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Showing 1 to 12 of 57 entries
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Modified Sagnac interferometer for contact-free length measurement of a direct absorption cell.

Applied optics

Elandaloussi H, Rouillé C, Marie-Jeanne P, Janssen C.
PMID: 26974791
Appl Opt. 2016 Mar 10;55(8):1971-7. doi: 10.1364/AO.55.001971.

Accurate path length measurements in absorption cells are recurrent requirements in quantitative molecular absorption spectroscopy. A new twin path laser interferometer for length measurements in a simple direct path absorption geometry is presented, along with a full uncertainty budget....

New complex chromosomal translocation in chronic myeloid leukaemia: t(9;18;22)(q34;p11;q11).

Journal of biomedicine & biotechnology

El Andaloussi A, Bilhou-Nabera C.
PMID: 18273416
J Biomed Biotechnol. 2007;2007(7):92385. doi: 10.1155/2007/92385.

A Chronic myeloid leukaemia (CML) case with a new complex t(9;18;22)(q34;p11;q11) of a 29-year-old man is being reported. For the first time, this translocation has been characterized by karyotype complemented with fluorescence in situ hybridization (FISH). In CML, the...

Modulating Anti-MicroRNA-21 Activity and Specificity Using Oligonucleotide Derivatives and Length Optimization.

ISRN pharmaceutics

Muñoz-Alarcón A, Guterstam P, Romero C, Behlke MA, Lennox KA, Wengel J, El Andaloussi S, Langel U.
PMID: 22474606
ISRN Pharm. 2012;2012:407154. doi: 10.5402/2012/407154. Epub 2012 Feb 07.

MicroRNAs are short, endogenous RNAs that direct posttranscriptional regulation of gene expression vital for many developmental and cellular functions. Implicated in the pathogenesis of several human diseases, this group of RNAs provides interesting targets for therapeutic intervention. Anti-microRNA oligonucleotides...

Optimisation of imaging flow cytometry for the analysis of single extracellular vesicles by using fluorescence-tagged vesicles as biological reference material.

Journal of extracellular vesicles

Görgens A, Bremer M, Ferrer-Tur R, Murke F, Tertel T, Horn PA, Thalmann S, Welsh JA, Probst C, Guerin C, Boulanger CM, Jones JC, Hanenberg H, Erdbrügger U, Lannigan J, Ricklefs FL, El-Andaloussi S, Giebel B.
PMID: 30949308
J Extracell Vesicles. 2019 Mar 21;8(1):1587567. doi: 10.1080/20013078.2019.1587567. eCollection 2019.

Extracellular vesicles (EVs) mediate targeted cellular interactions in normal and pathophysiological conditions and are increasingly recognised as potential biomarkers, therapeutic agents and drug delivery vehicles. Based on their size and biogenesis, EVs are classified as exosomes, microvesicles and apoptotic...

Characterization of a Novel Cytotoxic Cell-penetrating Peptide Derived From p14ARF Protein.

Molecular therapy : the journal of the American Society of Gene Therapy

Johansson HJ, El-Andaloussi S, Holm T, Mäe M, Jänes J, Maimets T, Langel Ü.
PMID: 28192705
Mol Ther. 2008 Jan;16(1):115-123. doi: 10.1038/sj.mt.6300346. Epub 2016 Dec 07.

The tumor suppressor p14ARF is widely deregulated in many types of cancers and is believed to function as a failsafe mechanism, inhibiting proliferation and inducing apoptosis as cellular response to a high oncogene load. We have found that a...

Children with vesicoureteric reflux have joint hypermobility and occasional tenascin XB sequence variants.

Canadian Urological Association journal = Journal de l'Association des urologues du Canada

Tokhmafshan F, El Andalousi J, Murugapoopathy V, Fillion ML, Campillo S, Capolicchio JP, Jednak R, El Sherbiny M, Turpin S, Schalkwijk J, Matsumoto KI, Brophy PD, Gbadegesin RA, Gupta IR.
PMID: 31702543
Can Urol Assoc J. 2020 Apr;14(4):E128-E136. doi: 10.5489/cuaj.6068. Epub 2019 Nov 05.

INTRODUCTION: To consider alternative mechanisms that give rise to a refluxing ureterovesical junction (UVJ), we hypothesized that children with a common heritable urinary tract defect, vesicoureteric reflux (VUR), may have a defect in the extracellular matrix composition of the...

Nonlinear Frequency-Sweep Correction of Tunable Electromagnetic Sources.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control

Minissale M, Zanon-Willette T, Prokhorov I, Elandaloussi H, Janssen C.
PMID: 29993544
IEEE Trans Ultrason Ferroelectr Freq Control. 2018 Aug;65(8):1487-1491. doi: 10.1109/TUFFC.2018.2843183. Epub 2018 Jun 01.

Tunable electromagnetic (EM) sources, such as voltage-controlled oscillators, micro-electromechanical systems, or diode lasers are often required to be linear during frequency-sweep modulation. In many cases, it might also be sufficient that the degree of the nonlinearity can be well...

Considerations and Implications in the Purification of Extracellular Vesicles - A Cautionary Tale.

Frontiers in neuroscience

Lee YXF, Johansson H, Wood MJA, El Andaloussi S.
PMID: 31680809
Front Neurosci. 2019 Oct 18;13:1067. doi: 10.3389/fnins.2019.01067. eCollection 2019.

Extracellular vesicles (EVs) are nano-sized particles constitutively released from cells into all biological fluids. Interestingly, these vesicles contain genetic cargoes including proteins, RNA and bioactive lipids that can be functionally delivered and affect recipient cells. As a result, there...

GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain.

Nature communications

Dar GH, Mendes CC, Kuan WL, Speciale AA, Conceição M, Görgens A, Uliyakina I, Lobo MJ, Lim WF, El Andaloussi S, Mäger I, Roberts TC, Barker RA, Goberdhan DCI, Wilson C, Wood MJA.
PMID: 34795295
Nat Commun. 2021 Nov 18;12(1):6666. doi: 10.1038/s41467-021-27056-3.

Extracellular vesicles (EVs) are biological nanoparticles with important roles in intercellular communication, and potential as drug delivery vehicles. Here we demonstrate a role for the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in EV assembly and secretion. We observe high levels...

Extracellular vesicles are the primary source of blood-borne tumour-derived mutant KRAS DNA early in pancreatic cancer.

Journal of extracellular vesicles

Hagey DW, Kordes M, Görgens A, Mowoe MO, Nordin JZ, Moro CF, Löhr JM, El Andaloussi S.
PMID: 34595842
J Extracell Vesicles. 2021 Oct;10(12):e12142. doi: 10.1002/jev2.12142.

Up to now, the field of liquid biopsies has focused on circulating tumour DNA and cells, though extracellular vesicles (EVs) have been of increasing interest in recent years. Thus, reported sources of tumour-derived nucleic acids include leukocytes, platelets and...

Correction to: Isolation and Characterization of Extracellular Vesicles from Keratinocyte Cultures.

Methods in molecular biology (Clifton, N.J.)

Sjöqvist S, Imafuku A, Gupta D, El Andaloussi S.
PMID: 31833008
Methods Mol Biol. 2020;2109:293. doi: 10.1007/7651_2019_274.

The original version of this chapter was inadvertently published with incorrect spelling of surname of the authors. The names should read Sebastian Sjöqvist, Aya Imafuku, Danu Gupta, and Samir EL Andaloussi, and not Sebastian Sjöqvist, Aya Imafuku, Dhanu Ghupta,...

GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain.

Nature communications

Dar GH, Mendes CC, Kuan WL, Speciale AA, Conceição M, Görgens A, Uliyakina I, Lobo MJ, Lim WF, El Andaloussi S, Mäger I, Roberts TC, Barker RA, Goberdhan DCI, Wilson C, Wood MJA.
PMID: 34795295
Nat Commun. 2021 Nov 18;12(1):6666. doi: 10.1038/s41467-021-27056-3.

Extracellular vesicles (EVs) are biological nanoparticles with important roles in intercellular communication, and potential as drug delivery vehicles. Here we demonstrate a role for the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in EV assembly and secretion. We observe high levels...

Showing 1 to 12 of 57 entries