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Showing 1 to 12 of 17 entries
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Hepatitis C genotype 4: The past, present, and future.

World journal of hepatology

Abdel-Ghaffar TY, Sira MM, El Naghi S.
PMID: 26668691
World J Hepatol. 2015 Dec 08;7(28):2792-810. doi: 10.4254/wjh.v7.i28.2792.

Hepatitis C virus (HCV) genotype (GT) 4 represents 12%-15% (15-18 million) of total global HCV infection. It is prevalent in Northern and Equatorial Africa and the Middle East, and is also present in some countries in Europe. GT-4 (and...

Liver-directed conversion therapy in metastatic colon cancer.

Journal of gastrointestinal oncology

Snyder A, Kemeny N, Shamseddine A, Al-Olayan A, El-Merhi F, Kelsen DP, Jamali F, Sidani M, Mukherji D, El-Naghy M, O'Reilly EM, Saltz LB, Abou-Alfa GK.
PMID: 26029460
J Gastrointest Oncol. 2015 Jun;6(3):322-8. doi: 10.3978/j.issn.2078-6891.2015.006.

No abstract available.

An unusual erupted complex composite odontoma: a rare case.

Case reports in dentistry

Ali Azhar D, Kota MZ, El-Nagdy S.
PMID: 23346425
Case Rep Dent. 2013;2013:106019. doi: 10.1155/2013/106019. Epub 2013 Jan 03.

Odontomas are malformations of the dental tissues and may interfere with the eruption of the associated tooth. Complex composite odontoma (CO) was described as a distinct entity for the first time by Broca in 1866. This lesion takes place...

Early Predictors of Renal Dysfunction in Pediatric Patients with Sickle Cell Disease.

Indian journal of nephrology

El-Gamasy MA, El-Naghy WS.
PMID: 30814790
Indian J Nephrol. 2019 Jan-Feb;29(1):28-33. doi: 10.4103/ijn.IJN_40_18.

Sickle cell disease (SCD) is a hereditary hemoglobinopathy characterized by abnormal hemoglobin production which leads to hemolytic anemia and intermittent occlusion of small blood vessels, which further leads to tissue ischemia, chronic organ damage, and organ dysfunction including urinary...

Dental anomaly patterns in mixed dentition: Illustrating the role of interceptive orthodontics in the management of mandibular lateral incisor-canine transpositions and palatally displaced maxillary canines.

International orthodontics

Hasanin M, ElNaghy R.
PMID: 33967012
Int Orthod. 2021 Jun;19(2):310-318. doi: 10.1016/j.ortho.2021.04.004. Epub 2021 May 07.

Dental anomalies of size, number, and position have been suggested to have a genetic background and frequently complicate the orthodontic treatment. Early intervention is a paramount step in managing patients with dental anomaly patterns (DAPs) to decrease the complexity...

Urinary Neutrophil Gelatinase-Associated Lipocalin and Urinary Soluble CXCL16 as Biomarkers of Activity in Pediatric Lupus Nephritis.

Indian journal of nephrology

El-Gamasy MA, El-Naghy W.
PMID: 30647496
Indian J Nephrol. 2018 Nov-Dec;28(6):427-432. doi: 10.4103/ijn.IJN_265_17.

One of the challenges of treating patients with lupus nephritis (LN) is to assess disease activity. The aim of this study was to measure the urinary neutrophil gelatinase-associated lipocalin (uNGAL) and urinary soluble chemokine (C-X-C motif) ligand 16 (CXCL16)...

MPI-CDG from a hepatic perspective: Report of two Egyptian cases and review of literature.

JIMD reports

Abdel Ghaffar TY, Ng BG, Elsayed SM, El Naghi S, Helmy S, Mohammed N, El Hennawy A, Freeze HH.
PMID: 33204592
JIMD Rep. 2020 Sep 07;56(1):20-26. doi: 10.1002/jmd2.12159. eCollection 2020 Nov.

MPI-CDG is a rare congenital disorder of glycosylation (CDG) which presents with hepato-gastrointestinal symptoms and hypoglycemia. We report on hepatic evaluation of two pediatric patients who presented to us with gastrointestinal symptoms. Analysis of carbohydrate deficient transferrin (CDT) showed...

The burden of different pathogens in acute diarrhoeal episodes among a cohort of Egyptian children less than five years old.

Przeglad gastroenterologiczny

El-Shabrawi M, Salem M, Abou-Zekri M, El-Naghi S, Hassanin F, El-Adly T, El-Shamy A.
PMID: 26516385
Prz Gastroenterol. 2015;10(3):173-80. doi: 10.5114/pg.2015.51186. Epub 2015 Apr 28.

INTRODUCTION: Diarrhoea continues to cause significant morbidity in Egypt.AIM: To determine the frequency and distribution of different enteropathogens in acute diarrhoeal episodes, utilising an expanded testing regimen, and to correlate clinical signs and symptoms associated with the detected pathogens.MATERIAL...

Immunohistochemical clue for the histological overlap of salivary adenoid cystic carcinoma and polymorphous low-grade adenocarcinoma.

Interventional medicine & applied science

El-Nagdy S, Salama NM, Mourad MI.
PMID: 24265903
Interv Med Appl Sci. 2013 Sep;5(3):131-9. doi: 10.1556/IMAS.5.2013.3.6. Epub 2013 Sep 16.

It remains difficult to distinguish adenoid cystic carcinoma (ACC) from polymorphous low-grade adenocarcinoma (PLGA). Although these neoplasms exhibit nearly similar histologic patterns, their biologic behavior is significantly different. This study was carried out in an attempt to overcome the...

Distribution of Iron Oxide Core-Titanium Dioxide Shell Nanoparticles in VX2 Tumor Bearing Rabbits Introduced by Two Different Delivery Modalities.

Nanomaterials (Basel, Switzerland)

Refaat T, West D, El Achy S, Parimi V, May J, Xin L, Harris KR, Liu W, Wanzer MB, Finney L, Maxey E, Vogt S, Omary RA, Procissi D, Larson AC, Paunesku T, Woloschak GE.
PMID: 28335271
Nanomaterials (Basel). 2016 Aug 03;6(8). doi: 10.3390/nano6080143.

This work compares intravenous (IV) versus fluoroscopy-guided transarterial intra-catheter (IC) delivery of iron oxide core-titanium dioxide shell nanoparticles (NPs) in vivo in VX2 model of liver cancer in rabbits. NPs coated with glucose and decorated with a peptide sequence...

Cyclic Dipeptides: The Biological and Structural Landscape with Special Focus on the Anti-Cancer Proline-Based Scaffold.

Biomolecules

Bojarska J, Mieczkowski A, Ziora ZM, Skwarczynski M, Toth I, Shalash AO, Parang K, El-Mowafi SA, Mohammed EHM, Elnagdy S, AlKhazindar M, Wolf WM.
PMID: 34680148
Biomolecules. 2021 Oct 14;11(10). doi: 10.3390/biom11101515.

Cyclic dipeptides, also know as diketopiperazines (DKP), the simplest cyclic forms of peptides widespread in nature, are unsurpassed in their structural and bio-functional diversity. DKPs, especially those containing proline, due to their unique features such as, inter alia, extra-rigid...

Otx2 promotes granule cell precursor proliferation and Shh-dependent medulloblastoma maintenance in vivo.

Oncogenesis

El Nagar S, Chakroun A, Le Greneur C, Figarella-Branger D, Di Meglio T, Lamonerie T, Billon N.
PMID: 30100614
Oncogenesis. 2018 Aug 13;7(8):60. doi: 10.1038/s41389-018-0070-6.

The developmental gene OTX2 is expressed by cerebellar granule cell precursors (GCPs), a cell population which undergoes massive expansion during the early postnatal period in response to sonic hedgehog (Shh). GCPs are thought to be at the origin of...

Showing 1 to 12 of 17 entries