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Showing 1 to 12 of 50 entries
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Dynamics of Transforming Growth Factor Beta Signaling in Wound Healing and Scarring.

Advances in wound care

Finnson KW, McLean S, Di Guglielmo GM, Philip A.
PMID: 24527343
Adv Wound Care (New Rochelle). 2013 Jun;2(5):195-214. doi: 10.1089/wound.2013.0429.

SIGNIFICANCE: Wound healing is an intricate biological process in which the skin, or any other tissue, repairs itself after injury. Normal wound healing relies on the appropriate levels of cytokines and growth factors to ensure that cellular responses are...

Association of Positional Plagiocephaly and Developmental Delay Within a Primary Care Network.

Journal of developmental and behavioral pediatrics : JDBP

Rohde JF, Goyal NK, Slovin SR, Hossain J, Pachter LM, Di Guglielmo MD.
PMID: 33538454
J Dev Behav Pediatr. 2021 Feb-Mar 01;42(2):128-134. doi: 10.1097/DBP.0000000000000860.

OBJECTIVE: Previous research has suggested an association between plagiocephaly and developmental delay. However, study samples drawn from children seen in subspecialty clinics increase the potential for selection and referral bias. Our study evaluates the association between plagiocephaly and developmental...

Whole genome metagenomic analysis of the gut microbiome of differently fed infants identifies differences in microbial composition and functional genes, including an absent CRISPR/Cas9 gene in the formula-fed cohort.

Human microbiome journal

Di Guglielmo MD, Franke K, Cox C, Crowgey EL.
PMID: 34278055
Hum Microb J. 2019 Jun;12. doi: 10.1016/j.humic.2019.100057. Epub 2019 May 25.

BACKGROUND: Advancements in sequencing capabilities have enhanced the study of the human microbiome. There are limited studies focused on the gastro-intestinal (gut) microbiome of infants, particularly the impact of diet between breast-fed (BF) versus formula-fed (FF). It is unclear...

Gender-Specific Behaviour in Obesity Stages I-II: Imbalance of Aminothiol Status and Adipomyokine Profile in Subjects with Different Insulin Resistance Severity.

Oxidative medicine and cellular longevity

Campolo J, Corradi E, Parolini M, Di Guglielmo ML, Rizzardi A, Dellanoce C, Tarlarini P, Cattaneo M, Scioscioli E, Trivella MG, De Maria R.
PMID: 34868459
Oxid Med Cell Longev. 2021 Nov 24;2021:9713582. doi: 10.1155/2021/9713582. eCollection 2021.

The hyperproduction of oxidative stress and inflammatory biomarkers, which is paralleled by decreased levels of antioxidant and anti-inflammatory mediators, is part of cellular mechanisms that contribute to the disruption of metabolic homeostasis in obesity. Whether gender-specific alterations and gender-restricted...

The PNPLA3 rs738409 Variant but not MBOAT7 rs641738 is a Risk Factor for Nonalcoholic Fatty Liver Disease in Obese U.S. Children of Hispanic Ethnicity.

Pediatric gastroenterology, hepatology & nutrition

Mansoor S, Maheshwari A, Di Guglielmo M, Furuya K, Wang M, Crowgey E, Molle-Rios Z, He Z.
PMID: 34557398
Pediatr Gastroenterol Hepatol Nutr. 2021 Sep;24(5):455-469. doi: 10.5223/pghn.2021.24.5.455. Epub 2021 Sep 08.

PURPOSE: The rs641738 C>T in membrane-bound O-acyltransferase domain-containing protein 7 (MBOAT7) is implicated, along with the rs738409 C>G polymorphism in patatin-like phospholipase domain-containing protein 3 (PNPLA3), in nonalcoholic fatty liver disease (NAFLD). The association of these polymorphisms and NAFLD...

Effect of Coach Feedback and Awareness of Head Impact Exposure on Practice Structure in Youth Football.

Journal of neurotrauma

DiGuglielmo DM, Milef GM, Moore JB, Kelley ME, Powers AK, Stitzel JD, Urban JE.
PMID: 33397198
J Neurotrauma. 2021 May 15;38(10):1389-1398. doi: 10.1089/neu.2020.7224. Epub 2021 Mar 01.

With the concern of concussion risk and repetitive head impacts in youth football, organizations have adopted rules that limit contact during practice. However, rule changes are not ubiquitous among organizations and are challenging to monitor and enforce. Ultimately, football...

Correction to: Correlates of olfactory impairment in middle-aged non-diabetic Caucasian subjects with stage I-II obesity.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Campolo J, Corradi E, Rizzardi A, Parolini M, Dellanoce C, Di Guglielmo ML, Tarlarini P, Cattaneo M, Trivella MG, De Maria R.
PMID: 33475858
Eur Arch Otorhinolaryngol. 2021 Jun;278(6):2055. doi: 10.1007/s00405-021-06618-7.

No abstract available.

Deep brain stimulation of the nucleus accumbens shell attenuates cocaine withdrawal but increases cocaine self-administration, cocaine-induced locomotor activity, and GluR1/GluA1 in the central nucleus of the amygdala in male cocaine-dependent rats.

Brain stimulation

Kallupi M, Kononoff J, Melas PA, Qvist JS, de Guglielmo G, Kandel ER, George O.
PMID: 34742997
Brain Stimul. 2021 Nov 03;15(1):13-22. doi: 10.1016/j.brs.2021.11.003. Epub 2021 Nov 03.

BACKGROUND: Cocaine addiction is a major public health problem. Despite decades of intense research, no effective treatments are available. Both preclinical and clinical studies strongly suggest that deep brain stimulation of the nucleus accumbens (NAcc) is a viable target...

Deep brain stimulation of the nucleus accumbens shell attenuates cocaine withdrawal but increases cocaine self-administration, cocaine-induced locomotor activity, and GluR1/GluA1 in the central nucleus of the amygdala in male cocaine-dependent rats.

Brain stimulation

Kallupi M, Kononoff J, Melas PA, Qvist JS, de Guglielmo G, Kandel ER, George O.
PMID: 34742997
Brain Stimul. 2021 Nov 03;15(1):13-22. doi: 10.1016/j.brs.2021.11.003. Epub 2021 Nov 03.

BACKGROUND: Cocaine addiction is a major public health problem. Despite decades of intense research, no effective treatments are available. Both preclinical and clinical studies strongly suggest that deep brain stimulation of the nucleus accumbens (NAcc) is a viable target...

Distance-Weighted Graph Neural Networks on FPGAs for Real-Time Particle Reconstruction in High Energy Physics.

Frontiers in big data

Iiyama Y, Cerminara G, Gupta A, Kieseler J, Loncar V, Pierini M, Qasim SR, Rieger M, Summers S, Van Onsem G, Wozniak KA, Ngadiuba J, Di Guglielmo G, Duarte J, Harris P, Rankin D, Jindariani S, Liu M, Pedro K, Tran N, Kreinar E, Wu Z.
PMID: 33791596
Front Big Data. 2021 Jan 12;3:598927. doi: 10.3389/fdata.2020.598927. eCollection 2020.

Graph neural networks have been shown to achieve excellent performance for several crucial tasks in particle physics, such as charged particle tracking, jet tagging, and clustering. An important domain for the application of these networks is the FGPA-based first...

Deep brain stimulation of the nucleus accumbens shell attenuates cocaine withdrawal but increases cocaine self-administration, cocaine-induced locomotor activity, and GluR1/GluA1 in the central nucleus of the amygdala in male cocaine-dependent rats.

Brain stimulation

Kallupi M, Kononoff J, Melas PA, Qvist JS, de Guglielmo G, Kandel ER, George O.
PMID: 34742997
Brain Stimul. 2021 Nov 03;15(1):13-22. doi: 10.1016/j.brs.2021.11.003. Epub 2021 Nov 03.

BACKGROUND: Cocaine addiction is a major public health problem. Despite decades of intense research, no effective treatments are available. Both preclinical and clinical studies strongly suggest that deep brain stimulation of the nucleus accumbens (NAcc) is a viable target...

TSP-1 in lung fibrosis.

Journal of cell communication and signaling

Di Guglielmo GM.
PMID: 21234123
J Cell Commun Signal. 2010 Dec;4(4):185-6. doi: 10.1007/s12079-010-0097-8. Epub 2010 Sep 23.

Lung fibrosis is often treated with corticosteroids to reduce the inflammatory response, however, no effective treatment options exist for the underlying disease. An important player in the fibrotic cascade is the cytokine, transforming growth factor beta (TGFβ). TGFβ is...

Showing 1 to 12 of 50 entries