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Showing 1 to 5 of 5 entries
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Tension Measurement in Isolated Rat and Mouse Pulmonary Artery.

Drug discovery today. Disease models

Ko EA, Song MY, Donthamsetty R, Makino A, Yuan JX.
PMID: 23175638
Drug Discov Today Dis Models. 2010;7(3):123-130. doi: 10.1016/j.ddmod.2011.04.001. Epub 2011 May 06.

Arterial vasoconstriction is an important physiological process in regulating blood pressure, and is involved in pathologies. The isolation of arteries from rats and mice, as well as the measurement of vascular tension in an ex vivo preparation, are important...

Interleukin-10 Producing Regulatory B Cells Transformed CD4.

Frontiers in immunology

Tarique M, Naz H, Kurra SV, Saini C, Naqvi RA, Rai R, Suhail M, Khanna N, Rao DN, Sharma A.
PMID: 30083152
Front Immunol. 2018 Jul 23;9:1636. doi: 10.3389/fimmu.2018.01636. eCollection 2018.

Regulatory B cells (Bregs) are known to exhibit their regulatory functions through interleukin-10 (IL-10) cytokine which suppress inflammation. There are only a few studies explaining the phenotype and functioning of these cells in contribution to host immunity in leprosy....

Selective Photoswitchable Allosteric Agonist of a G Protein-Coupled Receptor.

Journal of the American Chemical Society

Donthamsetti P, Konrad DB, Hetzler B, Fu Z, Trauner D, Isacoff EY.
PMID: 34115935
J Am Chem Soc. 2021 Jun 23;143(24):8951-8956. doi: 10.1021/jacs.1c02586. Epub 2021 Jun 11.

G protein-coupled receptors (GPCRs) are the most common targets of drug discovery. However, the similarity between related GPCRs combined with the complex spatiotemporal dynamics of receptor activation

Protection against Fas-induced fulminant hepatic failure in liver specific integrin linked kinase knockout mice.

Comparative hepatology

Donthamsetty S, Mars WM, Orr A, Wu C, Michalopoulos GK.
PMID: 22104495
Comp Hepatol. 2011 Nov 21;10:11. doi: 10.1186/1476-5926-10-11.

BACKGROUND: Programmed cell death or apoptosis is an essential process for tissue homeostasis. Hepatocyte apoptosis is a common mechanism to many forms of liver disease. This study was undertaken to test the role of ILK in hepatocyte survival and...

Pulmonary Edema from Intravasation of Irrigation Fluid During Hip Arthroscopy in a Child: A Case Report.

JBJS case connector

Suraj Trivedi LT, Gourineni P, Donthamsetti A.
PMID: 29252353
JBJS Case Connect. 2012 Oct-Dec;2(4):e57. doi: 10.2106/JBJS.CC.L.00006.

No abstract available.

Showing 1 to 5 of 5 entries