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Showing 1 to 10 of 10 entries
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LK-DFBA: a linear programming-based modeling strategy for capturing dynamics and metabolite-dependent regulation in metabolism.

BMC bioinformatics

Dromms RA, Lee JY, Styczynski MP.
PMID: 32122331
BMC Bioinformatics. 2020 Mar 02;21(1):93. doi: 10.1186/s12859-020-3422-0.

BACKGROUND: The systems-scale analysis of cellular metabolites, "metabolomics," provides data ideal for applications in metabolic engineering. However, many of the computational tools for strain design are built around Flux Balance Analysis (FBA), which makes assumptions that preclude direct integration...

Sarcoid-like reaction in a patient recovering from coronavirus disease 19 pneumonia.

JAAD case reports

Behbahani S, Baltz JO, Droms R, Deng AC, Amano SU, Levin NA, O'Brien MC, Wiss K.
PMID: 32837988
JAAD Case Rep. 2020 Sep;6(9):915-917. doi: 10.1016/j.jdcr.2020.07.026. Epub 2020 Jul 24.

No abstract available.

Systematic applications of metabolomics in metabolic engineering.

Metabolites

Dromms RA, Styczynski MP.
PMID: 24957776
Metabolites. 2012 Dec 14;2(4):1090-122. doi: 10.3390/metabo2041090.

The goals of metabolic engineering are well-served by the biological information provided by metabolomics: information on how the cell is currently using its biochemical resources is perhaps one of the best ways to inform strategies to engineer a cell...

Utility of routine patch testing prior to surgical repair of pectus excavatum: A multidisciplinary experience via retrospective review at a single tertiary care center.

Pediatric dermatology

Leonard N, Droms R, Lal K, Wiss K, Aidlen JT, Silvestri D, Belazarian L.
PMID: 34647642
Pediatr Dermatol. 2021 Oct 14; doi: 10.1111/pde.14826. Epub 2021 Oct 14.

BACKGROUND: The Nuss procedure is the only implant procedure in which routine, rather than selective, preoperative patch testing is recommended. This practice has recently been called into question.OBJECTIVE: To evaluate an updated experience of pre-implant patch testing in patients...

Two novel RUNX1 mutations in a patient with congenital thrombocytopenia that evolved into a high grade myelodysplastic syndrome.

Leukemia research reports

Schmit JM, Turner DJ, Hromas RA, Wingard JR, Brown RA, Li Y, Li MM, Slayton WB, Cogle CR.
PMID: 25893166
Leuk Res Rep. 2015 Apr 03;4(1):24-7. doi: 10.1016/j.lrr.2015.03.002. eCollection 2015.

Here we report two new RUNX1 mutations in one patient with congenital thrombocytopenia that transformed into a high grade myelodysplastic syndrome with myelomonocytic features. The first mutation was a nucleotide base substitution from guanine to adenine within exon 8,...

NSC30049 inhibits Chk1 pathway in 5-FU-resistant CRC bulk and stem cell populations.

Oncotarget

Narayan S, Jaiswal AS, Sharma R, Nawab A, Duckworth LV, Law BK, Zajac-Kaye M, George TJ, Sharma J, Sharma AK, Hromas RA.
PMID: 28915668
Oncotarget. 2017 Aug 01;8(34):57246-57264. doi: 10.18632/oncotarget.19778. eCollection 2017 Aug 22.

The 5-fluorouracil (5-FU) treatment induces DNA damage and stalling of DNA replication forks. These stalled replication forks then collapse to form one sided double-strand breaks, leading to apoptosis. However, colorectal cancer (CRC) stem cells rapidly repair the stalled/collapsed replication...

Utility of routine patch testing prior to surgical repair of pectus excavatum: A multidisciplinary experience via retrospective review at a single tertiary care center.

Pediatric dermatology

Leonard N, Droms R, Lal K, Wiss K, Aidlen JT, Silvestri D, Belazarian L.
PMID: 34647642
Pediatr Dermatol. 2021 Nov;38(6):1510-1514. doi: 10.1111/pde.14826. Epub 2021 Oct 14.

BACKGROUND: The Nuss procedure is the only implant procedure in which routine, rather than selective, preoperative patch testing is recommended. This practice has recently been called into question.OBJECTIVE: To evaluate an updated experience of pre-implant patch testing in patients...

Oral roberts and objectivity.

Science (New York, N.Y.)

Hromas RA.
PMID: 17830791
Science. 1980 Jun 13;208(4449):1212. doi: 10.1126/science.208.4449.1212-a.

No abstract available.

Structural Basis of RNA Cap Modification by SARS-CoV-2 Coronavirus.

bioRxiv : the preprint server for biology

Viswanathan T, Arya S, Chan SH, Qi S, Dai N, Hromas RA, Park JG, Oladunni F, Martinez-Sobrido L, Gupta YK.
PMID: 32511383
bioRxiv. 2020 Apr 26; doi: 10.1101/2020.04.26.061705.

The novel severe acute respiratory syndrome coronoavirus-2 (SARS-CoV-2), the causative agent of COVID-19 illness, has caused over 2 million infections worldwide in four months. In SARS coronaviruses, the non-structural protein 16 (nsp16) methylates the 5'-end of virally encoded mRNAs...

Ionic conjugates of lidocaine and sweeteners as better tasting local anesthetics for dentistry.

Journal of materials chemistry. B

Lebedyeva IO, Oliferenko AA, Oliferenko PV, Hromas RA, Neubert JK, Caudle RM, Wickersham J, Castleman WL, Altschuler GI, Ostrov DA, Hall CD, Katritzky AR.
PMID: 32262689
J Mater Chem B. 2015 Nov 21;3(43):8492-8498. doi: 10.1039/c5tb00674k. Epub 2015 Sep 29.

Lidocaine is the most widely utilized intraoral injected dental anesthetic, used for more than 500 million dental injections per year. Local anesthesia is essential for pain-free dentistry, yet intraoral injections are often considered painful and a source of anxiety...

Showing 1 to 10 of 10 entries