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Showing 1 to 12 of 755 entries
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The loss-of-function of DNA methyltransferase 1 by siRNA impairs the growth of non-small cell lung cancer with alleviated side effects via reactivation of RASSF1A and APC .

Oncotarget

Lai Q, Xu YH, Chen Q, Tang L, Li AG, Zhang LF, Zhang CF, Song JF, Du ZZ.
PMID: 28938637
Oncotarget. 2017 Jul 26;8(35):59301-59311. doi: 10.18632/oncotarget.19573. eCollection 2017 Aug 29.

Hypermethylation of tumor suppressor genes (TSGs) promoters by DNA methyltransferase (DNMT) can be observed in almost all cancers which represent a hallmark of carcinogenesis, including lung cancer. DNMT inhibitors (e.g.5-Aza-CR/CdR) reactivate TSGs to exert anti-cancer activity and have been...

Crystal Field Splitting is Limiting the Stability and Strength of Ultra-incompressible Orthorhombic Transition Metal Tetraborides.

Scientific reports

Zhang RF, Wen XD, Legut D, Fu ZH, Veprek S, Zurek E, Mao HK.
PMID: 26976479
Sci Rep. 2016 Mar 15;6:23088. doi: 10.1038/srep23088.

The lattice stability and mechanical strengths of the supposedly superhard transition metal tetraborides (TmB4, Tm = Cr, Mn and Fe) evoked recently much attention from the scientific community due to the potential applications of these materials, as well as...

Optical performance of toric intraocular lenses in the presence of decentration.

International journal of ophthalmology

Zhang B, Ma JX, Liu DY, Du YH, Guo CR, Cui YX.
PMID: 26309871
Int J Ophthalmol. 2015 Aug 18;8(4):730-5. doi: 10.3980/j.issn.2222-3959.2015.04.16. eCollection 2015.

AIM: To evaluate the optical performance of toric intraocular lenses (IOLs) after decentration and with different pupil diameters, but with the IOL astigmatic axis aligned.METHODS: Optical performances of toric T5 and SN60AT spherical IOLs after decentration were tested on...

A Small Indel Mutant Mouse Model of Epidermolytic Palmoplantar Keratoderma and Its Application to Mutant-specific shRNA Therapy.

Molecular therapy. Nucleic acids

Lyu YS, Shi PL, Chen XL, Tang YX, Wang YF, Liu RR, Luan XR, Fang Y, Mei RH, Du ZF, Ke HP, Matro E, Li LE, Lin ZY, Zhao J, Gao X, Zhang XN.
PMID: 27003758
Mol Ther Nucleic Acids. 2016 Mar 22;5:e299. doi: 10.1038/mtna.2016.17.

Epidermolytic palmoplantar keratoderma (EPPK) is a relatively common autosomal-dominant skin disorder caused by mutations in the keratin 9 gene (KRT9), with few therapeutic options for the affected so far. Here, we report a knock-in transgenic mouse model that carried...

A Bioinformatic Approach for the Discovery of Antiaging Effects of Baicalein from Scutellaria baicalensis Georgi.

Rejuvenation research

Gao L, Duan DD, Zhang JQ, Zhou YZ, Qin XM, Du GH.
PMID: 26778291
Rejuvenation Res. 2016 Oct;19(5):414-422. doi: 10.1089/rej.2015.1760. Epub 2016 Mar 15.

Aging is one of the most complicated phenomena and is the main risk factor for age-related diseases. Based on the public aging-related gene data, we propose a computational approach to predict the antiaging activities of compounds. This approach integrates...

Synthesis, Crystal and Electronic Structures, and Optical Properties of (CH.

Inorganic chemistry

Roccanova R, Ming W, Whiteside VR, McGuire MA, Sellers IR, Du MH, Saparov B.
PMID: 29094933
Inorg Chem. 2017 Nov 20;56(22):13878-13888. doi: 10.1021/acs.inorgchem.7b01986. Epub 2017 Nov 02.

We report the synthesis, crystal and electronic structures, as well as optical properties of the hybrid organic-inorganic compounds MA

Anion Effects on Lanthanide(III) Tetrazole-1-acetate Dinuclear Complexes Showing Slow Magnetic Relaxation and Photofluorescent Emission.

Inorganic chemistry

Lu YB, Jiang XM, Zhu SD, Du ZY, Liu CM, Xie YR, Liu LX.
PMID: 27023680
Inorg Chem. 2016 Apr 18;55(8):3738-49. doi: 10.1021/acs.inorgchem.5b02432. Epub 2016 Mar 29.

Three types of lanthanide complexes based on the tetrazole-1-acetic acid ligand and the 2,2'-bipyridine coligand were prepared and characterized by single-crystal X-ray diffraction, IR spectroscopy, and elemental analyses; the formulas of these complexes are [Ln2(1-tza)4(NO3)2(2,2'-bipy)2] (Ln = Sm (1),...

A comparison of satellite observations with the XCO.

The Science of the total environment

Zhang LL, Yue TX, Wilson JP, Zhao N, Zhao YP, Du ZP, Liu Y.
PMID: 28609846
Sci Total Environ. 2017 Dec 01;601:1575-1590. doi: 10.1016/j.scitotenv.2017.06.018. Epub 2017 Jun 09.

Ground observations can capture CO

Layer-by-Layer Assembled Conductive Metal-Organic Framework Nanofilms for Room-Temperature Chemiresistive Sensing.

Angewandte Chemie (International ed. in English)

Yao MS, Lv XJ, Fu ZH, Li WH, Deng WH, Wu GD, Xu G.
PMID: 29071780
Angew Chem Int Ed Engl. 2017 Dec 22;56(52):16510-16514. doi: 10.1002/anie.201709558. Epub 2017 Nov 15.

The utility of electronically conductive metal-organic frameworks (EC-MOFs) in high-performance devices has been limited to date by a lack of high-quality thin film. The controllable thin-film fabrication of an EC-MOF, Cu

Elevation of serum apelin-13 associated with proliferative diabetic retinopathy in type 2 diabetic patients.

International journal of ophthalmology

Du JH, Li X, Li R, Xu L, Ma RR, Liu SF, Zhang Z, Sun HZ.
PMID: 25540748
Int J Ophthalmol. 2014 Dec 18;7(6):968-73. doi: 10.3980/j.issn.2222-3959.2014.06.10. eCollection 2014.

AIM: To compare apelin-13, a ligand of G-protein-coupled receptor which has been shown to be involved in retinal angiogenesis, and vascular endothelial growth factor (VEGF) serum levels in type 2 diabetes mellitus (T2DM) with or without retinopathy, and to...

In situ catalytic growth of large-area multilayered graphene/MoS2 heterostructures.

Scientific reports

Fu W, Du FH, Su J, Li XH, Wei X, Ye TN, Wang KX, Chen JS.
PMID: 24728289
Sci Rep. 2014 Apr 14;4:4673. doi: 10.1038/srep04673.

Stacking various two-dimensional atomic crystals on top of each other is a feasible approach to create unique multilayered heterostructures with desired properties. Herein for the first time, we present a controlled preparation of large-area graphene/MoS2 heterostructures via a simple...

Pd(OAc)2-catalyzed regioselective aromatic C-H bond fluorination.

Chemical communications (Cambridge, England)

Lou SJ, Xu DQ, Xia AB, Wang YF, Liu YK, Du XH, Xu ZY.
PMID: 23736892
Chem Commun (Camb). 2013 Jul 14;49(55):6218-20. doi: 10.1039/c3cc42220h.

A novel Pd(OAc)2-NFSI-TFA system was developed for the highly selective ortho-monofluorination directed by diverse aryl-N-heterocyclic directing groups e.g., quinoxaline, pyrazole, benzo[d]oxazole, and pyrazine derivatives. A Pd(II/IV) catalytic cycle was proposed based on the ESI-MS/MS studies.

Showing 1 to 12 of 755 entries