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Showing 1 to 12 of 73 entries
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Orientation of cellulose microfibrils in cortical cells of tobacco explants : Effects of microtubule-depolymerizing drugs.

Planta

Wilms FH, Wolters-Arts AM, Derksen J.
PMID: 24196992
Planta. 1990 Aug;182(1):1-8. doi: 10.1007/BF00239976.

The deposition of nascent cellulose microfibrils (CMFs) was studied in the walls of cortical cells in explants of Nicotiana tabacum L. flower stalks. In freshly cut explants the CMFs were deposited in two distinct and alternating orientations - all...

Organization of actin filaments in regenerating and outgrowing subprotoplasts from pollen tubes ofNicotiana tabacum L.

Planta

Rutten TL, Derksen J.
PMID: 24202090
Planta. 1990 Mar;180(4):471-9. doi: 10.1007/BF02411443.

The dynamics of actin-filament organization in pollen-tube subprotoplasts ofNicotiana tabacum L. cv. Samsun during regeneration and outgrowth was examined using phalloidin probes and a non-fixation method. A succession of actin arrays was examined during subprotoplast regeneration that strongly resembled...

Environmental correlates of physical activity in multiple sclerosis: a cross-sectional study.

The international journal of behavioral nutrition and physical activity

Doerksen SE, Motl RW, McAuley E.
PMID: 17922918
Int J Behav Nutr Phys Act. 2007 Oct 08;4:49. doi: 10.1186/1479-5868-4-49.

BACKGROUND: Multiple sclerosis (MS) is a chronic neurological disease that is associated with physical inactivity. Understanding the factors that correlate with physical activity is important for developing effective physical activity promotion programs for this population. Thus, we conducted a...

Divergent Photocyclization/1,4-Sigmatropic Rearrangements for the Synthesis of Sesquiterpenoid Derivatives.

Organic letters

Gorobets E, Wong NE, Paton RS, Derksen DJ.
PMID: 28124915
Org Lett. 2017 Feb 03;19(3):484-487. doi: 10.1021/acs.orglett.6b03635. Epub 2017 Jan 26.

Combined experimental and computational efforts have demonstrated the utility of divergent photocyclization/1,4-sigmatropic rearrangement reactions for developing a general strategy toward the synthesis of cubebane-, spiroaxane-, and guaiane-type sesquiterpenes and related analogues. The configuration of the bridgehead substituent, the choice...

Experimental investigation of heterodyne quantum key distribution in the S-band or L-band embedded in a commercial C-band DWDM system.

Optics express

Kleis S, Steinmayer J, Derksen RH, Schaeffer CG.
PMID: 31252878
Opt Express. 2019 Jun 10;27(12):16540-16549. doi: 10.1364/OE.27.016540.

The tolerance of continuous-variable quantum key distribution to co-propagating DWDM channels is investigated. The quantum channel is operated in the S-band or L-band and multiplexed with a commercial C-band DWDM system. The results show that, compared to previously proposed...

Hypervalent Iodine Mediated Oxidative Cyclization of Acrylamide .

The Journal of organic chemistry

Duddupudi AL, Pandey P, Vo H, Welsh CL, Doerksen RJ, Cuny GD.
PMID: 32392063
J Org Chem. 2020 Jun 05;85(11):7549-7557. doi: 10.1021/acs.joc.0c00581. Epub 2020 May 11.

A metal-free oxidative cyclization of

Federally Qualified Health Centers Can Expand Rural Access to Buprenorphine for Opioid Use Disorder in Arizona.

Health services insights

Brady BR, Gildersleeve R, Koch BD, Campos-Outcalt DE, Derksen DJ.
PMID: 34408434
Health Serv Insights. 2021 Aug 06;14:11786329211037502. doi: 10.1177/11786329211037502. eCollection 2021.

Medication for Opioid Use Disorder (MOUD) is recommended, but not always accessible to those who desire treatment. This study assessed the impact of expanding access to buprenorphine through federally qualified health centers (FQHCs) in Arizona. We calculated mean drive-times...

Advanced Practitioners: Collaborators in Radiation Oncology.

Journal of the advanced practitioner in oncology

Allred PA, Polansky MN, Doerksen K, Wei SH.
PMID: 33425470
J Adv Pract Oncol. 2019 Nov-Dec;10(8):873-877. doi: 10.6004/jadpro.2019.10.8.8.

Advanced practitioners (APs), including physician assistants (PAs) and nurse practitioners (NPs), are medical professionals with advanced training, degrees, and certifications that qualify them to diagnose and treat medical conditions in a wide variety of health-care settings. As such, APs...

New possibilities: the LockDown device for distal clavicle fractures.

JSES international

Blaas LS, van Sterkenburg MN, de Planque AM, Derksen RJ.
PMID: 33345204
JSES Int. 2020 Oct 15;4(4):713-718. doi: 10.1016/j.jseint.2020.08.021. eCollection 2020 Dec.

BACKGROUND AND HYPOTHESIS: The majority of distal clavicle fractures are displaced fractures and constitute a treatment challenge because they have a 30% chance of delayed union or nonunion. Although several options for surgical reconstruction have been described, in patients...

Enantioselective Interactions of Anti-Infective 8-Aminoquinoline Therapeutics with Human Monoamine Oxidases A and B.

Pharmaceuticals (Basel, Switzerland)

Chaurasiya ND, Liu H, Doerksen RJ, Nanayakkara NPD, Walker LA, Tekwani BL.
PMID: 33922294
Pharmaceuticals (Basel). 2021 Apr 22;14(5). doi: 10.3390/ph14050398.

8-Aminoquinolines (8-AQs) are an important class of anti-infective therapeutics. The monoamine oxidases (MAOs) play a key role in metabolism of 8-AQs. A major role for MAO-A in metabolism of primaquine (PQ), the prototypical 8-AQ antimalarial, has been demonstrated. These...

Pharmacophore Modeling, Ensemble Docking, Virtual Screening, and Biological Evaluation on Glycogen Synthase Kinase-3β.

Molecular informatics

Fu G, Sivaprakasam P, Dale OR, Manly SP, Cutler SJ, Doerksen RJ.
PMID: 27486080
Mol Inform. 2014 Sep;33(9):610-26. doi: 10.1002/minf.201400044. Epub 2014 Sep 02.

Glycogen synthase kinase-3 (GSK-3) is a multifunctional serine/threonine protein kinase which is engaged in a variety of signaling pathways, regulating a wide range of cellular processes. GSK-3β, also known as tau protein kinase I (TPK-I), is one of the...

Quantitative Structure-Activity Relationship Analysis and a Combined Ligand-Based/Structure-Based Virtual Screening Study for Glycogen Synthase Kinase-3.

Molecular informatics

Fu G, Liu S, Nan X, Dale OR, Zhao Z, Chen Y, Wilkins DE, Manly SP, Cutler SJ, Doerksen RJ.
PMID: 27486081
Mol Inform. 2014 Sep;33(9):627-40. doi: 10.1002/minf.201400045. Epub 2014 Sep 02.

Glycogen synthase kinase-3 (GSK-3) is a multifunctional serine/threonine protein kinase which regulates a wide range of cellular processes, involving various signalling pathways. GSK-3β has emerged as an important therapeutic target for diabetes and Alzheimer's disease. To identify structurally novel...

Showing 1 to 12 of 73 entries