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Showing 1 to 12 of 158 entries
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Role of protein z in stroke.

Current treatment options in cardiovascular medicine

Tran HA, Eikelboom JW.
PMID: 17601382
Curr Treat Options Cardiovasc Med. 2007 Jun;9(3):191-7. doi: 10.1007/s11936-007-0012-7.

Protein Z (PZ) is a vitamin K-dependent plasma glycoprotein that acts as a cofactor for PZ-dependent protease inhibitor to inhibit coagulation factor X(a). Studies in mice suggest that that decreased blood PZ levels lead to reduced inhibition of blood...

Sex, stroke, and atrial fibrillation.

Archives of neurology

Hart RG, Eikelboom JW, Pearce LA.
PMID: 23007639
Arch Neurol. 2012 Dec;69(12):1641-3. doi: 10.1001/archneurol.2012.2691.

CONTEXT: Stroke is a serious complication associated with atrial fibrillation (AF). Women with AF are at higher risk of stroke compared with men. Reasons for this higher stroke risk in women remain unclear, although some studies suggest that undertreatment...

Animal models of chronic tympanic membrane perforation: in response to plasminogen initiates and potentiates the healing of acute and chronic tympanic membrane perforations in mice.

Clinical and translational medicine

Wang AY, Shen Y, Wang JT, Eikelboom RH, Dilley RJ.
PMID: 24669846
Clin Transl Med. 2014 Mar 26;3(1):5. doi: 10.1186/2001-1326-3-5.

Tympanic membrane perforations (TMP) are relatively common but are typically not treated in their acute stage, as most will heal spontaneously in 7-10 days. Those cases which fail to heal within 3 months are called chronic TMP which attract...

Trends in Perioperative Venous Thromboembolism Associated with Major Noncardiac Surgery.

TH open : companion journal to thrombosis and haemostasis

Smilowitz NR, Gupta N, Guo Y, Maldonado TS, Eikelboom JW, Goldhaber SZ, Bangalore S, Berger JS.
PMID: 30246174
TH Open. 2017 Jul;1(2):e82-e91. doi: 10.1055/s-0037-1605360.

BACKGROUND: Venous thromboembolism (VTE) is a common vascular complication of non-cardiac surgery.METHODS: We evaluated national trends in perioperative in-hospital VTE incidence, management, and outcomes using a large database of hospital admissions from the United States. Patients aged ≥ 45...

Unmet Needs in Anticoagulant Therapy: Potential Role of Rivaroxaban.

Cardiology research

Eikelboom JW, Connolly SJ.
PMID: 28197239
Cardiol Res. 2015 Jun;6(3):267-277. doi: 10.14740/cr413w. Epub 2015 Jun 11.

The new generation of non-vitamin K antagonist oral anticoagulants (NOACs) have been welcomed as a convenient alternative to warfarin. Three new oral anticoagulants, dabigatran etexilate, rivaroxaban and apixaban have been approved for the prevention of stroke and systemic embolism...

Collaborative use of geodesign tools to support decision-making on adaptation to climate change.

Mitigation and adaptation strategies for global change

Eikelboom T, Janssen R.
PMID: 30197564
Mitig Adapt Strateg Glob Chang. 2017;22(2):247-266. doi: 10.1007/s11027-015-9633-4. Epub 2015 Feb 13.

Spatial planners around the world need to make climate change adaptation plans. Climate adaptation planning requires combining spatial information with stakeholder values. This study demonstrates the potential of geodesign tools as a mean to integrate spatial analysis with stakeholder...

Response to: Unacceptable conflicts of interest (Br J Anaesth 2018; 121: 1183).

British journal of anaesthesia

Eikelboom J.
PMID: 30336866
Br J Anaesth. 2018 Nov;121(5):1183-1184. doi: 10.1016/j.bja.2018.07.031. Epub 2018 Sep 06.

No abstract available.

60 Years After the First Woman Cardiac Surgeon: We Still Need More Women in Cardiac Surgery.

CJC open

Gao SW, Forcillo J, Watkins AC, Antonoff MB, Luc JGY, Chung JCY, Ritchie L, Eikelboom R, Shashidharan S, Maruyama M, Whitlock RP, Ouzounian M, Belley-Côté EP.
PMID: 34993438
CJC Open. 2021 Jul 24;3(12):S89-S94. doi: 10.1016/j.cjco.2021.07.012. eCollection 2021 Dec.

In 1960, Dr Nina Starr Braunwald became the first woman to perform open heart surgery. Sixty years later, despite the fact that women outnumbered men in American medical school in 2017, men still dominate the field of cardiac surgery....

2020 Asian Pacific Society of Cardiology Consensus Recommendations on Antithrombotic Management for High-risk Chronic Coronary Syndrome.

European cardiology

Tan JWC, Chew DP, Brieger D, Eikelboom J, Montalescot G, Ako J, Kim BK, Quek DK, Aitken SJ, Chow CK, Chour S, Tse HF, Kaul U, Firdaus I, Kubo T, Liew BW, Chong TT, Sin KY, Yeh HI, Buddhari W, Chunhamaneewat N, Hasan F, Fox KA, Nguyen QN, Lo ST.
PMID: 34249148
Eur Cardiol. 2021 Jun 18;16:e26. doi: 10.15420/ecr.2020.45. eCollection 2021 Feb.

The unique characteristics of patients with chronic coronary syndrome (CCS) in the Asia-Pacific region, heterogeneous approaches because of differences in accesses and resources and low number of patients from the Asia-Pacific region in pivotal studies, mean that international guidelines...

Low-dose rivaroxaban plus aspirin in patients with polypharmacy and multimorbidity: an analysis from the COMPASS trial.

European heart journal. Cardiovascular pharmacotherapy

Vanassche T, Verhamme P, Anand SS, Shestakovska O, Leong DP, Fox KAA, Bhatt DL, Avezum A, Alings M, Aboyans V, Maggioni AP, Widimsky P, Muehlhofer E, Berkowitz SD, Yusuf S, Connolly SJ, Eikelboom JW, Bosch J.
PMID: 34191011
Eur Heart J Cardiovasc Pharmacother. 2021 Jun 30; doi: 10.1093/ehjcvp/pvab050. Epub 2021 Jun 30.

BACKGROUND: In patients with coronary or peripheral arterial disease, adding low dose rivaroxaban to aspirin reduces cardiovascular events and mortality. Polypharmacy and multimorbidity are frequent in such patients.AIMS: To analyze whether the benefits and risks of rivaroxaban plus aspirin...

Antiplatelet Therapy in Patients with Atrial Fibrillation: A Systematic Review and Metaanalysis of Randomized Trials.

European heart journal. Cardiovascular pharmacotherapy

Benz AP, Johansson I, Dewilde WJM, Lopes RD, Mehran R, Sartori S, Sarafoff N, Yasuda S, McIntyre WF, Healey JS, Shoamanesh A, Eikelboom JW, Connolly SJ.
PMID: 34142118
Eur Heart J Cardiovasc Pharmacother. 2021 Jun 17; doi: 10.1093/ehjcvp/pvab044. Epub 2021 Jun 17.

AIMS: To systematically assess the effects of antiplatelets on clinical outcomes in patients with atrial fibrillation (AF), treated and not treated with oral anticoagulation.METHODS AND RESULTS: We searched MEDLINE, Embase and CENTRAL from inception until September 2020. From 5,446...

Commentary: The high cost of low output.

The Journal of thoracic and cardiovascular surgery

Eikelboom R, Arora RC.
PMID: 32896375
J Thorac Cardiovasc Surg. 2020 Aug 15; doi: 10.1016/j.jtcvs.2020.08.037. Epub 2020 Aug 15.

No abstract available.

Showing 1 to 12 of 158 entries