75(16):2940-2943. doi: 10.1103/PhysRevLett.75.2940.

No abstract available.

C-X-C Chemokine Receptor Type 4-Targeted Imaging in Glioblastoma Multiforme Using .

ACS applied bio materials

Zhang X, Detering L, Sultan D, Heo GS, Luehmann H, Taylor S, Choksi A, Rubin JB, Liu Y.
PMID: 35014818
ACS Appl Bio Mater. 2022 Jan 17;5(1):235-242. doi: 10.1021/acsabm.1c01056. Epub 2021 Dec 23.

Glioblastoma multiforme (GBM) is the most prevalent and aggressive primary malignant brain cancer in adults, and it carries a poor prognosis. Despite the current multimodality treatment, including surgery, radiation, and chemotherapy, the overall survival is still poor. Neurooncological imaging...

C-X-C Chemokine Receptor Type 4-Targeted Imaging in Glioblastoma Multiforme Using .

ACS applied bio materials

Zhang X, Detering L, Sultan D, Heo GS, Luehmann H, Taylor S, Choksi A, Rubin JB, Liu Y.
PMID: 35014818
ACS Appl Bio Mater. 2021 Dec 23; doi: 10.1021/acsabm.1c01056. Epub 2021 Dec 23.

Glioblastoma multiforme (GBM) is the most prevalent and aggressive primary malignant brain cancer in adults, and it carries a poor prognosis. Despite the current multimodality treatment, including surgery, radiation, and chemotherapy, the overall survival is still poor. Neurooncological imaging...

Natriuretic Peptide Receptor-C is Up-Regulated in the Intima of Advanced Carotid Artery Atherosclerosis.

Journal of medical & surgical pathology

Zayed MA, Harring SD, Abendschein DR, Vemuri C, Lu D, Detering L, Liu Y, Woodard PK.
PMID: 27547837
J Med Surg Pathol. 2016 Jul;1(3). doi: 10.4172/2472-4971.1000131. Epub 2016 Jul 05.

OBJECTIVE: Natriuretic peptide receptor-C (NPR-C/NPR-3) is a cell surface protein involved in vascular remodelling that is up-regulated in atherosclerosis. NPR-C expression has not been well characterized in human carotid artery occlusive lesions. We hypothesized that NPR-C expression correlates with...

Characterization of Phosphopeptides Using a Combination of Immobilized Metal Ion Affinity Media and Direct Analysis by MALDI-TOF-MS.

CSH protocols

Deterding LJ, Cutalo JM, Tomer KB.
PMID: 21357136
CSH Protoc. 2007 Aug 01;2007:pdb.prot4618. doi: 10.1101/pdb.prot4618.

INTRODUCTIONPhosphoproteins and peptides can be bound with high specificity to immobilized metal ions such as Fe(3+), Ni(2+), and Ga(3+). This technique can be used with either on-line or off-line MS analysis. However, elution of the phosphopeptides from the metal...

SPARC-like1 mRNA is overexpressed in human uterine leiomyoma.

Molecular medicine reports

Mencalha AL, Levinsphul A, Deterling LC, Pizzatti L, Abdelhay E.
PMID: 21479452
Mol Med Rep. 2008 Jul-Aug;1(4):571-4.

Uterine leiomyomas (ULs), also known as fibroids, are benign and monoclonal tumors frequently found in the female population. The genetic alterations that contribute to UL tumor development have not been well established, and the goal of this study was...

Tandem mass spectrometry for the structural determination of backbone-modified peptides.

Journal of the American Society for Mass Spectrometry

Deterding LJ, Tomer KB, Spatola AF.
PMID: 24248746
J Am Soc Mass Spectrom. 1990 Apr;1(2):174-82. doi: 10.1016/1044-0305(90)85054-P.

A variety of backbone-modified peptides were desorbed by fast atom bombardment and collisionally activated. These peptide modifications involve the replacement of a normal [CONH] peptide linkage with such groups as thiomethylene ether (CH2S), thioamide (CSNH), methyleneamine (CH2NH), and thiomethylene...

Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U.

Nucleic acids research

Frazier MN, Dillard LB, Krahn JM, Perera L, Williams JG, Wilson IM, Stewart ZD, Pillon MC, Deterding LJ, Borgnia MJ, Stanley RE.
PMID: 34403466
Nucleic Acids Res. 2021 Sep 27;49(17):10136-10149. doi: 10.1093/nar/gkab719.

Nsp15 is a uridine specific endoribonuclease that coronaviruses employ to cleave viral RNA and evade host immune defense systems. Previous structures of Nsp15 from across Coronaviridae revealed that Nsp15 assembles into a homo-hexamer and has a conserved active site...

Serum Buprenorphine Concentrations and Behavioral Activity in Mice After a Single Subcutaneous Injection of Simbadol, Buprenorphine SR-LAB, or Standard Buprenorphine.

Journal of the American Association for Laboratory Animal Science : JAALAS

Myers PH, Goulding DR, Wiltshire RA, McGee CA, Dickerson AB, Comins MM, Shi M, Kissling GE, Lih FB, Deterding LJ, Laber-Laird KE, Blankenship-Paris TL.
PMID: 34740385
J Am Assoc Lab Anim Sci. 2021 Nov 01;60(6):661-666. doi: 10.30802/AALAS-JAALAS-21-000028. Epub 2021 Nov 05.

Buprenorphine, an analgesic commonly used in rodent surgery, requires repeated dosing every 4 to 6 h in order to provide adequate analgesia. However, redosing requires repeated handling, which may itself cause stress. Buprenorphine SR-LAB, which reportedly maintains serum levels...

Magnetic Resonance Imaging-Guided Focused Ultrasound-Based Delivery of Radiolabeled Copper Nanoclusters to Diffuse Intrinsic Pontine Glioma.

ACS applied nano materials

Zhang X, Ye D, Yang L, Yue Y, Sultan D, Pacia CP, Pang H, Detering L, Heo GS, Luehmann H, Choksi A, Sethi A, Limbrick DD, Becher OJ, Tai YC, Rubin JB, Chen H, Liu Y.
PMID: 34337344
ACS Appl Nano Mater. 2020 Nov 25;3(11):11129-11134. doi: 10.1021/acsanm.0c02297. Epub 2020 Oct 29.

Diffuse intrinsic pontine glioma (DIPG) is an invasive pediatric brainstem malignancy exclusively in children without effective treatment due to the often-intact blood-brain tumor barrier (BBTB), an impediment to the delivery of therapeutics. Herein, we used focused ultrasound (FUS) to...

Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U.

Nucleic acids research

Frazier MN, Dillard LB, Krahn JM, Perera L, Williams JG, Wilson IM, Stewart ZD, Pillon MC, Deterding LJ, Borgnia MJ, Stanley RE.
PMID: 34403466
Nucleic Acids Res. 2021 Sep 27;49(17):10136-10149. doi: 10.1093/nar/gkab719.

Nsp15 is a uridine specific endoribonuclease that coronaviruses employ to cleave viral RNA and evade host immune defense systems. Previous structures of Nsp15 from across Coronaviridae revealed that Nsp15 assembles into a homo-hexamer and has a conserved active site...

Continuous flow fast atom bombardment with packed microcolumns: A comparison of precolumn versus coaxial matrix delivery.

Journal of the American Society for Mass Spectrometry

Pleasance S, Thibault P, Moseley MA, Deterding LJ, Tomer KB, Jorgenson JW.
PMID: 24248825
J Am Soc Mass Spectrom. 1990 Jul;1(4):312-9. doi: 10.1016/1044-0305(90)85007-9.

The effect of adding glycerol to the mobile phase on the chromatographic separation of peptides has been investigated using a continuous flow fast atom bombardment (CFFAB) interface coupled with commercial packed microcolumns (25 cm × 320 μm.i.d.). In a...

Showing 1 to 12 of 22 entries